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Latest Articles
2024-04-22 9:00
Alcohol and Medications
The Risks of Mixing Dramamine and Alcohol
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Can you drink on Dramamine, or is it too risky? Read about the possible dangers of this combination in our latest blog.

19 min read

Ready To Set Out on Your Alcohol Journey? Reframe Can Help!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today! 

Read Full Article  →

Nobody likes to feel nauseous. It’s that indescribable feeling — not quite “pain” but somehow just as bad. And often there seems to be no escape from it. Philosopher Jean-Paul Sartre dedicated a whole novel — Nausea — to the pervasive sensation. He writes, “The nausea has not left me and I don't believe it will leave me so soon; but I no longer have to bear it, it is no longer an illness or a passing fit: it is I.”

So if you tend to get nauseous — on planes, buses, that spinning teacup ride at Disney World — you probably have your travel kit stocked with over-the-counter nausea aids (if only they were around when Sartre’s protagonist was grappling with his affliction!).

But wait a second, is it okay to pop a Dramamine before knocking back a glass of wine on the plane or have a beer after you get off that bumpy bus ride? What are the dangers of mixing Dramamine and alcohol — can you drink on Dramamine at all? And what about using Dramamine for hangover-related nausea? Let’s find out more!

When Motion Makes Us Sick

a glass of alcohol next to cigarettes

Unfortunately, motion sickness is a part of life for many of us. It can show up during our daily commute to work, in the back seat of an Uber, and even on vacation trips. As scientist Natasha Tuznik tells UC Davis Health, “A study conducted in 2019 found that almost everyone has experienced or will experience motion sickness at some point in their lifetime.”

This “sickness” goes way back — in fact, the word comes from the Greek naus, meaning “ship.” These days, of course, there are many other modes of transportation that seem to conspire to ruin our transit experience.

In a study published in Ergonomics, as many as 28.4% of people surveyed reported feeling ill during a total of 110 hours of test drives that included 5 types of vehicles and 17 different drivers. Moreover, 12.8% reported experiencing nausea, while 1.7% brave participants admitted to “losing their lunch” during the experiment!

Riding in cars is part of modern life. Thankfully, so is modern science! Enter: Dramamine.

Dramamine: A Lifeline for Motion Sickness

Dramamine (Dimenhydrinate) is an antihistamine used to kick the most unpleasant symptoms of motion sickness (such as nausea, vomiting, and dizziness) right to the curb. In fact, it can even prevent them from starting in the first place!

Know Dramamine by another name? That’s quite possible. According to ScienceDirect, this trusty travel companion has many aliases:

  • Andramine (or andrumin)
  • Antemin
  • Chloranautine
  • Detensor
  • Diamarin
  • Dimenhydrinat
  • Dommanate
  • Dramaban
  • Dramarin
  • Dramyl
  • Epha (or epharetard)
  • Faston
  • Gravol
  • Nausicalm (or paranausine)
  • Travel gum (as well as travelin, travelmin, or trawell)
  • Valontan
  • Vomex

Phew! That’s quite a list. Whichever alias you know it by, they all work the same way — and the mechanism is pretty clever!

How Does Dramamine Work?

Dramamine helps our body maintain a sense of balance during those bumpy bus rides and turbulent takeovers. It works by blocking certain signals in the brain that trigger these uncomfortable symptoms, providing much-needed relief during travel. While taking a pill when symptoms kick in is an option (it’s never too late!), many travelers opt for taking the precaution of popping one an hour or so before even getting on the bus (or plane, or car).

As for dosage, the standard for adults is 50-100 mg every 4-6 hours, with 400 mg per day being the limit.

While Dramamine is all about reducing the unpleasant “side effects” of travel, it comes with a bit of baggage of its own. The common side effects are usually pretty mild:

  • Dry mouth. This is the most common side effect of Dramamine. While this isn’t great for mouth health (and can lead to cavities over time), there are solutions to this. A few sugar-free xylitol lozenges can balance things out by promoting salivation, nipping this problem in the bud.
  • Blurry vision. Dry eyes and blurry vision are also common side effects, so it’s a good idea to bring some eye drops along for the ride — especially for those of us who wear contacts.
  • Dizziness. We might feel dizzy, especially if we stand up too quickly after sitting or lying down. Since motion sickness also can make us dizzy, it’s extra important to be careful, especially if we have any medical conditions that might put us at greater risk of falling.
  • Nausea. Wait, what? Yes, ironically, Dramamine can cause nausea in some folks (obviously the opposite of what we’re going for, but it does happen!).

When Dramamine and Alcohol Cross Paths

So what happens when we add alcohol to the mix? There are a couple of reasons why the two are not great “travel companions”:

1. Boosted Sedative Effect


Dramamine can make us drowsy on its own, but with alcohol in the picture, the effect gets much more pronounced — sometimes to a dangerous degree. As a depressant, alcohol numbs our senses and slows cognitive processing while impairing our motor skills.

The reason has to do with the way it affects our brain chemistry. Alcohol tends to increase the activity of GABA, an inhibitory neurotransmitter that slows down the nervous system, while simultaneously toning down the effects of glutamate, its “excitatory” counterpart. The result? Our reflexes take a hit, our cognitive abilities are dulled, and we feel drowsy.

The booze-dramamine combo can dangerously enhance impairment, raising the risk of accidents and injuries, especially in activities requiring alertness, such as driving. However, even if we’re not behind the wheel, the extra grogginess can get in the way. (After all, nobody wants to miss their connecting flight!) And if we end up having several drinks, we could get into dangerous waters by slowing down our central nervous system so much that it becomes a health risk.

2. Dehydration


Alcohol is notorious for leaving us parched and depleted of electrolytes, and adding Dramamine to the mix can make things worse. This dehydrating duo will leave you twice as thirsty — especially after a long plane ride!

3. Intensification of Side Effects


Mixing alcohol and Dramamine can also worsen other side effects, such as dry mouth, blurred vision, and dizziness. If we’re already feeling drowsy, this could really spell trouble, especially for those of us who are a bit older.

Timing Alcohol and Dramamine 


You might be wondering, “How long after taking Dramamine can I drink alcohol?” The effects of the medication can last from 4 to 6 hours, and it takes about 1 to 3 hours for its peak effects to show up. Given its half-life, it's best to wait at least 24 hours after taking Dramamine before drinking so your body can fully process the medication. Waiting an extra few hours might reduce the risk of adverse interactions even more.

Is one drink okay to have with Dramamine? Not really. Even one drink can significantly increase the side effects and amp up the risks, so it's best to skip booze entirely until the medication has cleared from your system.

Dramamine for Hangovers


Given that nausea is a common hangover symptom, it seems that it would make sense to reach for a Dramamine pill for relief.

But is it a good idea? Not so much.

It’s true that Dramamine can potentially alleviate some symptoms of a hangover, such as nausea and a sense of balance disruption. However, Dramamine’s sedative effects can add to the grogginess and cognitive fuzziness often experienced during a hangover.

Moreover, taking Dramamine to combat hangover symptoms can be risky if alcohol is still present in the system. The combination can lead to increased drowsiness, dehydration, and further impairment of judgment and motor skills.

A Note on Addiction Potential


Moreover, it’s also worth noting that while Dramamine tends to be safe for many people when it comes to potential misuse, for some it’s been known to be habit-forming (sometimes very much so — we’re talking large daily doses). If we have a history of substance misuse, it’s important to be careful and mindful about our Dramamine intake.

What About Bonine and Alcohol?


Finally, many of us might have noticed that Dramamine has a travel partner that usually shares the same shelf in the drug store — Bonine. Is this a better choice to take along for the ride if we know we might drink?

Bonine (meclizine) is also marketed as a motion sickness aid but one that claims to work all day — as opposed to Dramamine’s 4- to 6-hour window. Unfortunately for those who might have been hoping Bonine could work as a booze-friendly alternative to Dramamine, this isn’t the case. Bonine shares the same risk of central nervous system suppression — along with increased dehydration and intensified side effects.

To ensure safety, it’s best to avoid alcohol when taking any motion sickness medication.

Strategies for Safety 

Strategies for Safety


Ready for some tips on how to relieve nausea and hangovers more effectively (and maybe prevent them altogether)? Here we go!

  • Don’t mix Dramamine and alcohol. Try to stay away from booze if you know you’ll need to take Dramamine. The risk of experiencing adverse effects from either substance goes way up when you mix them, so it’s not worth it.
  • Consider other motion sickness aids. Anti-nausea bands that put pressure on a specific spot on your wrist can work surprisingly well for many people. Ginger chewing gum or lozenges can also help.
  • When it comes to hangovers, water is your best friend. While the thought of drinking water when you’re nauseous might be, well, hard to stomach — stay with us. Rehydration (and replenishing electrolytes) is key, so try to find a palatable way to do so. Adding electrolyte mixes such as Liquid IV can be helpful, since in addition to adding extra hydration power, they also tend to make plain water taste a bit better. Take small sips and listen to your body!
  • Rest and gentle movement can ease the symptoms as well. Most importantly, give yourself a break when you’re feeling nauseous, whether it’s from motion sickness or a hangover. It might feel like it will last forever, but rest assured — you’ll feel better eventually. If you’re up for it, gentle movement such as walking can help your body start getting back to normal. Try to get outside to get some fresh air if possible, and again — keep it simple and don’t overdo it.

Tips for the Road


If you’re finding that alcohol is taking up a bit too much air time in your life in general — whether or not Dramamine is part of the picture — here are some additional tips for the journey.

  • Scope out your habits. Start by evaluating your drinking patterns. When do you tend to drink the most? Is it social occasions? After work? When you’re traveling? Try to get an overall “lay of the land” — no judgment.
  • Track your intake. Consider tracking how much you drink for a while. You might be surprised at what this practice can reveal! Consider an app such as Reframe that can help you track your drinks (and provide helpful insights along the way!).
  • Check out sober events in your area. There’s so much fun to be had beyond booze, and these days the “sober-curious” movement is stronger than ever. Get curious and explore! If you’re starting your vacation with a Dramamine on the plane or car ride, consider spending your first day booze-free. This will also ensure you’ll have plenty of energy for day one of your days off!

Summing Up


Nausea is, unfortunately, a part of life, and it’s great that Dramamine is here to help. But the not-so-helpful interactions between this medication and alcohol don’t have to be part of your journey. Happy booze-free, hangover-free travels!

Nobody likes to feel nauseous. It’s that indescribable feeling — not quite “pain” but somehow just as bad. And often there seems to be no escape from it. Philosopher Jean-Paul Sartre dedicated a whole novel — Nausea — to the pervasive sensation. He writes, “The nausea has not left me and I don't believe it will leave me so soon; but I no longer have to bear it, it is no longer an illness or a passing fit: it is I.”

So if you tend to get nauseous — on planes, buses, that spinning teacup ride at Disney World — you probably have your travel kit stocked with over-the-counter nausea aids (if only they were around when Sartre’s protagonist was grappling with his affliction!).

But wait a second, is it okay to pop a Dramamine before knocking back a glass of wine on the plane or have a beer after you get off that bumpy bus ride? What are the dangers of mixing Dramamine and alcohol — can you drink on Dramamine at all? And what about using Dramamine for hangover-related nausea? Let’s find out more!

When Motion Makes Us Sick

a glass of alcohol next to cigarettes

Unfortunately, motion sickness is a part of life for many of us. It can show up during our daily commute to work, in the back seat of an Uber, and even on vacation trips. As scientist Natasha Tuznik tells UC Davis Health, “A study conducted in 2019 found that almost everyone has experienced or will experience motion sickness at some point in their lifetime.”

This “sickness” goes way back — in fact, the word comes from the Greek naus, meaning “ship.” These days, of course, there are many other modes of transportation that seem to conspire to ruin our transit experience.

In a study published in Ergonomics, as many as 28.4% of people surveyed reported feeling ill during a total of 110 hours of test drives that included 5 types of vehicles and 17 different drivers. Moreover, 12.8% reported experiencing nausea, while 1.7% brave participants admitted to “losing their lunch” during the experiment!

Riding in cars is part of modern life. Thankfully, so is modern science! Enter: Dramamine.

Dramamine: A Lifeline for Motion Sickness

Dramamine (Dimenhydrinate) is an antihistamine used to kick the most unpleasant symptoms of motion sickness (such as nausea, vomiting, and dizziness) right to the curb. In fact, it can even prevent them from starting in the first place!

Know Dramamine by another name? That’s quite possible. According to ScienceDirect, this trusty travel companion has many aliases:

  • Andramine (or andrumin)
  • Antemin
  • Chloranautine
  • Detensor
  • Diamarin
  • Dimenhydrinat
  • Dommanate
  • Dramaban
  • Dramarin
  • Dramyl
  • Epha (or epharetard)
  • Faston
  • Gravol
  • Nausicalm (or paranausine)
  • Travel gum (as well as travelin, travelmin, or trawell)
  • Valontan
  • Vomex

Phew! That’s quite a list. Whichever alias you know it by, they all work the same way — and the mechanism is pretty clever!

How Does Dramamine Work?

Dramamine helps our body maintain a sense of balance during those bumpy bus rides and turbulent takeovers. It works by blocking certain signals in the brain that trigger these uncomfortable symptoms, providing much-needed relief during travel. While taking a pill when symptoms kick in is an option (it’s never too late!), many travelers opt for taking the precaution of popping one an hour or so before even getting on the bus (or plane, or car).

As for dosage, the standard for adults is 50-100 mg every 4-6 hours, with 400 mg per day being the limit.

While Dramamine is all about reducing the unpleasant “side effects” of travel, it comes with a bit of baggage of its own. The common side effects are usually pretty mild:

  • Dry mouth. This is the most common side effect of Dramamine. While this isn’t great for mouth health (and can lead to cavities over time), there are solutions to this. A few sugar-free xylitol lozenges can balance things out by promoting salivation, nipping this problem in the bud.
  • Blurry vision. Dry eyes and blurry vision are also common side effects, so it’s a good idea to bring some eye drops along for the ride — especially for those of us who wear contacts.
  • Dizziness. We might feel dizzy, especially if we stand up too quickly after sitting or lying down. Since motion sickness also can make us dizzy, it’s extra important to be careful, especially if we have any medical conditions that might put us at greater risk of falling.
  • Nausea. Wait, what? Yes, ironically, Dramamine can cause nausea in some folks (obviously the opposite of what we’re going for, but it does happen!).

When Dramamine and Alcohol Cross Paths

So what happens when we add alcohol to the mix? There are a couple of reasons why the two are not great “travel companions”:

1. Boosted Sedative Effect


Dramamine can make us drowsy on its own, but with alcohol in the picture, the effect gets much more pronounced — sometimes to a dangerous degree. As a depressant, alcohol numbs our senses and slows cognitive processing while impairing our motor skills.

The reason has to do with the way it affects our brain chemistry. Alcohol tends to increase the activity of GABA, an inhibitory neurotransmitter that slows down the nervous system, while simultaneously toning down the effects of glutamate, its “excitatory” counterpart. The result? Our reflexes take a hit, our cognitive abilities are dulled, and we feel drowsy.

The booze-dramamine combo can dangerously enhance impairment, raising the risk of accidents and injuries, especially in activities requiring alertness, such as driving. However, even if we’re not behind the wheel, the extra grogginess can get in the way. (After all, nobody wants to miss their connecting flight!) And if we end up having several drinks, we could get into dangerous waters by slowing down our central nervous system so much that it becomes a health risk.

2. Dehydration


Alcohol is notorious for leaving us parched and depleted of electrolytes, and adding Dramamine to the mix can make things worse. This dehydrating duo will leave you twice as thirsty — especially after a long plane ride!

3. Intensification of Side Effects


Mixing alcohol and Dramamine can also worsen other side effects, such as dry mouth, blurred vision, and dizziness. If we’re already feeling drowsy, this could really spell trouble, especially for those of us who are a bit older.

Timing Alcohol and Dramamine 


You might be wondering, “How long after taking Dramamine can I drink alcohol?” The effects of the medication can last from 4 to 6 hours, and it takes about 1 to 3 hours for its peak effects to show up. Given its half-life, it's best to wait at least 24 hours after taking Dramamine before drinking so your body can fully process the medication. Waiting an extra few hours might reduce the risk of adverse interactions even more.

Is one drink okay to have with Dramamine? Not really. Even one drink can significantly increase the side effects and amp up the risks, so it's best to skip booze entirely until the medication has cleared from your system.

