Combining alcohol with antibiotics can increase side effects, toxicity, and long-term health risks. Learn why it's best to avoid alcohol. Read more now!
Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!
The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.
You’ll meet hundreds of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.
Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol.
And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).
The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!
Combining alcohol and antibiotics is a common concern for many individuals. Understanding the interactions, risks, and considerations is crucial for anyone undergoing antibiotic treatment. This article delves into the potential health risks of drinking alcohol while on antibiotics, including increased side effects, heightened toxicity, and long-term health implications.
Antibiotics are powerful medications designed to combat bacterial infections. They work by killing bacteria or inhibiting their growth, allowing the immune system to eliminate the infection. However, antibiotics can also interact with other substances in the body, including alcohol.
Alcohol, a central nervous system depressant, can interfere with the effectiveness of antibiotics and exacerbate their side effects. Understanding these interactions is essential for ensuring the effectiveness of your treatment and maintaining your overall health.
One of the primary concerns with combining alcohol and antibiotics is the increased risk of side effects. Antibiotics already come with a range of potential side effects, such as nausea, vomiting, diarrhea, and dizziness. Adding alcohol into the mix can intensify these symptoms, making the experience more uncomfortable and potentially dangerous.
Certain antibiotics can become more toxic when combined with alcohol. This heightened toxicity can lead to severe health complications and, in some cases, life-threatening conditions.
Chronic alcohol consumption while on antibiotics can have severe long-term health implications. Alcohol can weaken the immune system, making it harder for your body to fight off infections. Additionally, long-term alcohol use can lead to liver damage, which can interfere with the metabolism of antibiotics and other medications.
To ensure the effectiveness of your antibiotic treatment and minimize the risk of adverse effects, it's essential to follow these guidelines:
Combining alcohol and antibiotics can lead to increased side effects, heightened toxicity, and long-term health implications. To ensure the effectiveness of your treatment and protect your overall health, it's best to avoid alcohol while taking antibiotics.
For more detailed information on the risks of mixing alcohol and antibiotics, check out our article on Alcohol and Antibiotics: Understanding the Risks.
Q: Can I drink alcohol while taking antibiotics?A: It's best to avoid alcohol while taking antibiotics to prevent increased side effects, heightened toxicity, and long-term health implications.
Q: What are the risks of combining alcohol and antibiotics?A: Combining alcohol and antibiotics can lead to intensified side effects, increased toxicity, and long-term health issues such as liver damage and immune system suppression.
Q: Are there specific antibiotics that are more dangerous to mix with alcohol?A: Yes, certain antibiotics like metronidazole, cefotetan, and Bactrim can cause severe reactions when combined with alcohol. For more details, read our article on Can You Drink Alcohol On Bactrim?.
Q: What should I do if I experience side effects from mixing alcohol and antibiotics?A: If you experience severe side effects, contact your healthcare provider immediately. They can provide guidance and adjust your treatment plan if necessary.
Q: How long should I wait to drink alcohol after finishing my antibiotics?A: It's generally recommended to wait at least 48-72 hours after finishing your antibiotics before consuming alcohol. However, consult your healthcare provider for specific guidance based on your medication.
Combining alcohol and antibiotics is a common concern for many individuals. Understanding the interactions, risks, and considerations is crucial for anyone undergoing antibiotic treatment. This article delves into the potential health risks of drinking alcohol while on antibiotics, including increased side effects, heightened toxicity, and long-term health implications.
Antibiotics are powerful medications designed to combat bacterial infections. They work by killing bacteria or inhibiting their growth, allowing the immune system to eliminate the infection. However, antibiotics can also interact with other substances in the body, including alcohol.
Alcohol, a central nervous system depressant, can interfere with the effectiveness of antibiotics and exacerbate their side effects. Understanding these interactions is essential for ensuring the effectiveness of your treatment and maintaining your overall health.
One of the primary concerns with combining alcohol and antibiotics is the increased risk of side effects. Antibiotics already come with a range of potential side effects, such as nausea, vomiting, diarrhea, and dizziness. Adding alcohol into the mix can intensify these symptoms, making the experience more uncomfortable and potentially dangerous.
Certain antibiotics can become more toxic when combined with alcohol. This heightened toxicity can lead to severe health complications and, in some cases, life-threatening conditions.
Chronic alcohol consumption while on antibiotics can have severe long-term health implications. Alcohol can weaken the immune system, making it harder for your body to fight off infections. Additionally, long-term alcohol use can lead to liver damage, which can interfere with the metabolism of antibiotics and other medications.
To ensure the effectiveness of your antibiotic treatment and minimize the risk of adverse effects, it's essential to follow these guidelines:
Combining alcohol and antibiotics can lead to increased side effects, heightened toxicity, and long-term health implications. To ensure the effectiveness of your treatment and protect your overall health, it's best to avoid alcohol while taking antibiotics.
For more detailed information on the risks of mixing alcohol and antibiotics, check out our article on Alcohol and Antibiotics: Understanding the Risks.
Q: Can I drink alcohol while taking antibiotics?A: It's best to avoid alcohol while taking antibiotics to prevent increased side effects, heightened toxicity, and long-term health implications.
Q: What are the risks of combining alcohol and antibiotics?A: Combining alcohol and antibiotics can lead to intensified side effects, increased toxicity, and long-term health issues such as liver damage and immune system suppression.
Q: Are there specific antibiotics that are more dangerous to mix with alcohol?A: Yes, certain antibiotics like metronidazole, cefotetan, and Bactrim can cause severe reactions when combined with alcohol. For more details, read our article on Can You Drink Alcohol On Bactrim?.
Q: What should I do if I experience side effects from mixing alcohol and antibiotics?A: If you experience severe side effects, contact your healthcare provider immediately. They can provide guidance and adjust your treatment plan if necessary.
Q: How long should I wait to drink alcohol after finishing my antibiotics?A: It's generally recommended to wait at least 48-72 hours after finishing your antibiotics before consuming alcohol. However, consult your healthcare provider for specific guidance based on your medication.
Combining prednisone with alcohol can exacerbate side effects and lead to serious health risks, including gastrointestinal issues, weakened immune system, and liver damage. Consult your healthcare provider for guidance.
Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!
The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.
You’ll meet hundreds of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.
Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol.
And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).
The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!
Prednisone is a widely used medication prescribed for various inflammatory and autoimmune conditions. While it can be highly effective, combining it with alcohol can lead to complications. This article provides an overview of prednisone, its common uses, mechanism of action, and the potential risks associated with alcohol consumption during treatment.
Prednisone is a synthetic corticosteroid that mimics the effects of cortisol, a hormone naturally produced by the adrenal glands. It is commonly prescribed to reduce inflammation and suppress the immune system in various medical conditions.
Prednisone is used to treat a wide range of conditions, including but not limited to:
Prednisone works by suppressing the immune system and reducing inflammation. It achieves this by:
While prednisone is effective for many conditions, combining it with alcohol can pose significant risks. Understanding these risks is crucial for anyone undergoing treatment with prednisone.
Both prednisone and alcohol can irritate the gastrointestinal (GI) tract. Combining the two can increase the risk of:
Prednisone suppresses the immune system, making it harder for the body to fight infections. Alcohol further weakens the immune system, increasing the risk of infections and slowing down recovery times.
Long-term use of prednisone can lead to osteoporosis, a condition where bones become weak and brittle. Alcohol consumption can also negatively affect bone health, increasing the risk of fractures and osteoporosis.
Both prednisone and alcohol can impact mood and mental health. Prednisone can cause mood swings, anxiety, and depression. Alcohol is a depressant and can exacerbate these mental health issues, leading to a higher risk of emotional instability.
Prednisone is metabolized by the liver, and excessive alcohol consumption can lead to liver damage. Combining the two can put additional strain on the liver, increasing the risk of liver disease.
Prednisone can raise blood sugar levels, which is particularly concerning for individuals with diabetes. Alcohol can also affect blood sugar levels, leading to potential complications in managing diabetes.
Given the potential risks, it is essential to follow safe practices when taking prednisone and considering alcohol consumption.
Always consult your healthcare provider before consuming alcohol while taking prednisone. They can provide personalized advice based on your medical history and current condition.
Be vigilant about monitoring for any side effects when taking prednisone, especially if you consume alcohol. Report any unusual symptoms to your healthcare provider immediately.
If you choose to drink alcohol while taking prednisone, do so in moderation. Limiting alcohol intake can help reduce the risk of adverse effects.
Adopting a healthy lifestyle can help mitigate some of the risks associated with prednisone and alcohol. This includes a balanced diet, regular exercise, and adequate sleep.
It is generally advised to avoid alcohol while taking prednisone due to the increased risk of gastrointestinal issues, weakened immune system, and other potential complications. Consult your healthcare provider for personalized advice.
Combining prednisone and alcohol can increase the risk of gastrointestinal bleeding, weakened immune system, bone health issues, mood swings, liver damage, and blood sugar level fluctuations.
If you choose to drink alcohol while taking prednisone, do so in moderation and consult your healthcare provider for personalized advice. Monitor for any side effects and report them to your healthcare provider.
The time you should wait to drink alcohol after stopping prednisone depends on various factors, including the dosage and duration of prednisone treatment. Consult your healthcare provider for specific guidance.
Several alternatives to prednisone may have fewer interactions with alcohol, but the best option depends on your specific condition and medical history. Discuss alternative treatments with your healthcare provider.
Understanding the interactions between prednisone and alcohol is crucial for anyone undergoing treatment with this medication. By following safe practices and consulting healthcare providers, individuals can minimize risks and ensure effective treatment outcomes.
Prednisone is a widely used medication prescribed for various inflammatory and autoimmune conditions. While it can be highly effective, combining it with alcohol can lead to complications. This article provides an overview of prednisone, its common uses, mechanism of action, and the potential risks associated with alcohol consumption during treatment.
Prednisone is a synthetic corticosteroid that mimics the effects of cortisol, a hormone naturally produced by the adrenal glands. It is commonly prescribed to reduce inflammation and suppress the immune system in various medical conditions.
Prednisone is used to treat a wide range of conditions, including but not limited to:
Prednisone works by suppressing the immune system and reducing inflammation. It achieves this by:
While prednisone is effective for many conditions, combining it with alcohol can pose significant risks. Understanding these risks is crucial for anyone undergoing treatment with prednisone.
Both prednisone and alcohol can irritate the gastrointestinal (GI) tract. Combining the two can increase the risk of:
Prednisone suppresses the immune system, making it harder for the body to fight infections. Alcohol further weakens the immune system, increasing the risk of infections and slowing down recovery times.
Long-term use of prednisone can lead to osteoporosis, a condition where bones become weak and brittle. Alcohol consumption can also negatively affect bone health, increasing the risk of fractures and osteoporosis.
Both prednisone and alcohol can impact mood and mental health. Prednisone can cause mood swings, anxiety, and depression. Alcohol is a depressant and can exacerbate these mental health issues, leading to a higher risk of emotional instability.
Prednisone is metabolized by the liver, and excessive alcohol consumption can lead to liver damage. Combining the two can put additional strain on the liver, increasing the risk of liver disease.
Prednisone can raise blood sugar levels, which is particularly concerning for individuals with diabetes. Alcohol can also affect blood sugar levels, leading to potential complications in managing diabetes.
Given the potential risks, it is essential to follow safe practices when taking prednisone and considering alcohol consumption.
Always consult your healthcare provider before consuming alcohol while taking prednisone. They can provide personalized advice based on your medical history and current condition.
Be vigilant about monitoring for any side effects when taking prednisone, especially if you consume alcohol. Report any unusual symptoms to your healthcare provider immediately.
If you choose to drink alcohol while taking prednisone, do so in moderation. Limiting alcohol intake can help reduce the risk of adverse effects.
Adopting a healthy lifestyle can help mitigate some of the risks associated with prednisone and alcohol. This includes a balanced diet, regular exercise, and adequate sleep.
