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Latest Articles
2024-05-07 9:00
Alcohol and Medications
Can You Drink Alcohol While Taking Keppra?
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Keppra is an anti-epileptic medication used to treat seizures in people with epilepsy. Check out our latest blog for more information about Keppra’s interactions with alcohol.

16 min read

Ready To Give Your Brain Some Love? Quit or Cut Back on Alcohol With Reframe!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today! 

Read Full Article  →

Having a seizure can be an unpleasant experience, especially for those with epilepsy. Keppra (known by the generic name levetiracetam) is commonly prescribed to treat seizures in epilepsy patients. But what about mixing Keppra and alcohol? How does Keppra affect us, and can we drink alcohol while taking it? Let’s learn more about levetiracetam and alcohol, and what happens if we mix the two.

Keppra may be prescribed to control various types of seizures, but it is not a cure for epilepsy. Therefore, most patients who are prescribed Keppra need to be on it for a long time and require a doctor’s supervision when they stop taking it.

What Is Keppra and How Does it Work?

A woman holding pills and a glass of wine

Keppra is part of a class of medications known as “anticonvulsants,” that are used to treat seizures in people with epilepsy. The exact dosage depends on the patient but is typically taken daily. The amount of time someone stays on Keppra also varies depending on the patient, but some take it for up to five years. If you stop taking it, it must be done slowly and under the guidance of a doctor.

There are few Keppra uses beyond treating epilepsy, but it is sometimes used to treat seizures during alcohol withdrawal.

But what causes a seizure? Seizures are caused by too much “excitatory” activity in the brain. Anticonvulsant drugs, in general, alter electrical activity in the brain’s neurons and increase GABA, which calms this excitatory activity. Keppra works by decreasing the excess excitation in the brain and increasing inhibition. 

Side Effects of Keppra

The side effects of Keppra vary depending on the type of seizure being treated, but they can all be pretty worrisome:

  • Aggression
  • Anxiety
  • Personality changes and mood swings
  • Drowsiness
  • Delusions
  • Uncontrolled anger (known as “Keppra rage”)
  • Feeling disconnected from reality
  • Depression and suicidal thoughts

If you are experiencing thoughts of suicide, please seek medical attention. In the United States, you can reach your local crisis hotline by dialing 988. Click here for a list of mental crisis phone numbers by country

Is There an Interaction Between Keppra and Alcohol?

So, we know what Keppra is and what it does, but what does the Keppra alcohol interaction do to us? Well, not only does it affect our brain, but it affects other parts of our body as well. Let’s examine each of these in more detail.

Effects on Our Brain

Remember those nasty side effects of Keppra we talked about earlier? Well, bringing alcohol into the mix can exacerbate them. Since alcohol affects the brain, it can interfere with the work that Keppra is trying to do to treat the brain. The combination can cause a range of reactions from increased drowsiness to extreme sedation to mood swings to depression to suicidal thoughts.

The use of alcohol on its own can induce a seizure in some people with epilepsy. Combine that with making Keppra less effective, and you have a recipe for trouble.

The bottom line is that it’s best to avoid alcohol while taking Keppra, and definitely not to have more than 14 units of alcohol per week if you do plan to drink.

Even if we’re not taking Keppra, alcohol is bad news for those of us with epilepsy. Consuming more than two drinks per day puts epileptics at risk for seizures, so it’s best to avoid it if you have epilepsy. Alcohol is actually one of the most common triggers for epileptic seizures.

While most alcohol-related seizures occur as a result of withdrawal, heavy alcohol use can increase the risk of developing seizures in people who don’t have epilepsy. One study shows that a person’s seizure threshold — meaning how likely the brain is to have a seizure — increases after heavy alcohol use (particularly three drinks or more per day).

Effects on the Central Nervous System

Both alcohol and Keppra depress the central nervous system (CNS), slowing down the body’s functions. When we combine multiple substances that depress the central nervous system, we set ourselves up for a major imbalance of chemicals in the brain that can lead to severe sedation and even a coma. Not only that, combining alcohol and Keppra can heighten each other’s side effects of dizziness or fatigue, both of which are symptoms of CNS depression. 

Effects on Our Liver

We know alcohol damages the liver, but what about Keppra? As it turns out, Keppra has been linked to liver damage in some rare cases. While the research on this is minimal, it’s not worth the risk of further damaging the liver by adding alcohol to the mix.

Effects on Our Kidneys

Alcohol damages the kidneys by disrupting the hormones that regulate kidney function. Keppra is mainly processed and eliminated by the kidneys, so any damage to the kidneys from alcohol means that the kidneys can’t eliminate as much Keppra from the body. This means our dosage of Keppra needs to be reduced, which gives us less protection against seizures.

Effects on Our Mood

We’ve talked about the side effects of Keppra and how mood swings and depression are among those. But did you know that alcohol also has a negative effect on our mood? While that first sip may make us feel relaxed and ready to socialize, alcohol can conjure up a whole lot of negative emotions. Once the alcohol has left our body, we experience a sudden decrease in GABA, the calming inhibitory neurotransmitter, which leads to feelings of restlessness, anxiety, and irritability (For more information, check out our blog “Why Does Alcohol Make Me Moody the Next Day?”). If we combine these negative effects of alcohol with the side effects of Keppra, we have a much higher risk of severe mood swings and suicidal thoughts.

How Long After Stopping Keppra Can I Drink Alcohol?

Say we’re ready to get off Keppra and have been slowly doing so under the supervision of our doctor, now what? How long do we need to wait if we plan to consume alcohol? It can take up to 44 hours for Keppra to be completely out of our system after the last dose, so it’s best to wait at least that long before consuming any alcohol. But just because our seizures are under control doesn’t mean we’re in the clear. Keep in mind that consuming more than two drinks per day puts epileptics at risk for seizures, so it’s best for anyone who has epilepsy to avoid alcohol. And since there is limited research on Keppra, and the dosage varies so widely among patients, it’s best to talk to your doctor before consuming any alcohol.

Tips for Taking Keppra Safely — Without Alcohol

Tips To Stay Safe While Taking Keppra

Mixing alcohol with Keppra has some pretty nasty effects, but luckily there are plenty of things we can do to stay safe and prioritize our health. Keep these tips in mind:

  1. Know your triggers. Flashing lights aren’t the only thing to watch out for when avoiding seizures. Alcohol is a common trigger for epileptic seizures, and so is lack of sleep. And since alcohol contributes to a lack of sleep, this effect is compounded. Not only that, hormone changes and dehydration are also linked to epileptic seizures, which alcohol also contributes to.
  2. Stick to non-alcoholic beverages during treatment. Mocktails are a safe alternative to alcohol as long as they are truly alcohol-free. Keep in mind that non-alcoholic beer still contains trace amounts of alcohol and may still interact with certain medications, so be sure to talk to your healthcare provider if you plan to drink it while taking Keppra.
  3. Seek support. Support from loved ones or a community can help tremendously during any treatment. We can also talk to our loved ones about our condition so we won’t feel put on the spot during activities that involve drinking.
  4. Practice brain-healthy activities. Activities such as yoga and meditation as well as practicing mindfulness can calm the brain, so instead of turning to that evening glass of wine to calm down, we can calm both our body and our mind in a healthy way. Studies show that meditation and practicing mindfulness can work wonders for epilepsy patients, so it won’t hurt to add some yoga or meditation to your daily routine (For some ideas for mindful activities to try out, check out our blog “11 Mindfulness Exercises and Activities for Adults”).

All of these activities will lead you down the road to better health and safety while taking Keppra.

A Bit of Brainy Inspiration

Undergoing treatment for epilepsy can be a lot to think about, and since the brain is such a complex piece of equipment, there are still many mechanisms to its interactions that we don’t fully understand (ironic, isn’t it, since we use our brains to study other brains.) Keppra in particular is understudied, which is even more reason to leave the booze behind when taking it. And just remember that we’re not only doing our brains a favor by cutting out the booze, we’re opening up our lives to a whole world of happier, healthier habits.

Having a seizure can be an unpleasant experience, especially for those with epilepsy. Keppra (known by the generic name levetiracetam) is commonly prescribed to treat seizures in epilepsy patients. But what about mixing Keppra and alcohol? How does Keppra affect us, and can we drink alcohol while taking it? Let’s learn more about levetiracetam and alcohol, and what happens if we mix the two.

Keppra may be prescribed to control various types of seizures, but it is not a cure for epilepsy. Therefore, most patients who are prescribed Keppra need to be on it for a long time and require a doctor’s supervision when they stop taking it.

What Is Keppra and How Does it Work?

A woman holding pills and a glass of wine

Keppra is part of a class of medications known as “anticonvulsants,” that are used to treat seizures in people with epilepsy. The exact dosage depends on the patient but is typically taken daily. The amount of time someone stays on Keppra also varies depending on the patient, but some take it for up to five years. If you stop taking it, it must be done slowly and under the guidance of a doctor.

There are few Keppra uses beyond treating epilepsy, but it is sometimes used to treat seizures during alcohol withdrawal.

But what causes a seizure? Seizures are caused by too much “excitatory” activity in the brain. Anticonvulsant drugs, in general, alter electrical activity in the brain’s neurons and increase GABA, which calms this excitatory activity. Keppra works by decreasing the excess excitation in the brain and increasing inhibition. 

Side Effects of Keppra

The side effects of Keppra vary depending on the type of seizure being treated, but they can all be pretty worrisome:

  • Aggression
  • Anxiety
  • Personality changes and mood swings
  • Drowsiness
  • Delusions
  • Uncontrolled anger (known as “Keppra rage”)
  • Feeling disconnected from reality
  • Depression and suicidal thoughts

If you are experiencing thoughts of suicide, please seek medical attention. In the United States, you can reach your local crisis hotline by dialing 988. Click here for a list of mental crisis phone numbers by country

Is There an Interaction Between Keppra and Alcohol?

So, we know what Keppra is and what it does, but what does the Keppra alcohol interaction do to us? Well, not only does it affect our brain, but it affects other parts of our body as well. Let’s examine each of these in more detail.

Effects on Our Brain

Remember those nasty side effects of Keppra we talked about earlier? Well, bringing alcohol into the mix can exacerbate them. Since alcohol affects the brain, it can interfere with the work that Keppra is trying to do to treat the brain. The combination can cause a range of reactions from increased drowsiness to extreme sedation to mood swings to depression to suicidal thoughts.

The use of alcohol on its own can induce a seizure in some people with epilepsy. Combine that with making Keppra less effective, and you have a recipe for trouble.

The bottom line is that it’s best to avoid alcohol while taking Keppra, and definitely not to have more than 14 units of alcohol per week if you do plan to drink.

Even if we’re not taking Keppra, alcohol is bad news for those of us with epilepsy. Consuming more than two drinks per day puts epileptics at risk for seizures, so it’s best to avoid it if you have epilepsy. Alcohol is actually one of the most common triggers for epileptic seizures.

While most alcohol-related seizures occur as a result of withdrawal, heavy alcohol use can increase the risk of developing seizures in people who don’t have epilepsy. One study shows that a person’s seizure threshold — meaning how likely the brain is to have a seizure — increases after heavy alcohol use (particularly three drinks or more per day).

Effects on the Central Nervous System

Both alcohol and Keppra depress the central nervous system (CNS), slowing down the body’s functions. When we combine multiple substances that depress the central nervous system, we set ourselves up for a major imbalance of chemicals in the brain that can lead to severe sedation and even a coma. Not only that, combining alcohol and Keppra can heighten each other’s side effects of dizziness or fatigue, both of which are symptoms of CNS depression. 

Effects on Our Liver

We know alcohol damages the liver, but what about Keppra? As it turns out, Keppra has been linked to liver damage in some rare cases. While the research on this is minimal, it’s not worth the risk of further damaging the liver by adding alcohol to the mix.

Effects on Our Kidneys

Alcohol damages the kidneys by disrupting the hormones that regulate kidney function. Keppra is mainly processed and eliminated by the kidneys, so any damage to the kidneys from alcohol means that the kidneys can’t eliminate as much Keppra from the body. This means our dosage of Keppra needs to be reduced, which gives us less protection against seizures.

Effects on Our Mood

We’ve talked about the side effects of Keppra and how mood swings and depression are among those. But did you know that alcohol also has a negative effect on our mood? While that first sip may make us feel relaxed and ready to socialize, alcohol can conjure up a whole lot of negative emotions. Once the alcohol has left our body, we experience a sudden decrease in GABA, the calming inhibitory neurotransmitter, which leads to feelings of restlessness, anxiety, and irritability (For more information, check out our blog “Why Does Alcohol Make Me Moody the Next Day?”). If we combine these negative effects of alcohol with the side effects of Keppra, we have a much higher risk of severe mood swings and suicidal thoughts.

How Long After Stopping Keppra Can I Drink Alcohol?

Say we’re ready to get off Keppra and have been slowly doing so under the supervision of our doctor, now what? How long do we need to wait if we plan to consume alcohol? It can take up to 44 hours for Keppra to be completely out of our system after the last dose, so it’s best to wait at least that long before consuming any alcohol. But just because our seizures are under control doesn’t mean we’re in the clear. Keep in mind that consuming more than two drinks per day puts epileptics at risk for seizures, so it’s best for anyone who has epilepsy to avoid alcohol. And since there is limited research on Keppra, and the dosage varies so widely among patients, it’s best to talk to your doctor before consuming any alcohol.

Tips for Taking Keppra Safely — Without Alcohol

Tips To Stay Safe While Taking Keppra

Mixing alcohol with Keppra has some pretty nasty effects, but luckily there are plenty of things we can do to stay safe and prioritize our health. Keep these tips in mind:

  1. Know your triggers. Flashing lights aren’t the only thing to watch out for when avoiding seizures. Alcohol is a common trigger for epileptic seizures, and so is lack of sleep. And since alcohol contributes to a lack of sleep, this effect is compounded. Not only that, hormone changes and dehydration are also linked to epileptic seizures, which alcohol also contributes to.
  2. Stick to non-alcoholic beverages during treatment. Mocktails are a safe alternative to alcohol as long as they are truly alcohol-free. Keep in mind that non-alcoholic beer still contains trace amounts of alcohol and may still interact with certain medications, so be sure to talk to your healthcare provider if you plan to drink it while taking Keppra.
  3. Seek support. Support from loved ones or a community can help tremendously during any treatment. We can also talk to our loved ones about our condition so we won’t feel put on the spot during activities that involve drinking.
  4. Practice brain-healthy activities. Activities such as yoga and meditation as well as practicing mindfulness can calm the brain, so instead of turning to that evening glass of wine to calm down, we can calm both our body and our mind in a healthy way. Studies show that meditation and practicing mindfulness can work wonders for epilepsy patients, so it won’t hurt to add some yoga or meditation to your daily routine (For some ideas for mindful activities to try out, check out our blog “11 Mindfulness Exercises and Activities for Adults”).

All of these activities will lead you down the road to better health and safety while taking Keppra.

A Bit of Brainy Inspiration

Undergoing treatment for epilepsy can be a lot to think about, and since the brain is such a complex piece of equipment, there are still many mechanisms to its interactions that we don’t fully understand (ironic, isn’t it, since we use our brains to study other brains.) Keppra in particular is understudied, which is even more reason to leave the booze behind when taking it. And just remember that we’re not only doing our brains a favor by cutting out the booze, we’re opening up our lives to a whole world of happier, healthier habits.

Alcohol and Medications
2024-05-06 9:00
Alcohol and Medications
Beta-Blockers and Alcohol: Interactions and Risks
This is some text inside of a div block.

Alcohol + Beta-blockers = a risky pair ⚠️ Mixing these can mess with your heart rate and blood pressure, leading to serious health risks. Learn more on today’s blog.

13 min read

On Beta-Blockers? Cutback or Quit Alcohol With Reframe!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today! 

Read Full Article  →

Picture this: you're enjoying a night out with friends, ready to unwind and let loose, but suddenly you remember you just started a new medication this week — propranolol. Is it still safe to throw back a few drinks?

In this post, you will learn how beta-blockers like propranolol work, how alcohol affects our cardiovascular health, how alcohol interacts with beta-blockers, and how to manage your relationship with alcohol while on beta-blockers. 

What Are Beta-Blockers?

a person pouring pills from a bottle into their other hand

Beta-blockers are a class of medication typically used to treat heart- and circulatory-related problems. However, because beta receptors are found in multiple locations throughout the body, beta-blockers can treat a wide range of problems: 

  • Heart arrhythmias
  • Chest pain (angina) 
  • Coronary artery disease
  • Heart attack or congestive heart failure
  • High blood pressure (hypertension)
  • Enlarged heart
  • Migraines
  • Glaucoma
  • Overactive thyroid (hyperthyroidism) 
  • Anxiety 

These are just some conditions that beta-blockers are used for. But how do beta-blockers work? 

How Do Beta-Blockers Work?

Beta-blockers work by blocking certain hormones from activating beta receptors, also called adrenergic receptors. There are three types of beta receptors: 

  • Beta-1 receptors. When activated, these receptors increase cardiac activity and activate the release of an enzyme found in our kidneys called renin. 
  • Beta-2 receptors. When activated, these relax our airways and lower blood pressure, but they may also cause muscle tremors.
  • Beta-3 receptors. When these are activated, they cause fat cells to break down, increase bladder capacity, and cause tremors. 

Since there are different beta receptors, beta-blockers often selectively target a specific type of beta receptor. Generally, beta-blockers fall into two categories based on whether they are cardioselective (beta-1 receptors) or not. Common cardioselective beta-blockers are atenolol, betaxolol, bisoprolol, esmolol, acebutolol, metoprolol, and nebivolol. Popular nonselective beta-blockers include propranolol, nadolol, pindolol, labetalol, trandate, penbutolol, or sotalol. 

Someone struggling with high blood pressure or anxiety, for example, might be prescribed propranolol, which blocks adrenaline (a stress hormone) from beta-1 receptors. The result is a decreased heart rate, making it easier for the heart to pump blood throughout your body.

While they are usually short-lived and mild, there are some side effects to be aware of: 

  • Feeling tired, dizzy, or lightheaded
  • Having cold fingers or toes 
  • Weight gain
  • Depression
  • Shortness of breath 
  • Difficulties sleeping or having nightmares

Not everyone will experience all the side effects associated with beta-blockers, but it’s good to be aware of them in case you do.

Alcohol’s Effects on the Heart

As we drink alcohol, it gets absorbed through the small intestines to the bloodstream. Once in our bloodstream, it has multiple effects on our cardiovascular system. Let’s take a look at how alcohol consumption affects our heart in the short and long term. 

In the short term, alcohol increases our heart rate and blood pressure and potentially leads to heart palpitations. Heart palpitations are a feeling of having a fast-beating, fluttering, or pounding heart that can feel worrisome, but they are harmless most of the time. After we are done drinking and the alcohol leaves our bloodstream, our blood pressure and heart rate go back to normal. 

When we drink heavily for a long time, we can damage our heart. Heavy drinking can result in tachycardia (when the heart beats too fast), high blood pressure, weakened heart muscles, irregular heartbeat, atrial fibrillation (the heart quivers instead of beats), or an enlarged heart. Many of these long-term effects on the heart can increase the chances of having a heart attack or stroke. Research shows us that heavy drinkers have more strokes and a greater chance of dying from strokes.