Dramamine for Hangovers


Given that nausea is a common hangover symptom, it seems that it would make sense to reach for a Dramamine pill for relief.

But is it a good idea? Not so much.

It’s true that Dramamine can potentially alleviate some symptoms of a hangover, such as nausea and a sense of balance disruption. However, Dramamine’s sedative effects can add to the grogginess and cognitive fuzziness often experienced during a hangover.

Moreover, taking Dramamine to combat hangover symptoms can be risky if alcohol is still present in the system. The combination can lead to increased drowsiness, dehydration, and further impairment of judgment and motor skills.

A Note on Addiction Potential


Moreover, it’s also worth noting that while Dramamine tends to be safe for many people when it comes to potential misuse, for some it’s been known to be habit-forming (sometimes very much so — we’re talking large daily doses). If we have a history of substance misuse, it’s important to be careful and mindful about our Dramamine intake.

What About Bonine and Alcohol?


Finally, many of us might have noticed that Dramamine has a travel partner that usually shares the same shelf in the drug store — Bonine. Is this a better choice to take along for the ride if we know we might drink?

Bonine (meclizine) is also marketed as a motion sickness aid but one that claims to work all day — as opposed to Dramamine’s 4- to 6-hour window. Unfortunately for those who might have been hoping Bonine could work as a booze-friendly alternative to Dramamine, this isn’t the case. Bonine shares the same risk of central nervous system suppression — along with increased dehydration and intensified side effects.

To ensure safety, it’s best to avoid alcohol when taking any motion sickness medication.

Strategies for Safety 

Strategies for Safety


Ready for some tips on how to relieve nausea and hangovers more effectively (and maybe prevent them altogether)? Here we go!

  • Don’t mix Dramamine and alcohol. Try to stay away from booze if you know you’ll need to take Dramamine. The risk of experiencing adverse effects from either substance goes way up when you mix them, so it’s not worth it.
  • Consider other motion sickness aids. Anti-nausea bands that put pressure on a specific spot on your wrist can work surprisingly well for many people. Ginger chewing gum or lozenges can also help.
  • When it comes to hangovers, water is your best friend. While the thought of drinking water when you’re nauseous might be, well, hard to stomach — stay with us. Rehydration (and replenishing electrolytes) is key, so try to find a palatable way to do so. Adding electrolyte mixes such as Liquid IV can be helpful, since in addition to adding extra hydration power, they also tend to make plain water taste a bit better. Take small sips and listen to your body!
  • Rest and gentle movement can ease the symptoms as well. Most importantly, give yourself a break when you’re feeling nauseous, whether it’s from motion sickness or a hangover. It might feel like it will last forever, but rest assured — you’ll feel better eventually. If you’re up for it, gentle movement such as walking can help your body start getting back to normal. Try to get outside to get some fresh air if possible, and again — keep it simple and don’t overdo it.

Tips for the Road


If you’re finding that alcohol is taking up a bit too much air time in your life in general — whether or not Dramamine is part of the picture — here are some additional tips for the journey.

  • Scope out your habits. Start by evaluating your drinking patterns. When do you tend to drink the most? Is it social occasions? After work? When you’re traveling? Try to get an overall “lay of the land” — no judgment.
  • Track your intake. Consider tracking how much you drink for a while. You might be surprised at what this practice can reveal! Consider an app such as Reframe that can help you track your drinks (and provide helpful insights along the way!).
  • Check out sober events in your area. There’s so much fun to be had beyond booze, and these days the “sober-curious” movement is stronger than ever. Get curious and explore! If you’re starting your vacation with a Dramamine on the plane or car ride, consider spending your first day booze-free. This will also ensure you’ll have plenty of energy for day one of your days off!

Summing Up


Nausea is, unfortunately, a part of life, and it’s great that Dramamine is here to help. But the not-so-helpful interactions between this medication and alcohol don’t have to be part of your journey. Happy booze-free, hangover-free travels!

Alcohol and Medications
Popular
2024-11-08 9:00
Alcohol and Medications
Can You Drink Alcohol on Mounjaro?
This is some text inside of a div block.

Alcohol and Mounjaro don’t interact directly but mixing the two is still risky. Check out our latest blog for more info on why drinking on Mounjaro isn’t recommended.

14 min read

Prioritize Your Health With Guidance From Reframe!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet hundreds of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!

Read Full Article  →

Finding information on whether it’s okay to drink alcohol while on Mounjaro can be a bit like climbing Mt. Kilimanjaro — it’s not easy. While not exactly like climbing a 19,000 ft. mountain, the ambiguous guidance on mixing alcohol and Mounjaro can make our decision on whether to drink or not a bit more muddled than it needs to be.  

While the label may state no direct interactions between alcohol and Mounjaro, alcohol’s indirect effects on the medication can open the floodgates to a host of different complications. Let’s get to the bottom of how Mounjaro and alcohol interact to understand why drinking on Mounjaro may not be a good idea. 

Mounjaro: Management for Type 2 Diabetes

A person grips a small electronic gadget alongside a bottle of water

Mounjaro, the brand name for tirzepatide, is a relatively new treatment for type 2 diabetes approved by the Federal Drug Administration (FDA). It is a weekly injection that is used to help manage blood sugar levels and lower the risk of common complications that are associated with diabetes. Mounjaro dosages range from 2.5-15 mg/0.5 mL with the starting dosage typically at 2.5 and increasing as needed. 

The drug is categorized as a dual-agonist that stimulates two different hormones  — glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. GIP receptors promote the production of insulin and increase insulin sensitivity. GLP-1 receptors also stimulate the production of insulin and reduce elevated blood glucose. By increasing the production of GIP and GLP-1, Mounjaro helps treat type 2 diabetes by regulating blood sugar and decreasing the risk of diabetes-related complications. 

Like other diabetes treatments, Mounjaro has also been studied and tested for its effectiveness in weight loss. How does a type 2 diabetes treatment aid in weight loss?

Understanding Mounjaro for Weight Loss

While Mounjaro and other popular medications such as Ozempic and Trulicity originated as diabetes treatments, they’ve also more recently been looked at as a weight loss treatment for clinical obesity due to their mechanisms. 

GLP-1 receptor agonists like Ozempic and Trulicity help with weight loss by regulating blood sugar and delaying gastric emptying. Research shows that Mounjaro, which has a dual GLP-1/GIP mechanism, promises even greater effectiveness. GIP stimulates satiety in our hypothalamus which signals to our brain that we are full. It also enhances the function of GLP-1, and together they increase insulin production, decrease appetite, and improve insulin sensitivity — all contributing to weight loss.

Mounjaro was recently FDA-approved as a weight loss treatment for those who are obese, overweight, and also have weight-related medical conditions. The weight loss treatment is produced by Eli Lilly under the new name Zepbound. The dosages for Zepbound mirror Mounjaro, starting at 2.5 mg and increasing after 4 weeks if needed. As the first weight loss drug of its kind with its dual mechanism, interest has skyrocketed — creating a shortage. This prompted the company to release a statement strongly discouraging off-label use of the drug. If we do happen to be prescribed Mounjaro for type 2 diabetes or Zepbound for weight loss, we may be looking to get the best use out of it (as it’s hard to get our hands on it). Could alcohol affect the medication? 

Interactions Between Mounjaro and Alcohol

Drug interactions refer to changes in the mechanism of a drug due to factors such as foods, drinks, or other drugs. Since alcohol is a drug, it interacts with many prescription and over-the-counter medications. 

Mounjaro and alcohol don’t have any direct interactions. However, this doesn’t mean that alcohol won’t negatively affect Mounjaro. It only confirms that the mechanism of Mounjaro on our body will continue to work in the same way even when alcohol is introduced into our system. That being said, is it a good idea to drink?

Can You Drink Alcohol on Mounjaro?

Drinking on Mounjaro is not recommended. Although there aren’t any direct interactions between Mounjaro and alcohol, drinking can still cause adverse effects and increase the risk of complications. 

Alcohol has significant effects on many systems in our body, which disrupt key factors that Mounjaro targets. These may include factors such as blood sugar, appetite, insulin, and more. Drinking isn’t recommended while taking Mounjaro, but what about Zepbound (Mounjaro used for weight loss)?

Negative Effects of Mixing Alcohol and Mounjaro

Mixing alcohol and Mounjaro may not cause immediate dangers to our health like other direct drug interactions. However, it opens the door to adverse effects and increased complications that include the following:

  • Hypoglycemia. Hypoglycemia refers to low blood sugar, which is a potential side effect of Mounjaro. Alcohol can also cause hypoglycemia, especially for those of us with diabetes. Drinking while taking Mounjaro heightens the risk of this side effect — leading to potentially dangerous symptoms including confusion, loss of coordination, loss of consciousness, and seizures.
  • Decreased effectiveness. Alcohol negatively affects the same markers that Mounjaro targets, including blood sugar, insulin, and satiety. By disrupting these markers, the effectiveness of the medication may be decreased. 
  • Exacerbated side effects. Mounjaro and alcohol have many overlapping side effects including nausea, vomiting, hypoglycemia, and more. Drinking while taking Mounjaro can heighten these negative side effects. 
  • Long-term health conditions. Both Mounjaro and alcohol are associated with kidney damage and pancreatitis. Mixing the two can amplify the risk of developing these long-term health issues.
  • Interaction with other treatments. Type 2 diabetes and obesity are linked with co-occurring conditions. Drinking while taking Mounjaro can present the risk of having interactions with other medications and exacerbate co-occurring conditions.

Alcohol is a complex drug that can cause negative impacts, even without direct interactions. Let’s explore some ways we can approach alcohol more mindfully and safely while on Mounjaro.

Tips for Navigating Mounjaro and Alcohol Consumption

Drinking while taking Mounjaro isn’t recommended, but if we do choose to consume alcohol, safe drinking practices can help limit the potential consequences. Six practices we can implement to navigate drinking while taking Mounjaro more safely include the following:

1. Consult a Doctor 

Alcohol can affect us differently due to individual differences. Consulting with a physician provides us with more detailed guidance focused on our individual needs.

2. Know Limits 

A “safe” amount of alcohol when taking Mounjaro isn’t able to be determined, but understanding our individual limits helps us avoid excessive alcohol consumption that can negatively affect our weight, blood sugar, or overall health. 

3. Quit/Cut Back

Quitting or cutting back on alcohol removes or limits the negative effects that it may cause. This can improve different aspects of our life including our health, mental health, and social well-being. 

4. Manage Blood Sugar 

Keeping track and managing our blood sugar helps us avoid potential adverse effects. Since hypoglycemia is a common side effect of Mounjaro and drinking alcohol, it's even more crucial to monitor our blood sugar levels to ensure our safety.

5. Healthy Lifestyle

Following a healthy lifestyle through eating balanced meals and staying active supports the mechanisms of Mounjaro and helps to improve our overall well-being. It sets us up for the best chance to recover from the toxins in alcohol and fight against the conditions that Mounjaro aims to treat. 

6. Seek Support

Managing health conditions and/or working through an unhealthy relationship with alcohol isn’t easy. Different types of social support can help us overcome challenges and remind us that we aren’t alone.

These mindful actions can reduce the indirect interactions between alcohol and Mounjaro, but the safest bet is to remove the risk entirely by replacing alcohol with alcohol-free alternatives.

Main Takeaways

Mounjaro is a newer medication used to treat type 2 diabetes and/or obesity. The first drug of its kind with its unique dual mechanism, Mounjaro is difficult to get a hold of. Understanding the risks associated with drinking on Mounjaro including worsened side effects, decreased effectiveness, and long-term health conditions helps us get the most out of the medication and keep us safe. Quitting or cutting back while on Mounjaro promotes a healthier tomorrow! 

Finding information on whether it’s okay to drink alcohol while on Mounjaro can be a bit like climbing Mt. Kilimanjaro — it’s not easy. While not exactly like climbing a 19,000 ft. mountain, the ambiguous guidance on mixing alcohol and Mounjaro can make our decision on whether to drink or not a bit more muddled than it needs to be.  

While the label may state no direct interactions between alcohol and Mounjaro, alcohol’s indirect effects on the medication can open the floodgates to a host of different complications. Let’s get to the bottom of how Mounjaro and alcohol interact to understand why drinking on Mounjaro may not be a good idea. 

Mounjaro: Management for Type 2 Diabetes

A person grips a small electronic gadget alongside a bottle of water

Mounjaro, the brand name for tirzepatide, is a relatively new treatment for type 2 diabetes approved by the Federal Drug Administration (FDA). It is a weekly injection that is used to help manage blood sugar levels and lower the risk of common complications that are associated with diabetes. Mounjaro dosages range from 2.5-15 mg/0.5 mL with the starting dosage typically at 2.5 and increasing as needed. 

The drug is categorized as a dual-agonist that stimulates two different hormones  — glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. GIP receptors promote the production of insulin and increase insulin sensitivity. GLP-1 receptors also stimulate the production of insulin and reduce elevated blood glucose. By increasing the production of GIP and GLP-1, Mounjaro helps treat type 2 diabetes by regulating blood sugar and decreasing the risk of diabetes-related complications. 

Like other diabetes treatments, Mounjaro has also been studied and tested for its effectiveness in weight loss. How does a type 2 diabetes treatment aid in weight loss?

Understanding Mounjaro for Weight Loss

While Mounjaro and other popular medications such as Ozempic and Trulicity originated as diabetes treatments, they’ve also more recently been looked at as a weight loss treatment for clinical obesity due to their mechanisms. 

GLP-1 receptor agonists like Ozempic and Trulicity help with weight loss by regulating blood sugar and delaying gastric emptying. Research shows that Mounjaro, which has a dual GLP-1/GIP mechanism, promises even greater effectiveness. GIP stimulates satiety in our hypothalamus which signals to our brain that we are full. It also enhances the function of GLP-1, and together they increase insulin production, decrease appetite, and improve insulin sensitivity — all contributing to weight loss.

Mounjaro was recently FDA-approved as a weight loss treatment for those who are obese, overweight, and also have weight-related medical conditions. The weight loss treatment is produced by Eli Lilly under the new name Zepbound. The dosages for Zepbound mirror Mounjaro, starting at 2.5 mg and increasing after 4 weeks if needed. As the first weight loss drug of its kind with its dual mechanism, interest has skyrocketed — creating a shortage. This prompted the company to release a statement strongly discouraging off-label use of the drug. If we do happen to be prescribed Mounjaro for type 2 diabetes or Zepbound for weight loss, we may be looking to get the best use out of it (as it’s hard to get our hands on it). Could alcohol affect the medication? 

Interactions Between Mounjaro and Alcohol

Drug interactions refer to changes in the mechanism of a drug due to factors such as foods, drinks, or other drugs. Since alcohol is a drug, it interacts with many prescription and over-the-counter medications. 

Mounjaro and alcohol don’t have any direct interactions. However, this doesn’t mean that alcohol won’t negatively affect Mounjaro. It only confirms that the mechanism of Mounjaro on our body will continue to work in the same way even when alcohol is introduced into our system. That being said, is it a good idea to drink?

Can You Drink Alcohol on Mounjaro?

Drinking on Mounjaro is not recommended. Although there aren’t any direct interactions between Mounjaro and alcohol, drinking can still cause adverse effects and increase the risk of complications. 

Alcohol has significant effects on many systems in our body, which disrupt key factors that Mounjaro targets. These may include factors such as blood sugar, appetite, insulin, and more. Drinking isn’t recommended while taking Mounjaro, but what about Zepbound (Mounjaro used for weight loss)?

Negative Effects of Mixing Alcohol and Mounjaro

Mixing alcohol and Mounjaro may not cause immediate dangers to our health like other direct drug interactions. However, it opens the door to adverse effects and increased complications that include the following:

  • Hypoglycemia. Hypoglycemia refers to low blood sugar, which is a potential side effect of Mounjaro. Alcohol can also cause hypoglycemia, especially for those of us with diabetes. Drinking while taking Mounjaro heightens the risk of this side effect — leading to potentially dangerous symptoms including confusion, loss of coordination, loss of consciousness, and seizures.
  • Decreased effectiveness. Alcohol negatively affects the same markers that Mounjaro targets, including blood sugar, insulin, and satiety. By disrupting these markers, the effectiveness of the medication may be decreased. 
  • Exacerbated side effects. Mounjaro and alcohol have many overlapping side effects including nausea, vomiting, hypoglycemia, and more. Drinking while taking Mounjaro can heighten these negative side effects. 
  • Long-term health conditions. Both Mounjaro and alcohol are associated with kidney damage and pancreatitis. Mixing the two can amplify the risk of developing these long-term health issues.
  • Interaction with other treatments. Type 2 diabetes and obesity are linked with co-occurring conditions. Drinking while taking Mounjaro can present the risk of having interactions with other medications and exacerbate co-occurring conditions.