It is generally advised to avoid alcohol while taking prednisone due to the increased risk of gastrointestinal issues, weakened immune system, and other potential complications. Consult your healthcare provider for personalized advice.
Combining prednisone and alcohol can increase the risk of gastrointestinal bleeding, weakened immune system, bone health issues, mood swings, liver damage, and blood sugar level fluctuations.
If you choose to drink alcohol while taking prednisone, do so in moderation and consult your healthcare provider for personalized advice. Monitor for any side effects and report them to your healthcare provider.
The time you should wait to drink alcohol after stopping prednisone depends on various factors, including the dosage and duration of prednisone treatment. Consult your healthcare provider for specific guidance.
Several alternatives to prednisone may have fewer interactions with alcohol, but the best option depends on your specific condition and medical history. Discuss alternative treatments with your healthcare provider.
Understanding the interactions between prednisone and alcohol is crucial for anyone undergoing treatment with this medication. By following safe practices and consulting healthcare providers, individuals can minimize risks and ensure effective treatment outcomes.
Can you drink on Lamictal (lamotrigine)? Science says it’s not a good idea due to increased side effects and the negative impact of booze on our mental health.
Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!
The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.
You’ll meet hundreds of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.
Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol.
And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).
The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!
We might know her as the charming Princess Leia in her trademark white jumpsuit and iconic “cinnamon buns” hairstyle, but Carrie Fisher had a dark side to her life that many didn’t know about until much later. As she got older, Fisher became more open about her struggles with bipolar disorder, describing it as a roller coaster of emotional states: “Mania starts off fun — not sleeping for days, keeping company with your brain, which has become a wonderful computer, showing 24 TV channels all about you. That goes horribly wrong after a while.”
Fisher also talked about the medications she took for her condition, and her ability to regain some control over her life. “Bipolar disorder can be a great teacher,” she reassured others. “It’s a challenge, but it can set you up to be able to do almost anything else in your life.”
If you’ve had similar experiences, you know that the right medication can make all the difference in dealing with bipolar disorder, and for many, lamotrigine (Lamictal) can be a lifesaver. But can you drink on Lamictal? What are the risks of mixing lamotrigine and alcohol? Let’s find out more.
Lamictal is a medication primarily used to treat epilepsy and bipolar disorder. It works by stabilizing electrical activity in the brain to prevent seizures and mood swings.
According to the National Alliance on Mental Illness, lamotrigine is a mood stabilizer used to treat bipolar disorder (also known as manic depression), as well as certain types of seizure disorders.
Characterized by extreme ups and downs, bipolar disorder can leave us feeling unbalanced and exhausted, unable to find our footing. Here’s an overview of what we might be dealing with.
On the depression side, we might experience some extreme lows:
The other side of the coin — mania — can be just as exhausting in a different way. Here’s what we might experience:
Lamictal can help even out the extremes of depression and mania. That said, it’s considered to be an “off-label” treatment for the condition, meaning that it’s not officially approved by the Food and Drug Administration to be used for this purpose. This means that our healthcare provider should be actively involved in helping us decide if Lamictal is right for us or if a different treatment option would be more appropriate.
Now that we have an idea of what Lamictal is and what it’s used for, let’s explore why mixing lamotrigine and alcohol is not a good idea.
Common side effects of Lamictal don’t mix well with alcohol:
As we can see, the side effects of Lamictal and alcohol tend to increase if we mix the two. But that’s not the only reason to steer clear of the combo.
Another reason why mixing Lamictal and alcohol could lead to trouble? Alcohol (as well as alcohol withdrawal) can be a seizure trigger. And if we’re taking Lamictal to prevent seizures, adding booze to the mix could be counterproductive.
Finally, alcohol’s negative effect on our mental health is another reason why the Lamictal-alcohol combo could land us in dangerous waters.
With all of the ways alcohol can interfere with our mental health, mixing Lamictal and booze is counterproductive, to say the least. If we weren’t convinced before, the situation should be pretty clear by now: drinking on Lamictal is not a good idea.
You might be wondering, just how serious is mixing Lamictal and alcohol? Before you start Googling, “Can lamotrigine and alcohol kill you?” take a deep breath. The answer is — probably not.
But you should still be careful. According to the NHS, “During the first few days of taking lamotrigine, it's best to stop drinking alcohol until you see how the medicine affects you.”
And now, here are some tips to stay safe and take care of your mental health while taking Lamictal:
And remember, Reframe is here to help you every step of the way! Check out our 24/7 Forum to connect with people just like you. Many of our users have experience dealing with mental health struggles as they explore their relationship with alcohol and can offer valuable support and advice.
In the end, taking charge of your mental health is a sign of strength. Congratulations on making an active effort! Remember, many people — including Carrie Fisher and others who have struggled with bipolar symptoms — have found a way out. Let’s continue to shed light on these challenges as we find solutions together.
We might know her as the charming Princess Leia in her trademark white jumpsuit and iconic “cinnamon buns” hairstyle, but Carrie Fisher had a dark side to her life that many didn’t know about until much later. As she got older, Fisher became more open about her struggles with bipolar disorder, describing it as a roller coaster of emotional states: “Mania starts off fun — not sleeping for days, keeping company with your brain, which has become a wonderful computer, showing 24 TV channels all about you. That goes horribly wrong after a while.”
Fisher also talked about the medications she took for her condition, and her ability to regain some control over her life. “Bipolar disorder can be a great teacher,” she reassured others. “It’s a challenge, but it can set you up to be able to do almost anything else in your life.”
If you’ve had similar experiences, you know that the right medication can make all the difference in dealing with bipolar disorder, and for many, lamotrigine (Lamictal) can be a lifesaver. But can you drink on Lamictal? What are the risks of mixing lamotrigine and alcohol? Let’s find out more.
Lamictal is a medication primarily used to treat epilepsy and bipolar disorder. It works by stabilizing electrical activity in the brain to prevent seizures and mood swings.
According to the National Alliance on Mental Illness, lamotrigine is a mood stabilizer used to treat bipolar disorder (also known as manic depression), as well as certain types of seizure disorders.
Characterized by extreme ups and downs, bipolar disorder can leave us feeling unbalanced and exhausted, unable to find our footing. Here’s an overview of what we might be dealing with.
On the depression side, we might experience some extreme lows:
The other side of the coin — mania — can be just as exhausting in a different way. Here’s what we might experience:
Lamictal can help even out the extremes of depression and mania. That said, it’s considered to be an “off-label” treatment for the condition, meaning that it’s not officially approved by the Food and Drug Administration to be used for this purpose. This means that our healthcare provider should be actively involved in helping us decide if Lamictal is right for us or if a different treatment option would be more appropriate.
Now that we have an idea of what Lamictal is and what it’s used for, let’s explore why mixing lamotrigine and alcohol is not a good idea.
Common side effects of Lamictal don’t mix well with alcohol:
As we can see, the side effects of Lamictal and alcohol tend to increase if we mix the two. But that’s not the only reason to steer clear of the combo.
Another reason why mixing Lamictal and alcohol could lead to trouble? Alcohol (as well as alcohol withdrawal) can be a seizure trigger. And if we’re taking Lamictal to prevent seizures, adding booze to the mix could be counterproductive.
Finally, alcohol’s negative effect on our mental health is another reason why the Lamictal-alcohol combo could land us in dangerous waters.
With all of the ways alcohol can interfere with our mental health, mixing Lamictal and booze is counterproductive, to say the least. If we weren’t convinced before, the situation should be pretty clear by now: drinking on Lamictal is not a good idea.
You might be wondering, just how serious is mixing Lamictal and alcohol? Before you start Googling, “Can lamotrigine and alcohol kill you?” take a deep breath. The answer is — probably not.
But you should still be careful. According to the NHS, “During the first few days of taking lamotrigine, it's best to stop drinking alcohol until you see how the medicine affects you.”
And now, here are some tips to stay safe and take care of your mental health while taking Lamictal:
And remember, Reframe is here to help you every step of the way! Check out our 24/7 Forum to connect with people just like you. Many of our users have experience dealing with mental health struggles as they explore their relationship with alcohol and can offer valuable support and advice.
In the end, taking charge of your mental health is a sign of strength. Congratulations on making an active effort! Remember, many people — including Carrie Fisher and others who have struggled with bipolar symptoms — have found a way out. Let’s continue to shed light on these challenges as we find solutions together.
Wondering if Xarelto and alcohol are a dangerous mix? Learn the science behind the risks of this combo in our latest blog!
Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!
The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.
You’ll meet hundreds of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.
Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol.
And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).
The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!
Gone are the days when “medicine” meant bloodletting, leeches, or (yikes!) trepanation. And thank goodness for that. While our ancestors tried their best, it took humankind some time to figure out that having slimy critters suck our blood or drilling holes in the skulls of suffering patients would probably do more harm than good. Well, as they say, you live and learn.
However, now that we have medications to treat all kinds of problems — including sophisticated ones such as rivaroxaban (Xarelto) that target cardiovascular issues — we’re faced with a different dilemma. You might be asking yourself, Is it okay to mix them with booze? Specifically, can you drink alcohol while taking Xarelto? And how long does Xarelto stay in your system? Let’s find out!
Xarelto is a widely used anticoagulant medication prescribed to prevent blood clots in patients with atrial fibrillation, deep vein thrombosis (DVT), and pulmonary embolism (PE). It’s also used to prevent stroke.
Anticoagulants belong to a larger group of medications known as blood thinners. As the name suggests, blood thinners, well, thin our blood — sort of. More precisely, they prevent excessive clots from forming in our blood and blocking blood flow in critical locations of the body, such as the heart, lungs, or brain.
There are two basic types of blood thinners that work in slightly different ways:
Like any medication, Xarelto comes with instructions we should make sure to follow. If we have questions, it’s important to always ask our doctor or pharmacist for advice.
For now though, let’s focus on the question that’s on our mind today: What happens if we mix alcohol and Xarelto?
It’s not a good idea to combine Xarelto and alcohol. Here are the main reasons why Xarelto and alcohol are not a good mix.
Many of Xarelto’s side effects don’t mix well with booze.
As we can see, the combination of Xarelto and alcohol can leave us feeling less than stellar. Plus, the double dose of dizziness and breathing difficulties could be dangerous!
In spite of what some headlines might imply, alcohol isn’t as heart-friendly as we once thought. In fact, it can cause heart palpitations, send our blood pressure haywire (by causing dips followed by rebound spikes), and it can even cause serious heart disease in the long run. So drinking while trying to treat our vascular health problems can be counterproductive, to say the least.
Xarelto is processed by the liver, and adding alcohol to the mix could create a heavier burden. While the liver can certainly multitask, it has a limit. (For more information, check out “How Much Alcohol Causes Liver Damage?”).
Last (but certainly not least), alcohol has an effect on our blood, and combining alcohol and Xarelto increases the risk of bleeding. Science shows that drinking increases our risk of gastrointestinal bleeding and even amps up the risk of hemorrhagic stroke caused by bleeding in the brain. (For more insights, see “What Does Alcohol Do to Your Blood?”)
Alcohol isn’t the only substance that can increase our chances of bleeding when taking Xarelto. Here are more to be careful with:
In addition to other substances, any activities that increase our chances of bleeding are ones to be careful with (more on that below!)
When is it “safe” to drink after taking Xarelto? It depends.
Xarelto has a half-life of about 5 to 9 hours in younger folks and 13 to 15 in older adults. That means that it’s out of our system completely within about two days.
But while it’s technically “safe” to drink after the two-day mark, there are other factors to consider before getting in line for that margarita at happy hour. For example, if we’re concerned about our vascular health, booze might not be our best option. If we’re recovering from an injury or illness, it could delay our recovery. And if we’ve been on Xarelto or other medications for a while, we might want to give our liver a much-needed break.
To finish off, here are some tips to stay safe and healthy while taking Xarelto:
With these tips, you can stay safe while taking Xarelto. They’re also great for staying safe and healthy in general. Vascular health is important for all of us, and prevention is always a good idea.