Side Effects of Mixing Alcohol and Beta-Blockers

Alcohol and Beta-Blockers

Interactions

Alcohol’s impact on beta-blockers ranges based on the type of beta-blocker. Alcohol and beta-blockers can be a dangerous mix. Alcohol may decrease the effectiveness of beta-blockers by changing how they are released into the body or the speed at which the body metabolizes them. Mixing metoprolol and alcohol, for example, can speed up the release of the drug into our body and decrease its effectiveness. On the other hand, mixing propranolol and alcohol or flecainide and alcohol might not reduce the effectiveness of the drugs but may enhance the effects of alcohol. 

Side Effects

In general, drinking while on beta-blockers can enhance the side effects associated with both alcohol and beta-blockers. Let’s review some side effects associated with drinking alcohol while on beta-blockers: 

  • Excessive sedation and dizziness. Alcohol use and beta-blockers can both cause dizziness and drowsiness. Combining the two can intensify the feelings and lead to more accidents and injuries. 
  • Hypotension. Hypotension is when our blood pressure gets below the normal level. When our blood pressure is too low, we don’t get enough blood to essential areas in our body such as the heart and brain. Beta-blockers and alcohol can lower blood pressure, so having them both can excessively lower our blood pressure and lead to fainting, dizziness, or shock. 
  • Tachycardia. Tachycardia is when our heart rate exceeds 100 beats per minute. Beta-blockers tend to slow our heart rate, and alcohol has the opposite effect. These conflicting actions can lead to tachycardia, irregular heartbeat, or heart palpitations. 
  • Worsened heart conditions. If we are on beta-blockers, we are likely prescribed them to manage issues of the heart. Alcohol consumption can make our heart conditions worse and interferes with the progress we made with the medication. 
  • Liver function. Alcohol is toxic to our liver and can cause long-term damage. Beta-blockers can also negatively impact our liver function, so mixing the two can compound the risks. 

If the associated risks haven’t deterred you, the question remains: can you drink on beta-blockers? While it is likely not life-threatening, most physicians won’t recommend it; however, it will largely depend on the type of beta-blocker in question. If we are using it for heart-related problems, alcohol probably isn’t safe. It’s always best to seek medical advice before we drink alcohol while on beta-blockers. 

Managing Our Relationship With Alcohol While on Beta-Blockers

Even if we know the associated risks, it may be hard to quit our current drinking habits. Let’s go through some tips on how we can have a healthy relationship with alcohol while we are on beta-blockers: 

  • Drink in moderation. Having one or two drinks while on beta-blockers is likely not life-threatening. However, make sure you consult with your prescribing physician before you drink any alcohol. 
  • Don’t skip your beta-blocker! You should never skip a dose of your beta-blocker to drink alcohol. Abruptly stopping beta-blockers can result in a thyroid storm, heart attack, anxiety, or hypertension. A thyroid storm can increase your heart rate, blood pressure, and body temperature to abnormally high levels and be life-threatening. 
  • Skip the alcohol. Instead of drinking alcohol, try alcohol-free alternatives such as mocktails or non-alcoholic beer
  • Plan ahead. If you are going to drink while on beta-blockers, make sure you prepare in advance. You can expect a stronger reaction to alcohol and may become extremely dizzy or drowsy. Make sure you have a trusted person to help you if you need it. 

Remember to consult your doctor before you drink alcohol while on beta-blockers.

The Bottom Line

Although not immediately life-threatening, it’s safest not to drink alcohol while taking beta-blockers. The mix of beta-blockers and alcohol can enhance the effects of alcohol and the side effects of the medication. Never skip a dose of your beta-blockers to drink alcohol, but drink in moderation if you want to drink while on beta-blockers.

Picture this: you're enjoying a night out with friends, ready to unwind and let loose, but suddenly you remember you just started a new medication this week — propranolol. Is it still safe to throw back a few drinks?

In this post, you will learn how beta-blockers like propranolol work, how alcohol affects our cardiovascular health, how alcohol interacts with beta-blockers, and how to manage your relationship with alcohol while on beta-blockers. 

What Are Beta-Blockers?

a person pouring pills from a bottle into their other hand

Beta-blockers are a class of medication typically used to treat heart- and circulatory-related problems. However, because beta receptors are found in multiple locations throughout the body, beta-blockers can treat a wide range of problems: 

  • Heart arrhythmias
  • Chest pain (angina) 
  • Coronary artery disease
  • Heart attack or congestive heart failure
  • High blood pressure (hypertension)
  • Enlarged heart
  • Migraines
  • Glaucoma
  • Overactive thyroid (hyperthyroidism) 
  • Anxiety 

These are just some conditions that beta-blockers are used for. But how do beta-blockers work? 

How Do Beta-Blockers Work?

Beta-blockers work by blocking certain hormones from activating beta receptors, also called adrenergic receptors. There are three types of beta receptors: 

  • Beta-1 receptors. When activated, these receptors increase cardiac activity and activate the release of an enzyme found in our kidneys called renin. 
  • Beta-2 receptors. When activated, these relax our airways and lower blood pressure, but they may also cause muscle tremors.
  • Beta-3 receptors. When these are activated, they cause fat cells to break down, increase bladder capacity, and cause tremors. 

Since there are different beta receptors, beta-blockers often selectively target a specific type of beta receptor. Generally, beta-blockers fall into two categories based on whether they are cardioselective (beta-1 receptors) or not. Common cardioselective beta-blockers are atenolol, betaxolol, bisoprolol, esmolol, acebutolol, metoprolol, and nebivolol. Popular nonselective beta-blockers include propranolol, nadolol, pindolol, labetalol, trandate, penbutolol, or sotalol. 

Someone struggling with high blood pressure or anxiety, for example, might be prescribed propranolol, which blocks adrenaline (a stress hormone) from beta-1 receptors. The result is a decreased heart rate, making it easier for the heart to pump blood throughout your body.

While they are usually short-lived and mild, there are some side effects to be aware of: 

  • Feeling tired, dizzy, or lightheaded
  • Having cold fingers or toes 
  • Weight gain
  • Depression
  • Shortness of breath 
  • Difficulties sleeping or having nightmares

Not everyone will experience all the side effects associated with beta-blockers, but it’s good to be aware of them in case you do.

Alcohol’s Effects on the Heart

As we drink alcohol, it gets absorbed through the small intestines to the bloodstream. Once in our bloodstream, it has multiple effects on our cardiovascular system. Let’s take a look at how alcohol consumption affects our heart in the short and long term. 

In the short term, alcohol increases our heart rate and blood pressure and potentially leads to heart palpitations. Heart palpitations are a feeling of having a fast-beating, fluttering, or pounding heart that can feel worrisome, but they are harmless most of the time. After we are done drinking and the alcohol leaves our bloodstream, our blood pressure and heart rate go back to normal. 

When we drink heavily for a long time, we can damage our heart. Heavy drinking can result in tachycardia (when the heart beats too fast), high blood pressure, weakened heart muscles, irregular heartbeat, atrial fibrillation (the heart quivers instead of beats), or an enlarged heart. Many of these long-term effects on the heart can increase the chances of having a heart attack or stroke. Research shows us that heavy drinkers have more strokes and a greater chance of dying from strokes.

Side Effects of Mixing Alcohol and Beta-Blockers

Alcohol and Beta-Blockers

Interactions

Alcohol’s impact on beta-blockers ranges based on the type of beta-blocker. Alcohol and beta-blockers can be a dangerous mix. Alcohol may decrease the effectiveness of beta-blockers by changing how they are released into the body or the speed at which the body metabolizes them. Mixing metoprolol and alcohol, for example, can speed up the release of the drug into our body and decrease its effectiveness. On the other hand, mixing propranolol and alcohol or flecainide and alcohol might not reduce the effectiveness of the drugs but may enhance the effects of alcohol. 

Side Effects

In general, drinking while on beta-blockers can enhance the side effects associated with both alcohol and beta-blockers. Let’s review some side effects associated with drinking alcohol while on beta-blockers: 

  • Excessive sedation and dizziness. Alcohol use and beta-blockers can both cause dizziness and drowsiness. Combining the two can intensify the feelings and lead to more accidents and injuries. 
  • Hypotension. Hypotension is when our blood pressure gets below the normal level. When our blood pressure is too low, we don’t get enough blood to essential areas in our body such as the heart and brain. Beta-blockers and alcohol can lower blood pressure, so having them both can excessively lower our blood pressure and lead to fainting, dizziness, or shock. 
  • Tachycardia. Tachycardia is when our heart rate exceeds 100 beats per minute. Beta-blockers tend to slow our heart rate, and alcohol has the opposite effect. These conflicting actions can lead to tachycardia, irregular heartbeat, or heart palpitations. 
  • Worsened heart conditions. If we are on beta-blockers, we are likely prescribed them to manage issues of the heart. Alcohol consumption can make our heart conditions worse and interferes with the progress we made with the medication. 
  • Liver function. Alcohol is toxic to our liver and can cause long-term damage. Beta-blockers can also negatively impact our liver function, so mixing the two can compound the risks. 

If the associated risks haven’t deterred you, the question remains: can you drink on beta-blockers? While it is likely not life-threatening, most physicians won’t recommend it; however, it will largely depend on the type of beta-blocker in question. If we are using it for heart-related problems, alcohol probably isn’t safe. It’s always best to seek medical advice before we drink alcohol while on beta-blockers. 

Managing Our Relationship With Alcohol While on Beta-Blockers

Even if we know the associated risks, it may be hard to quit our current drinking habits. Let’s go through some tips on how we can have a healthy relationship with alcohol while we are on beta-blockers: 

  • Drink in moderation. Having one or two drinks while on beta-blockers is likely not life-threatening. However, make sure you consult with your prescribing physician before you drink any alcohol. 
  • Don’t skip your beta-blocker! You should never skip a dose of your beta-blocker to drink alcohol. Abruptly stopping beta-blockers can result in a thyroid storm, heart attack, anxiety, or hypertension. A thyroid storm can increase your heart rate, blood pressure, and body temperature to abnormally high levels and be life-threatening. 
  • Skip the alcohol. Instead of drinking alcohol, try alcohol-free alternatives such as mocktails or non-alcoholic beer
  • Plan ahead. If you are going to drink while on beta-blockers, make sure you prepare in advance. You can expect a stronger reaction to alcohol and may become extremely dizzy or drowsy. Make sure you have a trusted person to help you if you need it. 

Remember to consult your doctor before you drink alcohol while on beta-blockers.

The Bottom Line

Although not immediately life-threatening, it’s safest not to drink alcohol while taking beta-blockers. The mix of beta-blockers and alcohol can enhance the effects of alcohol and the side effects of the medication. Never skip a dose of your beta-blockers to drink alcohol, but drink in moderation if you want to drink while on beta-blockers.

Alcohol and Medications
2024-04-27 9:00
Alcohol and Medications
Can You Drink on Metronidazole?
This is some text inside of a div block.

Taking metronidazole and wondering what happens if you mix it with alcohol? Our latest blog has the answers!

18 min read

Ready To Meet the Healthiest Version of Yourself? Try Reframe!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today! 

Read Full Article  →

It’s a common story: you go to a doctor, walk away with a prescription for your condition, then drive to your local pharmacy to pick it up. You’re excited, thinking how much better you’ll feel soon. You take it out of the crinkly paper bag, tear off what seems like an entire stack of papers with information in tiny print stapled onto it, and glance at it before tossing it into the recycling bin. Then something on the orange bottle catches your eye — that little wine glass with a line across it: “Don’t consume with alcohol!”

Yikes. It’s too late to get all those papers back to find out why, so you take your questions to Google: “Can you drink on metronidazole?” It’s probably not that bad, right? What’s all this about the disulfiram-like reaction between metronidazole and booze? Before you give yourself a panic attack searching for things like “Can metronidazole and alcohol kill you?” let’s get the facts straight. What exactly happens if you accidentally drink alcohol while taking metronidazole?

What Is Metronidazole?

A person's hand holding a glass of whiskey with ice cubes

According to the National Library of Medicine, metronidazole (better known by the brand name Flagyl) is one of the go-to drugs for the treatment of infections. It’s equipped to handle several conditions: 

  • Intestinal amebiases
  • Liver amebiasis
  • Bacterial septicemia
  • Bone and joint infections
  • Meningitis
  • Brain abscess
  • Endocarditis
  • Endometritis
  • Bacterial vaginosis
  • Intra-abdominal infections
  • Lower respiratory tract infections
  • Skin structure infections
  • Surgical prophylaxis colorectal surgeries

That’s quite a long job description! And there’s even more. Topical metronidazole can treat a few gnarly infections, such as rosacea and bacterial vaginosis. Plus, it has several off-label uses: 

  • Bite wound infections from animals
  • Infections from human bites (eek!)
  • Clostridioides (formerly Clostridium difficile)
  • Crohn’s disease
  • Postsurgical resection management
  • Giardiasis
  • Periodontitis
  • Tetanus

How Does Metronidazole Work?

Flagyl works by attacking bacterial DNA through a four-step process. Here’s the gist:

  1. Breaking the barrier and taking out the anaerobes. Metronidazole breaks through the cell barriers of anaerobic and aerobic bacteria but only kills the first type of pathogen.
  2. Upgrading equipment. With the anaerobes out of the way, it’s time to attack the second enemy! However, this requires different equipment. Metronidazole undergoes reductive activation by special proteins, which change its chemical structure to allow it to torpedo the aerobes.
  3. Storming the command center. The next step? Destroying the “enemy’s” DNA. Metronidazole interacts with the host cells’ DNA, resulting in breakage and “fatal destabilization.”
  4. Cleaning up the mess. Final step? Breaking down the toxic byproducts of the reaction.

While metronidazole is quickly absorbed, it might take a couple of days to start feeling better. However, once it gets going, the medication does a powerful job of clearing out the infection.

Can You Drink on Metronidazole?

In general, Flagyl doesn’t mix well with other substances, including alcohol. This isn’t all that surprising — for one thing, alcohol tends to intensify the side effects of many medications. In the case of metronidazole, there are quite a few:

  • Headaches. Many people on metronidazole experience headaches. Since alcohol is known for causing the notorious “cocktail headaches,” adding it to the mix isn’t doing us any favors.
  • Digestive disruption. Some have gastrointestinal effects, including loss of appetite, nausea and vomiting, diarrhea, heartburn, or cramping in the stomach area, and constipation while taking metronidazole. Alcohol can disrupt digestion, causing nausea, heartburn, and even leading to gastritis. Needless to say, this makes for a potentially stomach-turning combo!
  • Metallic taste. Metronidazole might also cause a metallic taste in our mouth — so whatever we’re drinking might not taste that great.

In addition to these common side effects, there are some potentially serious (but rare) side effects of metronidazole that don’t mix well with booze: 

  • Seizures. The potentially serious side effects of metronidazole include seizures. In large amounts, alcohol has been known to induce seizures as well (as does alcohol withdrawal), so combining the two could be even more dangerous. It’s important to stay vigilant and be aware of telltale symptoms such as unusual behaviors or sensations, uncontrollable movements, or, in severe cases, loss of consciousness.
  • Cancer risk. As the warning label on metronidazole says, it may also be carcinogenic based on animal studies. Given that alcohol is a known carcinogen as well, the combo isn’t great.
  • Possible brain damage. If used for a long time, metronidazole could be neurotoxic. Knowing what alcohol does to our brain, the mixture of the two could cause serious trouble.
Staying Safe When Drinking on Metronidazole

Metronidazole and Alcohol: What Else Is Behind the Warning?

If you’re taking disulfiram — a medication used to treat alcohol use disorder (AUD) — there’s yet another reason to pause and reconsider before taking metronidazole.

Disulfiram works by causing extremely unpleasant side effects, such as facial flushing, nausea, and cardiovascular abnormalities. The idea is that taking disulfiram will make drinking so unenjoyable we won’t want to do it anymore. (For more details, check out our blog “How Does Disulfiram Work?”)

What does any of this have to do with Flagyl? As it turns out, metronidazole has a negative, and potentially dangerous, interaction with both alcohol and disulfiram.

Let’s look at both effects in a bit more detail:

  1. Metronidazole is thought to induce a “disulfiram-like” reaction when mixed with alcohol. When we combine alcohol with metronidazole, we might experience nausea, vomiting, stomach cramps, headaches, and facial flushing. According to a recent study, it doesn’t make much to trigger the reaction!
  2. Metronidazole also doesn't mix well with disulfiram. Taking both medications puts us at risk of hallucinations and psychosis (definitely not what we want, especially when we’re already not feeling our best!).

Negative Interactions Between Metronidazole and Alcohol: Myth or Science?

Some scientists now think that the side effects of mixing metronidazole and alcohol are a myth. 

According to an Emergency Medical News article, doctors have been warning patients against mixing the two for years to avoid a “disulfiram-like reaction.” And yet, the author asks:
 

“If this interaction is so important, where were the cases? Millions of prescriptions for metronidazole are written each year. Despite clear warnings, it's inevitable that a significant number of patients would continue to consume alcohol with the drug. Yet I've never seen a patient come in with a disulfiram-like reaction from that combination. Is the metronidazole-ethanol drug interaction really a thing?”

The author goes on to explain how the accumulation of acetaldehyde is responsible for the disulfiram reaction and how the “original thinking” was that metronidazole also blocked its breakdown. However, as he points out, recent evidence shows that this might not be the case. When 18 patients who were on metronidazole were compared with a control group who had a similar blood alcohol concentration, none seemed to show any signs of a disulfiram-like reaction. 

Likewise, a study in WMJ set out to investigate whether or not there was any truth to the disulfiram-like reaction claims and found that the answer isn’t as clear as scientists once thought. Their findings suggest that there’s no increase in acetaldehyde when both substances are present in our system.

How Long After Taking Metronidazole Can I Drink Alcohol?

Still, disulfiram-like reaction or not, metronidazole does interact with alcohol in potentially problematic ways, so the recommended wait period is at least two weeks for disulfiram and three days for alcohol after taking it. 

What If I Already Had a Drink?

Some of us might be thinking, “Oh no! What if I already had a drink before that warning label on the medicine package caught my eye?”

First of all, don’t panic. This probably happens quite often, and usually leads to no harmful effects, according to the Emergency Medical News study. However, it’s good to keep in mind that this is just one study arguing against the negative effects, and even if the “metronidazole and alcohol myth” is responsible for the alcohol warning, there are still other reasons why Flagyl and alcohol are not a good mix.

So, can metronidazole and alcohol kill you? It almost certainly won’t, especially given the evidence that there might not be a disulfiram-like reaction at play after all. 

Still, it’s best to stay vigilant and avoid mixing metronidazole and alcohol. And if there’s any doubt in your mind at all that you’re having a dangerous reaction, please don’t hesitate to call your doctor immediately! There are many individual factors at play here, so erring on the side of safety is key.

Tips To Stay Safe

So, how can we stay safe while taking metronidazole as we’re trying to stay away from booze for the time being (or, perhaps, for even longer)? Here are a few ideas:

  1. Avoid the mix. Mixing alcohol and metronidazole is asking for trouble. Instead, focus on healing and nourishing your body with plenty of water and vitamin-rich foods. You’ll heal faster and your body will thank you!
  2. Follow your doctor’s advice. Always follow your physician’s advice about taking medications, and don’t hesitate to ask if you have questions. They’re there to help!
  3. Get support. If you’re having trouble staying booze-free, find like-minded people who will be happy to support you. They can be friends, family members, or others just like you who are already part of the Reframe community! Everyone’s alcohol journey is different, so whatever your goals are, you’re bound to find helpful advice and support.
  4. Get sober curious. Use this time as an opportunity to explore a sober-curious lifestyle. Approach it as an experiment — what if instead of having a glass of wine with dinner you had a fun mocktail instead? Who knows, you might find a new favorite! Plus, a hydrating, nutritious drink is bound to make you feel better as you heal.