Alcohol is a complex drug that can cause negative impacts, even without direct interactions. Let’s explore some ways we can approach alcohol more mindfully and safely while on Mounjaro.

Tips for Navigating Mounjaro and Alcohol Consumption

Drinking while taking Mounjaro isn’t recommended, but if we do choose to consume alcohol, safe drinking practices can help limit the potential consequences. Six practices we can implement to navigate drinking while taking Mounjaro more safely include the following:

1. Consult a Doctor 

Alcohol can affect us differently due to individual differences. Consulting with a physician provides us with more detailed guidance focused on our individual needs.

2. Know Limits 

A “safe” amount of alcohol when taking Mounjaro isn’t able to be determined, but understanding our individual limits helps us avoid excessive alcohol consumption that can negatively affect our weight, blood sugar, or overall health. 

3. Quit/Cut Back

Quitting or cutting back on alcohol removes or limits the negative effects that it may cause. This can improve different aspects of our life including our health, mental health, and social well-being. 

4. Manage Blood Sugar 

Keeping track and managing our blood sugar helps us avoid potential adverse effects. Since hypoglycemia is a common side effect of Mounjaro and drinking alcohol, it's even more crucial to monitor our blood sugar levels to ensure our safety.

5. Healthy Lifestyle

Following a healthy lifestyle through eating balanced meals and staying active supports the mechanisms of Mounjaro and helps to improve our overall well-being. It sets us up for the best chance to recover from the toxins in alcohol and fight against the conditions that Mounjaro aims to treat. 

6. Seek Support

Managing health conditions and/or working through an unhealthy relationship with alcohol isn’t easy. Different types of social support can help us overcome challenges and remind us that we aren’t alone.

These mindful actions can reduce the indirect interactions between alcohol and Mounjaro, but the safest bet is to remove the risk entirely by replacing alcohol with alcohol-free alternatives.

Main Takeaways

Mounjaro is a newer medication used to treat type 2 diabetes and/or obesity. The first drug of its kind with its unique dual mechanism, Mounjaro is difficult to get a hold of. Understanding the risks associated with drinking on Mounjaro including worsened side effects, decreased effectiveness, and long-term health conditions helps us get the most out of the medication and keep us safe. Quitting or cutting back while on Mounjaro promotes a healthier tomorrow! 

Alcohol and Medications
2024-11-08 9:00
Alcohol and Medications
Can You Drink on Cyclobenzaprine?
This is some text inside of a div block.

Is mixing cyclobenzaprine and alcohol a bad idea? Find out why Flexeril and alcohol are not a great mix and learn how to stay safe and keep your muscles healthy.

18 min read

Heal Your Muscles (and More) by Quitting or Cutting Back on Alcohol With Reframe

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet hundreds of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!

Read Full Article  →

If you’ve ever gotten a painful muscle spasm, you know it’s no joke. It can jolt you out of sleep or strike during the day, as you go about your business and are suddenly stopped in your tracks by what feels like a pair of tyrannosaurus jaws chomping into your muscles. Those moments can fill you with panic as you try to remember the tricks you’ve heard from your grandmother or read about online. Fill a bathtub with hot water and soak your foot in it? Stand on your heel and bend your toes back? Ugh! Nothing seems to help.

When our muscle pain and spasms become a regular thing, we might end up taking medication such as a muscle relaxant. Cyclobenzaprine (known by the brand name Flexeril) is often prescribed to alleviate spasms related to all sorts of musculoskeletal conditions. But what about cyclobenzaprine and alcohol — is it okay to mix the two? Can you drink on muscle relaxers in general, and what are the possible dangers? Let’s find out!

What Is Cyclobenzaprine?

An individual is grasping a bottle of pills

According to NIH, cyclobenzaprine, a muscle relaxant, is prescribed to help relieve pain from muscle spasms caused by different musculoskeletal conditions. It’s usually not a stand-alone measure, and is used in combination with rest, physical therapy exercises, and other techniques that help relax muscles, quiet pain, and relieve discomfort caused by strains, sprains, and various types of muscle injuries.

What Are Muscle Relaxants?

Muscle relaxants might sound very modern, but they’re actually nothing new! The earliest “muscle relaxants” were actually poison-tipped arrows used as weapons by peoples in the Amazon Basin in South America. The European explorers picked up on their potential medical applications and used them in early experiments that eventually led to the development of cyclobenzaprine and its many pharmacological cousins. And don’t worry — the variety doled out by the local pharmacy won’t do us any harm, provided we take them as prescribed.

How Do Muscle Relaxants Work?

Muscle relaxants work through a few different pathways that all have the same goal — quieting down those overactive signals to prevent painful spasms and muscle hyperactivity. Let’s see what their main mechanisms are and where cyclobenzaprine fits in.

  • Antispastics. Antispastics work on the spinal cord or skeletal muscles directly to stop involuntary spasms and excessive tightness “on site.” They are often used to treat conditions such as multiple sclerosis or spinal cord injuries and include medications like baclofen and dantrolene.
  • Antispasmodics. Antispasmodics work a bit more remotely. While some target muscle fibers directly, others reduce the intensity of the signals transmitted by the nerves to alleviate pain. 

    This is where cyclobenzaprine comes in! According to NCBI, cyclobenzaprine quiets down the central nervous system (CNS) and is structurally similar to tricyclic antidepressants. The result? Effective short-term relief of muscle spasms.
  • Opioids. While opioids don’t affect the muscles directly, they do have a muscle-relaxing effect and can be used for pain relief. Instead of controlling muscle spasms, they tweak the perception of pain in our brain, which can sometimes play an indirect (but important) role in muscle tension and spasms. Opioids bind to pain receptors in the brain, inhibiting the transmission of pain signals and creating an overall relaxing effect. A word of caution: they’re addictive, so tread carefully!)

The full list of options for muscle ailments is much longer, but these are the highlights. There are many individual factors that come into play when choosing the right option, and our physician can give us the best idea of which course of treatment is right for us.

Why Cyclobenzaprine and Alcohol Don’t Mix

Can you drink on muscle relaxers? And more specifically, can you drink alcohol with cyclobenzaprine? As it turns out, it’s not a good idea for several reasons. 

Both of the main muscle relaxer types (antispastics and antispasmodics) can have negative interactions with alcohol. Most of the dangers center on amplified side effects (especially sedation). For a deeper look at the dangers of mixing alcohol and muscle relaxants in general, check out “Muscle Relaxers and Alcohol: A Dangerous Mix.” For now, let’s take a closer look at cyclobenzaprine and alcohol in particular.

Dry, Dizzy, and Drowsy

One of the main reasons it’s best to avoid the combo has to do with some gnarly side effects we can end up with as a result. According to NIH, cyclobenzaprine comes with some fairly typical ones, as well as potentially dangerous ones. None of them mix too well with booze.

  • Dry mouth. Alcohol is notoriously dehydrating, so that parched mouth feeling might get worse.
  • Gastrointestinal side effects. Cyclobenzaprine can bring on nausea and heartburn. Alcohol can add to both (while throwing a few extras, such as stomach pain and diarrhea, into the mix). Needless to say, none of this will add up to a fun night.
  • Sedative side effects. Cyclobenzaprine can cause dizziness and extreme tiredness. According to Drugs.com, mixing cyclobenzaprine and alcohol can drastically increase some of the sedating side effects, amping up dizziness, drowsiness, and concentration difficulties. Some of us might even find it leads to thinking and judgment impairments (more so than booze alone). 

This last set of effects is the main reason mixing the two is not recommended, since it increases the chances of having a dangerous fall or another accident. Besides, the sedation could land us in dangerous waters if our heart and breathing rate slows down too much, causing respiratory depression. 

Because of this, driving or operating machinery is out of the question (even if we’re below the legal alcohol limit). It’s important to stay safe and protect others around us!

Liver Trouble 

Another reason why cyclobenzaprine and alcohol are a dangerous combination? Our liver probably won’t be too happy with the mix. Both substances are processed by the liver, which is already in danger of becoming overwhelmed by alcohol alone. Adding another burdensome to-do list item to its task list is asking for trouble. 

Studies show that mixing alcohol and medications that are processed by the liver leads to a less-than-favorable metabolic fallout. Specifically, we end up with elevated levels of certain enzymes. The result? Higher fat deposits and overall stress that can eventually result in liver disease and other complications.

Heart Concerns

Alcohol’s effect on the heart could also put us at risk if we’re taking cyclobenzaprine. Booze is notorious for messing with our blood pressure, decreasing it at first through vasodilation (the widening of blood vessels) before leading to a rebound effect. It also causes potentially dangerous arrhythmias and increases our heart rate. Over time, these disruptions could even lead to cardiomyopathy — a serious form of heart disease. (For more information take a look at “How Does Alcohol Affect the Heart?”).

Muscle Matters

Moreover, alcohol’s effect on muscles can be counterproductive during the healing process. Science shows that alcohol contributes to muscle degeneration, gets in the way of muscle-building, and even leads to muscle atrophy in the long run.

Alcohol and Cyclobenzaprine: Addiction Potential

Finally, there’s the matter of dependency. As we know, alcohol can be notoriously addictive since it affects the brain’s levels of dopamine, a “reward” neurotransmitter involved in pleasure-seeking behavior. Dopamine gets released through activities that make us feel good (delicious food, good company, a date that ends well — you get the picture). However, substances like alcohol cause an unnatural flood of dopamine that the brain eventually gets used to and comes to expect, leading us to become more and more dependent on that weekly (or nightly) drink.

Muscle relaxers affect our cognition a bit differently but can play a role in this process. By affecting our nervous system, they lower our “cognitive defenses,” making it more likely we’ll jump into certain situations or make decisions without thinking. Our inhibitions might be lower, and we might end up drinking more as a result, paving the way for potential problems in the future.

Why Cyclobenzaprine and Alcohol Don’t Mix

How Long After Taking Cyclobenzaprine Can I Drink Alcohol?

Cyclobenzaprine has a half-life of about 18 hours, which means that within 18 hours, half of it is no longer in our body. (It’s usually taken 3 times a day and is meant for short-term use — 2 or 3 weeks at most). Doctors generally recommend waiting at least 48 hours before drinking. (Of course, we might want to take a longer break from booze once we see the benefits!)

Tips To Stay Safe

How can we stay safe when it comes to alcohol and cyclobenzaprine? Here are a few tips to start with.

  1. Steer clear of the cyclobenzaprine-alcohol combo. To avoid potentially dangerous interactions (as well as putting too much stress on the liver or muscles), don’t mix cyclobenzaprine with alcohol.
  2. Give your muscles a chance to heal. Cutting back on booze in general will give your muscles a much-needed chance to recover. Plus, cutting back can lead to a myriad other “bonus” benefits, such as better sleep, a healthier immune system, and weight loss.
  3. Get plenty of rest. Speaking of sleep, make sure to get enough rest. Sleep is when most healing happens, so give your body a chance to tap into its own healing powers by getting some high-quality slumber in a sleep-friendly environment (dark, cool, without distractions or interruptions).
  4. Nourish your muscles. To nourish your muscles, make sure to get plenty of protein from healthy sources, such as fish, lean meats, eggs, dairy, and tofu. Proteins serve as the building blocks of muscles, and variety is key! Moreover, adding antioxidants to reduce inflammation can speed up the recovery process. (Think berries, nuts, green leafy vegetables, and turmeric.)
  5. Keep moving. Follow your doctor’s advice if you have an injury, but once you have the green light, engage in light activity whenever possible. If the gym isn’t your thing, don’t sweat it! (Pardon the pun.) Mindful movement — anything from gentle yoga to a slow stroll around the neighborhood park — will do the trick.
  6. See a physical therapist. Sometimes adding a specific exercise routine targeted to your particular muscle problem can work wonders in speeding up recovery. They’re often covered by insurance, so check out one in your area to see what they recommend!

With these tips, you can stay safe when it comes to cyclobenzaprine and alcohol while helping your muscles heal. We wish you a speedy recovery!

Nourish Your Muscle Memory

For some extra motivation, keep in mind that it’s not just your muscles that will reap the rewards — going easy on the booze and taking care of your physical health will also bring you closer to being the healthiest and happiest version of yourself.

We can think of our habits themselves as a sort of “mental muscle” we can exercise, leading us to form healthy habits over time. As Monjyoti Bhattacharyya writes in A Relentless Pursuit of the Truth: A Philosophical Guide to Living a Life of Fulfillment and Meaning, “We become muscular at whatever we are repeatedly exposed to. Same is true for all the unconscious habits we develop.” Let’s take care of our muscles — both the physical kind and the metaphorical muscles of habit that help us transform our lives and become the best versions of ourselves.

If you’ve ever gotten a painful muscle spasm, you know it’s no joke. It can jolt you out of sleep or strike during the day, as you go about your business and are suddenly stopped in your tracks by what feels like a pair of tyrannosaurus jaws chomping into your muscles. Those moments can fill you with panic as you try to remember the tricks you’ve heard from your grandmother or read about online. Fill a bathtub with hot water and soak your foot in it? Stand on your heel and bend your toes back? Ugh! Nothing seems to help.

When our muscle pain and spasms become a regular thing, we might end up taking medication such as a muscle relaxant. Cyclobenzaprine (known by the brand name Flexeril) is often prescribed to alleviate spasms related to all sorts of musculoskeletal conditions. But what about cyclobenzaprine and alcohol — is it okay to mix the two? Can you drink on muscle relaxers in general, and what are the possible dangers? Let’s find out!

What Is Cyclobenzaprine?

An individual is grasping a bottle of pills

According to NIH, cyclobenzaprine, a muscle relaxant, is prescribed to help relieve pain from muscle spasms caused by different musculoskeletal conditions. It’s usually not a stand-alone measure, and is used in combination with rest, physical therapy exercises, and other techniques that help relax muscles, quiet pain, and relieve discomfort caused by strains, sprains, and various types of muscle injuries.

What Are Muscle Relaxants?

Muscle relaxants might sound very modern, but they’re actually nothing new! The earliest “muscle relaxants” were actually poison-tipped arrows used as weapons by peoples in the Amazon Basin in South America. The European explorers picked up on their potential medical applications and used them in early experiments that eventually led to the development of cyclobenzaprine and its many pharmacological cousins. And don’t worry — the variety doled out by the local pharmacy won’t do us any harm, provided we take them as prescribed.

How Do Muscle Relaxants Work?

Muscle relaxants work through a few different pathways that all have the same goal — quieting down those overactive signals to prevent painful spasms and muscle hyperactivity. Let’s see what their main mechanisms are and where cyclobenzaprine fits in.

  • Antispastics. Antispastics work on the spinal cord or skeletal muscles directly to stop involuntary spasms and excessive tightness “on site.” They are often used to treat conditions such as multiple sclerosis or spinal cord injuries and include medications like baclofen and dantrolene.
  • Antispasmodics. Antispasmodics work a bit more remotely. While some target muscle fibers directly, others reduce the intensity of the signals transmitted by the nerves to alleviate pain. 

    This is where cyclobenzaprine comes in! According to NCBI, cyclobenzaprine quiets down the central nervous system (CNS) and is structurally similar to tricyclic antidepressants. The result? Effective short-term relief of muscle spasms.
  • Opioids. While opioids don’t affect the muscles directly, they do have a muscle-relaxing effect and can be used for pain relief. Instead of controlling muscle spasms, they tweak the perception of pain in our brain, which can sometimes play an indirect (but important) role in muscle tension and spasms. Opioids bind to pain receptors in the brain, inhibiting the transmission of pain signals and creating an overall relaxing effect. A word of caution: they’re addictive, so tread carefully!)

The full list of options for muscle ailments is much longer, but these are the highlights. There are many individual factors that come into play when choosing the right option, and our physician can give us the best idea of which course of treatment is right for us.

Why Cyclobenzaprine and Alcohol Don’t Mix

Can you drink on muscle relaxers? And more specifically, can you drink alcohol with cyclobenzaprine? As it turns out, it’s not a good idea for several reasons. 