In the end, Xarelto, alcohol, and vascular health in general are all important pieces of the puzzle to consider when it comes to our overall wellness. Let’s give our body and mind a chance to function at their best! In the wise words of Thomas Carlyle, “He who has health, has hope; and he who has hope, has everything.”
Gone are the days when “medicine” meant bloodletting, leeches, or (yikes!) trepanation. And thank goodness for that. While our ancestors tried their best, it took humankind some time to figure out that having slimy critters suck our blood or drilling holes in the skulls of suffering patients would probably do more harm than good. Well, as they say, you live and learn.
However, now that we have medications to treat all kinds of problems — including sophisticated ones such as rivaroxaban (Xarelto) that target cardiovascular issues — we’re faced with a different dilemma. You might be asking yourself, Is it okay to mix them with booze? Specifically, can you drink alcohol while taking Xarelto? And how long does Xarelto stay in your system? Let’s find out!
Xarelto is a widely used anticoagulant medication prescribed to prevent blood clots in patients with atrial fibrillation, deep vein thrombosis (DVT), and pulmonary embolism (PE). It’s also used to prevent stroke.
Anticoagulants belong to a larger group of medications known as blood thinners. As the name suggests, blood thinners, well, thin our blood — sort of. More precisely, they prevent excessive clots from forming in our blood and blocking blood flow in critical locations of the body, such as the heart, lungs, or brain.
There are two basic types of blood thinners that work in slightly different ways:
Like any medication, Xarelto comes with instructions we should make sure to follow. If we have questions, it’s important to always ask our doctor or pharmacist for advice.
For now though, let’s focus on the question that’s on our mind today: What happens if we mix alcohol and Xarelto?
It’s not a good idea to combine Xarelto and alcohol. Here are the main reasons why Xarelto and alcohol are not a good mix.
Many of Xarelto’s side effects don’t mix well with booze.
As we can see, the combination of Xarelto and alcohol can leave us feeling less than stellar. Plus, the double dose of dizziness and breathing difficulties could be dangerous!
In spite of what some headlines might imply, alcohol isn’t as heart-friendly as we once thought. In fact, it can cause heart palpitations, send our blood pressure haywire (by causing dips followed by rebound spikes), and it can even cause serious heart disease in the long run. So drinking while trying to treat our vascular health problems can be counterproductive, to say the least.
Xarelto is processed by the liver, and adding alcohol to the mix could create a heavier burden. While the liver can certainly multitask, it has a limit. (For more information, check out “How Much Alcohol Causes Liver Damage?”).
Last (but certainly not least), alcohol has an effect on our blood, and combining alcohol and Xarelto increases the risk of bleeding. Science shows that drinking increases our risk of gastrointestinal bleeding and even amps up the risk of hemorrhagic stroke caused by bleeding in the brain. (For more insights, see “What Does Alcohol Do to Your Blood?”)
Alcohol isn’t the only substance that can increase our chances of bleeding when taking Xarelto. Here are more to be careful with:
In addition to other substances, any activities that increase our chances of bleeding are ones to be careful with (more on that below!)
When is it “safe” to drink after taking Xarelto? It depends.
Xarelto has a half-life of about 5 to 9 hours in younger folks and 13 to 15 in older adults. That means that it’s out of our system completely within about two days.
But while it’s technically “safe” to drink after the two-day mark, there are other factors to consider before getting in line for that margarita at happy hour. For example, if we’re concerned about our vascular health, booze might not be our best option. If we’re recovering from an injury or illness, it could delay our recovery. And if we’ve been on Xarelto or other medications for a while, we might want to give our liver a much-needed break.
To finish off, here are some tips to stay safe and healthy while taking Xarelto:
With these tips, you can stay safe while taking Xarelto. They’re also great for staying safe and healthy in general. Vascular health is important for all of us, and prevention is always a good idea.
In the end, Xarelto, alcohol, and vascular health in general are all important pieces of the puzzle to consider when it comes to our overall wellness. Let’s give our body and mind a chance to function at their best! In the wise words of Thomas Carlyle, “He who has health, has hope; and he who has hope, has everything.”
Is it safe to drink alcohol if you take sleeping pills occasionally or are prescribed sleeping pills? Find out the risks associated with this dangerous combo.
Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!
The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.
You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.
Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol.
And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).
The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!
You’re experiencing problems sleeping and have been prescribed sleeping pills. Your doctor warns you about the risks associated with drinking alcohol while taking sleeping pills, but you’re wondering if this means you have to give up alcohol completely. Can it be that risky to mix the two? What if you only have one drink?
Find out the facts and risks of mixing sleeping pills with alcohol as we explore this topic together.
Sleeping pills are medications used to treat insomnia, restless sleep, or difficulty falling asleep. There are many different sleeping pills, each with a unique chemical structure and pharmacological effect.
Those frequently prescribed are:
There are also over-the-counter sleep aids and medications known to induce sleepiness as a side effect:
Both prescription and over-the-counter sleeping pills work by slowing down our central nervous system and brain activity. There are different types of sleeping pills out there, but they all basically have the same effects. Most sleep aids take effect 30 minutes after intake and last up to eight hours, but some are made to have an extended release, meaning the effects take longer to manifest and may last longer.
Sleeping pills are used to initiate, sustain, or lengthen sleep. In a survey published by the Centers for Disease Control and Prevention (CDC), roughly 8.4% of adults reported using sleep medication every day or most days of the week in the last 30 days. When used as directed, these medications bring much-needed relief from sleep problems, sleep disorders, and insomnia.
The answer to this may seem pretty obvious: sleeping pills are used to help us sleep. Right? Well, there’s a little more to it than that.
There are many possible origins of sleep problems, and each comes with its own unique set of challenges. Let’s take a look:.
Any one of these root causes has the potential to interfere with sleep dramatically, producing the umbrella condition known as insomnia.
From the Latin words “in-” meaning “not” and “somnius” meaning “sleep,” insomnia is pretty straightforward: it means difficulty or inability to sleep. Just about every human being will experience insomnia at some point in their lives, whether it’s a period of insomnia or just an occasional night lying awake. At any given time, 1 in 3 adults are experiencing insomnia symptoms.
Nights of insomnia can produce difficult, low-energy days that seem to drag on forever. Chronic insomnia puts a lot of strain on our health, work life, mental well-being, family life, and relationships. In the 1999 film Fight Club, the protagonist describes it perfectly: “With insomnia, nothing is real. Everything is far away. Everything is a copy of a copy of a copy.”
Those of us with chronic insomnia may start to take drastic measures to get some sleep (although hopefully not as drastic as the ones in Fight Club!). Luckily, sleeping pills are easily available, effective, and safe when taken as directed. However, we may decide to take matters into our own hands if we feel they’re not working well enough (or if we want to solve things without seeing a doctor). In that pursuit, we may end up making some potentially dangerous or harmful decisions.
Mixing alcohol with any medication is risky enough. Combining any two medications poses the risk of interactions, and alcohol interacts with a lot of medications. This is because alcohol is a central nervous system depressant, meaning it slows down our brain signals, making us sleepy, uncoordinated, slow, and foggy. Because it’s a sedative, alcohol can exacerbate the sedative effects of sleeping pills, making us drowsy and slowing down our heart rate and other normal bodily functions to dangerously low levels.
The bottom line is, it is never safe to mix alcohol with sleeping pills — let’s further explore a few of the most important reasons why.
The overdose potential from mixing sleeping pills and alcohol should not be taken lightly. Studies show that many common sleeping pills can be deadly when mixed with alcohol, especially if too much of either substance is used. Even without alcohol in the equation, it’s important to always take only the prescribed dose of sleeping pills and to carefully read the warning labels on over-the-counter sleeping medications.
Death can occur when the combination of sleeping pills and alcohol suppresses our respiratory rate to a dangerously low level, or if this combination affects the heart. But the dangers go beyond that — in fact, it may be more likely for death to occur as the result of impaired alertness, judgment, or coordination. These impairments make seemingly simple activities like swimming, driving, or crossing the road potentially deadly.
Mixing sleeping pills and alcohol can also lead to sleepwalking and impaired memory. There are several documented cases of people sleepwalking, sleep-eating, and even sleep-driving on the popular sleeping medication Ambien, and they don’t always remember what they did when they wake up. Scary!
When alcohol is mixed with a medication like Ambien, the effects are worse. These episodes could result in injury or, in some situations (such as sleep-driving), may lead to arrest or harm to others.
Believe it or not, excessive or chronic alcohol use can actually cause insomnia! As a depressant, alcohol slows down our central nervous system, making us sleepy/relaxed. As our body metabolizes alcohol, we experience a rebound effect. In an attempt to rebalance itself, our brain releases neurotransmitters to wake us back up. This ends up disrupting our sleep, especially the deep, restorative sleep we need for our brain to function properly.
So in addition to being dangerous, it’s also counterproductive to mix a sleep aid and alcohol.
The best way to avoid the dangers of mixing sleeping pills and alcohol is to avoid alcohol completely. There are many other ways to improve our sleep or boost the effectiveness of our sleeping pills without negative (or dangerous) side effects.
The bottom line is alcohol and sleeping pills should never be mixed. While alcohol and medications are a dangerous combo in general, sleeping pills and alcohol can be very dangerous — and even deadly — if taken together. It’s not worth the risk!
You’re experiencing problems sleeping and have been prescribed sleeping pills. Your doctor warns you about the risks associated with drinking alcohol while taking sleeping pills, but you’re wondering if this means you have to give up alcohol completely. Can it be that risky to mix the two? What if you only have one drink?
Find out the facts and risks of mixing sleeping pills with alcohol as we explore this topic together.
Sleeping pills are medications used to treat insomnia, restless sleep, or difficulty falling asleep. There are many different sleeping pills, each with a unique chemical structure and pharmacological effect.
Those frequently prescribed are:
There are also over-the-counter sleep aids and medications known to induce sleepiness as a side effect:
Both prescription and over-the-counter sleeping pills work by slowing down our central nervous system and brain activity. There are different types of sleeping pills out there, but they all basically have the same effects. Most sleep aids take effect 30 minutes after intake and last up to eight hours, but some are made to have an extended release, meaning the effects take longer to manifest and may last longer.
Sleeping pills are used to initiate, sustain, or lengthen sleep. In a survey published by the Centers for Disease Control and Prevention (CDC), roughly 8.4% of adults reported using sleep medication every day or most days of the week in the last 30 days. When used as directed, these medications bring much-needed relief from sleep problems, sleep disorders, and insomnia.
The answer to this may seem pretty obvious: sleeping pills are used to help us sleep. Right? Well, there’s a little more to it than that.
There are many possible origins of sleep problems, and each comes with its own unique set of challenges. Let’s take a look:.
Any one of these root causes has the potential to interfere with sleep dramatically, producing the umbrella condition known as insomnia.
From the Latin words “in-” meaning “not” and “somnius” meaning “sleep,” insomnia is pretty straightforward: it means difficulty or inability to sleep. Just about every human being will experience insomnia at some point in their lives, whether it’s a period of insomnia or just an occasional night lying awake. At any given time, 1 in 3 adults are experiencing insomnia symptoms.
Nights of insomnia can produce difficult, low-energy days that seem to drag on forever. Chronic insomnia puts a lot of strain on our health, work life, mental well-being, family life, and relationships. In the 1999 film Fight Club, the protagonist describes it perfectly: “With insomnia, nothing is real. Everything is far away. Everything is a copy of a copy of a copy.”
Those of us with chronic insomnia may start to take drastic measures to get some sleep (although hopefully not as drastic as the ones in Fight Club!). Luckily, sleeping pills are easily available, effective, and safe when taken as directed. However, we may decide to take matters into our own hands if we feel they’re not working well enough (or if we want to solve things without seeing a doctor). In that pursuit, we may end up making some potentially dangerous or harmful decisions.