Summing Up

In the end, as with any situation that compels us to set alcohol aside for a bit, it’s always best to see the situation as an opportunity. Perhaps it’s even a blessing in disguise! Who knows, by going booze-free for a few days or weeks, you might discover new activities you love or find that you enjoy waking up feeling refreshed. Maybe your skin looks better or maybe you’ve even dropped some weight. All in all, you might see that cutting back is something you want to continue in the long run to see what new benefits are waiting for you (and trust us, there are lots!). If so, Reframe is here to help you and cheer you on every step of the way.

It’s a common story: you go to a doctor, walk away with a prescription for your condition, then drive to your local pharmacy to pick it up. You’re excited, thinking how much better you’ll feel soon. You take it out of the crinkly paper bag, tear off what seems like an entire stack of papers with information in tiny print stapled onto it, and glance at it before tossing it into the recycling bin. Then something on the orange bottle catches your eye — that little wine glass with a line across it: “Don’t consume with alcohol!”

Yikes. It’s too late to get all those papers back to find out why, so you take your questions to Google: “Can you drink on metronidazole?” It’s probably not that bad, right? What’s all this about the disulfiram-like reaction between metronidazole and booze? Before you give yourself a panic attack searching for things like “Can metronidazole and alcohol kill you?” let’s get the facts straight. What exactly happens if you accidentally drink alcohol while taking metronidazole?

What Is Metronidazole?

A person's hand holding a glass of whiskey with ice cubes

According to the National Library of Medicine, metronidazole (better known by the brand name Flagyl) is one of the go-to drugs for the treatment of infections. It’s equipped to handle several conditions: 

  • Intestinal amebiases
  • Liver amebiasis
  • Bacterial septicemia
  • Bone and joint infections
  • Meningitis
  • Brain abscess
  • Endocarditis
  • Endometritis
  • Bacterial vaginosis
  • Intra-abdominal infections
  • Lower respiratory tract infections
  • Skin structure infections
  • Surgical prophylaxis colorectal surgeries

That’s quite a long job description! And there’s even more. Topical metronidazole can treat a few gnarly infections, such as rosacea and bacterial vaginosis. Plus, it has several off-label uses: 

  • Bite wound infections from animals
  • Infections from human bites (eek!)
  • Clostridioides (formerly Clostridium difficile)
  • Crohn’s disease
  • Postsurgical resection management
  • Giardiasis
  • Periodontitis
  • Tetanus

How Does Metronidazole Work?

Flagyl works by attacking bacterial DNA through a four-step process. Here’s the gist:

  1. Breaking the barrier and taking out the anaerobes. Metronidazole breaks through the cell barriers of anaerobic and aerobic bacteria but only kills the first type of pathogen.
  2. Upgrading equipment. With the anaerobes out of the way, it’s time to attack the second enemy! However, this requires different equipment. Metronidazole undergoes reductive activation by special proteins, which change its chemical structure to allow it to torpedo the aerobes.
  3. Storming the command center. The next step? Destroying the “enemy’s” DNA. Metronidazole interacts with the host cells’ DNA, resulting in breakage and “fatal destabilization.”
  4. Cleaning up the mess. Final step? Breaking down the toxic byproducts of the reaction.

While metronidazole is quickly absorbed, it might take a couple of days to start feeling better. However, once it gets going, the medication does a powerful job of clearing out the infection.

Can You Drink on Metronidazole?

In general, Flagyl doesn’t mix well with other substances, including alcohol. This isn’t all that surprising — for one thing, alcohol tends to intensify the side effects of many medications. In the case of metronidazole, there are quite a few:

  • Headaches. Many people on metronidazole experience headaches. Since alcohol is known for causing the notorious “cocktail headaches,” adding it to the mix isn’t doing us any favors.
  • Digestive disruption. Some have gastrointestinal effects, including loss of appetite, nausea and vomiting, diarrhea, heartburn, or cramping in the stomach area, and constipation while taking metronidazole. Alcohol can disrupt digestion, causing nausea, heartburn, and even leading to gastritis. Needless to say, this makes for a potentially stomach-turning combo!
  • Metallic taste. Metronidazole might also cause a metallic taste in our mouth — so whatever we’re drinking might not taste that great.

In addition to these common side effects, there are some potentially serious (but rare) side effects of metronidazole that don’t mix well with booze: 

  • Seizures. The potentially serious side effects of metronidazole include seizures. In large amounts, alcohol has been known to induce seizures as well (as does alcohol withdrawal), so combining the two could be even more dangerous. It’s important to stay vigilant and be aware of telltale symptoms such as unusual behaviors or sensations, uncontrollable movements, or, in severe cases, loss of consciousness.
  • Cancer risk. As the warning label on metronidazole says, it may also be carcinogenic based on animal studies. Given that alcohol is a known carcinogen as well, the combo isn’t great.
  • Possible brain damage. If used for a long time, metronidazole could be neurotoxic. Knowing what alcohol does to our brain, the mixture of the two could cause serious trouble.
Staying Safe When Drinking on Metronidazole

Metronidazole and Alcohol: What Else Is Behind the Warning?

If you’re taking disulfiram — a medication used to treat alcohol use disorder (AUD) — there’s yet another reason to pause and reconsider before taking metronidazole.

Disulfiram works by causing extremely unpleasant side effects, such as facial flushing, nausea, and cardiovascular abnormalities. The idea is that taking disulfiram will make drinking so unenjoyable we won’t want to do it anymore. (For more details, check out our blog “How Does Disulfiram Work?”)

What does any of this have to do with Flagyl? As it turns out, metronidazole has a negative, and potentially dangerous, interaction with both alcohol and disulfiram.

Let’s look at both effects in a bit more detail:

  1. Metronidazole is thought to induce a “disulfiram-like” reaction when mixed with alcohol. When we combine alcohol with metronidazole, we might experience nausea, vomiting, stomach cramps, headaches, and facial flushing. According to a recent study, it doesn’t make much to trigger the reaction!
  2. Metronidazole also doesn't mix well with disulfiram. Taking both medications puts us at risk of hallucinations and psychosis (definitely not what we want, especially when we’re already not feeling our best!).

Negative Interactions Between Metronidazole and Alcohol: Myth or Science?

Some scientists now think that the side effects of mixing metronidazole and alcohol are a myth. 

According to an Emergency Medical News article, doctors have been warning patients against mixing the two for years to avoid a “disulfiram-like reaction.” And yet, the author asks:
 

“If this interaction is so important, where were the cases? Millions of prescriptions for metronidazole are written each year. Despite clear warnings, it's inevitable that a significant number of patients would continue to consume alcohol with the drug. Yet I've never seen a patient come in with a disulfiram-like reaction from that combination. Is the metronidazole-ethanol drug interaction really a thing?”

The author goes on to explain how the accumulation of acetaldehyde is responsible for the disulfiram reaction and how the “original thinking” was that metronidazole also blocked its breakdown. However, as he points out, recent evidence shows that this might not be the case. When 18 patients who were on metronidazole were compared with a control group who had a similar blood alcohol concentration, none seemed to show any signs of a disulfiram-like reaction. 

Likewise, a study in WMJ set out to investigate whether or not there was any truth to the disulfiram-like reaction claims and found that the answer isn’t as clear as scientists once thought. Their findings suggest that there’s no increase in acetaldehyde when both substances are present in our system.

How Long After Taking Metronidazole Can I Drink Alcohol?

Still, disulfiram-like reaction or not, metronidazole does interact with alcohol in potentially problematic ways, so the recommended wait period is at least two weeks for disulfiram and three days for alcohol after taking it. 

What If I Already Had a Drink?

Some of us might be thinking, “Oh no! What if I already had a drink before that warning label on the medicine package caught my eye?”

First of all, don’t panic. This probably happens quite often, and usually leads to no harmful effects, according to the Emergency Medical News study. However, it’s good to keep in mind that this is just one study arguing against the negative effects, and even if the “metronidazole and alcohol myth” is responsible for the alcohol warning, there are still other reasons why Flagyl and alcohol are not a good mix.

So, can metronidazole and alcohol kill you? It almost certainly won’t, especially given the evidence that there might not be a disulfiram-like reaction at play after all. 

Still, it’s best to stay vigilant and avoid mixing metronidazole and alcohol. And if there’s any doubt in your mind at all that you’re having a dangerous reaction, please don’t hesitate to call your doctor immediately! There are many individual factors at play here, so erring on the side of safety is key.

Tips To Stay Safe

So, how can we stay safe while taking metronidazole as we’re trying to stay away from booze for the time being (or, perhaps, for even longer)? Here are a few ideas:

  1. Avoid the mix. Mixing alcohol and metronidazole is asking for trouble. Instead, focus on healing and nourishing your body with plenty of water and vitamin-rich foods. You’ll heal faster and your body will thank you!
  2. Follow your doctor’s advice. Always follow your physician’s advice about taking medications, and don’t hesitate to ask if you have questions. They’re there to help!
  3. Get support. If you’re having trouble staying booze-free, find like-minded people who will be happy to support you. They can be friends, family members, or others just like you who are already part of the Reframe community! Everyone’s alcohol journey is different, so whatever your goals are, you’re bound to find helpful advice and support.
  4. Get sober curious. Use this time as an opportunity to explore a sober-curious lifestyle. Approach it as an experiment — what if instead of having a glass of wine with dinner you had a fun mocktail instead? Who knows, you might find a new favorite! Plus, a hydrating, nutritious drink is bound to make you feel better as you heal.

Summing Up

In the end, as with any situation that compels us to set alcohol aside for a bit, it’s always best to see the situation as an opportunity. Perhaps it’s even a blessing in disguise! Who knows, by going booze-free for a few days or weeks, you might discover new activities you love or find that you enjoy waking up feeling refreshed. Maybe your skin looks better or maybe you’ve even dropped some weight. All in all, you might see that cutting back is something you want to continue in the long run to see what new benefits are waiting for you (and trust us, there are lots!). If so, Reframe is here to help you and cheer you on every step of the way.

Alcohol and Medications
2024-04-27 9:00
Alcohol and Medications
Can You Drink on Macrobid? What Are the Risks?
This is some text inside of a div block.

Macrobid and alcohol don't directly interact. However, mixing the two can still be risky. Check out our latest blog for info on why drinking on Macrobid is not recommended.

15 min read

Prioritize Your Health With Reframe!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today! 

Read Full Article  →

You’ve just been prescribed Macrobid, and you’re ready to finally kick this infection. Especially because tomorrow is your friend’s birthday party — and it’s going to be lit! You’re looking forward to having a few drinks, and you’ve already preordered your Uber for the drive home.

A quick glance at the leaflet from the pharmacy says you should be okay to drink on Macrobid, so you don’t need to worry — right?

Just because we can eat all the cookies in the cookie jar doesn’t mean it’s healthy to do so. Even though there aren’t any direct interactions between alcohol and Macrobid, there can be adverse effects to mixing the two. Let’s examine these effects further; well-informed decisions require well-formed knowledge!

What Is Macrobid?

woman holding a glass of alcohol and a pill

Macrobid (a.k.a., nitrofurantoin) is an antibiotic that is used to treat bacterial infections, most commonly urinary tract infections (UTIs). The antibiotic is different from other, more common antibiotics; it collects in the urine, making it a good choice for infections involving the lower urinary tract. It’s one of the most common prescriptions in the United States with roughly 4 million prescriptions per year. Macrobid only works against bacterial infections, not viral infections of the urinary tract (such as BK virus, adenovirus, or herpes simplex virus). 

The medication starts working within a couple of hours, and it is typically taken for 5-7 days. Several side effects are associated with Macrobid:

  • Nausea 
  • Headache
  • Dizziness
  • Joint or muscle pain
  • Swelling
  • Shortness of breath
  • General discomfort (malaise)

In very rare cases, Macrobid can cause damage to lungs, liver, and nerves. However, Macrobid is regarded as generally safe to use.

Are Macrobid and Nitrofurantoin the Same Thing?

Macrobid is the brand-name version of the generic drug nitrofurantoin. Brand-name Macrobid contains nitrofurantoin in both slow-release macrocrystal form and a quick-acting liquid monohydrate form. Together, this attacks an acute UTI from two angles. (Other nitrofurantoin formulations contain only macrocrystals and are usually used as a preventative to avoid UTIs.)

Our doctor will prescribe the appropriate form of nitrofurantoin to treat our specific circumstances. The most important thing is to take it as prescribed and read all directions and warning labels.

Systemic Effects of Macrobid and Alcohol

So, can you drink alcohol while taking nitrofurantoin? The answer is complicated. Although Macrobid and alcohol don't have any direct interactions, mixing them can interfere with the drug’s effectiveness, damage our liver, and slow down our recovery from infection.

  • Liver metabolization. Most drugs are metabolized by the liver — including Macrobid. Using both at the same time can stress out the liver and inhibit its ability to effectively eliminate the toxic byproducts of alcohol metabolism, possibly leaving us with a nasty hangover. Proper liver function is crucial in helping break down toxins at an appropriate rate to prevent them from causing negative effects on other organs and systems in our body.
  • Decreased immune function. Our immune system’s main role is to help fight infection and keep us healthy. When recovering from a UTI, a strong immune system is critical to eliminating the infection because the Macrobid is only a boost to our body’s natural bacteria-fighting power. Alcohol dampens the function of our immune system, taking away precious resources and prolonging recovery. 

  • Dehydration. Alcohol is a diuretic, meaning it makes us pee. Hydration is essential for treating a UTI because peeing regularly prevents further bacteria growth. While alcohol can cause us to urinate a lot in the short term, the result is that we’re left dehydrated and playing catchup to restore our fluid levels.
  • Medication adherence. Nitrofurantoin is prescribed for 5-7 days to ensure the infection is completely eliminated. Although symptoms may start to go away before then, the entire round of antibiotics is recommended for full effectiveness. Alcohol is correlated with decreased inhibitions and impacted judgment. Research has shown that drinking may influence a patient's adherence to taking daily medication, which may increase the risk of UTI recurrence. 

Despite no acute interactions, it’s clear that alcohol can still interfere with nitrofurantoin. While the above conditions can complicate UTI treatment, there are also some ways that .

Risks of Drinking Alcohol While On Macrobid

Risks of Drinking on Nitrofurantoin

To make more mindful decisions when drinking while on nitrofurantoin, it’s important to know what we may be getting into:

  • Increased side effects. UTIs are painful and unpleasant. Alcohol can further exacerbate symptoms, increase side effects from medication, and heighten the risk of experiencing hangover symptoms — compounding the uncomfortable experience. Choosing to drink while on nitrofurantoin is like holding up a big welcome sign to usher in unpleasant symptoms such as nausea, vomiting, headache, and stomach pain.
  • Decreased effectiveness. Alcohol’s impact on our immune system and hormones can affect our body’s ability to fight against infection — indirectly dampening the effectiveness of nitrofurantoin.
  • Risk of liver damage. Prolonged and excessive drinking is associated with liver damage and disease. When our liver is in overdrive trying to break down alcohol and other drugs in our system, it’s less efficient at eliminating toxic substances that cause damage to our cells and organs. While on nitrofurantoin, alcohol can create the perfect storm that may lead to liver damage or disease.

We may have missed the tiny print on the back of the bottle warning us of these potential risks. If we’ve already had a drink or two while taking nitrofurantoin, should we be concerned?

What To Do If You’ve Already Consumed Alcohol With Nitrofurantoin

First of all: don’t panic! You’re going to be okay; plus, high stress levels can negatively impact recovery and lead us to make rash decisions through black-and-white thinking

Avoid further drinking and make sure to continue taking the medication as directed. Immediate symptoms may not show up after drinking, and it shouldn’t cause any immediate risk to health. If symptoms do arise, keep track of them and reach out to a doctor.

How Long After Taking Nitrofurantoin Can You Drink Alcohol?

Drinking while on nitrofurantoin isn’t recommended, but what about after? Similar to drinking while on the medication, drinking after finishing treatment may not cause immediate risks or direct impacts. However, it’s recommended to wait at least 48 hours after finishing nitrofurantoin to resume drinking.

Even after finishing the round of antibiotics, there’s still the chance of a lingering infection. Take it easy on alcohol — or better yet, avoid it all together — for a week or two after finishing treatment. This allows the body a better chance to fight off any infection that could still be present. Drinking immediately after finishing treatment will not cause any significant dangers (beyond the regular dangers of alcohol), but making intentional choices sets us up for the most successful and safe recovery.

Approaching Safe Consumption of Nitrofurantoin and Alcohol 

If we choose to drink, mindful practices can help minimize potential negative consequences to our recovery from infection. Actioning these four strategies can lead to safer and speedier healing:

  • Practice moderation. Avoid drinking alcohol as much as possible while on nitrofurantoin. Opt for light or non-alcoholic beverages or mocktails, and set limits for yourself when you do go out. Avoiding triggers and standing up to peer pressure are other great ways to reduce overall alcohol consumption. 
  • Monitor symptoms. Tracking your alcohol consumption helps you connect any dots between your drinking and symptoms, and it can help you communicate clearly with your physician. They can offer personalized advice based on your unique health needs.
  • Adhere to the medication cycle. Completing the entire cycle of antibiotics is necessary to ensure the best chance of completely eliminating the infection. Always take your medication as prescribed. If you know we’ll be out for the night and may forget to take it the morning after, it’s helpful to set an alarm or designate an accountability buddy.
  • Maintain nutrition and hydration. Proper nutrition and hydration are key for fighting off infections. If you’re planning to drink, prioritize eating a balanced meal that supports your liver and consider giving your liver a boost with a next-day liver detox drink. Maintain hydration by keeping a water bottle handy and supplementing with electrolytes.

Moving Forward

Macrobid and nitrofurantoin are short-term antibiotics that help to treat UTIs. Although not immediately dangerous, mixing alcohol and Macrobid puts unnecessary stress on our body and increases the possibility of unpleasant symptoms and complications.

If we choose to drink, implementing mindful drinking practices can minimize risks. Keeping these strategies in our back pocket can be helpful for practicing safe alcohol consumption in other scenarios as well. Here’s to a healthy tomorrow!

You’ve just been prescribed Macrobid, and you’re ready to finally kick this infection. Especially because tomorrow is your friend’s birthday party — and it’s going to be lit! You’re looking forward to having a few drinks, and you’ve already preordered your Uber for the drive home.

A quick glance at the leaflet from the pharmacy says you should be okay to drink on Macrobid, so you don’t need to worry — right?

Just because we can eat all the cookies in the cookie jar doesn’t mean it’s healthy to do so. Even though there aren’t any direct interactions between alcohol and Macrobid, there can be adverse effects to mixing the two. Let’s examine these effects further; well-informed decisions require well-formed knowledge!

What Is Macrobid?

woman holding a glass of alcohol and a pill

Macrobid (a.k.a., nitrofurantoin) is an antibiotic that is used to treat bacterial infections, most commonly urinary tract infections (UTIs). The antibiotic is different from other, more common antibiotics; it collects in the urine, making it a good choice for infections involving the lower urinary tract. It’s one of the most common prescriptions in the United States with roughly 4 million prescriptions per year. Macrobid only works against bacterial infections, not viral infections of the urinary tract (such as BK virus, adenovirus, or herpes simplex virus). 