Both of the main muscle relaxer types (antispastics and antispasmodics) can have negative interactions with alcohol. Most of the dangers center on amplified side effects (especially sedation). For a deeper look at the dangers of mixing alcohol and muscle relaxants in general, check out “Muscle Relaxers and Alcohol: A Dangerous Mix.” For now, let’s take a closer look at cyclobenzaprine and alcohol in particular.

Dry, Dizzy, and Drowsy

One of the main reasons it’s best to avoid the combo has to do with some gnarly side effects we can end up with as a result. According to NIH, cyclobenzaprine comes with some fairly typical ones, as well as potentially dangerous ones. None of them mix too well with booze.

  • Dry mouth. Alcohol is notoriously dehydrating, so that parched mouth feeling might get worse.
  • Gastrointestinal side effects. Cyclobenzaprine can bring on nausea and heartburn. Alcohol can add to both (while throwing a few extras, such as stomach pain and diarrhea, into the mix). Needless to say, none of this will add up to a fun night.
  • Sedative side effects. Cyclobenzaprine can cause dizziness and extreme tiredness. According to Drugs.com, mixing cyclobenzaprine and alcohol can drastically increase some of the sedating side effects, amping up dizziness, drowsiness, and concentration difficulties. Some of us might even find it leads to thinking and judgment impairments (more so than booze alone). 

This last set of effects is the main reason mixing the two is not recommended, since it increases the chances of having a dangerous fall or another accident. Besides, the sedation could land us in dangerous waters if our heart and breathing rate slows down too much, causing respiratory depression. 

Because of this, driving or operating machinery is out of the question (even if we’re below the legal alcohol limit). It’s important to stay safe and protect others around us!

Liver Trouble 

Another reason why cyclobenzaprine and alcohol are a dangerous combination? Our liver probably won’t be too happy with the mix. Both substances are processed by the liver, which is already in danger of becoming overwhelmed by alcohol alone. Adding another burdensome to-do list item to its task list is asking for trouble. 

Studies show that mixing alcohol and medications that are processed by the liver leads to a less-than-favorable metabolic fallout. Specifically, we end up with elevated levels of certain enzymes. The result? Higher fat deposits and overall stress that can eventually result in liver disease and other complications.

Heart Concerns

Alcohol’s effect on the heart could also put us at risk if we’re taking cyclobenzaprine. Booze is notorious for messing with our blood pressure, decreasing it at first through vasodilation (the widening of blood vessels) before leading to a rebound effect. It also causes potentially dangerous arrhythmias and increases our heart rate. Over time, these disruptions could even lead to cardiomyopathy — a serious form of heart disease. (For more information take a look at “How Does Alcohol Affect the Heart?”).

Muscle Matters

Moreover, alcohol’s effect on muscles can be counterproductive during the healing process. Science shows that alcohol contributes to muscle degeneration, gets in the way of muscle-building, and even leads to muscle atrophy in the long run.

Alcohol and Cyclobenzaprine: Addiction Potential

Finally, there’s the matter of dependency. As we know, alcohol can be notoriously addictive since it affects the brain’s levels of dopamine, a “reward” neurotransmitter involved in pleasure-seeking behavior. Dopamine gets released through activities that make us feel good (delicious food, good company, a date that ends well — you get the picture). However, substances like alcohol cause an unnatural flood of dopamine that the brain eventually gets used to and comes to expect, leading us to become more and more dependent on that weekly (or nightly) drink.

Muscle relaxers affect our cognition a bit differently but can play a role in this process. By affecting our nervous system, they lower our “cognitive defenses,” making it more likely we’ll jump into certain situations or make decisions without thinking. Our inhibitions might be lower, and we might end up drinking more as a result, paving the way for potential problems in the future.

Why Cyclobenzaprine and Alcohol Don’t Mix

How Long After Taking Cyclobenzaprine Can I Drink Alcohol?

Cyclobenzaprine has a half-life of about 18 hours, which means that within 18 hours, half of it is no longer in our body. (It’s usually taken 3 times a day and is meant for short-term use — 2 or 3 weeks at most). Doctors generally recommend waiting at least 48 hours before drinking. (Of course, we might want to take a longer break from booze once we see the benefits!)

Tips To Stay Safe

How can we stay safe when it comes to alcohol and cyclobenzaprine? Here are a few tips to start with.

  1. Steer clear of the cyclobenzaprine-alcohol combo. To avoid potentially dangerous interactions (as well as putting too much stress on the liver or muscles), don’t mix cyclobenzaprine with alcohol.
  2. Give your muscles a chance to heal. Cutting back on booze in general will give your muscles a much-needed chance to recover. Plus, cutting back can lead to a myriad other “bonus” benefits, such as better sleep, a healthier immune system, and weight loss.
  3. Get plenty of rest. Speaking of sleep, make sure to get enough rest. Sleep is when most healing happens, so give your body a chance to tap into its own healing powers by getting some high-quality slumber in a sleep-friendly environment (dark, cool, without distractions or interruptions).
  4. Nourish your muscles. To nourish your muscles, make sure to get plenty of protein from healthy sources, such as fish, lean meats, eggs, dairy, and tofu. Proteins serve as the building blocks of muscles, and variety is key! Moreover, adding antioxidants to reduce inflammation can speed up the recovery process. (Think berries, nuts, green leafy vegetables, and turmeric.)
  5. Keep moving. Follow your doctor’s advice if you have an injury, but once you have the green light, engage in light activity whenever possible. If the gym isn’t your thing, don’t sweat it! (Pardon the pun.) Mindful movement — anything from gentle yoga to a slow stroll around the neighborhood park — will do the trick.
  6. See a physical therapist. Sometimes adding a specific exercise routine targeted to your particular muscle problem can work wonders in speeding up recovery. They’re often covered by insurance, so check out one in your area to see what they recommend!

With these tips, you can stay safe when it comes to cyclobenzaprine and alcohol while helping your muscles heal. We wish you a speedy recovery!

Nourish Your Muscle Memory

For some extra motivation, keep in mind that it’s not just your muscles that will reap the rewards — going easy on the booze and taking care of your physical health will also bring you closer to being the healthiest and happiest version of yourself.

We can think of our habits themselves as a sort of “mental muscle” we can exercise, leading us to form healthy habits over time. As Monjyoti Bhattacharyya writes in A Relentless Pursuit of the Truth: A Philosophical Guide to Living a Life of Fulfillment and Meaning, “We become muscular at whatever we are repeatedly exposed to. Same is true for all the unconscious habits we develop.” Let’s take care of our muscles — both the physical kind and the metaphorical muscles of habit that help us transform our lives and become the best versions of ourselves.

Alcohol and Medications
2024-11-26 9:00
Alcohol and Medications
Cialis and Alcohol Interactions
This is some text inside of a div block.

Ever wondered if Cialis interacts with alcohol? Find out in our latest blog, where we uncover everything you need to know about mixing these two popular date-night companions. The answers might surprise you!

15 min read

Drink Less, Stay Safe, and Improve Sexual Health With Reframe!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet hundreds of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!

Read Full Article  →

It’s date night, you’ve had a couple of glasses of wine, and now the bedroom is calling your names. But wait. You got a new prescription for Cialis earlier this week. Is it safe to take it after drinking wine? Should you take your chances or hold off? 

Hopefully, you’re reading this before you find yourself frantically pacing and Googling answers in the bathroom. Fortunately, you’re not the only one who has ever asked this question, and we have answers. In this blog, we’ll cover all you need to know about the interactions between Cialis and alcohol.

Cialis: An Overview

A glass of whiskey beside scattered pills on a rustic wooden table

Cialis is a brand name of the phosphodiesterase-5 inhibitor (PDE5) known as tadalafil. Much like its cousin, Viagra (sildenafil), it’s mainly used to treat erectile dysfunction (ED). It works by boosting the chemicals the body naturally produces during arousal. The main difference is that Cialis stays in the body longer (up to 36 hours) than Viagra.

The general guideline is to take Cialis at least 30 minutes before sexual activity, but not more than once daily. It’s generally proven safe and effective, but it may come with unwanted, mood-killing side effects like headache, indigestion, back pain, muscle pain, flushing, or even a stuffy nose. If it’s any encouragement, the muscle aches usually come 12-24 hours after taking it.

The most important side effect to be aware of is the tendency for Cialis to lower your blood pressure, which is particularly important where alcohol is involved.

Alcohol’s Effects on the Body

We’ve all seen what happens when someone throws back a few too many drinks. Word vomit, actual vomit, and impromptu table dances are some of the most common consequences (according to Hollywood, anyway). Drunk driving accidents are among the more tragic consequences. How do a few drinks lead to such chaos? 

When ethanol, the main intoxicating ingredient in alcohol, enters the bloodstream, it affects nearly every vital system and organ. At first, we get the familiar “buzz” that helps us let loose and relax, but if we keep drinking beyond that, chaos ensues. It fogs our central nervous system, leading to impaired coordination and judgment. It overwhelms our liver, affecting metabolism and long-term liver health. It disrupts our hormones, our heart, and our immune system. And most people don’t realize it, but it also wreaks havoc on our reproductive system, which we’ll get into later.

Taking Cialis with Alcohol

So what happens when you take Cialis before or after drinking alcohol? How do tadalafil and alcohol interact?

As a general rule, keep in mind that ethanol can affect any drug. It can affect metabolism and absorption, increase side effects, and more. When it comes to tadalafil specifically, there are a couple of interactions to be aware of: 

  • Delayed metabolism. Our liver is responsible for breaking down substances such as alcohol and medications. The liver will always prioritize breaking down alcohol over other substances. What does that mean for us if we’re taking Cialis? In a nutshell, it means it will stay in our system longer, which could decrease its efficacy and increase the duration of its effects (and side effects).

  • Increased vasodilation. Alcohol and tadalafil are both vasodilators, meaning they both lower blood pressure. If we combine the two, our blood pressure could drop to dangerous levels, causing headaches, dizziness, and fainting (plus any related injuries). Given the general purpose of Cialis, you can imagine how that could change your plans for the evening. 

While neither of these interactions is necessarily life-threatening, it’s important to be aware of and plan for them to avoid further complications. Now, let’s get to the burning question. 

Safe Night Out Essential Tips for a Secure Evening

Can You Drink Alcohol With Cialis?

If you have a clean bill of health, and Cialis is the only drug you’re taking, sipping on a glass of wine at dinner likely won’t cause any problems. Throwing back whiskey shots on an empty stomach, however, could be a different story with or without Cialis in the picture. Here are some general guidelines to help you plan a safe night out or in.

Safe Zone (1-2 drinks)

If you have a drink or two before or after taking Cialis, it probably won’t cause any problems. There is no known interaction (like pain pills and alcohol) that would make the mixture inherently dangerous.

Decreased Effectiveness (3-4 drinks)

If you drink more than two, it might decrease the effectiveness of Cialis and/or increase the likelihood of its side effects. Either way, it could definitely put a damper on date night.

Danger Zone (5 or more drinks)

If you drink five or more drinks within two hours, (classified as binge drinking), it could lead to several serious health problems and poor decisions (and possibly fewer date nights in the future). When combined with Cialis, the main concern with binge drinking is a sudden drop in blood pressure, known as orthostatic hypotension

When it comes to alcohol, less is always safer, especially when other medications are involved. 

Alcohol and Sexual Health

If mixing Cialis and alcohol is a concern for you, it might be worth exploring how alcohol affects our sexual health. Research shows that persistent alcohol use is directly linked to sexual dysfunction, ranging from decreased libido to physical difficulties. If that’s the case, could quitting alcohol help resolve the need for Cialis? Let’s find out.

There are many different causes of ED, from illness to medications to emotional issues. Whatever the reason, alcohol can make matters worse.


  • Alcohol is a depressant. Alcohol slows down the central nervous system, which slows down the chemical messengers that travel from the brain to other parts of the body. This is why our speech slurs and our feet stumble. Likewise, alcohol can make it difficult for a man to get or maintain an erection.

  • Alcohol affects testosterone levels. While small amounts of alcohol can increase testosterone (and libido), studies show that heavy or chronic alcohol use can decrease testosterone, leading to sexual dysfunction.

  • Alcohol affects fertility. Sexual dysfunction alone can interfere with fertility, but heavy alcohol use also diminishes sperm quality, making it more difficult to conceive. This can be good news for some, but it can be devastating news for those who are trying to conceive. 

  • Alcohol affects relationships. While “hookup culture” might make it appear that alcohol boosts your sex life, real relationships affected by alcohol misuse tell us otherwise. Studies have shown that heavy alcohol use decreases relationship satisfaction and increases marital distress, neither of which is conducive to a healthy sex life. 

To sum up, while we can’t say that quitting or even cutting back on alcohol will cure ED, we can confidently say it will help. 

Safely Improve Sexual Health

Fortunately, there are things you can do to stay safe while your mind adjusts to a new way of thinking. 


  • Take Cialis as prescribed. Nothing less, nothing more. For every guideline and warning on a prescription label, there’s a study or incident to back it up. Don’t find out the hard way why they are there.
  • Plan carefully. When you’re planning a date that involves drinking, plan out the timing of your drinks (and meals) so there’s not much in your system when it’s time to take Cialis. 
  • Know the signs of low blood pressure. If you’re drinking while taking Cialis, pay attention to your body’s signals. If you get a headache or start feeling dizzy, stop drinking and find a place to sit down as soon as possible to avoid falling.
  • Eat and sleep well. A healthy diet and sleep pattern can both affect hormone levels, stress levels, and other factors that can contribute to ED. Better overall health will lead to better sexual health. 
  • Limit alcohol intake. If alcohol has become a third wheel (or worse — the main character) on all your dates, it might be time to reconsider or “reframe” your relationship with it. Reframe is here to guide you every step of the way with neuroscience-backed programs to help you reach your goals. 


Above all, be sure to repair and/or nourish your relationships, whether they be sexual or not. Stronger relationships lead to greater satisfaction and well-being in all areas of your life. 

Alcohol and Cialis in Sum

While mixing alcohol and Cialis isn’t inherently life-threatening, it could lead to dangerous blood pressure fluctuations. Furthermore, alcohol could counteract the effects of Cialis. If you’re looking to improve your sexual health, nourish your body with good sleep and nutrition, and nurture the relationships that mean the most to you. And as always, pay close attention to new symptoms and seek medical advice when needed. We’re here to help and cheer you on!

It’s date night, you’ve had a couple of glasses of wine, and now the bedroom is calling your names. But wait. You got a new prescription for Cialis earlier this week. Is it safe to take it after drinking wine? Should you take your chances or hold off? 

Hopefully, you’re reading this before you find yourself frantically pacing and Googling answers in the bathroom. Fortunately, you’re not the only one who has ever asked this question, and we have answers. In this blog, we’ll cover all you need to know about the interactions between Cialis and alcohol.

Cialis: An Overview

A glass of whiskey beside scattered pills on a rustic wooden table

Cialis is a brand name of the phosphodiesterase-5 inhibitor (PDE5) known as tadalafil. Much like its cousin, Viagra (sildenafil), it’s mainly used to treat erectile dysfunction (ED). It works by boosting the chemicals the body naturally produces during arousal. The main difference is that Cialis stays in the body longer (up to 36 hours) than Viagra.

The general guideline is to take Cialis at least 30 minutes before sexual activity, but not more than once daily. It’s generally proven safe and effective, but it may come with unwanted, mood-killing side effects like headache, indigestion, back pain, muscle pain, flushing, or even a stuffy nose. If it’s any encouragement, the muscle aches usually come 12-24 hours after taking it.

The most important side effect to be aware of is the tendency for Cialis to lower your blood pressure, which is particularly important where alcohol is involved.

Alcohol’s Effects on the Body

We’ve all seen what happens when someone throws back a few too many drinks. Word vomit, actual vomit, and impromptu table dances are some of the most common consequences (according to Hollywood, anyway). Drunk driving accidents are among the more tragic consequences. How do a few drinks lead to such chaos? 

When ethanol, the main intoxicating ingredient in alcohol, enters the bloodstream, it affects nearly every vital system and organ. At first, we get the familiar “buzz” that helps us let loose and relax, but if we keep drinking beyond that, chaos ensues. It fogs our central nervous system, leading to impaired coordination and judgment. It overwhelms our liver, affecting metabolism and long-term liver health. It disrupts our hormones, our heart, and our immune system. And most people don’t realize it, but it also wreaks havoc on our reproductive system, which we’ll get into later.