Mixing alcohol with any medication is risky enough. Combining any two medications poses the risk of interactions, and alcohol interacts with a lot of medications. This is because alcohol is a central nervous system depressant, meaning it slows down our brain signals, making us sleepy, uncoordinated, slow, and foggy. Because it’s a sedative, alcohol can exacerbate the sedative effects of sleeping pills, making us drowsy and slowing down our heart rate and other normal bodily functions to dangerously low levels.
The bottom line is, it is never safe to mix alcohol with sleeping pills — let’s further explore a few of the most important reasons why.
The overdose potential from mixing sleeping pills and alcohol should not be taken lightly. Studies show that many common sleeping pills can be deadly when mixed with alcohol, especially if too much of either substance is used. Even without alcohol in the equation, it’s important to always take only the prescribed dose of sleeping pills and to carefully read the warning labels on over-the-counter sleeping medications.
Death can occur when the combination of sleeping pills and alcohol suppresses our respiratory rate to a dangerously low level, or if this combination affects the heart. But the dangers go beyond that — in fact, it may be more likely for death to occur as the result of impaired alertness, judgment, or coordination. These impairments make seemingly simple activities like swimming, driving, or crossing the road potentially deadly.
Mixing sleeping pills and alcohol can also lead to sleepwalking and impaired memory. There are several documented cases of people sleepwalking, sleep-eating, and even sleep-driving on the popular sleeping medication Ambien, and they don’t always remember what they did when they wake up. Scary!
When alcohol is mixed with a medication like Ambien, the effects are worse. These episodes could result in injury or, in some situations (such as sleep-driving), may lead to arrest or harm to others.
Believe it or not, excessive or chronic alcohol use can actually cause insomnia! As a depressant, alcohol slows down our central nervous system, making us sleepy/relaxed. As our body metabolizes alcohol, we experience a rebound effect. In an attempt to rebalance itself, our brain releases neurotransmitters to wake us back up. This ends up disrupting our sleep, especially the deep, restorative sleep we need for our brain to function properly.
So in addition to being dangerous, it’s also counterproductive to mix a sleep aid and alcohol.
The best way to avoid the dangers of mixing sleeping pills and alcohol is to avoid alcohol completely. There are many other ways to improve our sleep or boost the effectiveness of our sleeping pills without negative (or dangerous) side effects.
The bottom line is alcohol and sleeping pills should never be mixed. While alcohol and medications are a dangerous combo in general, sleeping pills and alcohol can be very dangerous — and even deadly — if taken together. It’s not worth the risk!
Lexapro is a common medication used to treat anxiety and depression. While it’s relatively safe, drinking alcohol on Lexapro can cause some interactions. Learn more in our latest blog!
Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!
The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.
You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.
Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol.
And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).
The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!
We finally decided to take control of our mental health! We’re seeing a psychiatrist, and they’ve prescribed Lexapro for our anxiety and depression. Not much changed at first, but after about a month, it kicked in! We’re starting to feel more relaxed, and we’re enjoying the things we loved again. We want to do something fun. Maybe we should go out with some friends? Can we drink on Lexapro — or skip a dose to drink?
In this article, we’ll learn that drinking alcohol while on Lexapro can make our symptoms of anxiety and depression worse. And we’ll learn the science behind Lexapro and alcohol — and what happens if we mix them.
Approximately 1 in 4 people have a mental health condition. Anxiety and depression are two of the most common: nearly 18% of people in the U.S. have a diagnosed anxiety disorder while 9.5% have been diagnosed with depression.
Anxiety is something most of us have experienced because it is essentially our normal way of adapting to stress or danger. Anxiety becomes an issue when we have excessive, persistent, and uncontrollable worry. There is a range of anxiety disorders, but among those most commonly diagnosed are generalized anxiety disorder (GAD), social anxiety disorder, panic disorder, and specific phobias. Although these disorders have their own criteria and symptoms, some shared symptoms of anxiety disorders are excessive worrying, restlessness, muscle tension, difficulty concentrating, irritability, sleep problems, increased heart rate, and sweating.
We may all experience ups and downs, but depression goes beyond the normal lows. Depression is a mood disorder that is characterized by persistent feelings of sadness, hopelessness, and emptiness. The most common depressive disorders include major depressive disorder (MDD), persistent disorder, bipolar disorder, and seasonal affective disorder (SAD). Symptoms of depressive disorders include loss of interest in pleasurable activities, changes in appetite, changes in sleep patterns, fatigue, feeling worthless or guilty, difficulty concentrating, and thoughts of death or suicide. To be diagnosed with a depressive disorder, we must experience these symptoms for at least two weeks, and the condition has to be interfering with our daily functioning.
In both anxiety and depression, our brain lacks an important neurotransmitter, serotonin. A neurotransmitter is a chemical that our brain uses for communication. Serotonin is the “mood regulator” chemical in our brain, so when serotonin is in low supply, we can become depressed or anxious. It is important to remember how complex our brain is and, although serotonin is a key component of depression and anxiety, other chemicals also contribute to these disorders, including dopamine, gamma-aminobutyric acid (GABA), and norepinephrine.
Lexapro is the brand name medication for escitalopram, a selective serotonin reuptake inhibitor (SSRI). SSRIs are a class of medications known as antidepressants. Lexapro is primarily used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD) by increasing the amount of serotonin in the brain. As an SSRI, Lexapro inhibits the reuptake of serotonin, but what does that actually mean?
A neurotransmitter, serotonin is released into synapses, the tiny spaces between cells in our brain (neurons). Here, the serotonin will find nearby neurons to bind with, but not all of the serotonin that is released is used so there is extra in the synapse. The excess serotonin will get reabsorbed into the neuron it was released from through a process called reuptake. So, because SSRIs prevent reuptake, more serotonin is left in the synapse to bind with other neurons. This is advantageous for those with anxiety and depressive disorders who have lower levels of serotonin.
Although Lexapro can be successful in treating MDD and GAD, a host of side effects are associated with the medication. Let’s review some common side effects of escitalopram.
Most side effects will resolve within a few weeks of starting Lexapro. If they do not, talk to your medical provider. There are some rare but serious side effects associated with Lexapro, including seizures, dizziness, trouble breathing, fast or irregular heartbeat, and confusion. Seek immediate medical attention if you experience any of these symptoms.
Alcohol is a depressant, meaning it slows down certain brain activity and makes us feel relaxed and euphoric — at first. However, after the initial relaxing feelings, we can begin to feel more anxious and/or depressed. Alcohol can intensify our feelings of sadness, anxiety, and irritability. Chronic alcohol use increases our risk of developing depression or anxiety disorders.
Alcohol slows our brain primarily through mechanisms associated with GABA, the primary inhibitory neurotransmitter in our brain. As we drink alcohol, levels of GABA increase. However, alcohol also affects other neurotransmitters such as dopamine and serotonin — both of which are increased after drinking alcohol. Long-term alcohol use alters our brain and the neurotransmitter system to compensate for the initial increases of GABA, dopamine, and serotonin. But, over time, GABA, dopamine, and serotonin levels and actions are decreased. These changes continue to worsen our depression and anxiety with chronic alcohol use.
Alcohol and Lexapro both affect our serotonin system. As we’ve learned, Lexapro blocks the reuptake of serotonin. As we first consume alcohol, serotonin levels increase. As alcohol and Lexapro interact, the side effects of each may increase. The following are some symptoms we may experience if we drink alcohol while taking escitalopram:
These symptoms are typical of alcohol use, but our chances of experiencing them — and more intensely — increase when we combine Lexapro and alcohol. So, should you drink on Lexapro? Let’s look into the risks.
There are several risks associated with mixing Lexapro and alcohol. Let’s review them.
Not everyone taking Lexapro will experience these risks. Those of us who are on a higher dose of Lexapro or who drink more alcohol are at greater risk of developing more severe symptoms when mixing the two. We know the associated risks and how Lexapro and alcohol interact, but let’s get down to whether you can drink while taking Lexapro for anxiety and depression.
Most doctors recommend avoiding alcohol while on Lexapro. However, based on the information here, we still might wonder, can I have an occasional drink while on Lexapro?
Short answer, yes ... but — we should also consult with our prescribing medical professional before we consume alcohol. If our symptoms of depression and anxiety are well managed, having one or two drinks while taking Lexapro will likely not lead to immediate harm. The key is moderation — limiting our overall alcohol intake, drinking slowly, and and eating food beforehand.
We should never skip a dose of Lexapro to drink alcohol! In fact, we should never go off Lexapro without consulting a physician. Going off Lexapro requires us to gradually reduce the amount we take so we don’t experience withdrawal symptoms. Lexapro withdrawal symptoms include increased anxiety, confusion, dizziness, headaches, irritability, nausea, trouble sleeping, unusual tiredness, burning or tingling, and brain zaps.
If, after checking with your doctor, you decide it’s best to avoid alcohol while on Lexapro, what are some alternatives to alcohol?
We finally decided to take control of our mental health! We’re seeing a psychiatrist, and they’ve prescribed Lexapro for our anxiety and depression. Not much changed at first, but after about a month, it kicked in! We’re starting to feel more relaxed, and we’re enjoying the things we loved again. We want to do something fun. Maybe we should go out with some friends? Can we drink on Lexapro — or skip a dose to drink?
In this article, we’ll learn that drinking alcohol while on Lexapro can make our symptoms of anxiety and depression worse. And we’ll learn the science behind Lexapro and alcohol — and what happens if we mix them.
Approximately 1 in 4 people have a mental health condition. Anxiety and depression are two of the most common: nearly 18% of people in the U.S. have a diagnosed anxiety disorder while 9.5% have been diagnosed with depression.
Anxiety is something most of us have experienced because it is essentially our normal way of adapting to stress or danger. Anxiety becomes an issue when we have excessive, persistent, and uncontrollable worry. There is a range of anxiety disorders, but among those most commonly diagnosed are generalized anxiety disorder (GAD), social anxiety disorder, panic disorder, and specific phobias. Although these disorders have their own criteria and symptoms, some shared symptoms of anxiety disorders are excessive worrying, restlessness, muscle tension, difficulty concentrating, irritability, sleep problems, increased heart rate, and sweating.
We may all experience ups and downs, but depression goes beyond the normal lows. Depression is a mood disorder that is characterized by persistent feelings of sadness, hopelessness, and emptiness. The most common depressive disorders include major depressive disorder (MDD), persistent disorder, bipolar disorder, and seasonal affective disorder (SAD). Symptoms of depressive disorders include loss of interest in pleasurable activities, changes in appetite, changes in sleep patterns, fatigue, feeling worthless or guilty, difficulty concentrating, and thoughts of death or suicide. To be diagnosed with a depressive disorder, we must experience these symptoms for at least two weeks, and the condition has to be interfering with our daily functioning.
In both anxiety and depression, our brain lacks an important neurotransmitter, serotonin. A neurotransmitter is a chemical that our brain uses for communication. Serotonin is the “mood regulator” chemical in our brain, so when serotonin is in low supply, we can become depressed or anxious. It is important to remember how complex our brain is and, although serotonin is a key component of depression and anxiety, other chemicals also contribute to these disorders, including dopamine, gamma-aminobutyric acid (GABA), and norepinephrine.
Lexapro is the brand name medication for escitalopram, a selective serotonin reuptake inhibitor (SSRI). SSRIs are a class of medications known as antidepressants. Lexapro is primarily used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD) by increasing the amount of serotonin in the brain. As an SSRI, Lexapro inhibits the reuptake of serotonin, but what does that actually mean?
A neurotransmitter, serotonin is released into synapses, the tiny spaces between cells in our brain (neurons). Here, the serotonin will find nearby neurons to bind with, but not all of the serotonin that is released is used so there is extra in the synapse. The excess serotonin will get reabsorbed into the neuron it was released from through a process called reuptake. So, because SSRIs prevent reuptake, more serotonin is left in the synapse to bind with other neurons. This is advantageous for those with anxiety and depressive disorders who have lower levels of serotonin.
Although Lexapro can be successful in treating MDD and GAD, a host of side effects are associated with the medication. Let’s review some common side effects of escitalopram.