The medication starts working within a couple of hours, and it is typically taken for 5-7 days. Several side effects are associated with Macrobid:

  • Nausea 
  • Headache
  • Dizziness
  • Joint or muscle pain
  • Swelling
  • Shortness of breath
  • General discomfort (malaise)

In very rare cases, Macrobid can cause damage to lungs, liver, and nerves. However, Macrobid is regarded as generally safe to use.

Are Macrobid and Nitrofurantoin the Same Thing?

Macrobid is the brand-name version of the generic drug nitrofurantoin. Brand-name Macrobid contains nitrofurantoin in both slow-release macrocrystal form and a quick-acting liquid monohydrate form. Together, this attacks an acute UTI from two angles. (Other nitrofurantoin formulations contain only macrocrystals and are usually used as a preventative to avoid UTIs.)

Our doctor will prescribe the appropriate form of nitrofurantoin to treat our specific circumstances. The most important thing is to take it as prescribed and read all directions and warning labels.

Systemic Effects of Macrobid and Alcohol

So, can you drink alcohol while taking nitrofurantoin? The answer is complicated. Although Macrobid and alcohol don't have any direct interactions, mixing them can interfere with the drug’s effectiveness, damage our liver, and slow down our recovery from infection.

  • Liver metabolization. Most drugs are metabolized by the liver — including Macrobid. Using both at the same time can stress out the liver and inhibit its ability to effectively eliminate the toxic byproducts of alcohol metabolism, possibly leaving us with a nasty hangover. Proper liver function is crucial in helping break down toxins at an appropriate rate to prevent them from causing negative effects on other organs and systems in our body.
  • Decreased immune function. Our immune system’s main role is to help fight infection and keep us healthy. When recovering from a UTI, a strong immune system is critical to eliminating the infection because the Macrobid is only a boost to our body’s natural bacteria-fighting power. Alcohol dampens the function of our immune system, taking away precious resources and prolonging recovery. 

  • Dehydration. Alcohol is a diuretic, meaning it makes us pee. Hydration is essential for treating a UTI because peeing regularly prevents further bacteria growth. While alcohol can cause us to urinate a lot in the short term, the result is that we’re left dehydrated and playing catchup to restore our fluid levels.
  • Medication adherence. Nitrofurantoin is prescribed for 5-7 days to ensure the infection is completely eliminated. Although symptoms may start to go away before then, the entire round of antibiotics is recommended for full effectiveness. Alcohol is correlated with decreased inhibitions and impacted judgment. Research has shown that drinking may influence a patient's adherence to taking daily medication, which may increase the risk of UTI recurrence. 

Despite no acute interactions, it’s clear that alcohol can still interfere with nitrofurantoin. While the above conditions can complicate UTI treatment, there are also some ways that .

Risks of Drinking Alcohol While On Macrobid

Risks of Drinking on Nitrofurantoin

To make more mindful decisions when drinking while on nitrofurantoin, it’s important to know what we may be getting into:

  • Increased side effects. UTIs are painful and unpleasant. Alcohol can further exacerbate symptoms, increase side effects from medication, and heighten the risk of experiencing hangover symptoms — compounding the uncomfortable experience. Choosing to drink while on nitrofurantoin is like holding up a big welcome sign to usher in unpleasant symptoms such as nausea, vomiting, headache, and stomach pain.
  • Decreased effectiveness. Alcohol’s impact on our immune system and hormones can affect our body’s ability to fight against infection — indirectly dampening the effectiveness of nitrofurantoin.
  • Risk of liver damage. Prolonged and excessive drinking is associated with liver damage and disease. When our liver is in overdrive trying to break down alcohol and other drugs in our system, it’s less efficient at eliminating toxic substances that cause damage to our cells and organs. While on nitrofurantoin, alcohol can create the perfect storm that may lead to liver damage or disease.

We may have missed the tiny print on the back of the bottle warning us of these potential risks. If we’ve already had a drink or two while taking nitrofurantoin, should we be concerned?

What To Do If You’ve Already Consumed Alcohol With Nitrofurantoin

First of all: don’t panic! You’re going to be okay; plus, high stress levels can negatively impact recovery and lead us to make rash decisions through black-and-white thinking

Avoid further drinking and make sure to continue taking the medication as directed. Immediate symptoms may not show up after drinking, and it shouldn’t cause any immediate risk to health. If symptoms do arise, keep track of them and reach out to a doctor.

How Long After Taking Nitrofurantoin Can You Drink Alcohol?

Drinking while on nitrofurantoin isn’t recommended, but what about after? Similar to drinking while on the medication, drinking after finishing treatment may not cause immediate risks or direct impacts. However, it’s recommended to wait at least 48 hours after finishing nitrofurantoin to resume drinking.

Even after finishing the round of antibiotics, there’s still the chance of a lingering infection. Take it easy on alcohol — or better yet, avoid it all together — for a week or two after finishing treatment. This allows the body a better chance to fight off any infection that could still be present. Drinking immediately after finishing treatment will not cause any significant dangers (beyond the regular dangers of alcohol), but making intentional choices sets us up for the most successful and safe recovery.

Approaching Safe Consumption of Nitrofurantoin and Alcohol 

If we choose to drink, mindful practices can help minimize potential negative consequences to our recovery from infection. Actioning these four strategies can lead to safer and speedier healing:

  • Practice moderation. Avoid drinking alcohol as much as possible while on nitrofurantoin. Opt for light or non-alcoholic beverages or mocktails, and set limits for yourself when you do go out. Avoiding triggers and standing up to peer pressure are other great ways to reduce overall alcohol consumption. 
  • Monitor symptoms. Tracking your alcohol consumption helps you connect any dots between your drinking and symptoms, and it can help you communicate clearly with your physician. They can offer personalized advice based on your unique health needs.
  • Adhere to the medication cycle. Completing the entire cycle of antibiotics is necessary to ensure the best chance of completely eliminating the infection. Always take your medication as prescribed. If you know we’ll be out for the night and may forget to take it the morning after, it’s helpful to set an alarm or designate an accountability buddy.
  • Maintain nutrition and hydration. Proper nutrition and hydration are key for fighting off infections. If you’re planning to drink, prioritize eating a balanced meal that supports your liver and consider giving your liver a boost with a next-day liver detox drink. Maintain hydration by keeping a water bottle handy and supplementing with electrolytes.

Moving Forward

Macrobid and nitrofurantoin are short-term antibiotics that help to treat UTIs. Although not immediately dangerous, mixing alcohol and Macrobid puts unnecessary stress on our body and increases the possibility of unpleasant symptoms and complications.

If we choose to drink, implementing mindful drinking practices can minimize risks. Keeping these strategies in our back pocket can be helpful for practicing safe alcohol consumption in other scenarios as well. Here’s to a healthy tomorrow!

Alcohol and Medications
2024-04-26 9:00
Alcohol and Medications
Can You Drink on Mucinex?
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Taking Mucinex this cold season and wondering if drinking on Mucinex is a bad idea? Find out why the two are not a great mix in our latest blog!

17 min read

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Mucinex and Alcohol: The Risks

Mucinex used to run commercials featuring “Mr. Mucus,” the lovable green and slimy antihero that the sinus-saving, cold-clearing medicine promises to sweep out of your nasal passages. So when you wake up clogged up and groggy, your eyes stinging and your m’s sounding like b’s when you talk, reaching for that trusty bottle of Mucinex can bring much-needed relief. But then you remember that beer you had before bed. Is it safe to take Mucinex after drinking? Should you wait? Let’s find out more!

What Is Mucinex and What Is It Used For?

As Mr. Mucus shows us, Mucinex is quite the multitasker. The active ingredient, guaifenesin, helps loosen up mucus to flush it out of the body.

A woman sitting on a bed, blowing her nose into a tissue

While it might sound like something that came out of test tubes in the lab, guaifenesin is as natural as it gets. According to The Encyclopedia of Toxicology, it was “originally derived from the guaiac tree and used by Native Americans for health purposes.” Having caught on to its medicinal magic, scientists began to synthesize it in 1912. However, it took 77 years for the FDA to officially approve Mucinex in 1989 and another 15 for Mr. Mucus to officially enter the scene as its mascot in 2004.

From pills to syrups, Mucinex comes in all shapes and sizes. It also “plays well” with other meds and is often combined with antihistamines, cough suppressants, and decongestants.

While Mucinex is a very popular version of guaifenesin (thanks in part to Mr. Mucus and his marketing power), the medication comes under many other brand aliases:

  • Air Power (the dairy-free, vegan version produced by Nature’s Way)
  • Cough Out (just guaifenesin under a different name) 
  • Equaline Tussin and Equate Tussin (also containing dextromethorphan)
  • Good Neighbor Pharmacy Tussin (a “neighborly” mix of dextromethorphan hydrobromide, guaifenesin, and phenylephrine hydrochloride)
  • Good Sense Tussin (guaifenesin with dextromethorphan)
  • Guiatuss (combined with codeine, available by prescription)
  • Leader Adult Tussin (another guaifenesin and dextromethorphan combo) 
  • Leader Mucus Relief (a mix of guaifenesin, hypromellose, magnesium stearate, maltodextrin, microcrystalline cellulose, polyethylene glycol, povidone, silicon dioxide, sodium starch glycolate, stearic acid)
  • Liqufruta (herbal garlic cough syrup with guaifenesin)
  • Refenesen Chest Congestion Relief (also contains phenylephrine)
  • Robitussin Chest Congestion (also contains dextromethorphan)
  • Siltussin (a liquid form of guaifenesin with a twist — this one tastes like strawberries)
  • Wal Tussin (Walgreens’ take on the dextromethorphan-guaifenesin combo)

Many other pharmacies and stores might have their own brand as well; it’s a tried-and-true remedy for congestion!

Can You Drink on Mucinex?

In short, alcohol and Mucinex are not a great mix. To understand why, let’s first take a look at the common side effects Mucinex is known for:

  • Nausea and vomiting. Mucinex can irritate the stomach lining, making us feel queasy or even causing us to throw up. 
  • Drowsiness. Like many other cold medications, Mucinex can make us nod off or feel a bit more drowsy than usual.
  • Headaches. Another pesky side effect some folks experience is headaches. Hint: staying hydrated can help!
  • Dizziness. Mucinex can affect our inner ear, temporarily throwing us off balance. It could also tweak our blood pressure a bit, causing minor fluctuations. Neither of these is a huge deal — it’s a bit like the feeling of standing up too quickly.


None of these are a huge deal on their own, but what happens when we mix them with alcohol? Let’s find out why combining the two is asking for trouble.

Alcohol and Mucinex: Worsened Side Effects 

Now that we have an idea of the side effects of Mucinex, we can see that adding alcohol to the mix isn’t the best idea. When we drink alcohol alongside Mucinex, we run the risk of worsening side effects: 

  • Sedation struggles. Alcohol is a known depressant, which slows down our central nervous system (CNS). And while guaifenesin’s CNS effects with guaifenesin are minimal, the mix could potentially make us extra drowsy and dizzy.
  • Hefty headaches. Both alcohol and Mucinex can cause headaches, so putting the two together is asking for trouble. As if having a cold doesn’t dehydrate us enough, alcohol can cause further dehydration and, consequently, headaches. Alcohol also causes vasodilation, increasing blood flow (and pressure) to the brain. The buildup of acetaldehyde — a toxic byproduct of alcohol metabolism — turns up the headache dial even more.
  • Tummy troubles. We know that Mucinex can be hard on the stomach, and alcohol is even worse. Alcohol amps up stomach acid production, leading to irritation, nausea, and acid reflux. Over time, it could cause problems such as gastritis or stomach ulcers! (For a deeper look, check out our blog: “5 Ways Alcohol Affects the Stomach and Digestive System.”)

All of these symptoms can only make us more miserable when we are sick. But there are even more dangers to drinking alcohol with Mucinex. Let’s take a look. 

Alcohol, Mucinex, and the Liver 

Guaifenesin and alcohol are both metabolized by the liver, which can get overwhelmed by the double task of digesting both. Even worse, overtasking the liver can lead to a buildup of acetaldehyde, which contributes to hangovers and can even cause serious illnesses in the long run.

Beyond Guaifenesin: Additional Ingredients in Mucinex

Another potential pitfall with combining Mucinex and alcohol? Guaifenesin may not be the only med in the mix. Many formulas that contain it have other ingredients to tackle all those additional cold-related symptoms, such as body aches and pains, cough, headaches, and sinus pain. And once again, most of them are not booze-friendly either: 

  • Dextromethorphan (DXM). According to WebMD, DXM is used to ease cough caused by infections of the air passages triggered by sinusitis or colds. It’s often included in Mucinex as one of the ingredients. 

    The problem with mixing DXM and alcohol? According to Drugs.com, on the lighter side, we could be looking at dizziness, drowsiness, and concentration difficulties. And if things get more serious, there’s a chance of more serious “impairment in thinking and judgment.”
  • Acetaminophen. This one is a bad match for alcohol as well. The liver metabolizes both, so combining the two could lead to toxicity. (For more insight into liver damage from alcohol, take a look at “How Much Alcohol Causes Liver Damage?”).
  • Pseudoephedrine and phenylephrine. These two are great at helping us breathe more easily, but together with alcohol, pseudoephedrine in particular can be bad news. As a central nervous stimulant, it clashes with the depressant effects of booze and strains the heart. Moreover, the dizziness caused by all three — guaifenesin, pseudoephedrine, and alcohol — is a trip-and-fall waiting to happen, especially when we’re already under the weather.

If we’re nursing a cold, it’s better to avoid alcohol altogether. It will not only keep us safe but help us recover faster!

Get Well Later: Alcohol, Mucinex, and the Immune System

Finally, mixing alcohol and Mucinex doesn’t do us any favors when it comes to the reason we’re taking Mucinex in the first place.

For one thing, alcohol can throw a wrench in the workings of our immune system and isn’t the best ally in recovery from illness in general. (For more details, take a look at our blog “Alcohol's Impact on the Immune System.”)

Moreover, alcohol is a notorious diuretic that inhibits the release of the hormone in charge of telling our kidneys to hold on to water. And while Mucinex isn’t dehydrating per se, the cold itself is. So, adding booze to the mix dries up our body — and especially our sensitive nasal passages — even more.

How Many Hours After Taking Mucinex Should I Wait To Drink Alcohol? 

Doctors say to wait at least 12 hours to be safe. But if you have any concerns or are taking additional medications, always check with yours! They know you best and will be able to offer advice that’s tailored to your needs and situation.

How much alcohol is too much? Michigan State professor and physician James J. Galligan said in an interview with Self, “There are many drugs that can interact with alcohol resulting in loss of memory and consciousness … Even one or two drinks can interact with some drugs to produce severe intoxication and potentially loss of consciousness in some people.”

Another physician, David Cutler, clarifies that having a single drink probably won’t be the end of the world. Still, it’s not a great idea: “The problem is that people often think that if they feel OK after having one drink, they can have two, and things go downhill from there. Also, just because you’re probably OK if you stick with one drink doesn’t mean you can’t have a bad reaction. ‘It’s not that you’ll never have one, it’s just unlikely.’”

Tips To Stay Safe and Get Well When Taking Mucinex

Tips To Stay Safe and Get Well

To help you stay safe while taking Mucinex — as well as after you recover — consider these tips:

  1. Watch your intake. If alcohol has become a frequent habit, taking a break might seem a bit tough at first, but look at it as an opportunity to explore a healthier lifestyle! It’s best to avoid mixing alcohol and Mucinex to avoid a potentially dangerous mix of side effects, among other reasons.
  2. Hydrate. Hydration is crucial every day, but it’s especially important when we’re sick. Dehydration can also make Mucinex side effects such as nausea and headaches worse, so drink up!
  3. Nourish your body. Remember how your mom told you to “feed a cold”? Nutritious food is always important, but it’s especially crucial when we’re under the weather. Chicken soup is an old favorite for a reason — the warm brew is soothing for the throat and sinuses, while the chicken provides some much-needed energy. And those vitamin-packed veggies? An added boost for your immune system!
  4. Try some ginger tea. Ginger tea is known for its anti-nausea properties, plus it’s soothing! So if your cold (and Mucinex) are making you queasy, this time-tested cure could work wonders!
  5. Take time to heal. Take this time as an opportunity to enjoy some booze-free downtime. There are plenty of relaxing activities to enjoy — maybe a project (such as putting together a photo collage) that has been on the back burner for a while. Or a feel-good show marathon if you’re not up for getting up from the couch. Creative, comforting activities that feel like a “treat” serve as natural ways to release dopamine, keeping those alcohol cravings at bay.

Once you’re feeling better, you’ll be glad that alcohol didn’t mess with the healing process. Plus, you now have some tools to help you navigate alcohol-related situations well into the post-Mucinex future.

Respecting Your Future Self

In the end, we all get a visit from Mr. Mucus sometimes — it’s part of life. However, adding alcohol to the mix will only make the situation worse. As writer A.J. Jacobs observes in Drop Dead Healthy: One Man's Humble Quest for Bodily Perfection, “The key to making healthy decisions is to respect your future self. Honor him or her. Treat him or her like you would treat a friend or a loved one.” Let’s appreciate the body that does so much for us and give it the love and care it deserves — our future self will thank us!

Mucinex and Alcohol: The Risks

Mucinex used to run commercials featuring “Mr. Mucus,” the lovable green and slimy antihero that the sinus-saving, cold-clearing medicine promises to sweep out of your nasal passages. So when you wake up clogged up and groggy, your eyes stinging and your m’s sounding like b’s when you talk, reaching for that trusty bottle of Mucinex can bring much-needed relief. But then you remember that beer you had before bed. Is it safe to take Mucinex after drinking? Should you wait? Let’s find out more!

What Is Mucinex and What Is It Used For?

As Mr. Mucus shows us, Mucinex is quite the multitasker. The active ingredient, guaifenesin, helps loosen up mucus to flush it out of the body.

A woman sitting on a bed, blowing her nose into a tissue

While it might sound like something that came out of test tubes in the lab, guaifenesin is as natural as it gets. According to The Encyclopedia of Toxicology, it was “originally derived from the guaiac tree and used by Native Americans for health purposes.” Having caught on to its medicinal magic, scientists began to synthesize it in 1912. However, it took 77 years for the FDA to officially approve Mucinex in 1989 and another 15 for Mr. Mucus to officially enter the scene as its mascot in 2004.

From pills to syrups, Mucinex comes in all shapes and sizes. It also “plays well” with other meds and is often combined with antihistamines, cough suppressants, and decongestants.

While Mucinex is a very popular version of guaifenesin (thanks in part to Mr. Mucus and his marketing power), the medication comes under many other brand aliases:

  • Air Power (the dairy-free, vegan version produced by Nature’s Way)
  • Cough Out (just guaifenesin under a different name) 
  • Equaline Tussin and Equate Tussin (also containing dextromethorphan)
  • Good Neighbor Pharmacy Tussin (a “neighborly” mix of dextromethorphan hydrobromide, guaifenesin, and phenylephrine hydrochloride)
  • Good Sense Tussin (guaifenesin with dextromethorphan)
  • Guiatuss (combined with codeine, available by prescription)
  • Leader Adult Tussin (another guaifenesin and dextromethorphan combo) 
  • Leader Mucus Relief (a mix of guaifenesin, hypromellose, magnesium stearate, maltodextrin, microcrystalline cellulose, polyethylene glycol, povidone, silicon dioxide, sodium starch glycolate, stearic acid)
  • Liqufruta (herbal garlic cough syrup with guaifenesin)
  • Refenesen Chest Congestion Relief (also contains phenylephrine)
  • Robitussin Chest Congestion (also contains dextromethorphan)
  • Siltussin (a liquid form of guaifenesin with a twist — this one tastes like strawberries)
  • Wal Tussin (Walgreens’ take on the dextromethorphan-guaifenesin combo)

Many other pharmacies and stores might have their own brand as well; it’s a tried-and-true remedy for congestion!

