Daily Research

Intermittent Movement for Brain Health

by Reframe Research Team • 5 min read
Intermittent movement, or breaking up long periods of sitting with short bursts of activity, has been shown to improve brain health by boosting blood flow, enhancing mood, and supporting cognitive function. Regular movement breaks reduce the risk of cognitive decline, improve mental clarity, and offer a natural way to manage stress, which can help reduce alcohol cravings. By incorporating small, consistent movements into your day, such as stretching or walking, you can counteract the negative effects of prolonged sitting and support both physical and mental well-being.

Many of us spend hours each day sitting, especially if we work at a desk or struggle with low energy. However, sitting for more than six hours a day has been linked to brain shrinkage in key areas related to memory and learning. This alarming discovery has sparked increased interest in intermittent movement — a practice that involves breaking up long periods of sitting with short bursts of activity.

In recent years, intermittent movement has been shown to improve brain function, enhance mood, and reduce the risks of prolonged sedentary behavior. Let’s take a closer look at how these quick movement breaks can make a remarkable difference in your physical and mental well-being as you continue to steer away from alcohol and adopt healthier habits.

Intermittent Movement and Health

Research is revealing just how damaging prolonged sitting can be for brain function — and how short, regular movement breaks can counteract these effects. Movement increases circulation and sends more oxygen and nutrients to the brain.[1] Studies have also shown that short bursts of physical activity can trigger the release of endorphins, improving mood and reducing stress levels.

But what about intermittent movement in particular? As two recent studies have shown, movement breaks during prolonged periods of sitting have a profound impact on the brain, particularly when it comes to creating new connections and letting go of old patterns — effects that make it easier to leave alcohol behind and adopt healthier habits.

Moving Into New Patterns: Intermittent Movement and Neuroplasticity

A 2020 Experimental Brain Research study linked intermittent movement to neuroplasticity — the brain’s ability to reorganize itself and make new connections.[2] This research team wanted to understand how different ways of breaking up three hours of prolonged sitting (or not breaking it up at all) would affect the brain’s ability to strengthen connections between nerve cells, a process known as neuroplasticity. Simply put, neuroplasticity is the brain’s way of “rewiring” itself in response to what we do.

They focused on the brain called the motor cortex, which controls movement. Increased communication between the motor cortex and the muscles — a concept known as corticospinal excitability — serves as a clear sign that the brain is primed for learning and adaptation. 

The participants were 16 middle-aged office workers who were not very active. Each person tried three different “sitting” scenarios in a random order, with each scenario lasting three hours:

  • SIT: Three hours of continuous sitting (with only a brief social pause every 30 minutes).
  • FPA: Three hours of sitting but every 30 minutes they did 3 minutes of light exercises, such as squats, calf raises, and knee lifts.
  • EXE: Two-and-a-half hours of sitting, followed by 25 minutes of moderate-intensity cycling.

Before and after each scenario, the researchers used special non-invasive brain stimulation (called TMS, or transcranial magnetic stimulation) to measure how well the motor cortex could activate the thumb muscle, and how easily certain “brakes” in the brain (known as short-interval intracortical inhibition) were turned on or off. They also delivered a “training-like” stimulation to the nerve and brain called paired associative stimulation to see how each scenario might help or hinder the brain’s plasticity. Here’s what they found:

  • After the SIT (no movement breaks) or the EXE (25 minutes of cycling at the end), the brain’s response in the motor cortex didn’t show a strong boost in plasticity.
  • In the FPA scenario, however, there was a clear rise in brain plasticity: the tiny bursts of movement seemed to help the motor cortex rewire more effectively after the stimulation.

The results are promising — especially for anyone who isn’t a fan of long workout sessions. As it turns out, short, frequent activity breaks appeared to do more for the brain’s plasticity than a single moderate workout at the end of the sitting period. The researchers suspect this might be because small bursts of exercise could increase attention or improve blood sugar control in a way that primes the brain for change — though they don’t know for sure yet. In any case, quick activity breaks act as a “reset button” for the brain and body and help the brain stay more flexible and responsive.

Intermittent movement breaks improve brain health by enhancing blood flow, boosting mood, and supporting mental clarity, offering an effective way to counter the negative effects of prolonged sitting.

Break Out of Boredom: How Movement Sparks Learning

A 2022 study in the International Journal of Environmental Research and Public Health put the link between movement and neuroplasticity to the test in a more intense environment geared toward learning — the college classroom.[3] The researchers set out to explore the effects of breaking up prolonged periods of sitting with movement. The short answer? Yes, classroom movement breaks and physically active learning lowers fatigue and sharpens focus rather than distracting students from the material.