Taking Cialis with Alcohol

So what happens when you take Cialis before or after drinking alcohol? How do tadalafil and alcohol interact?

As a general rule, keep in mind that ethanol can affect any drug. It can affect metabolism and absorption, increase side effects, and more. When it comes to tadalafil specifically, there are a couple of interactions to be aware of: 

  • Delayed metabolism. Our liver is responsible for breaking down substances such as alcohol and medications. The liver will always prioritize breaking down alcohol over other substances. What does that mean for us if we’re taking Cialis? In a nutshell, it means it will stay in our system longer, which could decrease its efficacy and increase the duration of its effects (and side effects).

  • Increased vasodilation. Alcohol and tadalafil are both vasodilators, meaning they both lower blood pressure. If we combine the two, our blood pressure could drop to dangerous levels, causing headaches, dizziness, and fainting (plus any related injuries). Given the general purpose of Cialis, you can imagine how that could change your plans for the evening. 

While neither of these interactions is necessarily life-threatening, it’s important to be aware of and plan for them to avoid further complications. Now, let’s get to the burning question. 

Safe Night Out Essential Tips for a Secure Evening

Can You Drink Alcohol With Cialis?

If you have a clean bill of health, and Cialis is the only drug you’re taking, sipping on a glass of wine at dinner likely won’t cause any problems. Throwing back whiskey shots on an empty stomach, however, could be a different story with or without Cialis in the picture. Here are some general guidelines to help you plan a safe night out or in.

Safe Zone (1-2 drinks)

If you have a drink or two before or after taking Cialis, it probably won’t cause any problems. There is no known interaction (like pain pills and alcohol) that would make the mixture inherently dangerous.

Decreased Effectiveness (3-4 drinks)

If you drink more than two, it might decrease the effectiveness of Cialis and/or increase the likelihood of its side effects. Either way, it could definitely put a damper on date night.

Danger Zone (5 or more drinks)

If you drink five or more drinks within two hours, (classified as binge drinking), it could lead to several serious health problems and poor decisions (and possibly fewer date nights in the future). When combined with Cialis, the main concern with binge drinking is a sudden drop in blood pressure, known as orthostatic hypotension

When it comes to alcohol, less is always safer, especially when other medications are involved. 

Alcohol and Sexual Health

If mixing Cialis and alcohol is a concern for you, it might be worth exploring how alcohol affects our sexual health. Research shows that persistent alcohol use is directly linked to sexual dysfunction, ranging from decreased libido to physical difficulties. If that’s the case, could quitting alcohol help resolve the need for Cialis? Let’s find out.

There are many different causes of ED, from illness to medications to emotional issues. Whatever the reason, alcohol can make matters worse.


  • Alcohol is a depressant. Alcohol slows down the central nervous system, which slows down the chemical messengers that travel from the brain to other parts of the body. This is why our speech slurs and our feet stumble. Likewise, alcohol can make it difficult for a man to get or maintain an erection.

  • Alcohol affects testosterone levels. While small amounts of alcohol can increase testosterone (and libido), studies show that heavy or chronic alcohol use can decrease testosterone, leading to sexual dysfunction.

  • Alcohol affects fertility. Sexual dysfunction alone can interfere with fertility, but heavy alcohol use also diminishes sperm quality, making it more difficult to conceive. This can be good news for some, but it can be devastating news for those who are trying to conceive. 

  • Alcohol affects relationships. While “hookup culture” might make it appear that alcohol boosts your sex life, real relationships affected by alcohol misuse tell us otherwise. Studies have shown that heavy alcohol use decreases relationship satisfaction and increases marital distress, neither of which is conducive to a healthy sex life. 

To sum up, while we can’t say that quitting or even cutting back on alcohol will cure ED, we can confidently say it will help. 

Safely Improve Sexual Health

Fortunately, there are things you can do to stay safe while your mind adjusts to a new way of thinking. 


  • Take Cialis as prescribed. Nothing less, nothing more. For every guideline and warning on a prescription label, there’s a study or incident to back it up. Don’t find out the hard way why they are there.
  • Plan carefully. When you’re planning a date that involves drinking, plan out the timing of your drinks (and meals) so there’s not much in your system when it’s time to take Cialis. 
  • Know the signs of low blood pressure. If you’re drinking while taking Cialis, pay attention to your body’s signals. If you get a headache or start feeling dizzy, stop drinking and find a place to sit down as soon as possible to avoid falling.
  • Eat and sleep well. A healthy diet and sleep pattern can both affect hormone levels, stress levels, and other factors that can contribute to ED. Better overall health will lead to better sexual health. 
  • Limit alcohol intake. If alcohol has become a third wheel (or worse — the main character) on all your dates, it might be time to reconsider or “reframe” your relationship with it. Reframe is here to guide you every step of the way with neuroscience-backed programs to help you reach your goals. 


Above all, be sure to repair and/or nourish your relationships, whether they be sexual or not. Stronger relationships lead to greater satisfaction and well-being in all areas of your life. 

Alcohol and Cialis in Sum

While mixing alcohol and Cialis isn’t inherently life-threatening, it could lead to dangerous blood pressure fluctuations. Furthermore, alcohol could counteract the effects of Cialis. If you’re looking to improve your sexual health, nourish your body with good sleep and nutrition, and nurture the relationships that mean the most to you. And as always, pay close attention to new symptoms and seek medical advice when needed. We’re here to help and cheer you on!

Alcohol and Medications
2024-11-22 9:00
Alcohol and Medications
Can You Take Paxlovid and Alcohol Together?
This is some text inside of a div block.

Can you drink alcohol with Paxlovid? As it turns out, the mix could be risky and might set you up for a longer recovery from COVID. Find out more in our latest blog!

22 min read

Protect Your Hormones by Drinking Less With Reframe!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet hundreds of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!

Read Full Article  →

Back in December 2019 in the city of Wuhan, China, a few patients came down with an “atypical pneumonia-like illness that does not respond well to standard treatments.” The rest, as we know it, is history.

The COVID pandemic will live on in history books as a major world disaster, but for most of us, it was an everyday reality. Caused by the coronavirus SARS-CoV-2 that triggered severe respiratory symptoms (and was deadly to vulnerable populations), the pandemic turned our lives upside down, leading to lockdowns, social distancing, mask-wearing, and rigorous hygiene practices.

We stocked up on toilet paper and Lysol wipes, cleared out grocery store shelves of everything from canned soup to asparagus, and waited anxiously for updates from officials who, for a long time, knew as little as the rest of us about the situation.

In all the chaos and confusion, a lot of people turned to booze to deal with the stress of it all. When Paxlovid came out, it left many wondering: can you drink alcohol while taking Paxlovid? In this article, we’ll explore the link between Paxlovid, alcohol, and liver and kidney problems.

Paxlovid to the Rescue

A glass of alcohol beside a cup filled with various pills

“If it’s COVID, Paxlovid.” This catchy slogan aired to promote the new “wonder drug” said to diminish COVID symptoms. It wasn’t a cure, but it was pretty close. With Paxlovid, the outlook for COVID patients changed considerably. They could ride it out at home with enough energy to play video games in the living room or type away on a laptop. They were still sick, but they were getting better.

How Does Paxlovid Work?

Paxlovid combines 2 medicines — nirmatrelvir and ritonavir — to throw a wrench in the virus’s attack on the body. Nirmatrelvir stops it from growing and spreading while keeping its levels to a minimum by blocking a specific enzyme, robbing the virus of its ability to multiply. The second member of the antiviral duo is there for support, keeping nirmatrelvir from getting metabolized by the liver, giving it enough time to do its job.

Who Is Paxlovid Meant For?

Paxlovid is for those at risk of developing severe COVID symptoms. And while many of us might say, “That’s not me, I’m healthy,” at least 75% of U.S. adults have at least one risk factor that puts them in this category. Here are the most common ones:

  • Being 50 or older (those over 65 are especially vulnerable)
  • Having a condition such as cancer, diabetes, or heart disease
  • Being overweight
  • Being pregnant
  • Having a weakened immune system
  • Having a mental health disorder
  • Being unvaccinated or not up to date on COVID vaccines
  • Having certain disabilities

According to the CDC, certain life circumstances also put us in a higher risk category. For example, where we live or work and access to healthcare can make a difference.

Can You Drink Alcohol While Taking Paxlovid?

How does it interact with alcohol? Let’s explore what happens when we mix alcohol and Paxlovid.

1. Side Effects of Paxlovid and Alcohol

For one thing, alcohol can amp up many of the side effects of Paxlovid. And when we’re already battling an infection that’s uncomfortable (to say the least), extra obstacles are the last thing we need. Let’s dig deeper into what we can expect from the Paxlovid-alcohol combo.

  • Increased blood pressure. This is certainly one to pay special attention to, especially if we have preexisting heart issues. Alcohol is hard on the heart, causing an increased heart rate and blood pressure fluctuations that can be dangerous if mixed with Paxlovid.
  • Gastrointestinal problems. One of the most common side effects of Paxlovid is stomach discomfort in the form of abdominal pain, nausea, or diarrhea. With alcohol in the mix, things can get, well, queasier. Even if we don’t take it to the extreme, booze can make us nauseous or send us running for the restroom on an off night. Why risk it?
  • Dehydration. This is another big one. With COVID depleting us of much-needed water and electrolytes we need when we’re recovering, our focus should be on hydration. Instead, alcohol does the opposite by telling our kidneys to let loose, leading to further dehydration as we lose water throughout the night and wake up parched and shaky the next morning. 
  • Muscle aches. It’s a fact that tends to slip under the radar: alcohol can cause muscle problems. So if our muscles are aching after a night of drinking, we don’t need to search our memory for any impromptu jumping jacks or sprints we may have done the night before — chances are, it’s the booze. And since Paxlovid also causes muscle soreness, we double the trouble by mixing the two.
  • An altered or impaired sense of taste. Many of us have experienced the weird games COVID plays with our taste buds, and Paxlovid tends to add some bitter notes to the mix. Alcohol doesn’t help matters any — despite what many people say about the way it “complements” certain foods, it suppresses our sense of taste. The result? Everything (including that chicken soup we need for the nutrients) tastes even more bland. 
  • Feeling generally unwell. That overall malaise feeling that Paxlovid can sometimes bring on? Well, booze will make it worse, especially if we overdo it. Just think back to that last hangover.

All in all, the picture that emerges is clear: if it’s COVID, Paxlovid (but not booze). 

2. Paxlovid, Alcohol, Liver, and Kidneys

Paxlovid is cleared by the kidneys, but it can also cause liver strain in people who are dealing with serious liver disease or are on dialysis. For everyone else, the FDA cautions to be on the lookout for signs of liver problems, such as appetite loss, jaundice (a yellow tinge to the skin and the whites of the eyes), dark urine, itchy skin, and stomach issues. 

Adding alcohol to the mix can only make matters worse. It’s notoriously rough on the liver, which is at the frontlines of processing alcohol. Since nirmatrelvir competes with alcohol for metabolism, our liver can easily be overworked. But the kidneys aren’t immune to the effects either: in fact, heavy drinking is linked to kidney disease.

Staying Safe When Recovering From COVID and Beyond

3. Alcohol, Immunity, and Lung Health

Moreover, alcohol can do a number on our immune system and lungs, which doesn’t help matters when it comes to fighting off a deadly respiratory virus.

  • Alcohol causes inflammation. We all know how flammable alcohol is — many first attempts at a flambéed dessert have ended in accidentally setting off a fire alarm. But as it turns out, alcohol can also stoke the metaphorical “fire” of our immune system. Alcohol can lead to chronic inflammation by disrupting the delicate balance of microbiota in our gut.  
  • Drinking interferes with our ability to fight off infections. Drinking — especially heavily — takes a toll on our innate and acquired immune system functions. The result? We’re more susceptible to getting sick in the first place — that pesky cold that seems to come after a weekend of heavy drinking isn’t a coincidence!
  • Alcohol can damage the epithelial lining of the lungs. While we normally associate alcohol misuse with liver and heart problems, it can also wreak havoc on the lungs. In fact, alcohol is one of the main culprits behind acute respiratory distress syndrome (ARDS). It would make sense that weakened lungs make it harder to fight off a respiratory virus, especially one that affects epithelial tissues in particular. Moreover, studies also show that alcohol consumption increases our risk of contracting COVID to begin with. Plus, alcohol can make asthma symptoms worse, further contributing to the risk if we do contract COVID.
  • Drinking can make recovery more difficult. Finally, dealing with the aftermath of a serious infection such as COVID takes all the power our body can muster, and alcohol doesn’t help matters. By introducing a toxin to our system, we make recovery take longer.

Want to learn more about how alcohol affects our immunity? Check out “Alcohol's Impact on the Immune System.”

4. COVID: The “Long” Story

Moreover, there’s the issue of “Long COVID” to consider. As if “regular” COVID wasn't enough, this “enhanced” version started rearing its ugly head as many of us found ourselves feeling drained, fatigued, and emotionally unwell for weeks or even months battling through the acute infection.

This dreaded lengthy stay of the virus was precisely what Paxlovid was meant to address. But if we add alcohol to the picture, things can get a bit more complicated.

  • Alcohol is a depressant. Depression can be a difficult side of Long COVID, and alcohol won’t make it any better. As a depressant, it tends to intensify symptoms of low mood and low energy that often go hand in hand.
  • Alcohol increases mental fog. Brain fog is another symptom we might be facing, and booze will certainly take this one up a notch. Alcohol impairs thinking as our prefrontal cortex takes a temporary break, and if we’re already not feeling as sharp as we’re used to, we’re inviting more confusion and frustration.
  • Alcohol increases fatigue, especially in the long run. While alcohol tends to make us doze off initially, it actually disrupts our sleep and robs us of the most restorative sleep stages. The result? Next-day fatigue. And with Long COVID in the picture, it could be that much harder to get out of bed in the morning.

As we can see, alcohol is likely to stand in the way of our recovery, and there’s no point in making Long COVID last even longer.

COVID, Paxlovid, and Alcohol: The Bigger Picture

As it turns out, however, the relationship between alcohol and COVID goes beyond the Paxlovid-alcohol interactions. For many of us, COVID itself became (on top of everything else) an unexpected trigger for drinking. And it’s not hard to see why.

Some of us were cooped up indoors with rambunctious toddlers, moody teenagers, and spouses (who, lovely as they might be, are usually not in our faces 24/7). Others had the opposite dilemma, finding themselves isolated for weeks that turned into months. If we happened to see a neighbor on one of our toilet paper runs to the store, we probably wouldn’t have recognized them in their face mask from six feet away.

At the same time, home delivery of everything from the aforementioned toilet paper to, yes, alcohol, skyrocketed. The result? Our drinking habits did too. 

Drinking During COVID: The Stats

Statistics around the country back this up. According to the NIH, a rise in drinking during times of crisis is common, as shown by data after the 1993 World Trade Center bombing, Hurricane Katrina, and 9/11. During the first year of the pandemic, alcohol sales saw the largest increase in half a century (around 3%). Many studies showed that about a quarter of the population drank more than before due to the stress and uncertainty of the situation. 

Unfortunately, this meant that hospitalizations and deaths from alcohol misuse added to the already soaring casualty rates from COVID. According to George F. Koob, director of the National Institute on Alcohol Abuse and Alcoholism, the first two years brought about a 38% increase in death certificates listing alcohol as a contributing cause, with the largest increase affecting people in the 25-44 age bracket. 

Alcohol-related injuries became more frequent and the demand for liver transplants grew, with record-breaking numbers of patients under the age of 30. Regrettably, many ended up waiting in vain: deaths from liver disease went up by more than 22% during these already difficult years. (To learn more about the effects of COVID on alcohol use, take a look at “How Has Alcohol Use Changed After the COVID-19 Pandemic?”)