Can You Drink on Mucinex?

In short, alcohol and Mucinex are not a great mix. To understand why, let’s first take a look at the common side effects Mucinex is known for:

  • Nausea and vomiting. Mucinex can irritate the stomach lining, making us feel queasy or even causing us to throw up. 
  • Drowsiness. Like many other cold medications, Mucinex can make us nod off or feel a bit more drowsy than usual.
  • Headaches. Another pesky side effect some folks experience is headaches. Hint: staying hydrated can help!
  • Dizziness. Mucinex can affect our inner ear, temporarily throwing us off balance. It could also tweak our blood pressure a bit, causing minor fluctuations. Neither of these is a huge deal — it’s a bit like the feeling of standing up too quickly.


None of these are a huge deal on their own, but what happens when we mix them with alcohol? Let’s find out why combining the two is asking for trouble.

Alcohol and Mucinex: Worsened Side Effects 

Now that we have an idea of the side effects of Mucinex, we can see that adding alcohol to the mix isn’t the best idea. When we drink alcohol alongside Mucinex, we run the risk of worsening side effects: 

  • Sedation struggles. Alcohol is a known depressant, which slows down our central nervous system (CNS). And while guaifenesin’s CNS effects with guaifenesin are minimal, the mix could potentially make us extra drowsy and dizzy.
  • Hefty headaches. Both alcohol and Mucinex can cause headaches, so putting the two together is asking for trouble. As if having a cold doesn’t dehydrate us enough, alcohol can cause further dehydration and, consequently, headaches. Alcohol also causes vasodilation, increasing blood flow (and pressure) to the brain. The buildup of acetaldehyde — a toxic byproduct of alcohol metabolism — turns up the headache dial even more.
  • Tummy troubles. We know that Mucinex can be hard on the stomach, and alcohol is even worse. Alcohol amps up stomach acid production, leading to irritation, nausea, and acid reflux. Over time, it could cause problems such as gastritis or stomach ulcers! (For a deeper look, check out our blog: “5 Ways Alcohol Affects the Stomach and Digestive System.”)

All of these symptoms can only make us more miserable when we are sick. But there are even more dangers to drinking alcohol with Mucinex. Let’s take a look. 

Alcohol, Mucinex, and the Liver 

Guaifenesin and alcohol are both metabolized by the liver, which can get overwhelmed by the double task of digesting both. Even worse, overtasking the liver can lead to a buildup of acetaldehyde, which contributes to hangovers and can even cause serious illnesses in the long run.

Beyond Guaifenesin: Additional Ingredients in Mucinex

Another potential pitfall with combining Mucinex and alcohol? Guaifenesin may not be the only med in the mix. Many formulas that contain it have other ingredients to tackle all those additional cold-related symptoms, such as body aches and pains, cough, headaches, and sinus pain. And once again, most of them are not booze-friendly either: 

  • Dextromethorphan (DXM). According to WebMD, DXM is used to ease cough caused by infections of the air passages triggered by sinusitis or colds. It’s often included in Mucinex as one of the ingredients. 

    The problem with mixing DXM and alcohol? According to Drugs.com, on the lighter side, we could be looking at dizziness, drowsiness, and concentration difficulties. And if things get more serious, there’s a chance of more serious “impairment in thinking and judgment.”
  • Acetaminophen. This one is a bad match for alcohol as well. The liver metabolizes both, so combining the two could lead to toxicity. (For more insight into liver damage from alcohol, take a look at “How Much Alcohol Causes Liver Damage?”).
  • Pseudoephedrine and phenylephrine. These two are great at helping us breathe more easily, but together with alcohol, pseudoephedrine in particular can be bad news. As a central nervous stimulant, it clashes with the depressant effects of booze and strains the heart. Moreover, the dizziness caused by all three — guaifenesin, pseudoephedrine, and alcohol — is a trip-and-fall waiting to happen, especially when we’re already under the weather.

If we’re nursing a cold, it’s better to avoid alcohol altogether. It will not only keep us safe but help us recover faster!

Get Well Later: Alcohol, Mucinex, and the Immune System

Finally, mixing alcohol and Mucinex doesn’t do us any favors when it comes to the reason we’re taking Mucinex in the first place.

For one thing, alcohol can throw a wrench in the workings of our immune system and isn’t the best ally in recovery from illness in general. (For more details, take a look at our blog “Alcohol's Impact on the Immune System.”)

Moreover, alcohol is a notorious diuretic that inhibits the release of the hormone in charge of telling our kidneys to hold on to water. And while Mucinex isn’t dehydrating per se, the cold itself is. So, adding booze to the mix dries up our body — and especially our sensitive nasal passages — even more.

How Many Hours After Taking Mucinex Should I Wait To Drink Alcohol? 

Doctors say to wait at least 12 hours to be safe. But if you have any concerns or are taking additional medications, always check with yours! They know you best and will be able to offer advice that’s tailored to your needs and situation.

How much alcohol is too much? Michigan State professor and physician James J. Galligan said in an interview with Self, “There are many drugs that can interact with alcohol resulting in loss of memory and consciousness … Even one or two drinks can interact with some drugs to produce severe intoxication and potentially loss of consciousness in some people.”

Another physician, David Cutler, clarifies that having a single drink probably won’t be the end of the world. Still, it’s not a great idea: “The problem is that people often think that if they feel OK after having one drink, they can have two, and things go downhill from there. Also, just because you’re probably OK if you stick with one drink doesn’t mean you can’t have a bad reaction. ‘It’s not that you’ll never have one, it’s just unlikely.’”

Tips To Stay Safe and Get Well When Taking Mucinex

Tips To Stay Safe and Get Well

To help you stay safe while taking Mucinex — as well as after you recover — consider these tips:

  1. Watch your intake. If alcohol has become a frequent habit, taking a break might seem a bit tough at first, but look at it as an opportunity to explore a healthier lifestyle! It’s best to avoid mixing alcohol and Mucinex to avoid a potentially dangerous mix of side effects, among other reasons.
  2. Hydrate. Hydration is crucial every day, but it’s especially important when we’re sick. Dehydration can also make Mucinex side effects such as nausea and headaches worse, so drink up!
  3. Nourish your body. Remember how your mom told you to “feed a cold”? Nutritious food is always important, but it’s especially crucial when we’re under the weather. Chicken soup is an old favorite for a reason — the warm brew is soothing for the throat and sinuses, while the chicken provides some much-needed energy. And those vitamin-packed veggies? An added boost for your immune system!
  4. Try some ginger tea. Ginger tea is known for its anti-nausea properties, plus it’s soothing! So if your cold (and Mucinex) are making you queasy, this time-tested cure could work wonders!
  5. Take time to heal. Take this time as an opportunity to enjoy some booze-free downtime. There are plenty of relaxing activities to enjoy — maybe a project (such as putting together a photo collage) that has been on the back burner for a while. Or a feel-good show marathon if you’re not up for getting up from the couch. Creative, comforting activities that feel like a “treat” serve as natural ways to release dopamine, keeping those alcohol cravings at bay.

Once you’re feeling better, you’ll be glad that alcohol didn’t mess with the healing process. Plus, you now have some tools to help you navigate alcohol-related situations well into the post-Mucinex future.

Respecting Your Future Self

In the end, we all get a visit from Mr. Mucus sometimes — it’s part of life. However, adding alcohol to the mix will only make the situation worse. As writer A.J. Jacobs observes in Drop Dead Healthy: One Man's Humble Quest for Bodily Perfection, “The key to making healthy decisions is to respect your future self. Honor him or her. Treat him or her like you would treat a friend or a loved one.” Let’s appreciate the body that does so much for us and give it the love and care it deserves — our future self will thank us!

Alcohol and Medications
2024-04-25 9:00
Alcohol and Medications
Can You Drink Alcohol While Taking Omeprazole?
This is some text inside of a div block.

Struggling with heartburn? Taking Prilosec? Planning on drinking this weekend? Here’s what you need to know about omeprazole and alcohol.

10 min read

Drink Less and Thrive With Reframe

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!

Read Full Article  →

You just got back from lunch break, and you’ve got that familiar fire in your chest and bitter taste in your mouth. And you don’t dare bend over to pick up that paper you just dropped for fear your lunch will resurface. Ugh — heartburn again. It seems like you can’t eat or drink anything these days without instant regret. 

Your doctor recommended Prilosec, and it’s been helping so far, but you have a wedding to attend this weekend. Can you take omeprazole with alcohol? 

What Is Omeprazole? 

Omeprazole is a medicine —a proton pump inhibitor (PPI) to be precise — used to reduce the amount of acid in the stomach. Often known by the brand name Prilosec, omeprazole is used to treat frequent heartburn or conditions where too much acid is produced in the stomach: 

  • Gastric and duodenal ulcers 
  • Erosive esophagitis
  • Gastroesophageal reflux disease (GERD)
  • Gastroparesis 

In these conditions, there is too much acid in the stomach, and that acid is pushed from the stomach to the esophagus, causing us some unpleasant symptoms.

As a PPI, omeprazole slows gastric acid secretion by inhibiting an enzyme in the final step of the stomach’s acid secretion process. Does this mean that if we take PPIs we won’t have any stomach acid? No, PPIs only inhibit 66-80% of acid output in our stomach. Having less acid in our stomach can help reduce the instances of GERD, help our esophagus heal if we have erosive esophagitis, or rid us of gastric ulcers. 

Side Effects of Omeprazole

Prilosec is available to buy over-the-counter; however, it is not recommended to take it for more than 14 days without consulting a doctor first. While it is generally safe and effective, some people do experience side effects: 


  • Headaches
  • Abdominal pain
  • Diarrhea
  • Nausea and vomiting 

Extreme doses of 2400 mg (120 times higher than the recommended dose) can lead to more troublesome side effects: 

  • Confusion
  • Drowsiness
  • Tachycardia
  • Blurred vision
  • Diaphoresis 

These symptoms are typically short-lived and don’t cause serious harm, but it is always safest to stick to the recommended dose on the box. 

How To Drink Safely While on Omeprazole

Omeprazole and Alcohol Interaction

From a molecular standpoint, Prilosec and alcohol do not specifically interact. However, as we learned above, alcohol can make our stomach produce more acid. If we are taking omeprazole, we are likely trying to reduce the acid in our stomach, so drinking alcohol may counteract the purpose of the medication. Essentially, alcohol can worsen our underlying problem of having too much stomach acid. 

Furthermore, alcohol and omeprazole share side effects that can be heightened if we use them at the same time. For instance, both can cause headaches, dizziness, upset stomach, and nausea. 

So we know there are problematic interactions between Prilosec and alcohol, but the question remains: can we drink alcohol with omeprazole? 

Can You Drink Alcohol While Taking Omeprazole? 

The short answer is yes — there are no immediate dangers to drinking alcohol while taking omeprazole as there would be with sleeping pills. Drinking while on Prilosec doesn’t increase our chances of having severe side effects or an overdose of alcohol. However, most medical professionals suggest not drinking while on omeprazole since it can make our stomach issues worse. In the long run, continuously combining the two can lead to greater challenges:

  • Worsened acid reflux 
  • Increased chances of liver disease, injury, or cancer
  • Magnesium deficiency 

So, if we are on omeprazole and we want to drink, how long should we wait between the two of them? 

There is no straightforward answer, but we are supposed to take omeprazole 30-60 minutes before we eat. Likewise, we should wait at least 30-60 minutes before or after drinking alcohol.

How To Drink Alcohol Safely While on Prilosec

It is not recommended to drink alcohol while on Prilosec, but there is no risk to our immediate health if we do. Still, there are precautions we can take to drink alcohol safely while on omeprazole:

  • Drink in moderation. Whether you’re on omeprazole or not, this is always a good guideline.
  • Avoid spicy foods and carbonated drinks. Both can make our stomach acid worse.
  • Take a break from alcohol. If you are omeprazole for the 14-day, over-the-counter dose, hold off on alcohol while you get your acid production under control. 
  • Choose your booze carefully. Certain types of alcohol are less acidic than others. Generally, the higher the alcohol content, the worse we may react to it. A light beer may be better than a stronger spirit such as whiskey or scotch. Highly acidic drinks like ciders, white wines, and citrus cocktails can be harder on the stomach. 

The bottom line is that drinking alcohol while on omeprazole can make our acid reflux symptoms worse. If you’re experiencing daily discomfort due to heartburn, it is best to avoid alcohol altogether. 

The Bottom Line 

Ultimately, drinking alcohol while on omeprazole is safe but not recommended. There is no immediate risk of developing severe side effects or overdose, but if we are heavy drinkers and on PPIs long term, we are at greater risk for developing liver disease. Consult your prescribing physician before drinking alcohol if you are on Omeprazole for a chronic condition.

You just got back from lunch break, and you’ve got that familiar fire in your chest and bitter taste in your mouth. And you don’t dare bend over to pick up that paper you just dropped for fear your lunch will resurface. Ugh — heartburn again. It seems like you can’t eat or drink anything these days without instant regret. 

Your doctor recommended Prilosec, and it’s been helping so far, but you have a wedding to attend this weekend. Can you take omeprazole with alcohol? 

What Is Omeprazole? 

Omeprazole is a medicine —a proton pump inhibitor (PPI) to be precise — used to reduce the amount of acid in the stomach. Often known by the brand name Prilosec, omeprazole is used to treat frequent heartburn or conditions where too much acid is produced in the stomach: 

  • Gastric and duodenal ulcers 
  • Erosive esophagitis
  • Gastroesophageal reflux disease (GERD)
  • Gastroparesis 

In these conditions, there is too much acid in the stomach, and that acid is pushed from the stomach to the esophagus, causing us some unpleasant symptoms.

As a PPI, omeprazole slows gastric acid secretion by inhibiting an enzyme in the final step of the stomach’s acid secretion process. Does this mean that if we take PPIs we won’t have any stomach acid? No, PPIs only inhibit 66-80% of acid output in our stomach. Having less acid in our stomach can help reduce the instances of GERD, help our esophagus heal if we have erosive esophagitis, or rid us of gastric ulcers. 

Side Effects of Omeprazole

Prilosec is available to buy over-the-counter; however, it is not recommended to take it for more than 14 days without consulting a doctor first. While it is generally safe and effective, some people do experience side effects: 


  • Headaches
  • Abdominal pain
  • Diarrhea
  • Nausea and vomiting 

Extreme doses of 2400 mg (120 times higher than the recommended dose) can lead to more troublesome side effects: 

  • Confusion
  • Drowsiness
  • Tachycardia
  • Blurred vision
  • Diaphoresis 

These symptoms are typically short-lived and don’t cause serious harm, but it is always safest to stick to the recommended dose on the box. 

How To Drink Safely While on Omeprazole

Omeprazole and Alcohol Interaction

From a molecular standpoint, Prilosec and alcohol do not specifically interact. However, as we learned above, alcohol can make our stomach produce more acid. If we are taking omeprazole, we are likely trying to reduce the acid in our stomach, so drinking alcohol may counteract the purpose of the medication. Essentially, alcohol can worsen our underlying problem of having too much stomach acid. 

Furthermore, alcohol and omeprazole share side effects that can be heightened if we use them at the same time. For instance, both can cause headaches, dizziness, upset stomach, and nausea. 

So we know there are problematic interactions between Prilosec and alcohol, but the question remains: can we drink alcohol with omeprazole? 

Can You Drink Alcohol While Taking Omeprazole? 

The short answer is yes — there are no immediate dangers to drinking alcohol while taking omeprazole as there would be with sleeping pills. Drinking while on Prilosec doesn’t increase our chances of having severe side effects or an overdose of alcohol. However, most medical professionals suggest not drinking while on omeprazole since it can make our stomach issues worse. In the long run, continuously combining the two can lead to greater challenges:

  • Worsened acid reflux 
  • Increased chances of liver disease, injury, or cancer
  • Magnesium deficiency 

So, if we are on omeprazole and we want to drink, how long should we wait between the two of them? 

There is no straightforward answer, but we are supposed to take omeprazole 30-60 minutes before we eat. Likewise, we should wait at least 30-60 minutes before or after drinking alcohol.

How To Drink Alcohol Safely While on Prilosec

It is not recommended to drink alcohol while on Prilosec, but there is no risk to our immediate health if we do. Still, there are precautions we can take to drink alcohol safely while on omeprazole:

  • Drink in moderation. Whether you’re on omeprazole or not, this is always a good guideline.
  • Avoid spicy foods and carbonated drinks. Both can make our stomach acid worse.
  • Take a break from alcohol. If you are omeprazole for the 14-day, over-the-counter dose, hold off on alcohol while you get your acid production under control. 
  • Choose your booze carefully. Certain types of alcohol are less acidic than others. Generally, the higher the alcohol content, the worse we may react to it. A light beer may be better than a stronger spirit such as whiskey or scotch. Highly acidic drinks like ciders, white wines, and citrus cocktails can be harder on the stomach. 

The bottom line is that drinking alcohol while on omeprazole can make our acid reflux symptoms worse. If you’re experiencing daily discomfort due to heartburn, it is best to avoid alcohol altogether. 

The Bottom Line 

Ultimately, drinking alcohol while on omeprazole is safe but not recommended. There is no immediate risk of developing severe side effects or overdose, but if we are heavy drinkers and on PPIs long term, we are at greater risk for developing liver disease. Consult your prescribing physician before drinking alcohol if you are on Omeprazole for a chronic condition.

Alcohol and Medications
2024-04-22 9:00
Alcohol and Medications
Can You Drink Alcohol on Bactrim?
This is some text inside of a div block.

Can you drink on Bactrim? Find out the science behind why the two might not be a great combo in our latest blog.

19 min read

Ready To Change Your Relationship With Alcohol (in Sickness or in Health)? Reframe Can Help You Cut Back or Quit!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today! 

Read Full Article  →

Can You Drink Alcohol on Bactrim?

You’ve been sick with an ear infection for days. Your head feels like there’s been nonstop road construction going on inside; you’re feeling drained (literally — must be all that stuff oozing out of your ear), and everyone’s voice sounds like they’re trapped inside a fish tank. But you just got some antibiotics from your doctor and today is a little better, so you think, hey, maybe I’ll have a beer with dinner?

But then you glance over at the bottle of Bactrim you’ve been prescribed, and it says clearly, “Don’t take with alcohol.” Now what? “Will I die if I drink on Bactrim?” Probably not, right? You text one friend who says, “Go for it! Those labels exaggerate.” But then you text your sister, and she remembers something about Bactrim being different. Who's right? Is the Bactrim and alcohol interaction truly dangerous? In short, can you drink on Bactrim?

What Is Bactrim?

a man holding a bottle of alcohol and a pills

Bactrim is an antibiotic containing sulfamethoxazole and trimethoprim. It’s used to treat bacterial infections of the middle ear, as well as urinary, respiratory, and intestinal infections. Occasionally, it might also be used to prevent some types of pneumonia.

But what are antibiotics in general? And what are they for? Let’s take a brief look.