Most side effects will resolve within a few weeks of starting Lexapro. If they do not, talk to your medical provider. There are some rare but serious side effects associated with Lexapro, including seizures, dizziness, trouble breathing, fast or irregular heartbeat, and confusion. Seek immediate medical attention if you experience any of these symptoms.
Alcohol is a depressant, meaning it slows down certain brain activity and makes us feel relaxed and euphoric — at first. However, after the initial relaxing feelings, we can begin to feel more anxious and/or depressed. Alcohol can intensify our feelings of sadness, anxiety, and irritability. Chronic alcohol use increases our risk of developing depression or anxiety disorders.
Alcohol slows our brain primarily through mechanisms associated with GABA, the primary inhibitory neurotransmitter in our brain. As we drink alcohol, levels of GABA increase. However, alcohol also affects other neurotransmitters such as dopamine and serotonin — both of which are increased after drinking alcohol. Long-term alcohol use alters our brain and the neurotransmitter system to compensate for the initial increases of GABA, dopamine, and serotonin. But, over time, GABA, dopamine, and serotonin levels and actions are decreased. These changes continue to worsen our depression and anxiety with chronic alcohol use.
Alcohol and Lexapro both affect our serotonin system. As we’ve learned, Lexapro blocks the reuptake of serotonin. As we first consume alcohol, serotonin levels increase. As alcohol and Lexapro interact, the side effects of each may increase. The following are some symptoms we may experience if we drink alcohol while taking escitalopram:
These symptoms are typical of alcohol use, but our chances of experiencing them — and more intensely — increase when we combine Lexapro and alcohol. So, should you drink on Lexapro? Let’s look into the risks.
There are several risks associated with mixing Lexapro and alcohol. Let’s review them.
Not everyone taking Lexapro will experience these risks. Those of us who are on a higher dose of Lexapro or who drink more alcohol are at greater risk of developing more severe symptoms when mixing the two. We know the associated risks and how Lexapro and alcohol interact, but let’s get down to whether you can drink while taking Lexapro for anxiety and depression.
Most doctors recommend avoiding alcohol while on Lexapro. However, based on the information here, we still might wonder, can I have an occasional drink while on Lexapro?
Short answer, yes ... but — we should also consult with our prescribing medical professional before we consume alcohol. If our symptoms of depression and anxiety are well managed, having one or two drinks while taking Lexapro will likely not lead to immediate harm. The key is moderation — limiting our overall alcohol intake, drinking slowly, and and eating food beforehand.
We should never skip a dose of Lexapro to drink alcohol! In fact, we should never go off Lexapro without consulting a physician. Going off Lexapro requires us to gradually reduce the amount we take so we don’t experience withdrawal symptoms. Lexapro withdrawal symptoms include increased anxiety, confusion, dizziness, headaches, irritability, nausea, trouble sleeping, unusual tiredness, burning or tingling, and brain zaps.
If, after checking with your doctor, you decide it’s best to avoid alcohol while on Lexapro, what are some alternatives to alcohol?
Naltrexone and Suboxone are two common medications used to treat substance use disorder. But do they work together? Learn more about naltrexone and Suboxone in our latest blog.
Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!
The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.
You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.
Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol.
And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).
The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!
Ever heard of the saying “the more the merrier”? While this may be true for laughter and love, the same can’t be said for naltrexone and Suboxone. Naltrexone and Suboxone are two common medications used to treat substance use disorders and can commonly be mistaken as one and the same.
Recovering from substance dependence is no cakewalk, and unpleasant withdrawal symptoms may have us wondering if taking both naltrexone and Suboxone can help. This strategy may have worked that time we needed an extra Tylenol for that unusually unbearable headache, but with naltrexone and Suboxone, double dipping can cause detrimental effects.
For those of us who are recovering from substance dependence, it’s worth exploring all possible solutions to help us reach our end goal. Having better knowledge of what naltrexone and Suboxone are and how they work helps us understand why they don’t go hand-in-hand. Let’s get into some alternative strategies for how to navigate substance use recovery, but first, let’s understand more about the combination of naltrexone and Suboxone to help cross it off the list for possible solutions.
Naltrexone is a type of drug known as an opioid antagonist, meaning it blocks the action of opioids. It’s approved by the Food and Drug Administration (FDA) as a medication to treat alcohol use disorder (AUD) and opioid use disorder (OUD). Naltrexone works by blocking opioid receptors in our brain — effectively getting rid of the intoxication effects of alcohol and opioids. It takes control of the brain’s reward system, erasing the shininess from substances that have us wanting more and more.
Let’s think of our favorite food. If all of a sudden, it didn’t taste good to us anymore, we probably wouldn’t want to eat it again. Naltrexone works in this way, blocking the positive feelings we previously associated with drinking alcohol — helping to eliminate dependence.
The medication comes in two different forms. Both the pill form and the extended-release injectable (Vivitrol) are typically prescribed as just one component of an extensive treatment plan for substance use disorders. The pill is less common; it’s prescribed and taken at home. The injectable is administered by a clinician and is a common part of outpatient treatment programs.
Naltrexone has been a staple of recovery programs since the 1980s. In 2002, a new player entered the market: Suboxone. How are naltrexone and Suboxone different? To understand that, let’s get a clearer picture of what Suboxone is.
Suboxone is a medication composed of a combination of two drugs — buprenorphine and naloxone. The four-to-one ratio of buprenorphine and naloxone make up Suboxone, an FDA-approved medication primarily used to treat OUD. The combination of the two drugs gives Suboxone its unique action mechanism that decreases substance dependence.
Buprenorphine is categorized as an opioid partial agonist, meaning it has some opiate properties. This means that it stimulates similar feelings produced by opioids at a much lower dose. Naloxone (the generic name for Narcan) is a strong opioid antagonist, just like naltrexone. It prevents the activation of opioid receptors, blocking the rewarding part of our reward system. In combination, these drugs are effective in treating OUD by reducing cravings and withdrawal symptoms at the same time.
Naltrexone and Suboxone can be likened to the difference between Tylenol and Advil, two different medications used to treat similar symptoms. Despite their differences, the two are often associated. Let’s take a closer look at why this is.
To understand why naltrexone and Suboxone are frequently associated with one another, let’s take a look at three big ways they’re linked.
Clearly, these two medications are associated for a reason. But the truth is, they’re quite different.
Naltrexone and Suboxone are both FDA-approved medications, but their distinguishable differences help us determine whether or not they can be used in conjunction. The three differences between Suboxone and naltrexone are based on these main aspects:
We’ve acknowledged the distinct differences between naltrexone and Suboxone, but let’s dive further to see if they can be used together.
To put it bluntly — no. Naltrexone and Suboxone should not be taken together in any situation.
The two drugs have interactions that cancel out their effects. Naltrexone is an opioid antagonist that attaches to receptors in our brain and blocks intoxicating effects. Since buprenorphine, the main component of Suboxone, is a partial opioid agonist, naltrexone will not allow it to attach — making the entire mechanism of Suboxone ineffective.
Think of a plug and socket. Naltrexone is the plastic cover that covers the socket to keep it protected. Suboxone is the plug that goes into the socket. There’s no way to plug both in at the same time, just like naltrexone and Suboxone can’t be used together.
Not only do they block each other’s effects, but naltrexone and Suboxone if used together cause some potentially harmful results.
Side effects are a part of all medications, but the mix of naltrexone and Suboxone causes additional complications. One of the main consequences of taking naltrexone and Suboxone together is the occurrence of precipitated withdrawal.
Precipitated withdrawal is the immediate and severe onset of withdrawal symptoms. Let’s go back to our plug-and-socket analogy. If we were to force the plastic cover (naltrexone) and the plug (Suboxone) into the socket at the same time, it would break and potentially cause a shock — just the way the mixed signals in our brain can cause precipitated withdrawal. Precipitated withdrawal involves potentially dangerous manifestations that are not limited to these symptoms:
Naltrexone and Suboxone each have individual side effects that should be taken into account. Taking the two medications together can not only cause a sudden onset of withdrawal, but it can also compound secondary repercussions. We are at risk of experiencing a greater number of common side effects that may involve the following:
While taking naltrexone and Suboxone together isn’t an option, let’s explore some ways that we can navigate recovery to make the journey less brutal.
Recovery from AUD is no picnic in the park, but we can utilize strategies to make it easier. Let’s delve into some ways to better navigate recovery and withdrawal.
Withdrawal symptoms are a common but unpleasant experience in recovery. Alleviating unpleasant withdrawal symptoms is a significant aspect of preventing relapse. Serious withdrawal symptoms of AWS such as delirium tremens require medical attention and can be life-threatening to bear alone. We can manage less severe experiences of withdrawal by taking the following steps:
It can be challenging to move forward and away from the limited world of drinking after living with alcohol dependence. Thankfully, there is so much more to life! We can start thriving by focusing our energy toward the following positive practices:
Naltrexone and Suboxone are often discussed in the same breath (their names are even similar!), but they are incredibly different. While both are used to treat substance misuse, they differ greatly in the way they work. It’s important to be aware of the impacts of mixing the two to prevent dangerous consequences. We’re commonly looking for ways to add to our life. But, the combination of naltrexone and Suboxone is one we want to divide!
Ever heard of the saying “the more the merrier”? While this may be true for laughter and love, the same can’t be said for naltrexone and Suboxone. Naltrexone and Suboxone are two common medications used to treat substance use disorders and can commonly be mistaken as one and the same.
Recovering from substance dependence is no cakewalk, and unpleasant withdrawal symptoms may have us wondering if taking both naltrexone and Suboxone can help. This strategy may have worked that time we needed an extra Tylenol for that unusually unbearable headache, but with naltrexone and Suboxone, double dipping can cause detrimental effects.
For those of us who are recovering from substance dependence, it’s worth exploring all possible solutions to help us reach our end goal. Having better knowledge of what naltrexone and Suboxone are and how they work helps us understand why they don’t go hand-in-hand. Let’s get into some alternative strategies for how to navigate substance use recovery, but first, let’s understand more about the combination of naltrexone and Suboxone to help cross it off the list for possible solutions.
Naltrexone is a type of drug known as an opioid antagonist, meaning it blocks the action of opioids. It’s approved by the Food and Drug Administration (FDA) as a medication to treat alcohol use disorder (AUD) and opioid use disorder (OUD). Naltrexone works by blocking opioid receptors in our brain — effectively getting rid of the intoxication effects of alcohol and opioids. It takes control of the brain’s reward system, erasing the shininess from substances that have us wanting more and more.
Let’s think of our favorite food. If all of a sudden, it didn’t taste good to us anymore, we probably wouldn’t want to eat it again. Naltrexone works in this way, blocking the positive feelings we previously associated with drinking alcohol — helping to eliminate dependence.
The medication comes in two different forms. Both the pill form and the extended-release injectable (Vivitrol) are typically prescribed as just one component of an extensive treatment plan for substance use disorders. The pill is less common; it’s prescribed and taken at home. The injectable is administered by a clinician and is a common part of outpatient treatment programs.
Naltrexone has been a staple of recovery programs since the 1980s. In 2002, a new player entered the market: Suboxone. How are naltrexone and Suboxone different? To understand that, let’s get a clearer picture of what Suboxone is.
Suboxone is a medication composed of a combination of two drugs — buprenorphine and naloxone. The four-to-one ratio of buprenorphine and naloxone make up Suboxone, an FDA-approved medication primarily used to treat OUD. The combination of the two drugs gives Suboxone its unique action mechanism that decreases substance dependence.
Buprenorphine is categorized as an opioid partial agonist, meaning it has some opiate properties. This means that it stimulates similar feelings produced by opioids at a much lower dose. Naloxone (the generic name for Narcan) is a strong opioid antagonist, just like naltrexone. It prevents the activation of opioid receptors, blocking the rewarding part of our reward system. In combination, these drugs are effective in treating OUD by reducing cravings and withdrawal symptoms at the same time.
Naltrexone and Suboxone can be likened to the difference between Tylenol and Advil, two different medications used to treat similar symptoms. Despite their differences, the two are often associated. Let’s take a closer look at why this is.