Staying Safe When Recovering From COVID and Beyond

So how can we stay safe when we’re taking Paxlovid? And how can we avoid the deeper pitfalls of alcohol misuse triggered by the pandemic itself? Here are some tips to consider:

  1. Avoid the Paxlovid-alcohol mix. If you’re taking Paxlovid, stay away from booze for the time being. It’s not worth the risk of complications and prolonging your recovery.
  2. Nourish your body. Even if eating is the last thing on your mind, your body needs nourishment. Stick to small, simple meals (the BRAT diet of bread, rice, apples, and toast is great if you’re having stomach issues), and stay away from rich or spicy food.
  3. Stay hydrated. If you're nauseous from taking Paxlovid, take small sips or add some electrolyte powder for flavoring.
  4. Rethink the drink in the long term. If you’re finding that the COVID pandemic got your drinking habits out of whack, consider taking a longer break. You might just find that a life with less alcohol is well worth it. In addition to better sleep, a healthier heart and liver, a faster metabolism, and clearer skin, you can stave off future infections with the help of a stronger immune system.

And remember, there are millions of others around the world who have been where you are and know how you feel. Connect to them and swap stories and advice through the Reframe 24/7 Forum! The journey is more fun and more rewarding when you can share it with others like you.

A New Chapter

In the end, the pandemic made us rethink a lot of our daily habits. And if alcohol is one of them, so be it — let’s take this opportunity to revamp our relationship with it to be healthier, happier, and COVID-free.

Back in December 2019 in the city of Wuhan, China, a few patients came down with an “atypical pneumonia-like illness that does not respond well to standard treatments.” The rest, as we know it, is history.

The COVID pandemic will live on in history books as a major world disaster, but for most of us, it was an everyday reality. Caused by the coronavirus SARS-CoV-2 that triggered severe respiratory symptoms (and was deadly to vulnerable populations), the pandemic turned our lives upside down, leading to lockdowns, social distancing, mask-wearing, and rigorous hygiene practices.

We stocked up on toilet paper and Lysol wipes, cleared out grocery store shelves of everything from canned soup to asparagus, and waited anxiously for updates from officials who, for a long time, knew as little as the rest of us about the situation.

In all the chaos and confusion, a lot of people turned to booze to deal with the stress of it all. When Paxlovid came out, it left many wondering: can you drink alcohol while taking Paxlovid? In this article, we’ll explore the link between Paxlovid, alcohol, and liver and kidney problems.

Paxlovid to the Rescue

A glass of alcohol beside a cup filled with various pills

“If it’s COVID, Paxlovid.” This catchy slogan aired to promote the new “wonder drug” said to diminish COVID symptoms. It wasn’t a cure, but it was pretty close. With Paxlovid, the outlook for COVID patients changed considerably. They could ride it out at home with enough energy to play video games in the living room or type away on a laptop. They were still sick, but they were getting better.

How Does Paxlovid Work?

Paxlovid combines 2 medicines — nirmatrelvir and ritonavir — to throw a wrench in the virus’s attack on the body. Nirmatrelvir stops it from growing and spreading while keeping its levels to a minimum by blocking a specific enzyme, robbing the virus of its ability to multiply. The second member of the antiviral duo is there for support, keeping nirmatrelvir from getting metabolized by the liver, giving it enough time to do its job.

Who Is Paxlovid Meant For?

Paxlovid is for those at risk of developing severe COVID symptoms. And while many of us might say, “That’s not me, I’m healthy,” at least 75% of U.S. adults have at least one risk factor that puts them in this category. Here are the most common ones:

  • Being 50 or older (those over 65 are especially vulnerable)
  • Having a condition such as cancer, diabetes, or heart disease
  • Being overweight
  • Being pregnant
  • Having a weakened immune system
  • Having a mental health disorder
  • Being unvaccinated or not up to date on COVID vaccines
  • Having certain disabilities

According to the CDC, certain life circumstances also put us in a higher risk category. For example, where we live or work and access to healthcare can make a difference.

Can You Drink Alcohol While Taking Paxlovid?

How does it interact with alcohol? Let’s explore what happens when we mix alcohol and Paxlovid.

1. Side Effects of Paxlovid and Alcohol

For one thing, alcohol can amp up many of the side effects of Paxlovid. And when we’re already battling an infection that’s uncomfortable (to say the least), extra obstacles are the last thing we need. Let’s dig deeper into what we can expect from the Paxlovid-alcohol combo.

  • Increased blood pressure. This is certainly one to pay special attention to, especially if we have preexisting heart issues. Alcohol is hard on the heart, causing an increased heart rate and blood pressure fluctuations that can be dangerous if mixed with Paxlovid.
  • Gastrointestinal problems. One of the most common side effects of Paxlovid is stomach discomfort in the form of abdominal pain, nausea, or diarrhea. With alcohol in the mix, things can get, well, queasier. Even if we don’t take it to the extreme, booze can make us nauseous or send us running for the restroom on an off night. Why risk it?
  • Dehydration. This is another big one. With COVID depleting us of much-needed water and electrolytes we need when we’re recovering, our focus should be on hydration. Instead, alcohol does the opposite by telling our kidneys to let loose, leading to further dehydration as we lose water throughout the night and wake up parched and shaky the next morning. 
  • Muscle aches. It’s a fact that tends to slip under the radar: alcohol can cause muscle problems. So if our muscles are aching after a night of drinking, we don’t need to search our memory for any impromptu jumping jacks or sprints we may have done the night before — chances are, it’s the booze. And since Paxlovid also causes muscle soreness, we double the trouble by mixing the two.
  • An altered or impaired sense of taste. Many of us have experienced the weird games COVID plays with our taste buds, and Paxlovid tends to add some bitter notes to the mix. Alcohol doesn’t help matters any — despite what many people say about the way it “complements” certain foods, it suppresses our sense of taste. The result? Everything (including that chicken soup we need for the nutrients) tastes even more bland. 
  • Feeling generally unwell. That overall malaise feeling that Paxlovid can sometimes bring on? Well, booze will make it worse, especially if we overdo it. Just think back to that last hangover.

All in all, the picture that emerges is clear: if it’s COVID, Paxlovid (but not booze). 

2. Paxlovid, Alcohol, Liver, and Kidneys

Paxlovid is cleared by the kidneys, but it can also cause liver strain in people who are dealing with serious liver disease or are on dialysis. For everyone else, the FDA cautions to be on the lookout for signs of liver problems, such as appetite loss, jaundice (a yellow tinge to the skin and the whites of the eyes), dark urine, itchy skin, and stomach issues. 

Adding alcohol to the mix can only make matters worse. It’s notoriously rough on the liver, which is at the frontlines of processing alcohol. Since nirmatrelvir competes with alcohol for metabolism, our liver can easily be overworked. But the kidneys aren’t immune to the effects either: in fact, heavy drinking is linked to kidney disease.

Staying Safe When Recovering From COVID and Beyond

3. Alcohol, Immunity, and Lung Health

Moreover, alcohol can do a number on our immune system and lungs, which doesn’t help matters when it comes to fighting off a deadly respiratory virus.

  • Alcohol causes inflammation. We all know how flammable alcohol is — many first attempts at a flambéed dessert have ended in accidentally setting off a fire alarm. But as it turns out, alcohol can also stoke the metaphorical “fire” of our immune system. Alcohol can lead to chronic inflammation by disrupting the delicate balance of microbiota in our gut.  
  • Drinking interferes with our ability to fight off infections. Drinking — especially heavily — takes a toll on our innate and acquired immune system functions. The result? We’re more susceptible to getting sick in the first place — that pesky cold that seems to come after a weekend of heavy drinking isn’t a coincidence!
  • Alcohol can damage the epithelial lining of the lungs. While we normally associate alcohol misuse with liver and heart problems, it can also wreak havoc on the lungs. In fact, alcohol is one of the main culprits behind acute respiratory distress syndrome (ARDS). It would make sense that weakened lungs make it harder to fight off a respiratory virus, especially one that affects epithelial tissues in particular. Moreover, studies also show that alcohol consumption increases our risk of contracting COVID to begin with. Plus, alcohol can make asthma symptoms worse, further contributing to the risk if we do contract COVID.
  • Drinking can make recovery more difficult. Finally, dealing with the aftermath of a serious infection such as COVID takes all the power our body can muster, and alcohol doesn’t help matters. By introducing a toxin to our system, we make recovery take longer.

Want to learn more about how alcohol affects our immunity? Check out “Alcohol's Impact on the Immune System.”

4. COVID: The “Long” Story

Moreover, there’s the issue of “Long COVID” to consider. As if “regular” COVID wasn't enough, this “enhanced” version started rearing its ugly head as many of us found ourselves feeling drained, fatigued, and emotionally unwell for weeks or even months battling through the acute infection.

This dreaded lengthy stay of the virus was precisely what Paxlovid was meant to address. But if we add alcohol to the picture, things can get a bit more complicated.

  • Alcohol is a depressant. Depression can be a difficult side of Long COVID, and alcohol won’t make it any better. As a depressant, it tends to intensify symptoms of low mood and low energy that often go hand in hand.
  • Alcohol increases mental fog. Brain fog is another symptom we might be facing, and booze will certainly take this one up a notch. Alcohol impairs thinking as our prefrontal cortex takes a temporary break, and if we’re already not feeling as sharp as we’re used to, we’re inviting more confusion and frustration.
  • Alcohol increases fatigue, especially in the long run. While alcohol tends to make us doze off initially, it actually disrupts our sleep and robs us of the most restorative sleep stages. The result? Next-day fatigue. And with Long COVID in the picture, it could be that much harder to get out of bed in the morning.

As we can see, alcohol is likely to stand in the way of our recovery, and there’s no point in making Long COVID last even longer.

COVID, Paxlovid, and Alcohol: The Bigger Picture

As it turns out, however, the relationship between alcohol and COVID goes beyond the Paxlovid-alcohol interactions. For many of us, COVID itself became (on top of everything else) an unexpected trigger for drinking. And it’s not hard to see why.

Some of us were cooped up indoors with rambunctious toddlers, moody teenagers, and spouses (who, lovely as they might be, are usually not in our faces 24/7). Others had the opposite dilemma, finding themselves isolated for weeks that turned into months. If we happened to see a neighbor on one of our toilet paper runs to the store, we probably wouldn’t have recognized them in their face mask from six feet away.

At the same time, home delivery of everything from the aforementioned toilet paper to, yes, alcohol, skyrocketed. The result? Our drinking habits did too. 

Drinking During COVID: The Stats

Statistics around the country back this up. According to the NIH, a rise in drinking during times of crisis is common, as shown by data after the 1993 World Trade Center bombing, Hurricane Katrina, and 9/11. During the first year of the pandemic, alcohol sales saw the largest increase in half a century (around 3%). Many studies showed that about a quarter of the population drank more than before due to the stress and uncertainty of the situation. 

Unfortunately, this meant that hospitalizations and deaths from alcohol misuse added to the already soaring casualty rates from COVID. According to George F. Koob, director of the National Institute on Alcohol Abuse and Alcoholism, the first two years brought about a 38% increase in death certificates listing alcohol as a contributing cause, with the largest increase affecting people in the 25-44 age bracket. 

Alcohol-related injuries became more frequent and the demand for liver transplants grew, with record-breaking numbers of patients under the age of 30. Regrettably, many ended up waiting in vain: deaths from liver disease went up by more than 22% during these already difficult years. (To learn more about the effects of COVID on alcohol use, take a look at “How Has Alcohol Use Changed After the COVID-19 Pandemic?”)

Staying Safe When Recovering From COVID and Beyond

So how can we stay safe when we’re taking Paxlovid? And how can we avoid the deeper pitfalls of alcohol misuse triggered by the pandemic itself? Here are some tips to consider:

  1. Avoid the Paxlovid-alcohol mix. If you’re taking Paxlovid, stay away from booze for the time being. It’s not worth the risk of complications and prolonging your recovery.
  2. Nourish your body. Even if eating is the last thing on your mind, your body needs nourishment. Stick to small, simple meals (the BRAT diet of bread, rice, apples, and toast is great if you’re having stomach issues), and stay away from rich or spicy food.
  3. Stay hydrated. If you're nauseous from taking Paxlovid, take small sips or add some electrolyte powder for flavoring.
  4. Rethink the drink in the long term. If you’re finding that the COVID pandemic got your drinking habits out of whack, consider taking a longer break. You might just find that a life with less alcohol is well worth it. In addition to better sleep, a healthier heart and liver, a faster metabolism, and clearer skin, you can stave off future infections with the help of a stronger immune system.

And remember, there are millions of others around the world who have been where you are and know how you feel. Connect to them and swap stories and advice through the Reframe 24/7 Forum! The journey is more fun and more rewarding when you can share it with others like you.

A New Chapter

In the end, the pandemic made us rethink a lot of our daily habits. And if alcohol is one of them, so be it — let’s take this opportunity to revamp our relationship with it to be healthier, happier, and COVID-free.

Alcohol and Medications
2024-11-06 9:00
Alcohol and Medications
Wegovy and Alcohol: All We Need To Know
This is some text inside of a div block.

Is drinking on Wegovy a bad idea? Between increased side effects and alcohol sabotaging your weight loss efforts, science says it’s risky. Learn more in our latest blog!

19 min read

Lose Weight and Drink Less With Reframe!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet hundreds of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!

Read Full Article  →

Picture this: you’ve tried it all. You’ve been measuring your yogurt and granola religiously, swinging those kettlebells every morning (watch out for the glass table!), and even made Calorie King your homepage. And yet the scale isn’t budging.

Whatever the reason, these days there are medications that can help get the weight loss process going. A new one that’s been making waves is Wegovy — the brand-name version of semaglutide, which has become one of the go-to meds prescribed for weight loss. But you might be wondering, what about mixing Wegovy and alcohol — can you drink on Wegovy? Or is it a no-go? Let’s find out!

What Is Wegovy?

Wegovy was originally developed to treat type 2 diabetes — a condition caused by our body’s inability to use insulin, a hormone that moves glucose (our primary source of energy) from our blood into our cells. According to the CDC, diabetes affects around 38.4 million people in the U.S. — a whopping 11.6% of the U.S. population. Sometimes we can chalk it up to the luck of the genetic draw: one form of diabetes — type 1 — is an inherited autoimmune disease. Type 2 diabetes, on the other hand, develops over time and is the fallout of unhealthy eating habits and a sedentary lifestyle.

And while being overweight isn’t a “prerequisite” for diabetes, obesity and diabetes share some biological features, and benefit from the same treatment. 

Wegovy belongs to a class of drugs known as GLP-1 receptor agonists. GLP-1 is a hormone that helps us regulate blood sugar levels and appetite. In its natural form, GLP-1 gets released by the gut after we eat and binds to GLP-1 receptors in the brain and pancreas, triggering insulin release while making us feel full. GLP-1 receptor agonists such as Wegovy step in to do the same: research shows that Wegovy promotes insulin release while making it easier to keep a lid on our snacking habits.

The Dopamine Dilemma: Wegovy Reduces Alcohol’s Effects

First things first: we might find that taking Wegovy curbs our desire to drink altogether. The reason has to do with the brain. Wegovy works by altering pathways in the hypothalamus — a region that regulates hunger and satiety. As it turns out, it also plays a key role in the reward system that’s at the center of addictive behaviors such as alcohol misuse.

Alcohol hijacks the reward system by artificially boosting dopamine — a neurotransmitter associated with pleasure that’s also involved in motivation and learning. While the reward system evolved to allow us to develop habits necessary for survival — for example, eating or finding a romantic partner — substances such as alcohol trigger dopamine release artificially. That’s what makes it so hard to stop!

Wegovy, in turn, tweaks the reward system pathways in a way that makes alcohol less potent. We don’t get the same “high,” so we’re not as tempted to keep coming back for more. In fact, studies have even shown that Wegovy could be used to curb drinking!

That said, what happens if we do decide to mix alcohol and Wegovy?

Can You Drink on Wegovy?

We’ve established that our cravings for booze might naturally simmer down when Wegovy is in the mix. But what if they don’t? Can you drink alcohol on Wegovy? Mixing the two could spell trouble for a number of reasons.

1. Increased Risk of Hypoglycemia

If we do mix alcohol and Wegovy, the result isn’t pretty. For one thing, our blood sugar levels could go out of whack. While alcohol increases blood sugar in the long run, the immediate effect is usually a blood sugar drop. Because the body sees alcohol as a poison and prioritizes its metabolism over everything else, it stops releasing glucose — causing a temporary dip in blood sugar.

Because semaglutide lowers our blood sugar as well, we’re in for an all-time low when we combine Wegovy and alcohol. The result? We might feel dizzy, confused, or even pass out. 

2. Increased Side Effects

But that’s not all! Like any medication, Wegovy is not without its side effects.