The World of Antibiotics

Although we tend to associate antibiotics with the modern era, they’ve actually been around since ancient times. Our ancestors from ancient Egypt, Nubia, China, Serbia, Greece, and Rome all figured out that certain herbs and types of mold could cure infectious diseases. Although they didn’t understand the chemical mechanism, they put antibiotics into practice in their medicine.

Literally meaning “opposing life,” “antibiosis” was first scientifically described by Louis Pasteur and Robert Koch in 1877, when the pair laid the groundwork for the germ theory of diseases by showing that microorganisms were responsible for the spoiling of products such as milk. They found that other microorganisms (i.e., antibiotics) could inhibit the growth of their harmful counterparts.

Modern Antibiotics

As a Nature article explains, antibiotics officially came onto the scene when they were accidentally discovered by Alexander Fleming in 1928. Surprisingly, we have Fleming’s notoriously messy workspace to thank for this breakthrough! After leaving a few petri dishes with staphylococci bacteria cultures scattered around before taking off for vacation, Fleming came back to a surprising find: some of the dishes had grown a fungus (the basis for penicillin) that seemed to have killed off the disease-causing bacterial strain! (Who knew that a messy desk could set off a chain of events that revolutionized modern medicine and ultimately led to a Nobel Prize!)

Penicillin use skyrocketed in the 1940s, to the point where it could be easily purchased at any corner drug store virtually without restrictions or medical supervision. However, the heyday of antibiotics has been followed by a bit of a backlash. Scientists noticed that having too many bacteria killers out and about wiped out the good strains along with the bad, and bacteria started to adapt to be resistant to known antibiotics. Since then, it’s been a race to keep up and develop new approaches that don’t create drug-resistant strains that can’t be treated

Today, there are over 100 types of antibiotics on the market — including Bactrim — with specialized targets and various mechanisms of action. They have to be prescribed by a doctor, and it’s important to follow the instructions about their use to get the most out of the treatment without causing unintended harm.

Dangers of Mixing Alcohol and Bactrim

Bactrim: The Bigger Picture

Like any medicine, Bactrim comes with side effects. These can include nausea, vomiting, diarrhea, or loss of appetite. Sometimes, however, the side effects might get a bit more serious.

  • Muscle weakness. We may feel weak or extremely drowsy (better let someone else drive!).
  • Cognition changes. Our mood or thinking might change a bit, so if this happens (it’s not too likely) we should give ourselves a break for a few days and take it easy. We’ll be back to feeling like our usual selves soon enough!
  • Kidney damage. We might have kidney problems or end up with symptoms of low blood sugar, such as sudden sweating, shakiness, a rapid heartbeat, blurry vision, dizziness, or a tingly feeling in our hands [or] feet.
  • C. diff. In extremely rare cases, Bactrim could cause severe intestinal distress due to a bacteria called C. difficile. This condition can take a couple of weeks or months to develop, bringing on symptoms such as diarrhea that doesn't stop, abdominal or stomach pain, cramping, and bloody stools. This condition must be treated by a doctor. It can be prevented by taking probiotics or eating fermented foods such as sauerkraut, kimchi, miso paste, or yogurt.
  • Rare (but serious) side effects. Even more serious side effects include persistent headaches, kidney damage, a stiff neck, seizures, and a slow or irregular heartbeat.

But before you go swearing off Bactrim altogether, rest assured, these last few side effects are extremely rare! Bactrim has been used for decades and is generally well-tolerated by most people.


What’s Different About Bactrim?

Is there anything that makes Bactrim stand out from its counterparts? Yes! Bactrim takes a dual-action approach and gets metabolized in a way that’s a bit different. Let’s explore a bit further.

  • It has dual components. Bactrim is special because of its unique composition — it contains two different components, sulfamethoxazole and trimethoprim. Both work to inhibit the production of folic acid in bacteria, which need it for DNA synthesis and cell reproduction. However, by going for the same target in slightly different ways, sulfamethoxazole and trimethoprim deliver a double-whammy, becoming even more effective at fighting infections. 
  • It targets a variety of bacteria. Teamwork makes the dream work! By joining forces, the duo can target a wider range of bacteria than either one would be able to tackle alone.
  • It’s metabolized by the liver but excreted by the kidneys. Another important feature that sets Bactrim apart is the way it’s metabolized and excreted. While sulfamethoxazole is metabolized by the liver (more on this later!), trimethoprim is excreted by the kidneys, pretty much in its original form.

Mixing Alcohol and Antibiotics

So what about mixing antibiotics with booze: is it a no-go? Sort of okay? Or do all those bottles say “Don’t mix with alcohol” out of an abundance of (possibly unnecessary) caution?

According to a 2020 research review, there are a few possible outcomes of adding booze to the antibiotic mix.

  1. The effect the medication (or alcohol) has on the body and mind might be altered. In other words, we might get side effects or reactions we wouldn’t otherwise expect to see.
  2. The effectiveness of the antibiotic might be decreased. With alcohol in the picture, our body might not get the full benefit of the antibiotic.
  3. Toxicity might result. In a worst-case scenario, there might be a toxic interaction between the alcohol and an antibiotic. With a system that’s already compromised by illness, this is definitely not a situation we want to end up in.

The Risks of Drinking Alcohol on Bactrim

When it comes to mixing alcohol and Bactrim in particular, there are special considerations to keep in mind.

  • Bactrim metabolism. The fact that the Bactrim duo is metabolized and excreted by the liver and the kidneys is one of the main concerns. Alcohol puts a strain on both, so adding to the burden on these vital organs — especially when we’re physically not feeling our best — can spell trouble.
  • The risk of increased side effects. We’re also looking at an increased risk of side effects, especially nausea and skin reactions, since both alcohol and Bactrim can cause these on their own. Moreover, alcohol is notoriously dehydrating — an effect that can make Bactrim side effects more pronounced and unpleasant.
  • The possibility of a “disulfiram-like” reaction. Finally, there are specific effects related to the composition of Bactrim, which is similar to a medication called disulfiram that’s used to treat alcohol misuse. The sulfamethoxazole in Bactirm is related to a class of compounds present in some other antibiotics (known as sulfonylureas) that have been known to cause a “disulfiram-like reaction” by inhibiting alcohol metabolism. This reaction is extremely unpleasant and involves facial flushing, headaches, nausea, and cardiovascular effects such as heart palpitations.

(By the Way, Does “Disulfiram” Sound Familiar?)

If the word “disulfiram” sounds a bit familiar (we are talking about this in the context of alcohol, after all), you’re on the right track! Disulfiram is a popular medication prescribed to those committed to sobriety who want an extra psychological barrier to manage cravings on a daily basis.

Disulfiram inhibits certain processes in alcohol metabolism, prolonging the negative feelings associated with alcohol. Imagine the hangover from hell that doesn’t seem to end. Knowing that drinking on disulfiram will wreak all kinds of havoc can serve as a deterrent for many who are struggling with urges. By taking it at the beginning of the day, we’ve decided for ourselves that drinking today just isn’t worth it!

Still, when we’re talking about Bactrim, the risk of a disulfiram-like interaction is actually pretty low. Bactrim is not disulfiram (and is less likely to cause this particular problem than some of its antibiotic cousins), so mixing it with alcohol probably won’t send you to the hospital. Still, it’s not a great idea — and probably won’t make you feel that great. 

How Long Should You Wait to Drink After Taking Bactrim?

Doctors say that it’s best to wait at least 48 hours after completing a course of Bactrim before drinking. The rationale behind the waiting period? Allowing the body to process the antibiotic fully.

“I Drank Already, Will I Be Okay?”

Probably. If you had a drink while on Bactrim and are feeling all right, there shouldn’t be much to worry about (though it’s not a great idea to do this on a regular basis). Of course, if you have any concerns at all, don’t hesitate to get in touch with a medical professional right away!

Avoiding Booze While on Bactrim

If you’re finding it hard to stay away from alcohol while on Bactrim, here are a few tips to help.

  • Reframe the way you see the situation. Use this time as an opportunity to reexamine your relationship with alcohol. Who knows, maybe you’ll get sober-curious and want to continue trying out life beyond booze even when Bactrim is no longer in the picture!
  • Ask for help. Ask your family, friends, or roommates to keep you accountable as you heal (and, possibly, beyond!). A support team will keep your best interests in mind. Joining Reframe can help you get started! (Our 24/7 forum is like having a support team on call at all times.)
  • Explore non-alcoholic drinks. Mocktails are a great alternative to booze, and there are so many awesome ones to try! The non-alcoholic drink craze is really picking up, and now is the perfect time to explore. While many are served in bars, if you’re not up for it, it’s easy to mix them up by yourself. (A bonus? They’re way more hydrating than booze and might actually help you recover faster!). You could also try some healthy detox drinks to give your liver (and the rest of your body) a healing boost.
  • Plan your pressure-avoiding strategies. Check out some tips for social situations where people are drinking. It’s always your choice, and nobody should make you feel otherwise!

Conclusion

In the end, we’re taking Bactrim because we’re sick, and we’re probably feeling far from our best. So while having a drink on this medication probably won’t put us in immediate danger, we’re not really doing ourselves any favors either. After all, good-old ginger or chamomile tea might just do the trick when it comes to easing symptoms and allowing our body to get the rest and healing it needs.

As writer Leo Tolstoy once said, “Our body is a machine for living. It is organized for that, it is its nature. Let life go on in it unhindered and let it defend itself.” (Well, maybe with a little help from Bactrim!)

Can You Drink Alcohol on Bactrim?

You’ve been sick with an ear infection for days. Your head feels like there’s been nonstop road construction going on inside; you’re feeling drained (literally — must be all that stuff oozing out of your ear), and everyone’s voice sounds like they’re trapped inside a fish tank. But you just got some antibiotics from your doctor and today is a little better, so you think, hey, maybe I’ll have a beer with dinner?

But then you glance over at the bottle of Bactrim you’ve been prescribed, and it says clearly, “Don’t take with alcohol.” Now what? “Will I die if I drink on Bactrim?” Probably not, right? You text one friend who says, “Go for it! Those labels exaggerate.” But then you text your sister, and she remembers something about Bactrim being different. Who's right? Is the Bactrim and alcohol interaction truly dangerous? In short, can you drink on Bactrim?

What Is Bactrim?

a man holding a bottle of alcohol and a pills

Bactrim is an antibiotic containing sulfamethoxazole and trimethoprim. It’s used to treat bacterial infections of the middle ear, as well as urinary, respiratory, and intestinal infections. Occasionally, it might also be used to prevent some types of pneumonia.

But what are antibiotics in general? And what are they for? Let’s take a brief look.

The World of Antibiotics

Although we tend to associate antibiotics with the modern era, they’ve actually been around since ancient times. Our ancestors from ancient Egypt, Nubia, China, Serbia, Greece, and Rome all figured out that certain herbs and types of mold could cure infectious diseases. Although they didn’t understand the chemical mechanism, they put antibiotics into practice in their medicine.

Literally meaning “opposing life,” “antibiosis” was first scientifically described by Louis Pasteur and Robert Koch in 1877, when the pair laid the groundwork for the germ theory of diseases by showing that microorganisms were responsible for the spoiling of products such as milk. They found that other microorganisms (i.e., antibiotics) could inhibit the growth of their harmful counterparts.

Modern Antibiotics

As a Nature article explains, antibiotics officially came onto the scene when they were accidentally discovered by Alexander Fleming in 1928. Surprisingly, we have Fleming’s notoriously messy workspace to thank for this breakthrough! After leaving a few petri dishes with staphylococci bacteria cultures scattered around before taking off for vacation, Fleming came back to a surprising find: some of the dishes had grown a fungus (the basis for penicillin) that seemed to have killed off the disease-causing bacterial strain! (Who knew that a messy desk could set off a chain of events that revolutionized modern medicine and ultimately led to a Nobel Prize!)

Penicillin use skyrocketed in the 1940s, to the point where it could be easily purchased at any corner drug store virtually without restrictions or medical supervision. However, the heyday of antibiotics has been followed by a bit of a backlash. Scientists noticed that having too many bacteria killers out and about wiped out the good strains along with the bad, and bacteria started to adapt to be resistant to known antibiotics. Since then, it’s been a race to keep up and develop new approaches that don’t create drug-resistant strains that can’t be treated

Today, there are over 100 types of antibiotics on the market — including Bactrim — with specialized targets and various mechanisms of action. They have to be prescribed by a doctor, and it’s important to follow the instructions about their use to get the most out of the treatment without causing unintended harm.

Dangers of Mixing Alcohol and Bactrim

Bactrim: The Bigger Picture

Like any medicine, Bactrim comes with side effects. These can include nausea, vomiting, diarrhea, or loss of appetite. Sometimes, however, the side effects might get a bit more serious.

  • Muscle weakness. We may feel weak or extremely drowsy (better let someone else drive!).
  • Cognition changes. Our mood or thinking might change a bit, so if this happens (it’s not too likely) we should give ourselves a break for a few days and take it easy. We’ll be back to feeling like our usual selves soon enough!
  • Kidney damage. We might have kidney problems or end up with symptoms of low blood sugar, such as sudden sweating, shakiness, a rapid heartbeat, blurry vision, dizziness, or a tingly feeling in our hands [or] feet.
  • C. diff. In extremely rare cases, Bactrim could cause severe intestinal distress due to a bacteria called C. difficile. This condition can take a couple of weeks or months to develop, bringing on symptoms such as diarrhea that doesn't stop, abdominal or stomach pain, cramping, and bloody stools. This condition must be treated by a doctor. It can be prevented by taking probiotics or eating fermented foods such as sauerkraut, kimchi, miso paste, or yogurt.
  • Rare (but serious) side effects. Even more serious side effects include persistent headaches, kidney damage, a stiff neck, seizures, and a slow or irregular heartbeat.

But before you go swearing off Bactrim altogether, rest assured, these last few side effects are extremely rare! Bactrim has been used for decades and is generally well-tolerated by most people.


What’s Different About Bactrim?

Is there anything that makes Bactrim stand out from its counterparts? Yes! Bactrim takes a dual-action approach and gets metabolized in a way that’s a bit different. Let’s explore a bit further.

  • It has dual components. Bactrim is special because of its unique composition — it contains two different components, sulfamethoxazole and trimethoprim. Both work to inhibit the production of folic acid in bacteria, which need it for DNA synthesis and cell reproduction. However, by going for the same target in slightly different ways, sulfamethoxazole and trimethoprim deliver a double-whammy, becoming even more effective at fighting infections. 
  • It targets a variety of bacteria. Teamwork makes the dream work! By joining forces, the duo can target a wider range of bacteria than either one would be able to tackle alone.
  • It’s metabolized by the liver but excreted by the kidneys. Another important feature that sets Bactrim apart is the way it’s metabolized and excreted. While sulfamethoxazole is metabolized by the liver (more on this later!), trimethoprim is excreted by the kidneys, pretty much in its original form.

Mixing Alcohol and Antibiotics

So what about mixing antibiotics with booze: is it a no-go? Sort of okay? Or do all those bottles say “Don’t mix with alcohol” out of an abundance of (possibly unnecessary) caution?

According to a 2020 research review, there are a few possible outcomes of adding booze to the antibiotic mix.

  1. The effect the medication (or alcohol) has on the body and mind might be altered. In other words, we might get side effects or reactions we wouldn’t otherwise expect to see.
  2. The effectiveness of the antibiotic might be decreased. With alcohol in the picture, our body might not get the full benefit of the antibiotic.
  3. Toxicity might result. In a worst-case scenario, there might be a toxic interaction between the alcohol and an antibiotic. With a system that’s already compromised by illness, this is definitely not a situation we want to end up in.

The Risks of Drinking Alcohol on Bactrim

When it comes to mixing alcohol and Bactrim in particular, there are special considerations to keep in mind.

  • Bactrim metabolism. The fact that the Bactrim duo is metabolized and excreted by the liver and the kidneys is one of the main concerns. Alcohol puts a strain on both, so adding to the burden on these vital organs — especially when we’re physically not feeling our best — can spell trouble.
  • The risk of increased side effects. We’re also looking at an increased risk of side effects, especially nausea and skin reactions, since both alcohol and Bactrim can cause these on their own. Moreover, alcohol is notoriously dehydrating — an effect that can make Bactrim side effects more pronounced and unpleasant.
  • The possibility of a “disulfiram-like” reaction. Finally, there are specific effects related to the composition of Bactrim, which is similar to a medication called disulfiram that’s used to treat alcohol misuse. The sulfamethoxazole in Bactirm is related to a class of compounds present in some other antibiotics (known as sulfonylureas) that have been known to cause a “disulfiram-like reaction” by inhibiting alcohol metabolism. This reaction is extremely unpleasant and involves facial flushing, headaches, nausea, and cardiovascular effects such as heart palpitations.

(By the Way, Does “Disulfiram” Sound Familiar?)

If the word “disulfiram” sounds a bit familiar (we are talking about this in the context of alcohol, after all), you’re on the right track! Disulfiram is a popular medication prescribed to those committed to sobriety who want an extra psychological barrier to manage cravings on a daily basis.

Disulfiram inhibits certain processes in alcohol metabolism, prolonging the negative feelings associated with alcohol. Imagine the hangover from hell that doesn’t seem to end. Knowing that drinking on disulfiram will wreak all kinds of havoc can serve as a deterrent for many who are struggling with urges. By taking it at the beginning of the day, we’ve decided for ourselves that drinking today just isn’t worth it!

Still, when we’re talking about Bactrim, the risk of a disulfiram-like interaction is actually pretty low. Bactrim is not disulfiram (and is less likely to cause this particular problem than some of its antibiotic cousins), so mixing it with alcohol probably won’t send you to the hospital. Still, it’s not a great idea — and probably won’t make you feel that great. 

How Long Should You Wait to Drink After Taking Bactrim?

Doctors say that it’s best to wait at least 48 hours after completing a course of Bactrim before drinking. The rationale behind the waiting period? Allowing the body to process the antibiotic fully.

“I Drank Already, Will I Be Okay?”

Probably. If you had a drink while on Bactrim and are feeling all right, there shouldn’t be much to worry about (though it’s not a great idea to do this on a regular basis). Of course, if you have any concerns at all, don’t hesitate to get in touch with a medical professional right away!

Avoiding Booze While on Bactrim

If you’re finding it hard to stay away from alcohol while on Bactrim, here are a few tips to help.

  • Reframe the way you see the situation. Use this time as an opportunity to reexamine your relationship with alcohol. Who knows, maybe you’ll get sober-curious and want to continue trying out life beyond booze even when Bactrim is no longer in the picture!
  • Ask for help. Ask your family, friends, or roommates to keep you accountable as you heal (and, possibly, beyond!). A support team will keep your best interests in mind. Joining Reframe can help you get started! (Our 24/7 forum is like having a support team on call at all times.)
  • Explore non-alcoholic drinks. Mocktails are a great alternative to booze, and there are so many awesome ones to try! The non-alcoholic drink craze is really picking up, and now is the perfect time to explore. While many are served in bars, if you’re not up for it, it’s easy to mix them up by yourself. (A bonus? They’re way more hydrating than booze and might actually help you recover faster!). You could also try some healthy detox drinks to give your liver (and the rest of your body) a healing boost.
  • Plan your pressure-avoiding strategies. Check out some tips for social situations where people are drinking. It’s always your choice, and nobody should make you feel otherwise!

Conclusion

In the end, we’re taking Bactrim because we’re sick, and we’re probably feeling far from our best. So while having a drink on this medication probably won’t put us in immediate danger, we’re not really doing ourselves any favors either. After all, good-old ginger or chamomile tea might just do the trick when it comes to easing symptoms and allowing our body to get the rest and healing it needs.