To understand why naltrexone and Suboxone are frequently associated with one another, let’s take a look at three big ways they’re linked.
Clearly, these two medications are associated for a reason. But the truth is, they’re quite different.
Naltrexone and Suboxone are both FDA-approved medications, but their distinguishable differences help us determine whether or not they can be used in conjunction. The three differences between Suboxone and naltrexone are based on these main aspects:
We’ve acknowledged the distinct differences between naltrexone and Suboxone, but let’s dive further to see if they can be used together.
To put it bluntly — no. Naltrexone and Suboxone should not be taken together in any situation.
The two drugs have interactions that cancel out their effects. Naltrexone is an opioid antagonist that attaches to receptors in our brain and blocks intoxicating effects. Since buprenorphine, the main component of Suboxone, is a partial opioid agonist, naltrexone will not allow it to attach — making the entire mechanism of Suboxone ineffective.
Think of a plug and socket. Naltrexone is the plastic cover that covers the socket to keep it protected. Suboxone is the plug that goes into the socket. There’s no way to plug both in at the same time, just like naltrexone and Suboxone can’t be used together.
Not only do they block each other’s effects, but naltrexone and Suboxone if used together cause some potentially harmful results.
Side effects are a part of all medications, but the mix of naltrexone and Suboxone causes additional complications. One of the main consequences of taking naltrexone and Suboxone together is the occurrence of precipitated withdrawal.
Precipitated withdrawal is the immediate and severe onset of withdrawal symptoms. Let’s go back to our plug-and-socket analogy. If we were to force the plastic cover (naltrexone) and the plug (Suboxone) into the socket at the same time, it would break and potentially cause a shock — just the way the mixed signals in our brain can cause precipitated withdrawal. Precipitated withdrawal involves potentially dangerous manifestations that are not limited to these symptoms:
Naltrexone and Suboxone each have individual side effects that should be taken into account. Taking the two medications together can not only cause a sudden onset of withdrawal, but it can also compound secondary repercussions. We are at risk of experiencing a greater number of common side effects that may involve the following:
While taking naltrexone and Suboxone together isn’t an option, let’s explore some ways that we can navigate recovery to make the journey less brutal.
Recovery from AUD is no picnic in the park, but we can utilize strategies to make it easier. Let’s delve into some ways to better navigate recovery and withdrawal.
Withdrawal symptoms are a common but unpleasant experience in recovery. Alleviating unpleasant withdrawal symptoms is a significant aspect of preventing relapse. Serious withdrawal symptoms of AWS such as delirium tremens require medical attention and can be life-threatening to bear alone. We can manage less severe experiences of withdrawal by taking the following steps:
It can be challenging to move forward and away from the limited world of drinking after living with alcohol dependence. Thankfully, there is so much more to life! We can start thriving by focusing our energy toward the following positive practices:
Naltrexone and Suboxone are often discussed in the same breath (their names are even similar!), but they are incredibly different. While both are used to treat substance misuse, they differ greatly in the way they work. It’s important to be aware of the impacts of mixing the two to prevent dangerous consequences. We’re commonly looking for ways to add to our life. But, the combination of naltrexone and Suboxone is one we want to divide!
Drinking on Xtandi leads to negative effects despite no direct interactions. Check out our latest blog for more info on how alcohol adds fuel to the fire of Xtandi’s side effects.
Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!
The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.
You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.
Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol.
And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).
The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!
Prostate cancer affects a shocking 13% of men, but luckily it has a high successful treatment rate. Common treatments include active monitoring, radiation therapy, surgery, and hormone therapy. However, these treatments aren’t always effective. When prostate cancer progresses toward more advanced stages and nothing seems to be working, that’s when Xtandi can come in handy.
Xtandi is an effective treatment for high-risk prostate cancer, but it can interact with many other drugs and substances. Avoiding these interactions can be a bit like walking through a minefield — trying hard not to trigger a reaction. Let’s better understand Xtandi’s interactions to clear a path for safe consumption.
Xtandi is a prescription medication that’s used to treat certain types of advanced prostate cancer. It’s approved for two types of prostate cancer:
Xtandi contains the drug enzalutamide, which belongs to a class of drugs called androgen receptor inhibitors. These drugs prevent the cancer from spreading by blocking the effects of androgens (male hormones). Those who are prescribed Xtandi should have already completed surgery to remove the testicles (orchiectomy), or have been taking another drug that lowers testosterone levels for full effectiveness of Xtandi.
Clinical studies showed that in men with metastatic prostate cancer that no longer improved with medication or surgery, Xtandi (or enzalutamide) led to a 71% lower risk of the cancer spreading. In a group of men with nonmetastatic prostate cancer, Xtandi had an 83% lower risk of the cancer worsening in comparison to a group taking a placebo. Although Xtandi is an effective medication, it’s associated with potential side effects.
Xtandi can cause a range of mild to severe side effects. Common side effects include:
If these mild side effects worsen or don’t subside after a few weeks, talk to your doctor. Serious side effects are less common but can occur:
If you’re experiencing any severe side effects, call 9-1-1 for emergency medical attention. Xtandi is already associated with many side effects, but when we add alcohol to the equation, things can get even more serious.
Xtandi, like all medications, is associated with side effects. However, mixing Xtandi and alcohol can be a whole different ball game.
In short, alcohol adds fuel to the risks of Xtandi. Mixing the two could lead to double the trouble. Here’s why:
Alcohol and Xtandi have many overlapping side effects:
As we can see, alcohol adds fuel to the fire — worsening side effects. But there’s even more to consider!
Both Xtandi and alcohol are processed by the liver. When we drink, our liver prioritizes getting rid of the toxins from alcohol (for good reason). However, since our liver is in overdrive with having to deal with more than one thing at a time, it gives the toxins more time to linger. This can lead to increased side effects and hangover symptoms.
Putting our liver into overdrive not only leads to negative short-term effects, but also causes long-term liver damage. Over time, constant stress can lead to liver dysfunction and disease. To learn more about how quickly this can happen, check out “How Much Alcohol Causes Liver Damage?”
Xtandi works by blocking the action of male hormones. This slows prostate cancer growth and promotes cancer cell death. Alcohol, on the other hand, imbalances our hormones, disrupting the mechanism of Xtandi.
In small amounts, alcohol can increase the production of testosterone (a type of androgen). Over time however, alcohol has the opposite effect on testosterone. While this may sound like it works in our favor (for the sake of inhibiting androgens to treat prostate cancer), fluctuations in our testosterone only lead to greater hormonal imbalance. In fact, research shows that hormonal imbalance is one of the causes of prostate cancer. Want to learn more about alcohol’s effects on our hormones? Check out “How Does Quitting Alcohol Help Your Hormones?”
Another risk of mixing Xtandi and alcohol? Poor mental health. While Xtandi alone isn’t associated with mental health issues, prostate cancer is. Significant mental health problems such as depression, anxiety, fear of cancer recurrence, and self-esteem issues are prevalent among those diagnosed with prostate cancer.
Similarly, alcohol is also associated with a host of mental health issues. Alcohol hijacks chemical messengers (neurotransmitters in our brain) that influence our mood. While we may feel a temporary boost in mood when we’re drinking, the depressant aftereffects increase the risk of mental health conditions such as anxiety, depression, and mood disorders. To get a more in-depth look at alcohol’s psychological impacts, take a look at “Understanding Alcohol’s Effects on Mental Health.”
Lastly, Xtandi and alcohol both interact with many other substances. Xtandi is commonly used in conjunction with other treatments to help attack prostate cancer on all fronts. For example, high-energy radiation used to destroy cancer cells (radiation therapy) is often used with Xtandi. Physicians recommend avoiding alcohol during radiation therapy, as it can make the experience even more unpleasant. Recovery from prostate cancer can include much more than Xtandi, increasing the chances of negative interactions when we choose to drink.
To make matters more complicated, alcohol affects our inhibitions and judgment. Recall the long list of interactions printed on the warning label of Xtandi? Or the reminder from the doctor not to mix certain medications with alcohol? Well, alcohol can make these directions a bit fuzzy in our minds — and as a result, we may end up mixing substances that have dangerous interactions. What else should we take into consideration when taking Xtandi?
In addition to clashing with alcohol, Xtandi interacts with many other medications. Let’s get a better idea of what they are and how alcohol further complicates things.
Buspirone is a medication used to treat anxiety disorders by balancing the hormones that control our mood. Xtandi speeds up the breakdown of buspirone, leading to lower levels of the medication in our body — and as a result, decreases the effectiveness of buspirone.
Alcohol and buspirone are also not a good mix. Since there aren’t any direct interactions, you may be wondering, “Can you drink while taking buspirone?” The short answer is no. Mixing alcohol with buspirone can lead to worsened side effects such as dizziness, drowsiness, difficulty breathing, and confusion. Additionally, alcohol negatively impacts anxiety, indirectly impacting buspirone. In short, alcohol, buspirone, and Xtandi are an incompatible combination.
Benzodiazepines are a class of depressant drugs used to treat anxiety, seizures, and other conditions. They work by slowing down activity in our brain and nervous system. Xtandi decreases levels of the benzodiazepines in our body, making them less effective and increasing the risk of benzodiazepine withdrawal.
Do the depressant effects of benzodiazepines sound familiar? That’s because alcohol is also a depressant that causes similar effects on our central nervous system (CNS). Mixing the alcohol and benzodiazepines amplifies their dangers including exacerbated side effects, increased risk of overdose, and increased risk of dependence.
This class of drugs reduces anxiety and induces calming effects, which is helpful in treating insomnia or other sleep disorders. Xtandi impacts the effectiveness of sedative-hypnotics, as it promotes speedier breakdown of the drugs.
Mixing alcohol and sedative-hypnotics is also a bad idea. Like benzodiazepines, sedative-hypnotics are also CNS depressants that act on the same system as alcohol. Drinking while taking sedative-hypnotics increases their depressant effects, risk of overdose, and risk of dependence.
Before starting Xtandi, it’s important to discuss with our physician which prescription medications, over-the-counter medications, and other substances we’re taking. Aside from the more obvious prescription medications, let’s see what else we need to make note of.
Aside from prescription medications, Xtandi doesn’t mix well with several other substances:
To stay on the safe side, we should consult with our doctor if we’re taking or planning to take any of these substances.
The average half-life of Xtandi is 5.8 days or 6 to be safe. However, it takes about 5 half-lives for a medication to be completely eliminated from our system. It’s recommended to wait at least 30 days after stopping Xtandi to avoid the potential risks of mixing Xtandi and alcohol.
Waiting for the elimination period to pass before drinking is helpful in reducing indirect interactions between Xtandi and alcohol, but it’s important to note that drinking is still detrimental to our health. In regards to recovering from prostate cancer, alcohol imbalances our hormones and puts a damper on immune function — leading to an increased risk of cancer recurrence and impacted recovery. Let’s explore some ways we can approach Xtandi and alcohol more safely and mindfully.
Understanding Xtandi and alcohol’s interactions is one way we can prioritize our safety. Implementing mindful consumption strategies can further promote our health and safety:
Navigating prostate cancer and alcohol is no easy task. But remember that Reframe is here for you as you work towards a happier and healthier life. Be a part of our thriving community and connect with others who may share similar struggles. We can work together to support each other every step of the way!
Xtandi is an effective treatment for advanced prostate cancer, but navigating it safely can be a bit of a balancing act. It has interactions with other medications and substances, including alcohol. Drinking while taking Xtandi amplifies its side effects and opens the door to other potential risks. Luckily, we can minimize these risks by quitting or cutting back on alcohol. Exact the full effectiveness of Xtandi by avoiding interactions!
Prostate cancer affects a shocking 13% of men, but luckily it has a high successful treatment rate. Common treatments include active monitoring, radiation therapy, surgery, and hormone therapy. However, these treatments aren’t always effective. When prostate cancer progresses toward more advanced stages and nothing seems to be working, that’s when Xtandi can come in handy.