What are Wegovy side effects with alcohol? Here’s what we might be in store for if we combine the two:

  • Gastrointestinal trouble. Wegovy can mess with our stomach, and alcohol is known to do the same. Both can lead to nausea, vomiting, and diarrhea — and a night that quickly goes down the drain as well.
  • Dehydration. Yes, alcohol is a liquid, but it’s a sneaky one. By suppressing vasopressin — the hormone that tells our kidneys to hold on to water — it leads to frequent trips to the bathroom throughout the night and dehydration the next morning. Wegovy can also cause dehydration and add to the problem, making us more parched than ever.
  • Cardiovascular glitches. Both Wegovy and alcohol increase our heart rate — an effect that’s especially troublesome if we have a preexisting heart condition. Besides, alcohol also leads to blood pressure spikes and cardiomyopathy over time, adding to the strain. 
  • Danger to the pancreas. In some cases, Wegovy can be hard on the pancreas. With alcohol in the picture, the risk of pancreatic damage gets even higher.
  • Anxiety. It’s not just our physical health that’s in question when it comes to mixing alcohol and Wegovy. While less common than other effects, anxiety can be one of the side effects of semaglutide. And while alcohol initially dampens anxiety through its downer effects, more often than not the rebound effect caused by the brain’s attempt to rebalance itself leaves us feeling more anxious than before we took that drink to “calm our nerves.” 

It’s clear that combining Wegovy side effects with alcohol’s impact makes for an unpleasant — and possibly dangerous — combination. Drinking on Wegovy is likely to cause trouble, especially if we overdo it.

3. Impact on Weight Loss

Last but certainly not least, here’s one of the most important reasons why alcohol and Wegovy are a problematic pair: booze can sabotage our weight loss efforts, throwing a wrench in the progress we’ve made, and maybe even sending us back to the state that led us to start taking the medication in the first place. Here’s why the two play for opposite teams:

  • Alcohol is full of empty calories. Alcohol is second only to fats when it comes to the number of calories per gram. A single drink can pack as much as a large slice of pizza or bowl of ice cream! (For example, a piña colada can have over 500 calories per serving, while an eggnog with rum has about 400.)
  • It makes us hungry. As anyone who has ever had a craving for pizza after a boozy night can attest to, alcohol often makes us hungry — and usually not for broccoli or low-fat cottage cheese. This wave of hunger comes because alcohol amps up the “hunger hormone” ghrelin, making us feel ravenous even if we’ve had enough to eat. And with our inhibitions lowered, we’re less likely to make healthy choices as we raid the fridge (or reach for our phone to order delivery).
  • It messes with our metabolism. Over time, alcohol also throws a wrench in the workings of our metabolism, making it more sluggish. It’s certainly not what we want, especially when we’re on a weight loss journey. (For more information, check out “Does Alcohol Slow Metabolism?.”)
  • It interferes with sleep. Last but not least, alcohol robs us of the restorative powers of sleep, which is essential for sustainable weight loss. While it might make us initially sleepy, it robs us of the most restorative REM stages of sleep and often results in fragmented slumber in the second half of the night. The result? Our hunger increases even more, since lack of sleep is associated with an increase in ghrelin. Plus, sleep deprivation contributes to higher levels of the stress hormone cortisol, further sabotaging our weight loss efforts.

It’s best to steer clear of alcohol while on Wegovy. This not only helps us with our weight loss but promotes a healthier lifestyle all around.

Wegovy and Alcohol Tips for the Journey

Wegovy and Alcohol: Tips for the Journey

It can feel challenging to navigate the weight loss journey while also trying to drink less. The great news is that the same tools can make both goals easier to reach. Here are some of the most effective ones: 

  • Track your patterns. First things first: it’s important to become familiar with your triggers around food and alcohol. When do you feel the urge to drink? How does it affect your eating patterns? And how do you feel afterwards? Remember — this isn’t about judgment. Instead, you’re gathering important information: bringing your habits into conscious awareness is essential to undoing their power. 
  • Make a plan. Once you have an idea of what your patterns are, it’s time to make a plan! If you do drink, decide exactly how much you’re going to have and share your plan with an accountability buddy to keep yourself accountable.
  • Add more movement. Exercise is a key part of the weight loss journey, but it can also be a powerful way to keep your drinking in check! Science says that physical activity releases endorphins and reduces stress, keeping our cravings at bay.
  • Get a mindfulness practice going. Mindfulness — conscious awareness of the world around us without judgment — is another “superpower” when it comes to the weight loss journey and alcohol reduction alike. Science says it boosts neuroplasticity — the brain’s ability to rewire itself — and allows us to observe our cravings without giving in. (Want to learn more? Check out “Using Mindfulness Practices to Enhance Self-Awareness and Promote Healthier Drinking Habits.”)
  • Coast through cravings. In addition to exercise and mindfulness, there are many other techniques — for example, distraction, visualization, or the STOP method — that can make it easier to coast through cravings for alcohol and unhealthy food choices. Pick up some tips from “How To Stop Alcohol Cravings” and “How Urge Surfing Can Help You Overcome Alcohol Cravings” to become an urge-surfing pro!

And remember, the Reframe community is here to help you every step of the way. Check out our vibrant 24/7 Forum where others who’ve been in your shoes and know what it’s like are ready to share their stories and advice. We’re rooting for you!

Summing Up

Whether or not we’re taking Wegovy, quitting alcohol will only help our weight loss efforts. Losing weight and reducing alcohol intake both involve being mindful of what we put in our body, and as we adjust our habits, we can look forward to a healthier, more vibrant lifestyle!

Picture this: you’ve tried it all. You’ve been measuring your yogurt and granola religiously, swinging those kettlebells every morning (watch out for the glass table!), and even made Calorie King your homepage. And yet the scale isn’t budging.

Whatever the reason, these days there are medications that can help get the weight loss process going. A new one that’s been making waves is Wegovy — the brand-name version of semaglutide, which has become one of the go-to meds prescribed for weight loss. But you might be wondering, what about mixing Wegovy and alcohol — can you drink on Wegovy? Or is it a no-go? Let’s find out!

What Is Wegovy?

Wegovy was originally developed to treat type 2 diabetes — a condition caused by our body’s inability to use insulin, a hormone that moves glucose (our primary source of energy) from our blood into our cells. According to the CDC, diabetes affects around 38.4 million people in the U.S. — a whopping 11.6% of the U.S. population. Sometimes we can chalk it up to the luck of the genetic draw: one form of diabetes — type 1 — is an inherited autoimmune disease. Type 2 diabetes, on the other hand, develops over time and is the fallout of unhealthy eating habits and a sedentary lifestyle.

And while being overweight isn’t a “prerequisite” for diabetes, obesity and diabetes share some biological features, and benefit from the same treatment. 

Wegovy belongs to a class of drugs known as GLP-1 receptor agonists. GLP-1 is a hormone that helps us regulate blood sugar levels and appetite. In its natural form, GLP-1 gets released by the gut after we eat and binds to GLP-1 receptors in the brain and pancreas, triggering insulin release while making us feel full. GLP-1 receptor agonists such as Wegovy step in to do the same: research shows that Wegovy promotes insulin release while making it easier to keep a lid on our snacking habits.

The Dopamine Dilemma: Wegovy Reduces Alcohol’s Effects

First things first: we might find that taking Wegovy curbs our desire to drink altogether. The reason has to do with the brain. Wegovy works by altering pathways in the hypothalamus — a region that regulates hunger and satiety. As it turns out, it also plays a key role in the reward system that’s at the center of addictive behaviors such as alcohol misuse.

Alcohol hijacks the reward system by artificially boosting dopamine — a neurotransmitter associated with pleasure that’s also involved in motivation and learning. While the reward system evolved to allow us to develop habits necessary for survival — for example, eating or finding a romantic partner — substances such as alcohol trigger dopamine release artificially. That’s what makes it so hard to stop!

Wegovy, in turn, tweaks the reward system pathways in a way that makes alcohol less potent. We don’t get the same “high,” so we’re not as tempted to keep coming back for more. In fact, studies have even shown that Wegovy could be used to curb drinking!

That said, what happens if we do decide to mix alcohol and Wegovy?

Can You Drink on Wegovy?

We’ve established that our cravings for booze might naturally simmer down when Wegovy is in the mix. But what if they don’t? Can you drink alcohol on Wegovy? Mixing the two could spell trouble for a number of reasons.

1. Increased Risk of Hypoglycemia

If we do mix alcohol and Wegovy, the result isn’t pretty. For one thing, our blood sugar levels could go out of whack. While alcohol increases blood sugar in the long run, the immediate effect is usually a blood sugar drop. Because the body sees alcohol as a poison and prioritizes its metabolism over everything else, it stops releasing glucose — causing a temporary dip in blood sugar.

Because semaglutide lowers our blood sugar as well, we’re in for an all-time low when we combine Wegovy and alcohol. The result? We might feel dizzy, confused, or even pass out. 

2. Increased Side Effects

But that’s not all! Like any medication, Wegovy is not without its side effects.

What are Wegovy side effects with alcohol? Here’s what we might be in store for if we combine the two:

  • Gastrointestinal trouble. Wegovy can mess with our stomach, and alcohol is known to do the same. Both can lead to nausea, vomiting, and diarrhea — and a night that quickly goes down the drain as well.
  • Dehydration. Yes, alcohol is a liquid, but it’s a sneaky one. By suppressing vasopressin — the hormone that tells our kidneys to hold on to water — it leads to frequent trips to the bathroom throughout the night and dehydration the next morning. Wegovy can also cause dehydration and add to the problem, making us more parched than ever.
  • Cardiovascular glitches. Both Wegovy and alcohol increase our heart rate — an effect that’s especially troublesome if we have a preexisting heart condition. Besides, alcohol also leads to blood pressure spikes and cardiomyopathy over time, adding to the strain. 
  • Danger to the pancreas. In some cases, Wegovy can be hard on the pancreas. With alcohol in the picture, the risk of pancreatic damage gets even higher.
  • Anxiety. It’s not just our physical health that’s in question when it comes to mixing alcohol and Wegovy. While less common than other effects, anxiety can be one of the side effects of semaglutide. And while alcohol initially dampens anxiety through its downer effects, more often than not the rebound effect caused by the brain’s attempt to rebalance itself leaves us feeling more anxious than before we took that drink to “calm our nerves.” 

It’s clear that combining Wegovy side effects with alcohol’s impact makes for an unpleasant — and possibly dangerous — combination. Drinking on Wegovy is likely to cause trouble, especially if we overdo it.

3. Impact on Weight Loss

Last but certainly not least, here’s one of the most important reasons why alcohol and Wegovy are a problematic pair: booze can sabotage our weight loss efforts, throwing a wrench in the progress we’ve made, and maybe even sending us back to the state that led us to start taking the medication in the first place. Here’s why the two play for opposite teams:

  • Alcohol is full of empty calories. Alcohol is second only to fats when it comes to the number of calories per gram. A single drink can pack as much as a large slice of pizza or bowl of ice cream! (For example, a piña colada can have over 500 calories per serving, while an eggnog with rum has about 400.)
  • It makes us hungry. As anyone who has ever had a craving for pizza after a boozy night can attest to, alcohol often makes us hungry — and usually not for broccoli or low-fat cottage cheese. This wave of hunger comes because alcohol amps up the “hunger hormone” ghrelin, making us feel ravenous even if we’ve had enough to eat. And with our inhibitions lowered, we’re less likely to make healthy choices as we raid the fridge (or reach for our phone to order delivery).
  • It messes with our metabolism. Over time, alcohol also throws a wrench in the workings of our metabolism, making it more sluggish. It’s certainly not what we want, especially when we’re on a weight loss journey. (For more information, check out “Does Alcohol Slow Metabolism?.”)
  • It interferes with sleep. Last but not least, alcohol robs us of the restorative powers of sleep, which is essential for sustainable weight loss. While it might make us initially sleepy, it robs us of the most restorative REM stages of sleep and often results in fragmented slumber in the second half of the night. The result? Our hunger increases even more, since lack of sleep is associated with an increase in ghrelin. Plus, sleep deprivation contributes to higher levels of the stress hormone cortisol, further sabotaging our weight loss efforts.

It’s best to steer clear of alcohol while on Wegovy. This not only helps us with our weight loss but promotes a healthier lifestyle all around.

Wegovy and Alcohol Tips for the Journey

Wegovy and Alcohol: Tips for the Journey

It can feel challenging to navigate the weight loss journey while also trying to drink less. The great news is that the same tools can make both goals easier to reach. Here are some of the most effective ones: 

  • Track your patterns. First things first: it’s important to become familiar with your triggers around food and alcohol. When do you feel the urge to drink? How does it affect your eating patterns? And how do you feel afterwards? Remember — this isn’t about judgment. Instead, you’re gathering important information: bringing your habits into conscious awareness is essential to undoing their power. 
  • Make a plan. Once you have an idea of what your patterns are, it’s time to make a plan! If you do drink, decide exactly how much you’re going to have and share your plan with an accountability buddy to keep yourself accountable.
  • Add more movement. Exercise is a key part of the weight loss journey, but it can also be a powerful way to keep your drinking in check! Science says that physical activity releases endorphins and reduces stress, keeping our cravings at bay.
  • Get a mindfulness practice going. Mindfulness — conscious awareness of the world around us without judgment — is another “superpower” when it comes to the weight loss journey and alcohol reduction alike. Science says it boosts neuroplasticity — the brain’s ability to rewire itself — and allows us to observe our cravings without giving in. (Want to learn more? Check out “Using Mindfulness Practices to Enhance Self-Awareness and Promote Healthier Drinking Habits.”)
  • Coast through cravings. In addition to exercise and mindfulness, there are many other techniques — for example, distraction, visualization, or the STOP method — that can make it easier to coast through cravings for alcohol and unhealthy food choices. Pick up some tips from “How To Stop Alcohol Cravings” and “How Urge Surfing Can Help You Overcome Alcohol Cravings” to become an urge-surfing pro!

And remember, the Reframe community is here to help you every step of the way. Check out our vibrant 24/7 Forum where others who’ve been in your shoes and know what it’s like are ready to share their stories and advice. We’re rooting for you!

Summing Up

Whether or not we’re taking Wegovy, quitting alcohol will only help our weight loss efforts. Losing weight and reducing alcohol intake both involve being mindful of what we put in our body, and as we adjust our habits, we can look forward to a healthier, more vibrant lifestyle!

Alcohol and Medications
2024-10-05 9:00
Alcohol and Medications
Can You Drink After Taking Excedrin?
This is some text inside of a div block.

Alcohol and Excedrin work against each other and are dangerous when mixed. Check out our latest blog for more info on the specific interactions when mixing the two.

16 min read

Avoid Dangerous Side Effects With Help From Reframe!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet hundreds of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!

Read Full Article  →

You’re headed out to a friend’s birthday dinner, but you feel a migraine coming on. You take Excedrin before leaving the house to make sure you won’t be miserable throughout the night. During dinner, everyone orders a drink, and you may be wondering if you can join in. 

Your migraine may be at bay, but having a drink while taking Excedrin still isn’t a good idea. Let’s examine how alcohol and Excedrin interact to understand why mixing the two can be a recipe for disaster.

Excedrin: A Migraine Mitigator 

A man grimaces as he clutches his head

Excedrin is an over-the-counter pain medication used specifically to treat migraines and tension headaches. The medication is made of a combination of three main components: 

  • Acetaminophen. Commonly known as Tylenol, acetaminophen is a pain reliever and fever reducer. It reduces the amount of prostaglandins (hormone-like compounds) produced. A decrease in prostaglandins increases the amount of pain our body can tolerate.
  • Aspirin. Aspirin is a nonsteroidal, anti-inflammatory (NSAID) drug that reduces pain and inflammation. It also reduces prostaglandins but through different mechanisms. 
  • Caffeine. Caffeine is a vasoconstrictor, which means that it narrows our blood vessels. This helps to combat headaches that can occur when our blood vessels widen.

Together, the three components work together to mitigate migraines and tension headaches, distinguishing Excedrin from other pain medications.  

