Daily Research

Brain Health Series: Fish Oil

by Reframe Research Team • 3 min read
Rich in omega-3 fatty acids such as EPA and DHA, fish oil plays a crucial role in supporting brain health, reducing inflammation, and regulating mood. These healthy fats have been linked to a decrease in alcohol cravings, as they help stabilize brain chemistry and counteract withdrawal symptoms. Additionally, omega-3s aid in repairing brain cells damaged by alcohol and lowering inflammation throughout the body, supporting cognitive function and overall well-being.

Centuries ago, the practice of consuming fish oil gained traction in fishing communities in northern Europe, where fishermen would sip cod liver oil to fend off the harsh winter ailments. Today, science backs this age-old remedy as the key to brain health and mood regulation. 

Derived from the tissues of fatty fish like salmon, mackerel, and sardines, fish oil contains omega-3 fatty acids — crucial elements that the body cannot produce independently. These substances — EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) in particular — are essential for maintaining brain health. These molecules play a crucial role in brain function by reducing inflammation and supporting mood stability. Recent studies show they also play an important role in keeping alcohol cravings at bay. Let’s explore how fish oil can support your efforts as you shift to healthier habits.

Fish Oil Curbs Alcohol Cravings

A 2020 study in Current Neuropharmacology suggests that omega-3 fatty acids may directly impact alcohol cravings.[1] Researchers tested its effects on animals that were exposed to alcohol and began to seek it out as part of the experiment. The results showed that omega-3 supplements made all the difference: consuming them led to a significant reduction in alcohol intake, likely due to omega-3’s ability to modulate brain chemistry associated with substance misuse. While human studies are ongoing, these early findings suggest that fish oil could help reduce the urge to drink by stabilizing brain function and reducing withdrawal symptoms.

Rich in omega-3s, salmon is a natural way to boost brain health, support mood, and fight inflammation.

Restoring Brain Health and Regulating Mood 

Omega-3 fatty acids (especially DHA) are also vital for maintaining the structure and function of brain cells. Research shows that consistent fish oil consumption helps restore cell membranes damaged by alcohol use, making our memory sharper, enhancing focus, and boosting cognitive agility. It also keeps the brain healthy into old age while helping stave off dementia by lowering other risk factors (such as diabetes and cardiovascular disease).[2] 

Research also suggests that fish oil can help alleviate symptoms of depression and anxiety by acting as a natural mood stabilizer through its influence on serotonin and dopamine release — two key neurotransmitters involved in feelings of happiness and reward.[3] Omega-3s have been shown to increase the availability of these “feel-good” chemicals, which is especially beneficial when transitioning away from alcohol, as they help alleviate anxiety, stress, and depression.

Ways To Incorporate Fish Oil Into Your Routine

If you’re looking to harness the benefits of fish oil for alcohol reduction, here are some practical tips for adding it to your routine:

  • Include fatty fish in your diet. Incorporating fatty fish like salmon, mackerel, and sardines into your meals is another excellent way to boost your omega-3 intake. Aim for at least two servings of fatty fish per week for optimal brain and body support.
  • Pair fish oil with other healthy fats. To maximize the absorption of omega-3s, take fish oil supplements with a meal that contains healthy fats, such as avocados, nuts, or olive oil. This will enhance the bioavailability of the omega-3s and increase their effectiveness in reducing inflammation and supporting brain health.
  • Consider fish oil supplements. For those who don’t consume enough fatty fish, fish oil supplements are a convenient option. Be sure to choose a high-quality supplement that provides at least 1000 mg of combined EPA and DHA per serving. Consistency is key, so aim to take it daily to experience the full benefits.
Omega-3s in fish oil nourish the brain and boost well-being by regulating key neurotransmitters such as dopamine and serotonin.

A Note of Caution

Fish oil is safe for most of us, but always check with your doctor first, especially if you have underlying conditions or are taking medications. Fish oil shouldn't be mixed with blood-thinning medications like warfarin or aspirin, blood pressure medications such as beta-blockers, or diabetes medications like insulin, as it may enhance their effects and increase the risk of side effects.

Likewise, if you’re taking fish oil in supplement form, steer clear of other blood-thinning supplements like ginkgo biloba, garlic, or vitamin E, as it may increase the risk of excessive bleeding or bruising. It can also interact with blood pressure-lowering supplements, such as hawthorn or magnesium, and cause blood pressure to drop too low, leading to dizziness or lightheadedness. 

Summing Up

Fish oil, with its rich content of omega-3 fatty acids, offers a range of benefits that support brain health, mood stability, and inflammation reduction — all of which can be valuable assets in your journey to reduce alcohol consumption. By improving brain function, stabilizing mood, reducing cravings, and protecting the liver, fish oil provides a scientifically backed way to enhance your overall wellness as you work toward drinking less.

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[1] Galduróz, José Carlos F. OMEGA-3 Interventions in Alcohol Dependence and Related Outcomes: A Systematic Review and Propositions. (2020) Curr Neuropharmacol 18(5). https://pmc.ncbi.nlm.nih.gov/articles/PMC7457439/

[2] Cole, Greg M, Qiu-Lan Ma, and Sally A Frautschy. Omega-3 fatty acids and dementia. (2009) Prostaglandins Leukot Essent Fatty Acids 81(0):213–221. https://pmc.ncbi.nlm.nih.gov/articles/PMC4019002/#:~:text=DHA%20is%20broadly,and%20cardiovascular%20disease.

[3] Wani, Ab Latif , Sajad Ahmad Bhat, and Anjum Ara. Omega-3 fatty acids and the treatment of depression: a review of scientific evidence. (2015) Integr Med Res, 4(3). https://pmc.ncbi.nlm.nih.gov/articles/PMC5481805/#:~:text=There%20are%20number%20of%20studies%20which%20shows%20that%20omega%2D3%20fatty%20acids%20are%20proving%20to%20be%20very%20effective%20against%20the%20treatment%20of%20major%20depression%20disorder%20and%20other%20psychiatric%20disorders.

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