Xtandi is an effective treatment for high-risk prostate cancer, but it can interact with many other drugs and substances. Avoiding these interactions can be a bit like walking through a minefield — trying hard not to trigger a reaction. Let’s better understand Xtandi’s interactions to clear a path for safe consumption.
Xtandi is a prescription medication that’s used to treat certain types of advanced prostate cancer. It’s approved for two types of prostate cancer:
Xtandi contains the drug enzalutamide, which belongs to a class of drugs called androgen receptor inhibitors. These drugs prevent the cancer from spreading by blocking the effects of androgens (male hormones). Those who are prescribed Xtandi should have already completed surgery to remove the testicles (orchiectomy), or have been taking another drug that lowers testosterone levels for full effectiveness of Xtandi.
Clinical studies showed that in men with metastatic prostate cancer that no longer improved with medication or surgery, Xtandi (or enzalutamide) led to a 71% lower risk of the cancer spreading. In a group of men with nonmetastatic prostate cancer, Xtandi had an 83% lower risk of the cancer worsening in comparison to a group taking a placebo. Although Xtandi is an effective medication, it’s associated with potential side effects.
Xtandi can cause a range of mild to severe side effects. Common side effects include:
If these mild side effects worsen or don’t subside after a few weeks, talk to your doctor. Serious side effects are less common but can occur:
If you’re experiencing any severe side effects, call 9-1-1 for emergency medical attention. Xtandi is already associated with many side effects, but when we add alcohol to the equation, things can get even more serious.
Xtandi, like all medications, is associated with side effects. However, mixing Xtandi and alcohol can be a whole different ball game.
In short, alcohol adds fuel to the risks of Xtandi. Mixing the two could lead to double the trouble. Here’s why:
Alcohol and Xtandi have many overlapping side effects:
As we can see, alcohol adds fuel to the fire — worsening side effects. But there’s even more to consider!
Both Xtandi and alcohol are processed by the liver. When we drink, our liver prioritizes getting rid of the toxins from alcohol (for good reason). However, since our liver is in overdrive with having to deal with more than one thing at a time, it gives the toxins more time to linger. This can lead to increased side effects and hangover symptoms.
Putting our liver into overdrive not only leads to negative short-term effects, but also causes long-term liver damage. Over time, constant stress can lead to liver dysfunction and disease. To learn more about how quickly this can happen, check out “How Much Alcohol Causes Liver Damage?”
Xtandi works by blocking the action of male hormones. This slows prostate cancer growth and promotes cancer cell death. Alcohol, on the other hand, imbalances our hormones, disrupting the mechanism of Xtandi.
In small amounts, alcohol can increase the production of testosterone (a type of androgen). Over time however, alcohol has the opposite effect on testosterone. While this may sound like it works in our favor (for the sake of inhibiting androgens to treat prostate cancer), fluctuations in our testosterone only lead to greater hormonal imbalance. In fact, research shows that hormonal imbalance is one of the causes of prostate cancer. Want to learn more about alcohol’s effects on our hormones? Check out “How Does Quitting Alcohol Help Your Hormones?”
Another risk of mixing Xtandi and alcohol? Poor mental health. While Xtandi alone isn’t associated with mental health issues, prostate cancer is. Significant mental health problems such as depression, anxiety, fear of cancer recurrence, and self-esteem issues are prevalent among those diagnosed with prostate cancer.
Similarly, alcohol is also associated with a host of mental health issues. Alcohol hijacks chemical messengers (neurotransmitters in our brain) that influence our mood. While we may feel a temporary boost in mood when we’re drinking, the depressant aftereffects increase the risk of mental health conditions such as anxiety, depression, and mood disorders. To get a more in-depth look at alcohol’s psychological impacts, take a look at “Understanding Alcohol’s Effects on Mental Health.”
Lastly, Xtandi and alcohol both interact with many other substances. Xtandi is commonly used in conjunction with other treatments to help attack prostate cancer on all fronts. For example, high-energy radiation used to destroy cancer cells (radiation therapy) is often used with Xtandi. Physicians recommend avoiding alcohol during radiation therapy, as it can make the experience even more unpleasant. Recovery from prostate cancer can include much more than Xtandi, increasing the chances of negative interactions when we choose to drink.
To make matters more complicated, alcohol affects our inhibitions and judgment. Recall the long list of interactions printed on the warning label of Xtandi? Or the reminder from the doctor not to mix certain medications with alcohol? Well, alcohol can make these directions a bit fuzzy in our minds — and as a result, we may end up mixing substances that have dangerous interactions. What else should we take into consideration when taking Xtandi?
In addition to clashing with alcohol, Xtandi interacts with many other medications. Let’s get a better idea of what they are and how alcohol further complicates things.
Buspirone is a medication used to treat anxiety disorders by balancing the hormones that control our mood. Xtandi speeds up the breakdown of buspirone, leading to lower levels of the medication in our body — and as a result, decreases the effectiveness of buspirone.
Alcohol and buspirone are also not a good mix. Since there aren’t any direct interactions, you may be wondering, “Can you drink while taking buspirone?” The short answer is no. Mixing alcohol with buspirone can lead to worsened side effects such as dizziness, drowsiness, difficulty breathing, and confusion. Additionally, alcohol negatively impacts anxiety, indirectly impacting buspirone. In short, alcohol, buspirone, and Xtandi are an incompatible combination.
Benzodiazepines are a class of depressant drugs used to treat anxiety, seizures, and other conditions. They work by slowing down activity in our brain and nervous system. Xtandi decreases levels of the benzodiazepines in our body, making them less effective and increasing the risk of benzodiazepine withdrawal.
Do the depressant effects of benzodiazepines sound familiar? That’s because alcohol is also a depressant that causes similar effects on our central nervous system (CNS). Mixing the alcohol and benzodiazepines amplifies their dangers including exacerbated side effects, increased risk of overdose, and increased risk of dependence.
This class of drugs reduces anxiety and induces calming effects, which is helpful in treating insomnia or other sleep disorders. Xtandi impacts the effectiveness of sedative-hypnotics, as it promotes speedier breakdown of the drugs.
Mixing alcohol and sedative-hypnotics is also a bad idea. Like benzodiazepines, sedative-hypnotics are also CNS depressants that act on the same system as alcohol. Drinking while taking sedative-hypnotics increases their depressant effects, risk of overdose, and risk of dependence.
Before starting Xtandi, it’s important to discuss with our physician which prescription medications, over-the-counter medications, and other substances we’re taking. Aside from the more obvious prescription medications, let’s see what else we need to make note of.
Aside from prescription medications, Xtandi doesn’t mix well with several other substances:
To stay on the safe side, we should consult with our doctor if we’re taking or planning to take any of these substances.
The average half-life of Xtandi is 5.8 days or 6 to be safe. However, it takes about 5 half-lives for a medication to be completely eliminated from our system. It’s recommended to wait at least 30 days after stopping Xtandi to avoid the potential risks of mixing Xtandi and alcohol.
Waiting for the elimination period to pass before drinking is helpful in reducing indirect interactions between Xtandi and alcohol, but it’s important to note that drinking is still detrimental to our health. In regards to recovering from prostate cancer, alcohol imbalances our hormones and puts a damper on immune function — leading to an increased risk of cancer recurrence and impacted recovery. Let’s explore some ways we can approach Xtandi and alcohol more safely and mindfully.
Understanding Xtandi and alcohol’s interactions is one way we can prioritize our safety. Implementing mindful consumption strategies can further promote our health and safety:
Navigating prostate cancer and alcohol is no easy task. But remember that Reframe is here for you as you work towards a happier and healthier life. Be a part of our thriving community and connect with others who may share similar struggles. We can work together to support each other every step of the way!
Xtandi is an effective treatment for advanced prostate cancer, but navigating it safely can be a bit of a balancing act. It has interactions with other medications and substances, including alcohol. Drinking while taking Xtandi amplifies its side effects and opens the door to other potential risks. Luckily, we can minimize these risks by quitting or cutting back on alcohol. Exact the full effectiveness of Xtandi by avoiding interactions!
These days, there are plenty of options when it comes to medication to stop drinking, alcohol craving medication, and meds that help with withdrawal. Learn all about them in our latest blog!
Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!
The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.
You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.
Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol.
And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).
The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!
When we find ourselves in a tricky situation, it’s natural to wish for a magic pill to make it go away. And alcohol misuse is, certainly, a tricky situation (to say the least). It can feel nearly impossible to stop drinking once the habit takes hold, and you might find yourself wondering, “If only there were a pill to stop drinking!”
If you’re facing this problem, first of all, know that you’re not alone. And if you’re wondering how to stop alcohol cravings or if there’s a medication to stop drinking, you’re in luck — there are several! Let’s explore the pros and cons of each to help you decide if one is right for you, based on your needs and goals around alcohol.
First things first: what exactly are we dealing with? Alcohol use disorder (AUD) is a progressive mental health condition marked by an inability to stop excessive drinking. According to the National Institute on Alcohol Abuse and Alcoholism (NIAAA), in the U.S. as many as 29.5 million people ages 12 and older are struggling with AUD. That’s more than 10% of everyone in this age group!
While it might puzzle a nondrinker who has never dealt with alcoholism (“Why can’t they just stop?”), there’s brain chemistry behind the condition and its often devastating effects. For an in-depth look at AUD, check out our blog “What Is Alcohol Use Disorder?” For now, here’s the gist of it:
Needless to say, once we’re at the stage of dependence, getting out of the alcohol trap can seem all but impossible. But rest assured, there’s a way out!
This is where medications come in (at least for some of us). There are three main approaches to treating AUD with medications: making alcohol less effective, making it intolerable, or making it less desirable. Let’s explore each one in more detail.
Why is drinking so habit-forming to begin with? As we know, it’s all about brain chemistry. Let’s face it: without that dopamine rush, fewer people would probably be guzzling down a liquid that doesn’t always taste great on its own (there’s a reason it’s called an “acquired taste”).
Medications that interfere with the rewarding effects associated with drinking take out the pleasure factor, making it easier to stay away from booze. After all, with the main reason to drink out of the picture, what’s the point?
Naltrexone was originally developed to treat opioid addiction, but has been gaining traction as an effective treatment for AUD. Chemically similar to opioids but without the same euphoric effects, it works by blocking opioid receptors in the brain. Because these receptors are part of the brain’s reward system activated by alcohol, blocking them reduces the pleasure we get from drinking.
Imagine you’re waiting for a fun package (a chocolate wafer cake, a new yoga outfit — whatever tickles your fancy), but your mailbox is so full of junk mail that nothing else can fit. The postal worker ends up taking your package back to the post office and you’re left with a pile of mail that’s neither good nor bad — it’s just taking up space. Well, that’s what naltrexone does to our brain! (For a deep dive, check out “Unlocking the Science: How Long Does Naltrexone Block Alcohol?”)
Pros:
Cons:
A chemical counterpart of naltrexone, nalmefene is an opioid antagonist. Instead of acting as an opioid by binding to opioid receptors, it blocks the receptors completely — breaking the metaphorical mailbox lock and making it impossible to open at all. The result, however, is the same — we don’t get the reward associated with drinking.
Pros:
Cons:
A more drastic way to treat AUD with medications involves making booze highly unpleasant instead of merely neutral. Sure, this one’s not for the faint of heart (and is only right for those committed to leaving alcohol behind for good). Still, many have found that taking a medication that induces alcohol intolerance is actually an effective way to get back in the driver’s seat when it comes to making daily decisions. Took your meds in the morning? You know booze is out of the question tonight — no need for the time-consuming and exhausting mental back-and-forth throughout the day.
The story of disulfiram (known by the brand name Antabuse) began — of all places — in a rubber plant. At the turn of the 20th century, it was used in the industrial process of rubber production. A couple of decades later, some workers at a Swedish rubber boot factory (along with their American counterparts) noticed a curious trend: for those exposed to the chemical on a regular basis, “happy hour” wasn’t quite so happy anymore. When mixed with alcohol, disulfiram seemed to induce flushing, nausea, and palpitations — symptoms similar to those of alcohol intolerance.