The researchers collected results from 14 different studies covering nearly 6000 university students from around the world. Some studies introduced short bursts of exercise in the classroom, while others set up special standing desks or stationary bikes so students could learn while staying active. As it turned out, both approaches were a hit in the classroom and led to some tangible benefits.

  • Less fatigue, increased alertness. Many students said they felt less tired or sleepy after they began moving around in class. Several studies found improvements in focus, concentration, and overall feeling of wellbeing when students broke up their sitting time.
  • No harm to academic performance. In studies that measured grades or test scores, results showed no negative effects of introducing activity breaks. In fact, some students felt more energized and better able to pay attention—though the studies didn’t show a big boost in their actual grades, either.

All in all, the takeaway is clear: short, simple movement breaks can reap real benefits — even if it’s just getting up to do a few stretches or light exercises.

Adding Intermittent Movement to Your Day

Incorporating intermittent movement is simple and doesn’t require a complete overhaul of your routine. Here’s how to get started:

1. Set a Movement Timer

Set a reminder to get up and move every 30-60 minutes. When it chimes, stand up and do one to three minutes of gentle movement, such as shoulder rolls, a quick hallway walk, or a set of jumping jacks. The goal is to break up extended periods of sitting with small, consistent bursts of activity. Schedule these breaks into your calendar so they’re as non-negotiable as a meeting or class.

2. Take Micro-Movement Breaks

The 2022 review showed that even short classroom movement breaks — in some cases, just two to five minutes — decreased fatigue and improved focus. The key is to be consistent and make movement into a habit. Here are some tips:

  • Keep movements super simple: stand up, shake out your arms, roll your neck, or march in place.
  • If you’re at a desk, do chair stretches or ankle rotations — small but effective.
  • Aim for a micro-break every time you notice your energy lagging or your mind wandering.

3. Integrate Movement Into Daily Tasks

Both studies suggest that weaving movement into your normal routine (instead of adding a separate “exercise block”) can make it easier to stick to. This approach helped people stay active without feeling like they were sacrificing precious time. Here’s how you can find incorporate movement into your day:

  • Walk or stand when you can. Take phone calls on your feet or pace around the room.
  • Take the scenic route. Park farther away or walk to deliver a message instead of emailing.
  • Sneak in mini-routines. Try wall push-ups while waiting for the coffee to brew or calf raises when brushing your teeth.

4. Use Movement for Focus

Research shows that short active breaks increase attention and reduce fatigue — all beneficial for cognitive performance, whether you’re learning new material, tackling challenging tasks at work, or trying to shift to healthier habits around alcohol.

  • When mental fog sets in, step away from your workspace for a quick stroll or 2–3 minutes of light movement (e.g., jumping jacks, pacing, or simple yoga stretches).
  • Experiment with self-check timers: every 45–60 minutes, ask yourself, “Am I still focused?” If not, move for a couple of minutes.
  • For longer classes or meetings, propose a group stretch break — it’s often welcomed, and the science backs it up.

Summing Up

Intermittent movement is a powerful, science-backed strategy to improve brain health and break the harmful patterns of a sedentary lifestyle. Just a few minutes of activity throughout the day can boost your brain’s long-term health and resilience.

However, intermittent movement is more than just a strategy for breaking up sitting time — it’s a commitment to healing your brain and body from the inside out. Each stretch, step, and movement break is a message to your brain: you’re ready to learn, ready to grow, and ready to let go of old patterns that no longer serve you.

As you continue this journey, remember that healing is a dynamic process — one that’s built on the small choices we make daily. So, take that first step, stretch out those muscles, and let intermittent movement guide you toward lasting change.

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[1] Basso, Julia C and Wendy A Suzuki. “The Effects of Acute Exercise on Mood, Cognition, Neurophysiology, and Neurochemical Pathways: A Review.” (2017) Brain Plast, 2(2). 

https://pmc.ncbi.nlm.nih.gov/articles/PMC5928534/

[2] ​​Exp Brain Res. 2020 Aug 28;238(11):2497–2506. doi: 10.1007/s00221-020-05866-z

The effect of breaking up prolonged sitting on paired associative stimulation-induced plasticity

E Bojsen-Møller 1,✉, M M Ekblom 1,2, O Tarassova 1, D W Dunstan 3,4, O Ekblom

https://pmc.ncbi.nlm.nih.gov/articles/PMC7541377/

[3] Lynch, Julia, Gráinne O’Donoghue, and Casey L Peiris. “Classroom Movement Breaks and Physically Active Learning Are Feasible, Reduce Sedentary Behaviour and Fatigue, and May Increase Focus in University Students: A Systematic Review and Meta-Analysis.” (2022) Int J Environ Res Public Health, 19(13). https://pmc.ncbi.nlm.nih.gov/articles/PMC9265656/

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