As writer Leo Tolstoy once said, “Our body is a machine for living. It is organized for that, it is its nature. Let life go on in it unhindered and let it defend itself.” (Well, maybe with a little help from Bactrim!)

Alcohol and Medications
2024-04-22 9:00
Alcohol and Medications
The Risks of Mixing Dramamine and Alcohol
This is some text inside of a div block.

Can you drink on Dramamine, or is it too risky? Read about the possible dangers of this combination in our latest blog.

19 min read

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Nobody likes to feel nauseous. It’s that indescribable feeling — not quite “pain” but somehow just as bad. And often there seems to be no escape from it. Philosopher Jean-Paul Sartre dedicated a whole novel — Nausea — to the pervasive sensation. He writes, “The nausea has not left me and I don't believe it will leave me so soon; but I no longer have to bear it, it is no longer an illness or a passing fit: it is I.”

So if you tend to get nauseous — on planes, buses, that spinning teacup ride at Disney World — you probably have your travel kit stocked with over-the-counter nausea aids (if only they were around when Sartre’s protagonist was grappling with his affliction!).

But wait a second, is it okay to pop a Dramamine before knocking back a glass of wine on the plane or have a beer after you get off that bumpy bus ride? What are the dangers of mixing Dramamine and alcohol — can you drink on Dramamine at all? And what about using Dramamine for hangover-related nausea? Let’s find out more!

When Motion Makes Us Sick

a glass of alcohol next to cigarettes

Unfortunately, motion sickness is a part of life for many of us. It can show up during our daily commute to work, in the back seat of an Uber, and even on vacation trips. As scientist Natasha Tuznik tells UC Davis Health, “A study conducted in 2019 found that almost everyone has experienced or will experience motion sickness at some point in their lifetime.”

This “sickness” goes way back — in fact, the word comes from the Greek naus, meaning “ship.” These days, of course, there are many other modes of transportation that seem to conspire to ruin our transit experience.

In a study published in Ergonomics, as many as 28.4% of people surveyed reported feeling ill during a total of 110 hours of test drives that included 5 types of vehicles and 17 different drivers. Moreover, 12.8% reported experiencing nausea, while 1.7% brave participants admitted to “losing their lunch” during the experiment!

Riding in cars is part of modern life. Thankfully, so is modern science! Enter: Dramamine.

Dramamine: A Lifeline for Motion Sickness

Dramamine (Dimenhydrinate) is an antihistamine used to kick the most unpleasant symptoms of motion sickness (such as nausea, vomiting, and dizziness) right to the curb. In fact, it can even prevent them from starting in the first place!

Know Dramamine by another name? That’s quite possible. According to ScienceDirect, this trusty travel companion has many aliases:

  • Andramine (or andrumin)
  • Antemin
  • Chloranautine
  • Detensor
  • Diamarin
  • Dimenhydrinat
  • Dommanate
  • Dramaban
  • Dramarin
  • Dramyl
  • Epha (or epharetard)
  • Faston
  • Gravol
  • Nausicalm (or paranausine)
  • Travel gum (as well as travelin, travelmin, or trawell)
  • Valontan
  • Vomex

Phew! That’s quite a list. Whichever alias you know it by, they all work the same way — and the mechanism is pretty clever!

How Does Dramamine Work?

Dramamine helps our body maintain a sense of balance during those bumpy bus rides and turbulent takeovers. It works by blocking certain signals in the brain that trigger these uncomfortable symptoms, providing much-needed relief during travel. While taking a pill when symptoms kick in is an option (it’s never too late!), many travelers opt for taking the precaution of popping one an hour or so before even getting on the bus (or plane, or car).

As for dosage, the standard for adults is 50-100 mg every 4-6 hours, with 400 mg per day being the limit.

While Dramamine is all about reducing the unpleasant “side effects” of travel, it comes with a bit of baggage of its own. The common side effects are usually pretty mild:

  • Dry mouth. This is the most common side effect of Dramamine. While this isn’t great for mouth health (and can lead to cavities over time), there are solutions to this. A few sugar-free xylitol lozenges can balance things out by promoting salivation, nipping this problem in the bud.
  • Blurry vision. Dry eyes and blurry vision are also common side effects, so it’s a good idea to bring some eye drops along for the ride — especially for those of us who wear contacts.
  • Dizziness. We might feel dizzy, especially if we stand up too quickly after sitting or lying down. Since motion sickness also can make us dizzy, it’s extra important to be careful, especially if we have any medical conditions that might put us at greater risk of falling.
  • Nausea. Wait, what? Yes, ironically, Dramamine can cause nausea in some folks (obviously the opposite of what we’re going for, but it does happen!).

When Dramamine and Alcohol Cross Paths

So what happens when we add alcohol to the mix? There are a couple of reasons why the two are not great “travel companions”:

1. Boosted Sedative Effect


Dramamine can make us drowsy on its own, but with alcohol in the picture, the effect gets much more pronounced — sometimes to a dangerous degree. As a depressant, alcohol numbs our senses and slows cognitive processing while impairing our motor skills.

The reason has to do with the way it affects our brain chemistry. Alcohol tends to increase the activity of GABA, an inhibitory neurotransmitter that slows down the nervous system, while simultaneously toning down the effects of glutamate, its “excitatory” counterpart. The result? Our reflexes take a hit, our cognitive abilities are dulled, and we feel drowsy.

The booze-dramamine combo can dangerously enhance impairment, raising the risk of accidents and injuries, especially in activities requiring alertness, such as driving. However, even if we’re not behind the wheel, the extra grogginess can get in the way. (After all, nobody wants to miss their connecting flight!) And if we end up having several drinks, we could get into dangerous waters by slowing down our central nervous system so much that it becomes a health risk.

2. Dehydration


Alcohol is notorious for leaving us parched and depleted of electrolytes, and adding Dramamine to the mix can make things worse. This dehydrating duo will leave you twice as thirsty — especially after a long plane ride!

3. Intensification of Side Effects


Mixing alcohol and Dramamine can also worsen other side effects, such as dry mouth, blurred vision, and dizziness. If we’re already feeling drowsy, this could really spell trouble, especially for those of us who are a bit older.

Timing Alcohol and Dramamine 


You might be wondering, “How long after taking Dramamine can I drink alcohol?” The effects of the medication can last from 4 to 6 hours, and it takes about 1 to 3 hours for its peak effects to show up. Given its half-life, it's best to wait at least 24 hours after taking Dramamine before drinking so your body can fully process the medication. Waiting an extra few hours might reduce the risk of adverse interactions even more.

Is one drink okay to have with Dramamine? Not really. Even one drink can significantly increase the side effects and amp up the risks, so it's best to skip booze entirely until the medication has cleared from your system.

Dramamine for Hangovers


Given that nausea is a common hangover symptom, it seems that it would make sense to reach for a Dramamine pill for relief.

But is it a good idea? Not so much.

It’s true that Dramamine can potentially alleviate some symptoms of a hangover, such as nausea and a sense of balance disruption. However, Dramamine’s sedative effects can add to the grogginess and cognitive fuzziness often experienced during a hangover.

Moreover, taking Dramamine to combat hangover symptoms can be risky if alcohol is still present in the system. The combination can lead to increased drowsiness, dehydration, and further impairment of judgment and motor skills.

A Note on Addiction Potential


Moreover, it’s also worth noting that while Dramamine tends to be safe for many people when it comes to potential misuse, for some it’s been known to be habit-forming (sometimes very much so — we’re talking large daily doses). If we have a history of substance misuse, it’s important to be careful and mindful about our Dramamine intake.

What About Bonine and Alcohol?


Finally, many of us might have noticed that Dramamine has a travel partner that usually shares the same shelf in the drug store — Bonine. Is this a better choice to take along for the ride if we know we might drink?

Bonine (meclizine) is also marketed as a motion sickness aid but one that claims to work all day — as opposed to Dramamine’s 4- to 6-hour window. Unfortunately for those who might have been hoping Bonine could work as a booze-friendly alternative to Dramamine, this isn’t the case. Bonine shares the same risk of central nervous system suppression — along with increased dehydration and intensified side effects.

To ensure safety, it’s best to avoid alcohol when taking any motion sickness medication.

Strategies for Safety 

Strategies for Safety


Ready for some tips on how to relieve nausea and hangovers more effectively (and maybe prevent them altogether)? Here we go!

  • Don’t mix Dramamine and alcohol. Try to stay away from booze if you know you’ll need to take Dramamine. The risk of experiencing adverse effects from either substance goes way up when you mix them, so it’s not worth it.
  • Consider other motion sickness aids. Anti-nausea bands that put pressure on a specific spot on your wrist can work surprisingly well for many people. Ginger chewing gum or lozenges can also help.
  • When it comes to hangovers, water is your best friend. While the thought of drinking water when you’re nauseous might be, well, hard to stomach — stay with us. Rehydration (and replenishing electrolytes) is key, so try to find a palatable way to do so. Adding electrolyte mixes such as Liquid IV can be helpful, since in addition to adding extra hydration power, they also tend to make plain water taste a bit better. Take small sips and listen to your body!
  • Rest and gentle movement can ease the symptoms as well. Most importantly, give yourself a break when you’re feeling nauseous, whether it’s from motion sickness or a hangover. It might feel like it will last forever, but rest assured — you’ll feel better eventually. If you’re up for it, gentle movement such as walking can help your body start getting back to normal. Try to get outside to get some fresh air if possible, and again — keep it simple and don’t overdo it.

Tips for the Road


If you’re finding that alcohol is taking up a bit too much air time in your life in general — whether or not Dramamine is part of the picture — here are some additional tips for the journey.

  • Scope out your habits. Start by evaluating your drinking patterns. When do you tend to drink the most? Is it social occasions? After work? When you’re traveling? Try to get an overall “lay of the land” — no judgment.
  • Track your intake. Consider tracking how much you drink for a while. You might be surprised at what this practice can reveal! Consider an app such as Reframe that can help you track your drinks (and provide helpful insights along the way!).
  • Check out sober events in your area. There’s so much fun to be had beyond booze, and these days the “sober-curious” movement is stronger than ever. Get curious and explore! If you’re starting your vacation with a Dramamine on the plane or car ride, consider spending your first day booze-free. This will also ensure you’ll have plenty of energy for day one of your days off!

Summing Up


Nausea is, unfortunately, a part of life, and it’s great that Dramamine is here to help. But the not-so-helpful interactions between this medication and alcohol don’t have to be part of your journey. Happy booze-free, hangover-free travels!

Nobody likes to feel nauseous. It’s that indescribable feeling — not quite “pain” but somehow just as bad. And often there seems to be no escape from it. Philosopher Jean-Paul Sartre dedicated a whole novel — Nausea — to the pervasive sensation. He writes, “The nausea has not left me and I don't believe it will leave me so soon; but I no longer have to bear it, it is no longer an illness or a passing fit: it is I.”

So if you tend to get nauseous — on planes, buses, that spinning teacup ride at Disney World — you probably have your travel kit stocked with over-the-counter nausea aids (if only they were around when Sartre’s protagonist was grappling with his affliction!).

But wait a second, is it okay to pop a Dramamine before knocking back a glass of wine on the plane or have a beer after you get off that bumpy bus ride? What are the dangers of mixing Dramamine and alcohol — can you drink on Dramamine at all? And what about using Dramamine for hangover-related nausea? Let’s find out more!

When Motion Makes Us Sick

a glass of alcohol next to cigarettes

Unfortunately, motion sickness is a part of life for many of us. It can show up during our daily commute to work, in the back seat of an Uber, and even on vacation trips. As scientist Natasha Tuznik tells UC Davis Health, “A study conducted in 2019 found that almost everyone has experienced or will experience motion sickness at some point in their lifetime.”

This “sickness” goes way back — in fact, the word comes from the Greek naus, meaning “ship.” These days, of course, there are many other modes of transportation that seem to conspire to ruin our transit experience.

In a study published in Ergonomics, as many as 28.4% of people surveyed reported feeling ill during a total of 110 hours of test drives that included 5 types of vehicles and 17 different drivers. Moreover, 12.8% reported experiencing nausea, while 1.7% brave participants admitted to “losing their lunch” during the experiment!

Riding in cars is part of modern life. Thankfully, so is modern science! Enter: Dramamine.

Dramamine: A Lifeline for Motion Sickness

Dramamine (Dimenhydrinate) is an antihistamine used to kick the most unpleasant symptoms of motion sickness (such as nausea, vomiting, and dizziness) right to the curb. In fact, it can even prevent them from starting in the first place!

Know Dramamine by another name? That’s quite possible. According to ScienceDirect, this trusty travel companion has many aliases:

  • Andramine (or andrumin)
  • Antemin
  • Chloranautine
  • Detensor
  • Diamarin
  • Dimenhydrinat
  • Dommanate
  • Dramaban
  • Dramarin
  • Dramyl
  • Epha (or epharetard)
  • Faston
  • Gravol
  • Nausicalm (or paranausine)
  • Travel gum (as well as travelin, travelmin, or trawell)
  • Valontan
  • Vomex

Phew! That’s quite a list. Whichever alias you know it by, they all work the same way — and the mechanism is pretty clever!

How Does Dramamine Work?

Dramamine helps our body maintain a sense of balance during those bumpy bus rides and turbulent takeovers. It works by blocking certain signals in the brain that trigger these uncomfortable symptoms, providing much-needed relief during travel. While taking a pill when symptoms kick in is an option (it’s never too late!), many travelers opt for taking the precaution of popping one an hour or so before even getting on the bus (or plane, or car).

As for dosage, the standard for adults is 50-100 mg every 4-6 hours, with 400 mg per day being the limit.

While Dramamine is all about reducing the unpleasant “side effects” of travel, it comes with a bit of baggage of its own. The common side effects are usually pretty mild:

  • Dry mouth. This is the most common side effect of Dramamine. While this isn’t great for mouth health (and can lead to cavities over time), there are solutions to this. A few sugar-free xylitol lozenges can balance things out by promoting salivation, nipping this problem in the bud.
  • Blurry vision. Dry eyes and blurry vision are also common side effects, so it’s a good idea to bring some eye drops along for the ride — especially for those of us who wear contacts.
  • Dizziness. We might feel dizzy, especially if we stand up too quickly after sitting or lying down. Since motion sickness also can make us dizzy, it’s extra important to be careful, especially if we have any medical conditions that might put us at greater risk of falling.
  • Nausea. Wait, what? Yes, ironically, Dramamine can cause nausea in some folks (obviously the opposite of what we’re going for, but it does happen!).

When Dramamine and Alcohol Cross Paths

So what happens when we add alcohol to the mix? There are a couple of reasons why the two are not great “travel companions”:

1. Boosted Sedative Effect


Dramamine can make us drowsy on its own, but with alcohol in the picture, the effect gets much more pronounced — sometimes to a dangerous degree. As a depressant, alcohol numbs our senses and slows cognitive processing while impairing our motor skills.

The reason has to do with the way it affects our brain chemistry. Alcohol tends to increase the activity of GABA, an inhibitory neurotransmitter that slows down the nervous system, while simultaneously toning down the effects of glutamate, its “excitatory” counterpart. The result? Our reflexes take a hit, our cognitive abilities are dulled, and we feel drowsy.

The booze-dramamine combo can dangerously enhance impairment, raising the risk of accidents and injuries, especially in activities requiring alertness, such as driving. However, even if we’re not behind the wheel, the extra grogginess can get in the way. (After all, nobody wants to miss their connecting flight!) And if we end up having several drinks, we could get into dangerous waters by slowing down our central nervous system so much that it becomes a health risk.

2. Dehydration


Alcohol is notorious for leaving us parched and depleted of electrolytes, and adding Dramamine to the mix can make things worse. This dehydrating duo will leave you twice as thirsty — especially after a long plane ride!

3. Intensification of Side Effects


Mixing alcohol and Dramamine can also worsen other side effects, such as dry mouth, blurred vision, and dizziness. If we’re already feeling drowsy, this could really spell trouble, especially for those of us who are a bit older.

Timing Alcohol and Dramamine 


You might be wondering, “How long after taking Dramamine can I drink alcohol?” The effects of the medication can last from 4 to 6 hours, and it takes about 1 to 3 hours for its peak effects to show up. Given its half-life, it's best to wait at least 24 hours after taking Dramamine before drinking so your body can fully process the medication. Waiting an extra few hours might reduce the risk of adverse interactions even more.

Is one drink okay to have with Dramamine? Not really. Even one drink can significantly increase the side effects and amp up the risks, so it's best to skip booze entirely until the medication has cleared from your system.

Dramamine for Hangovers


Given that nausea is a common hangover symptom, it seems that it would make sense to reach for a Dramamine pill for relief.

But is it a good idea? Not so much.

It’s true that Dramamine can potentially alleviate some symptoms of a hangover, such as nausea and a sense of balance disruption. However, Dramamine’s sedative effects can add to the grogginess and cognitive fuzziness often experienced during a hangover.

Moreover, taking Dramamine to combat hangover symptoms can be risky if alcohol is still present in the system. The combination can lead to increased drowsiness, dehydration, and further impairment of judgment and motor skills.

A Note on Addiction Potential


Moreover, it’s also worth noting that while Dramamine tends to be safe for many people when it comes to potential misuse, for some it’s been known to be habit-forming (sometimes very much so — we’re talking large daily doses). If we have a history of substance misuse, it’s important to be careful and mindful about our Dramamine intake.

What About Bonine and Alcohol?


Finally, many of us might have noticed that Dramamine has a travel partner that usually shares the same shelf in the drug store — Bonine. Is this a better choice to take along for the ride if we know we might drink?

Bonine (meclizine) is also marketed as a motion sickness aid but one that claims to work all day — as opposed to Dramamine’s 4- to 6-hour window. Unfortunately for those who might have been hoping Bonine could work as a booze-friendly alternative to Dramamine, this isn’t the case. Bonine shares the same risk of central nervous system suppression — along with increased dehydration and intensified side effects.

To ensure safety, it’s best to avoid alcohol when taking any motion sickness medication.

Strategies for Safety 

Strategies for Safety


Ready for some tips on how to relieve nausea and hangovers more effectively (and maybe prevent them altogether)? Here we go!

  • Don’t mix Dramamine and alcohol. Try to stay away from booze if you know you’ll need to take Dramamine. The risk of experiencing adverse effects from either substance goes way up when you mix them, so it’s not worth it.
  • Consider other motion sickness aids. Anti-nausea bands that put pressure on a specific spot on your wrist can work surprisingly well for many people. Ginger chewing gum or lozenges can also help.
  • When it comes to hangovers, water is your best friend. While the thought of drinking water when you’re nauseous might be, well, hard to stomach — stay with us. Rehydration (and replenishing electrolytes) is key, so try to find a palatable way to do so. Adding electrolyte mixes such as Liquid IV can be helpful, since in addition to adding extra hydration power, they also tend to make plain water taste a bit better. Take small sips and listen to your body!
  • Rest and gentle movement can ease the symptoms as well. Most importantly, give yourself a break when you’re feeling nauseous, whether it’s from motion sickness or a hangover. It might feel like it will last forever, but rest assured — you’ll feel better eventually. If you’re up for it, gentle movement such as walking can help your body start getting back to normal. Try to get outside to get some fresh air if possible, and again — keep it simple and don’t overdo it.

Tips for the Road


If you’re finding that alcohol is taking up a bit too much air time in your life in general — whether or not Dramamine is part of the picture — here are some additional tips for the journey.