While the workers at the rubber factory probably found this to be a buzzkill, the properties of disulfiram eventually proved to be useful in treating AUD. As it turned out, it throws a wrench in the metabolism of alcohol, leading to a build-up of a toxic by-product, acetaldehyde. While acetaldehyde is normally converted into harmless acetate by the liver, disulfiram makes it stick around, leading to symptoms that are (to put it mildly) highly unpleasant. (For more information, check out our blog “How Does Disulfiram Work?”.)
Pros:
Cons:
Similar in action to disulfiram, calcium carbimide also interferes with alcohol metabolism. If we drink on this medication, we’ll experience unpleasant effects that act as a deterrent to drinking.
Pros:
Cons:
Now, let’s step back a bit. We talked about why alcohol loses its “magic” if we’re taking naltrexone or nalmefene. But think about what happens before we drink, before we take disulfiram to ward off the temptation to pour it in the first place. The answer is, a thought — “I want a drink” — enters our head. That thought is often referred to as an urge or a craving — and many believe that it’s the very root of addiction.
What do cravings feel like? It depends on the person, but when it comes to substance use, cravings are desires for something we wish we didn’t want (now that’s mind-bending, isn’t it?). By eliminating the craving, which is the result of brain chemistry conditioned by habitual alcohol use, we eliminate the “need” we feel to have that drink.
It’s important to understand that cravings are not “true” desires, and that as far as habits are concerned, “wanting” isn’t the same as “liking.” Dopamine makes us feel like we want things we don’t necessarily enjoy — that’s why we can feel the compulsion to keep drinking in spite of the fact that alcohol isn’t providing authentic enjoyment. At a certain point, if we’ve become dependent, even the illusion of pleasure disappears, while the craving only seems to grow stronger.
Medications that target cravings, in turn, help us interrupt the vicious cycle from the get-go. The result? We don’t have to pour that drink, taste it, and find it unsatisfying. We don’t have to safeguard ourselves from having it by taking medications that could send us to the emergency room if we mix them with booze. In fact, alcohol might not even cross our mind at all!
For those who are committed to being booze-free, Campral has been a popular option. One important caveat: it works over time and is meant for those who’ve left alcohol behind and are trying to stay away from it for good.
Pros:
Cons:
Topiramate, in turn, targets cravings by decreasing the dopamine release associated with alcohol use. The result? Just like the first category of drugs, Topamax makes booze lose its appeal. However, because the effect is indirect (we’re talking about the reward system as opposed to opioid receptors), it affects our desire for alcohol and — like Campral — lives in the realm of cravings.
Pros:
Cons:
Gabapentin is beneficial for managing withdrawal symptoms and reducing alcohol cravings. Developed as an antiseizure medication, it helps stabilize the brain’s electrical activity and has been shown to be effective in treating alcohol dependence.
Pros:
Cons:
Now that we’re familiar with the meds out there that can help us stop drinking or reduce our cravings, what do we do with this information? Here are some questions to consider as you decide if any one of these treatments might be the right course for you.
First and foremost, the answer depends on your goals. Those who want to quit completely and are committed to staying booze-free will have different needs from those who simply want alcohol to be less prominent in their lives.
And remember what we said about decision fatigue? Science says we make about 35,000 decisions a day. Needless to say, our brain gets tired from the constant back-and-forth.
When we throw medications for AUD into the mix, the number of daily decisions is a factor to keep in mind. Remember, we’re talking about the decision to take the medication as well as the decision whether or not to drink.
Finally, overall health is also an important factor. All medications have side effects, and those that help with AUD recovery are no exception. Plus, some of us may have additional needs that we’re trying to address with medications.
Finally, it’s important to keep in mind that if it turns out medication isn’t the right route for you, there are plenty of ways to stop drinking without it! For a deep dive, check out “How Easy Is It To Quit Drinking in 2024?” For now, here are some tips to start with:
And remember, no matter which approach you choose, it’s essential to have a support system behind you. If you’re looking for a community of like-minded people who’ve been where you are and are now thriving, the Reframe forum is a great place to start!
When we find ourselves in a tricky situation, it’s natural to wish for a magic pill to make it go away. And alcohol misuse is, certainly, a tricky situation (to say the least). It can feel nearly impossible to stop drinking once the habit takes hold, and you might find yourself wondering, “If only there were a pill to stop drinking!”
If you’re facing this problem, first of all, know that you’re not alone. And if you’re wondering how to stop alcohol cravings or if there’s a medication to stop drinking, you’re in luck — there are several! Let’s explore the pros and cons of each to help you decide if one is right for you, based on your needs and goals around alcohol.
First things first: what exactly are we dealing with? Alcohol use disorder (AUD) is a progressive mental health condition marked by an inability to stop excessive drinking. According to the National Institute on Alcohol Abuse and Alcoholism (NIAAA), in the U.S. as many as 29.5 million people ages 12 and older are struggling with AUD. That’s more than 10% of everyone in this age group!
While it might puzzle a nondrinker who has never dealt with alcoholism (“Why can’t they just stop?”), there’s brain chemistry behind the condition and its often devastating effects. For an in-depth look at AUD, check out our blog “What Is Alcohol Use Disorder?” For now, here’s the gist of it:
Needless to say, once we’re at the stage of dependence, getting out of the alcohol trap can seem all but impossible. But rest assured, there’s a way out!
This is where medications come in (at least for some of us). There are three main approaches to treating AUD with medications: making alcohol less effective, making it intolerable, or making it less desirable. Let’s explore each one in more detail.
Why is drinking so habit-forming to begin with? As we know, it’s all about brain chemistry. Let’s face it: without that dopamine rush, fewer people would probably be guzzling down a liquid that doesn’t always taste great on its own (there’s a reason it’s called an “acquired taste”).
Medications that interfere with the rewarding effects associated with drinking take out the pleasure factor, making it easier to stay away from booze. After all, with the main reason to drink out of the picture, what’s the point?
Naltrexone was originally developed to treat opioid addiction, but has been gaining traction as an effective treatment for AUD. Chemically similar to opioids but without the same euphoric effects, it works by blocking opioid receptors in the brain. Because these receptors are part of the brain’s reward system activated by alcohol, blocking them reduces the pleasure we get from drinking.
Imagine you’re waiting for a fun package (a chocolate wafer cake, a new yoga outfit — whatever tickles your fancy), but your mailbox is so full of junk mail that nothing else can fit. The postal worker ends up taking your package back to the post office and you’re left with a pile of mail that’s neither good nor bad — it’s just taking up space. Well, that’s what naltrexone does to our brain! (For a deep dive, check out “Unlocking the Science: How Long Does Naltrexone Block Alcohol?”)
Pros:
Cons:
A chemical counterpart of naltrexone, nalmefene is an opioid antagonist. Instead of acting as an opioid by binding to opioid receptors, it blocks the receptors completely — breaking the metaphorical mailbox lock and making it impossible to open at all. The result, however, is the same — we don’t get the reward associated with drinking.
Pros:
Cons:
A more drastic way to treat AUD with medications involves making booze highly unpleasant instead of merely neutral. Sure, this one’s not for the faint of heart (and is only right for those committed to leaving alcohol behind for good). Still, many have found that taking a medication that induces alcohol intolerance is actually an effective way to get back in the driver’s seat when it comes to making daily decisions. Took your meds in the morning? You know booze is out of the question tonight — no need for the time-consuming and exhausting mental back-and-forth throughout the day.
The story of disulfiram (known by the brand name Antabuse) began — of all places — in a rubber plant. At the turn of the 20th century, it was used in the industrial process of rubber production. A couple of decades later, some workers at a Swedish rubber boot factory (along with their American counterparts) noticed a curious trend: for those exposed to the chemical on a regular basis, “happy hour” wasn’t quite so happy anymore. When mixed with alcohol, disulfiram seemed to induce flushing, nausea, and palpitations — symptoms similar to those of alcohol intolerance.
While the workers at the rubber factory probably found this to be a buzzkill, the properties of disulfiram eventually proved to be useful in treating AUD. As it turned out, it throws a wrench in the metabolism of alcohol, leading to a build-up of a toxic by-product, acetaldehyde. While acetaldehyde is normally converted into harmless acetate by the liver, disulfiram makes it stick around, leading to symptoms that are (to put it mildly) highly unpleasant. (For more information, check out our blog “How Does Disulfiram Work?”.)
Pros:
Cons:
Similar in action to disulfiram, calcium carbimide also interferes with alcohol metabolism. If we drink on this medication, we’ll experience unpleasant effects that act as a deterrent to drinking.
Pros:
Cons:
Now, let’s step back a bit. We talked about why alcohol loses its “magic” if we’re taking naltrexone or nalmefene. But think about what happens before we drink, before we take disulfiram to ward off the temptation to pour it in the first place. The answer is, a thought — “I want a drink” — enters our head. That thought is often referred to as an urge or a craving — and many believe that it’s the very root of addiction.
What do cravings feel like? It depends on the person, but when it comes to substance use, cravings are desires for something we wish we didn’t want (now that’s mind-bending, isn’t it?). By eliminating the craving, which is the result of brain chemistry conditioned by habitual alcohol use, we eliminate the “need” we feel to have that drink.
It’s important to understand that cravings are not “true” desires, and that as far as habits are concerned, “wanting” isn’t the same as “liking.” Dopamine makes us feel like we want things we don’t necessarily enjoy — that’s why we can feel the compulsion to keep drinking in spite of the fact that alcohol isn’t providing authentic enjoyment. At a certain point, if we’ve become dependent, even the illusion of pleasure disappears, while the craving only seems to grow stronger.
Medications that target cravings, in turn, help us interrupt the vicious cycle from the get-go. The result? We don’t have to pour that drink, taste it, and find it unsatisfying. We don’t have to safeguard ourselves from having it by taking medications that could send us to the emergency room if we mix them with booze. In fact, alcohol might not even cross our mind at all!
For those who are committed to being booze-free, Campral has been a popular option. One important caveat: it works over time and is meant for those who’ve left alcohol behind and are trying to stay away from it for good.
Pros:
Cons:
Topiramate, in turn, targets cravings by decreasing the dopamine release associated with alcohol use. The result? Just like the first category of drugs, Topamax makes booze lose its appeal. However, because the effect is indirect (we’re talking about the reward system as opposed to opioid receptors), it affects our desire for alcohol and — like Campral — lives in the realm of cravings.
Pros:
Cons:
Gabapentin is beneficial for managing withdrawal symptoms and reducing alcohol cravings. Developed as an antiseizure medication, it helps stabilize the brain’s electrical activity and has been shown to be effective in treating alcohol dependence.
Pros:
Cons:
Now that we’re familiar with the meds out there that can help us stop drinking or reduce our cravings, what do we do with this information? Here are some questions to consider as you decide if any one of these treatments might be the right course for you.
First and foremost, the answer depends on your goals. Those who want to quit completely and are committed to staying booze-free will have different needs from those who simply want alcohol to be less prominent in their lives.
And remember what we said about decision fatigue? Science says we make about 35,000 decisions a day. Needless to say, our brain gets tired from the constant back-and-forth.
When we throw medications for AUD into the mix, the number of daily decisions is a factor to keep in mind. Remember, we’re talking about the decision to take the medication as well as the decision whether or not to drink.
Finally, overall health is also an important factor. All medications have side effects, and those that help with AUD recovery are no exception. Plus, some of us may have additional needs that we’re trying to address with medications.
Finally, it’s important to keep in mind that if it turns out medication isn’t the right route for you, there are plenty of ways to stop drinking without it! For a deep dive, check out “How Easy Is It To Quit Drinking in 2024?” For now, here are some tips to start with:
And remember, no matter which approach you choose, it’s essential to have a support system behind you. If you’re looking for a community of like-minded people who’ve been where you are and are now thriving, the Reframe forum is a great place to start!