  • Scope out your habits. Start by evaluating your drinking patterns. When do you tend to drink the most? Is it social occasions? After work? When you’re traveling? Try to get an overall “lay of the land” — no judgment.
  • Track your intake. Consider tracking how much you drink for a while. You might be surprised at what this practice can reveal! Consider an app such as Reframe that can help you track your drinks (and provide helpful insights along the way!).
  • Check out sober events in your area. There’s so much fun to be had beyond booze, and these days the “sober-curious” movement is stronger than ever. Get curious and explore! If you’re starting your vacation with a Dramamine on the plane or car ride, consider spending your first day booze-free. This will also ensure you’ll have plenty of energy for day one of your days off!

Summing Up


Nausea is, unfortunately, a part of life, and it’s great that Dramamine is here to help. But the not-so-helpful interactions between this medication and alcohol don’t have to be part of your journey. Happy booze-free, hangover-free travels!

Alcohol and Medications
2024-04-20 9:00
Alcohol and Medications
Can You Drink Alcohol With Cephalexin?
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What can you not take with cephalexin? Well, drinking might be off the table for a while. If your doctor prescribes you cephalexin, alcohol may not be the best idea.

17 min read

Live Well With Reframe

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

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Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

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The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!

Read Full Article  →

It’s tough when a urinary tract infection disrupts your routine. It seems like those ultra-uncomfortable, ice-pick-painful symptoms find you at the worst possible moments — moments when you’re stressed and stretched thin.

When you finally carve out an hour for urgent care, the doctor asks you a few quick questions. She collects a urine sample before calling in a prescription.

When you pick up the pills, you see an unfamiliar name on the label: cephalexin. How is this drug going to affect your plans? You find yourself thinking about the upcoming weekend. What about your second date at that pop-up bar? Can you drink alcohol with cephalexin?  

Cephalexin Uses, Side Effects, and Contraindications

a hand holding a bottle of pills and a glass of liquid

Cephalexin belongs to a class of medications known as cephalosporin antibiotics, which work by destroying bacteria in the body. It is available under the brand names Daxbia, Keflex, Biocef, and Keftab, among others. Let’s explore this drug’s purpose, primary side effects, and interactions with other substances.

What Is Cephalexin Prescribed For?

Doctors prescribe cephalexin for bacterial infections, including pneumonia, upper respiratory infections (URIs), and urinary tract infections (UTIs). It’s also used when bacteria take up residence in the skin, ears, genitals, and bones. We may have received a cephalexin prescription after contracting certain strains of staph (Staphylococcus aureus) or strep (Streptococcus pyogenes).

It comes in one of three forms: a tablet, a capsule, or a liquid suspension. We’ll need to take it as prescribed; usually, that’s once every six to 12 hours. We’ll want to continue taking this medication until we run out of it, even if our symptoms resolve within the first few days. Quitting earlier may place us at risk of a rebound infection.

Contrary to popular belief, antibiotics like cephalexin don’t work on viral illnesses like the common cold or the flu. Using these drugs unnecessarily can increase antibiotic resistance, which makes these medications less effective over time.

Side Effects of Cephalexin

Fortunately, most of us will probably tolerate cephalexin very well. The most common side effect is diarrhea, followed by headache, nausea, and unusual vaginal discharge. In some cases, we might feel fatigued, confused, or agitated. If you have any of these symptoms for more than two days (or if they are particularly severe), reach out to your care team.

In rare cases, some people experience flu-like symptoms, including chills, stomach pain, dizziness, and fever. If you experience an allergic or severe skin reaction — characterized by itching, a rash, blisters, peeling of the skin, difficulty breathing, bloody stools, hallucinations, or swollen lymph nodes — seek emergency medical attention.

It is worth noting that those of us with diabetes may get false positive tests for sugar in our urine while taking this drug. We should talk to our doctor about this if it occurs; ideally, they’ll let us know what to expect before we fill the script.

Contraindications: What Can You Not Take With Cephalexin?

Cephalexin won’t work for everyone. We should not take this drug if we have a penicillin allergy, which may make us more likely to experience adverse effects. We’ll also want to tell our healthcare provider about any medications, vitamins, and supplements we’re currently taking, as this drug tends to interact with metformin and probenecid.

  • Metformin. This drug is especially important to those of us with diabetes because it controls the level of sugar in our blood. Taking cephalexin while on this medication can increase the amount of metformin in our blood by decreasing the amount processed by our kidneys. Liquid cephalexin might also contain sugar. For these reasons (among others), we should always tell our doctor whether we are diabetic.
  • Probenecid. Used to treat chronic gout and gout-related arthritis, probenecid alters the amount of uric acid in our blood. Taking this drug alongside cephalexin dramatically increases our cephalexin exposure. In some patients, that’s ideal — in others, it’s a serious detriment. Let your doctor know if you’re taking metformin, probenecid, or any other prescription drug.

When asking, “What can you not take with cephalexin?”, we want to remember that this drug can seriously interact with supplements. We should avoid taking any zinc while on this medication. Zinc interferes with the absorption of cephalexin, reducing its concentration in the bloodstream and rendering it less effective. Pro tip: Check your multivitamin for zinc or bring it to your doctor’s appointment before starting cephalexin.

If this antibiotic interacts with popular prescription drugs and over-the-counter vitamins, will drinking alcohol affect its efficacy?

Can You Drink on Cephalexin?

Some cephalosporin antibiotics react strongly with alcohol. For example, mixing cefotetan or cefoperazone with a few after-work cocktails can result in gastrointestinal or cardiac distress. Symptoms include irregular heartbeat, blood pressure changes, severe nausea, and vomiting. However, this isn’t the case for all antibiotics. So, can you drink on cephalexin?

Technically, it’s safe to drink on cephalexin. We won’t experience the host of uncomfortable (or life-threatening) symptoms we might usually associate with antibiotics and alcohol. However, that doesn’t mean it’s a good idea to imbibe while taking this medication.

Potential Interactions Between Cephalexin and Alcohol

Cephalexin and alcohol interact in three key ways. If we drink on cephalexin, we may deal with worse side effects, a weakened immune system, and a longer recovery time. Here’s how it works:

  • Alcohol may intensify cephalexin’s side effects. Drinking while on cephalexin can worsen the discomfort associated with this drug. Side effects like indigestion, nausea, and other gastrointestinal issues may be heightened when we add alcohol to the equation.
  • Drinking suppresses our immune system. Any time we drink, we channel our inner Meryl Streep from The Devil Wears Prada. We dump our coat and bag on our liver’s desk and tell it to drop whatever it’s doing to process that glass of wine. As we can imagine, that’s bad for our health — especially when our liver is doing its best to work through antibiotics, toxins, and all the other stuff that comes with being sick.
  • Alcohol may prolong our illness. Drinking can aggravate the issues that inspired us to seek medical attention in the first place, especially if we’re suffering from UTIs. The continued consumption of alcohol with cephalexin can create a cycle of symptoms.

So while it’s not necessarily dangerous to mix cephalexin and alcohol, it is certainly not beneficial.

How Long After Taking Cephalexin Can You Drink Alcohol?

If we want to avoid the interactions outlined above, we’ll probably want to abstain. Most of us will be on this medication for a maximum of 10 days, which isn’t long in the grand scheme of things. Consider framing this time as a break from hangovers while you focus on getting well. Plan to wait at least eight hours after your last dose of cephalexin to drink again.

Alcohol and UTIs

While drinking doesn’t directly cause UTIs, heavy drinking creates a perfect environment where these nasty infections can thrive.

Alcohol is a diuretic, which means it increases our urinary frequency. The more we use the bathroom, the more likely we are to become dehydrated, especially if we’re under the influence. The resulting dehydration can worsen our UTI symptoms, weaken our immune system, and make it more difficult for our body to overcome an existing infection, even if we’re already taking medication. Sound familiar?

Furthermore, alcohol is pretty acidic. This makes it especially irritating for the delicate tissue lining the inside of our bladder (which is already going through a lot!). Even when we’re healthy, heavy alcohol exposure and its associated inflammation can lead to a form of bladder discomfort known as cystitis. Unfortunately, the symptoms of alcohol-induced cystitis and UTIs are almost indistinguishable, making future diagnosis difficult.

All this is to say: if we’re taking cephalexin for a UTI or any other infection, we may want to rethink those drinks.

Alcohol-Free Options While on a Cephalexin Regimen

We can still enjoy ourselves while bouncing back from bacterial infections. Below are a few boozeless beverages for those of us avoiding alcohol on cephalexin.

  • Water, water, everywhere. This is always our #1 recommendation, especially while taking antibiotics. But it doesn’t have to be boring! Sure, you could break out the Brita, but consider treating yourself to sparkling water, aguas frescas, or other restorative favorites.

  • Herbal tea, anyone? Caffeine-free herbal teas like chamomile and peppermint can be especially soothing when we’re ill. Widely available variants like lemon ginger, lavender stress relief, and honey chai offer us the opportunity to combine mindfulness with hydration. If you’ve got a UTI, opt for green tea, which may have antimicrobial benefits.

  • Fruit juice (diluted, please!). Whether you’re a fan of fresh-squeezed OJ or just need to work through that carton of cranberry juice in the refrigerator door, juices can be a vitamin-rich alcohol alternative. Watering them down lowers their calorie content and sugar concentration, making them balanced options during an illness. Note: Steer clear of grapefruit juice, which can make antibiotics less effective.

  • Try non-alcoholic beer, wine, or liquor. If you’re missing the real thing, try the virgin version. Alcohol-free alternatives have gained serious momentum since the COVID-19 pandemic. You can grab these at your local grocery store or special order them online.

  • Cheers to healthy mocktails. Make your favorite craft cocktail, minus the booze, whenever you want to feel fancy on cephalexin. Need a little inspiration? Consider these refreshing recipes from the Reframe team.

We hope these spirit-free sips bring you joy in the days ahead. Remember to check with a healthcare professional before altering your diet, especially if you’ve been prescribed a new medication.

In-App Inspiration 

If you’re struggling to take a break from drinking, you’re not alone. It can be difficult to stay substance-free for the days or weeks it takes to battle an infection. If you need help staying on track, consider seeking support from Reframe during your course of cephalexin.

Reframe is a habit-cessation app powered by neuroscience. Our team includes recovery experts, academics, psychologists, and more. The proof is in our data — we’ve helped millions of people change their drinking habits for the better. To learn more, visit the App Store or Google Play today.

It’s tough when a urinary tract infection disrupts your routine. It seems like those ultra-uncomfortable, ice-pick-painful symptoms find you at the worst possible moments — moments when you’re stressed and stretched thin.

When you finally carve out an hour for urgent care, the doctor asks you a few quick questions. She collects a urine sample before calling in a prescription.

When you pick up the pills, you see an unfamiliar name on the label: cephalexin. How is this drug going to affect your plans? You find yourself thinking about the upcoming weekend. What about your second date at that pop-up bar? Can you drink alcohol with cephalexin?  

Cephalexin Uses, Side Effects, and Contraindications

a hand holding a bottle of pills and a glass of liquid

Cephalexin belongs to a class of medications known as cephalosporin antibiotics, which work by destroying bacteria in the body. It is available under the brand names Daxbia, Keflex, Biocef, and Keftab, among others. Let’s explore this drug’s purpose, primary side effects, and interactions with other substances.

What Is Cephalexin Prescribed For?

Doctors prescribe cephalexin for bacterial infections, including pneumonia, upper respiratory infections (URIs), and urinary tract infections (UTIs). It’s also used when bacteria take up residence in the skin, ears, genitals, and bones. We may have received a cephalexin prescription after contracting certain strains of staph (Staphylococcus aureus) or strep (Streptococcus pyogenes).

It comes in one of three forms: a tablet, a capsule, or a liquid suspension. We’ll need to take it as prescribed; usually, that’s once every six to 12 hours. We’ll want to continue taking this medication until we run out of it, even if our symptoms resolve within the first few days. Quitting earlier may place us at risk of a rebound infection.

Contrary to popular belief, antibiotics like cephalexin don’t work on viral illnesses like the common cold or the flu. Using these drugs unnecessarily can increase antibiotic resistance, which makes these medications less effective over time.

Side Effects of Cephalexin

Fortunately, most of us will probably tolerate cephalexin very well. The most common side effect is diarrhea, followed by headache, nausea, and unusual vaginal discharge. In some cases, we might feel fatigued, confused, or agitated. If you have any of these symptoms for more than two days (or if they are particularly severe), reach out to your care team.

In rare cases, some people experience flu-like symptoms, including chills, stomach pain, dizziness, and fever. If you experience an allergic or severe skin reaction — characterized by itching, a rash, blisters, peeling of the skin, difficulty breathing, bloody stools, hallucinations, or swollen lymph nodes — seek emergency medical attention.

It is worth noting that those of us with diabetes may get false positive tests for sugar in our urine while taking this drug. We should talk to our doctor about this if it occurs; ideally, they’ll let us know what to expect before we fill the script.

Contraindications: What Can You Not Take With Cephalexin?

Cephalexin won’t work for everyone. We should not take this drug if we have a penicillin allergy, which may make us more likely to experience adverse effects. We’ll also want to tell our healthcare provider about any medications, vitamins, and supplements we’re currently taking, as this drug tends to interact with metformin and probenecid.

  • Metformin. This drug is especially important to those of us with diabetes because it controls the level of sugar in our blood. Taking cephalexin while on this medication can increase the amount of metformin in our blood by decreasing the amount processed by our kidneys. Liquid cephalexin might also contain sugar. For these reasons (among others), we should always tell our doctor whether we are diabetic.
  • Probenecid. Used to treat chronic gout and gout-related arthritis, probenecid alters the amount of uric acid in our blood. Taking this drug alongside cephalexin dramatically increases our cephalexin exposure. In some patients, that’s ideal — in others, it’s a serious detriment. Let your doctor know if you’re taking metformin, probenecid, or any other prescription drug.

When asking, “What can you not take with cephalexin?”, we want to remember that this drug can seriously interact with supplements. We should avoid taking any zinc while on this medication. Zinc interferes with the absorption of cephalexin, reducing its concentration in the bloodstream and rendering it less effective. Pro tip: Check your multivitamin for zinc or bring it to your doctor’s appointment before starting cephalexin.

If this antibiotic interacts with popular prescription drugs and over-the-counter vitamins, will drinking alcohol affect its efficacy?

Can You Drink on Cephalexin?

Some cephalosporin antibiotics react strongly with alcohol. For example, mixing cefotetan or cefoperazone with a few after-work cocktails can result in gastrointestinal or cardiac distress. Symptoms include irregular heartbeat, blood pressure changes, severe nausea, and vomiting. However, this isn’t the case for all antibiotics. So, can you drink on cephalexin?

Technically, it’s safe to drink on cephalexin. We won’t experience the host of uncomfortable (or life-threatening) symptoms we might usually associate with antibiotics and alcohol. However, that doesn’t mean it’s a good idea to imbibe while taking this medication.

Potential Interactions Between Cephalexin and Alcohol

Cephalexin and alcohol interact in three key ways. If we drink on cephalexin, we may deal with worse side effects, a weakened immune system, and a longer recovery time. Here’s how it works:

  • Alcohol may intensify cephalexin’s side effects. Drinking while on cephalexin can worsen the discomfort associated with this drug. Side effects like indigestion, nausea, and other gastrointestinal issues may be heightened when we add alcohol to the equation.
  • Drinking suppresses our immune system. Any time we drink, we channel our inner Meryl Streep from The Devil Wears Prada. We dump our coat and bag on our liver’s desk and tell it to drop whatever it’s doing to process that glass of wine. As we can imagine, that’s bad for our health — especially when our liver is doing its best to work through antibiotics, toxins, and all the other stuff that comes with being sick.
  • Alcohol may prolong our illness. Drinking can aggravate the issues that inspired us to seek medical attention in the first place, especially if we’re suffering from UTIs. The continued consumption of alcohol with cephalexin can create a cycle of symptoms.

So while it’s not necessarily dangerous to mix cephalexin and alcohol, it is certainly not beneficial.

How Long After Taking Cephalexin Can You Drink Alcohol?

If we want to avoid the interactions outlined above, we’ll probably want to abstain. Most of us will be on this medication for a maximum of 10 days, which isn’t long in the grand scheme of things. Consider framing this time as a break from hangovers while you focus on getting well. Plan to wait at least eight hours after your last dose of cephalexin to drink again.

Alcohol and UTIs

While drinking doesn’t directly cause UTIs, heavy drinking creates a perfect environment where these nasty infections can thrive.

Alcohol is a diuretic, which means it increases our urinary frequency. The more we use the bathroom, the more likely we are to become dehydrated, especially if we’re under the influence. The resulting dehydration can worsen our UTI symptoms, weaken our immune system, and make it more difficult for our body to overcome an existing infection, even if we’re already taking medication. Sound familiar?

Furthermore, alcohol is pretty acidic. This makes it especially irritating for the delicate tissue lining the inside of our bladder (which is already going through a lot!). Even when we’re healthy, heavy alcohol exposure and its associated inflammation can lead to a form of bladder discomfort known as cystitis. Unfortunately, the symptoms of alcohol-induced cystitis and UTIs are almost indistinguishable, making future diagnosis difficult.

All this is to say: if we’re taking cephalexin for a UTI or any other infection, we may want to rethink those drinks.

Alcohol-Free Options While on a Cephalexin Regimen

We can still enjoy ourselves while bouncing back from bacterial infections. Below are a few boozeless beverages for those of us avoiding alcohol on cephalexin.

  • Water, water, everywhere. This is always our #1 recommendation, especially while taking antibiotics. But it doesn’t have to be boring! Sure, you could break out the Brita, but consider treating yourself to sparkling water, aguas frescas, or other restorative favorites.

  • Herbal tea, anyone? Caffeine-free herbal teas like chamomile and peppermint can be especially soothing when we’re ill. Widely available variants like lemon ginger, lavender stress relief, and honey chai offer us the opportunity to combine mindfulness with hydration. If you’ve got a UTI, opt for green tea, which may have antimicrobial benefits.

  • Fruit juice (diluted, please!). Whether you’re a fan of fresh-squeezed OJ or just need to work through that carton of cranberry juice in the refrigerator door, juices can be a vitamin-rich alcohol alternative. Watering them down lowers their calorie content and sugar concentration, making them balanced options during an illness. Note: Steer clear of grapefruit juice, which can make antibiotics less effective.

  • Try non-alcoholic beer, wine, or liquor. If you’re missing the real thing, try the virgin version. Alcohol-free alternatives have gained serious momentum since the COVID-19 pandemic. You can grab these at your local grocery store or special order them online.

  • Cheers to healthy mocktails. Make your favorite craft cocktail, minus the booze, whenever you want to feel fancy on cephalexin. Need a little inspiration? Consider these refreshing recipes from the Reframe team.

We hope these spirit-free sips bring you joy in the days ahead. Remember to check with a healthcare professional before altering your diet, especially if you’ve been prescribed a new medication.

In-App Inspiration 

If you’re struggling to take a break from drinking, you’re not alone. It can be difficult to stay substance-free for the days or weeks it takes to battle an infection. If you need help staying on track, consider seeking support from Reframe during your course of cephalexin.

Reframe is a habit-cessation app powered by neuroscience. Our team includes recovery experts, academics, psychologists, and more. The proof is in our data — we’ve helped millions of people change their drinking habits for the better. To learn more, visit the App Store or Google Play today.

Alcohol and Medications