Alcohol’s Connection to Migraines

Alcohol is a common trigger for migraines due to the numerous factors:

  • Diuretic properties. Alcohol is a diuretic, meaning that it promotes excess elimination of fluid from the body. This can lead to dehydration, which is a known trigger for migraines. Alcohol is also a vasodilator, which means that it causes the blood vessels in our brain to expand. This is the main reason that drinking is often associated with pounding headaches. For those of us who are sensitive to migraines, alcohol’s vasodilation effects can be a trigger.
  • Congeners. As byproducts of alcohol from fermentation or distillation, congeners can be found in some dark alcohols such as wines and whiskeys. These chemicals are associated with worse headaches and can trigger migraines, which is why some of us get the dreaded “wine hangover” after having a glass. 
  • Sleep disruptions. Another way that alcohol can trigger migraines is through disruption of our sleep patterns. Poor sleep and migraines can often start a feedback loop. Lack of sleep can trigger migraines, which can then affect our sleep. 

As we can see, alcohol is directly linked to an increased risk of migraines, as it sets the scene. So if we take Excedrin to ease our migraines, does it cancel out the negative effects of alcohol?

Can You Take Excedrin With Alcohol?

On the contrary, alcohol can interact with all three components of Excedrin — making it even more dangerous than mixing alcohol with each of the ingredients on its own. Alcohol, acetaminophen, and aspirin are all broken down by our mighty liver. However, our liver can only do so much at once. 

  • Alcohol and acetaminophen. When mixing alcohol and acetaminophen, our liver will be overworked — increasing the risks of harm from toxins in alcohol and the harmful byproducts of the medication. 
  • Alcohol and aspirin. Similarly, alcohol will also interact with the breakdown of aspirin, leading to higher levels of medication found in our blood which can produce greater adverse effects. 
  • Alcohol and caffeine. Even though caffeine and alcoholic beverages are frequently mixed, they can be a dangerous duo. Alcohol is a depressant but can have stimulant effects while drinking. The two have overlapping effects and, when combined, they can amplify side effects such as increased heart rate and dehydration. 

Since alcohol interacts with all three active ingredients in Excedrin, drinking can cause serious consequences. 

Can You Take Excedrin After Drinking?

Excedrin isn’t recommended to be taken before, during, or after drinking. Both substances stay in our body for much longer than when they’re first consumed. This means that even though some time may have passed since we started drinking, alcohol can still be in our body and negatively interact with Excedrin. 

We all metabolize alcohol differently, and the time it takes our body to break down and eliminate alcohol can differ from person to person, depending on factors such as the amount of alcohol and the timeframe in which it was consumed. In general, it takes about an hour to metabolize a standard drink. However, since this changes depending on many factors, it’s difficult to determine an exact timeframe, so it’s best to err on the side of caution. 

Can You Drink After Taking Excedrin?

Our migraine may be going away after taking Excedrin, so we may be wondering when it’s okay to drink. As with alcohol, the medication takes time to be metabolized and eliminated from our system. 

The half-life of Excedrin is 10 hours. This means that it takes about 10 hours for half of the medication to be eliminated. For it to be completely eliminated, it can take a minimum of 20 hours. To be safe, it’s recommended to wait at least 24-48 hours after taking Excedrin to drink.

Drinking after taking Excedrin can also increase the risk of triggering another migraine. Although we may feel better after taking the medication, Excedrin could just be suppressing symptoms. Drinking alcohol, a known migraine trigger, could aggravate symptoms that can become even more severe once the medication subsides. If we’ve already accidentally had a drink, should we panic? 

How Much Is Too Much?

It’s best to avoid all alcohol when taking Excedrin. That being said, if we drink, it’s best to wait an hour for each standard drink we consume. This can minimize the adverse effects and give our body time to metabolize each of the substances separately. However, it’s important to note that the “one standard drink per hour” rule is an average and may not be the same for everyone. In addition, two or three standard drinks in one hour can overload our liver and drastically change everything. 

To avoid any adverse effects, the best course of action is to avoid mixing alcohol and Excedrin. 

Negative Effects of Mixing Alcohol and Excedrin

Alcohol and Excedrin have direct interactions that can lead to serious effects:

  • Nausea and vomiting. GI discomfort is a possible side effect of Excedrin. This overlaps with the symptoms of intoxication — increasing the chances of nausea and vomiting.
  • Stomach ulcers. Ulcers are a listed side effect of Excedrin. Alcohol’s negative impact on our stomach lining can increase the risk of stomach ulcers.
  • Stomach bleeding. NSAIDs like the aspirin in Excedrin are associated with possible upper GI bleeding. With the blood thinning effects of alcohol, this dangerous effect is even more common.
  • Increased liver damage. Toxic byproducts of Excedrin and the toxic compound in alcohol, acetaldehyde, are both metabolized primarily by our liver. When taken together, our liver becomes overloaded and increasingly susceptible to damage. 
  • Rapid heartbeat. Alcohol and components of Excedrin such as caffeine can both cause an increased heart rate. When combined, this effect can be amplified. 

Now that we’ve determined that mixing the two can be dangerous, how long should we wait between them?

Negative Effects of Mixing Excedrin and Alcohol

What To Do If You Mix Excedrin and Alcohol

There’s no need to panic if we accidentally mix the two, but it’s best to stop drinking immediately and take the proper precautions:

  • Monitor symptoms. Since alcohol and Excedrin are associated with their own side effects, keeping track of any symptoms we experience can help us determine if we should seek medical treatment. This can also help us understand more about how alcohol can affect our migraines.
  • Stay hydrated. Drinking plenty of water can help our cells and organs function optimally to metabolize alcohol and Excedrin efficiently. It can also help to combat dehydration. 
  • Seek medical treatment. Mixing alcohol and Excedrin can cause severe side effects. If you experience any worrisome symptoms, dial 911 and seek emergency medical treatment immediately. 

Migraines can be debilitating. Mixing a treatment and trigger for migraines is a recipe for disaster. So, how can we approach drinking and Excedrin safely?

Approaching Alcohol and Excedrin Safely 

There’s no “safe” way to drink while taking Excedrin. However, implementing mindful drinking practices can help reduce the risk of harmful consequences:

  • Avoid alcohol. Avoiding alcohol can prevent the dangerous effects of mixing alcohol and Excedrin. It also prevents alcohol-related triggers — improving the occurrence of our migraines. 
  • Find alternatives. Alcohol-free alternatives can help us keep the party going without the risks of interactions between Excedrin and alcohol. Mix up a cocktail with an electrolyte-rich beverage to stay hydrated and keep those migraine symptoms from returning.
  • Migraine management. Lifestyle changes through avoiding individual triggers can limit the need for Excedrin to treat symptoms. It also reminds us to quit or cut back on alcohol, which can help us reduce additional triggers.
  • Prioritize liver health. One of the main consequences of mixing Excedrin and alcohol is liver damage. Maintaining our liver health through regular exercise, a balanced diet, and limiting toxic substances can help with our overall health and well-being.

These mindful practices will limit interactions between Excedrin and alcohol and help us better manage our migraines.

The Bottom Line

Excedrin is made of a specific combination of ingredients that make it an effective pain reliever for migraines and tension headaches. Alcohol not only acts as a trigger for migraines, which Excedrin is used to treat but also directly interacts with all three components of the medication — leading to potentially dangerous symptoms. Avoiding drinking not only prevents the adverse effects of mixing alcohol and Excedrin but also minimizes triggers for migraines. Skip the champagne (and all alcohol for that matter) and avoid a migraine! 

You’re headed out to a friend’s birthday dinner, but you feel a migraine coming on. You take Excedrin before leaving the house to make sure you won’t be miserable throughout the night. During dinner, everyone orders a drink, and you may be wondering if you can join in. 

Your migraine may be at bay, but having a drink while taking Excedrin still isn’t a good idea. Let’s examine how alcohol and Excedrin interact to understand why mixing the two can be a recipe for disaster.

Excedrin: A Migraine Mitigator 

A man grimaces as he clutches his head

Excedrin is an over-the-counter pain medication used specifically to treat migraines and tension headaches. The medication is made of a combination of three main components: 

  • Acetaminophen. Commonly known as Tylenol, acetaminophen is a pain reliever and fever reducer. It reduces the amount of prostaglandins (hormone-like compounds) produced. A decrease in prostaglandins increases the amount of pain our body can tolerate.
  • Aspirin. Aspirin is a nonsteroidal, anti-inflammatory (NSAID) drug that reduces pain and inflammation. It also reduces prostaglandins but through different mechanisms. 
  • Caffeine. Caffeine is a vasoconstrictor, which means that it narrows our blood vessels. This helps to combat headaches that can occur when our blood vessels widen.

Together, the three components work together to mitigate migraines and tension headaches, distinguishing Excedrin from other pain medications.  

Alcohol’s Connection to Migraines

Alcohol is a common trigger for migraines due to the numerous factors:

  • Diuretic properties. Alcohol is a diuretic, meaning that it promotes excess elimination of fluid from the body. This can lead to dehydration, which is a known trigger for migraines. Alcohol is also a vasodilator, which means that it causes the blood vessels in our brain to expand. This is the main reason that drinking is often associated with pounding headaches. For those of us who are sensitive to migraines, alcohol’s vasodilation effects can be a trigger.
  • Congeners. As byproducts of alcohol from fermentation or distillation, congeners can be found in some dark alcohols such as wines and whiskeys. These chemicals are associated with worse headaches and can trigger migraines, which is why some of us get the dreaded “wine hangover” after having a glass. 
  • Sleep disruptions. Another way that alcohol can trigger migraines is through disruption of our sleep patterns. Poor sleep and migraines can often start a feedback loop. Lack of sleep can trigger migraines, which can then affect our sleep. 

As we can see, alcohol is directly linked to an increased risk of migraines, as it sets the scene. So if we take Excedrin to ease our migraines, does it cancel out the negative effects of alcohol?

Can You Take Excedrin With Alcohol?

On the contrary, alcohol can interact with all three components of Excedrin — making it even more dangerous than mixing alcohol with each of the ingredients on its own. Alcohol, acetaminophen, and aspirin are all broken down by our mighty liver. However, our liver can only do so much at once. 

  • Alcohol and acetaminophen. When mixing alcohol and acetaminophen, our liver will be overworked — increasing the risks of harm from toxins in alcohol and the harmful byproducts of the medication. 
  • Alcohol and aspirin. Similarly, alcohol will also interact with the breakdown of aspirin, leading to higher levels of medication found in our blood which can produce greater adverse effects. 
  • Alcohol and caffeine. Even though caffeine and alcoholic beverages are frequently mixed, they can be a dangerous duo. Alcohol is a depressant but can have stimulant effects while drinking. The two have overlapping effects and, when combined, they can amplify side effects such as increased heart rate and dehydration. 

Since alcohol interacts with all three active ingredients in Excedrin, drinking can cause serious consequences. 

Can You Take Excedrin After Drinking?

Excedrin isn’t recommended to be taken before, during, or after drinking. Both substances stay in our body for much longer than when they’re first consumed. This means that even though some time may have passed since we started drinking, alcohol can still be in our body and negatively interact with Excedrin. 

We all metabolize alcohol differently, and the time it takes our body to break down and eliminate alcohol can differ from person to person, depending on factors such as the amount of alcohol and the timeframe in which it was consumed. In general, it takes about an hour to metabolize a standard drink. However, since this changes depending on many factors, it’s difficult to determine an exact timeframe, so it’s best to err on the side of caution. 

Can You Drink After Taking Excedrin?

Our migraine may be going away after taking Excedrin, so we may be wondering when it’s okay to drink. As with alcohol, the medication takes time to be metabolized and eliminated from our system. 

The half-life of Excedrin is 10 hours. This means that it takes about 10 hours for half of the medication to be eliminated. For it to be completely eliminated, it can take a minimum of 20 hours. To be safe, it’s recommended to wait at least 24-48 hours after taking Excedrin to drink.

Drinking after taking Excedrin can also increase the risk of triggering another migraine. Although we may feel better after taking the medication, Excedrin could just be suppressing symptoms. Drinking alcohol, a known migraine trigger, could aggravate symptoms that can become even more severe once the medication subsides. If we’ve already accidentally had a drink, should we panic? 

How Much Is Too Much?

It’s best to avoid all alcohol when taking Excedrin. That being said, if we drink, it’s best to wait an hour for each standard drink we consume. This can minimize the adverse effects and give our body time to metabolize each of the substances separately. However, it’s important to note that the “one standard drink per hour” rule is an average and may not be the same for everyone. In addition, two or three standard drinks in one hour can overload our liver and drastically change everything. 

To avoid any adverse effects, the best course of action is to avoid mixing alcohol and Excedrin. 

Negative Effects of Mixing Alcohol and Excedrin

Alcohol and Excedrin have direct interactions that can lead to serious effects:

  • Nausea and vomiting. GI discomfort is a possible side effect of Excedrin. This overlaps with the symptoms of intoxication — increasing the chances of nausea and vomiting.
  • Stomach ulcers. Ulcers are a listed side effect of Excedrin. Alcohol’s negative impact on our stomach lining can increase the risk of stomach ulcers.
  • Stomach bleeding. NSAIDs like the aspirin in Excedrin are associated with possible upper GI bleeding. With the blood thinning effects of alcohol, this dangerous effect is even more common.
  • Increased liver damage. Toxic byproducts of Excedrin and the toxic compound in alcohol, acetaldehyde, are both metabolized primarily by our liver. When taken together, our liver becomes overloaded and increasingly susceptible to damage. 
  • Rapid heartbeat. Alcohol and components of Excedrin such as caffeine can both cause an increased heart rate. When combined, this effect can be amplified. 

Now that we’ve determined that mixing the two can be dangerous, how long should we wait between them?

Negative Effects of Mixing Excedrin and Alcohol

What To Do If You Mix Excedrin and Alcohol

There’s no need to panic if we accidentally mix the two, but it’s best to stop drinking immediately and take the proper precautions:

  • Monitor symptoms. Since alcohol and Excedrin are associated with their own side effects, keeping track of any symptoms we experience can help us determine if we should seek medical treatment. This can also help us understand more about how alcohol can affect our migraines.
  • Stay hydrated. Drinking plenty of water can help our cells and organs function optimally to metabolize alcohol and Excedrin efficiently. It can also help to combat dehydration. 
  • Seek medical treatment. Mixing alcohol and Excedrin can cause severe side effects. If you experience any worrisome symptoms, dial 911 and seek emergency medical treatment immediately. 

Migraines can be debilitating. Mixing a treatment and trigger for migraines is a recipe for disaster. So, how can we approach drinking and Excedrin safely?

Approaching Alcohol and Excedrin Safely 

There’s no “safe” way to drink while taking Excedrin. However, implementing mindful drinking practices can help reduce the risk of harmful consequences:

  • Avoid alcohol. Avoiding alcohol can prevent the dangerous effects of mixing alcohol and Excedrin. It also prevents alcohol-related triggers — improving the occurrence of our migraines. 
  • Find alternatives. Alcohol-free alternatives can help us keep the party going without the risks of interactions between Excedrin and alcohol. Mix up a cocktail with an electrolyte-rich beverage to stay hydrated and keep those migraine symptoms from returning.
  • Migraine management. Lifestyle changes through avoiding individual triggers can limit the need for Excedrin to treat symptoms. It also reminds us to quit or cut back on alcohol, which can help us reduce additional triggers.
  • Prioritize liver health. One of the main consequences of mixing Excedrin and alcohol is liver damage. Maintaining our liver health through regular exercise, a balanced diet, and limiting toxic substances can help with our overall health and well-being.

These mindful practices will limit interactions between Excedrin and alcohol and help us better manage our migraines.

The Bottom Line

Excedrin is made of a specific combination of ingredients that make it an effective pain reliever for migraines and tension headaches. Alcohol not only acts as a trigger for migraines, which Excedrin is used to treat but also directly interacts with all three components of the medication — leading to potentially dangerous symptoms. Avoiding drinking not only prevents the adverse effects of mixing alcohol and Excedrin but also minimizes triggers for migraines. Skip the champagne (and all alcohol for that matter) and avoid a migraine! 

Alcohol and Medications
2024-08-28 9:00
Alcohol and Medications
The Risks of Mixing Librium and Alcohol
This is some text inside of a div block.

Wondering if Librium and alcohol are dangerous to mix? Read about the risks in our latest blog and stay safe!

21 min read

Feel Better by Drinking Less With Reframe!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet hundreds of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!

Read Full Article  →

Alcohol withdrawal is no picnic — and that’s putting it lightly. If you’ve ever gone through it, you know what it’s like to be covered in sweat (yet shivering at the same time), unable to hold a pen for enough seconds in a row to sign your name, all the while doubling over with that never-ending nausea that no amount of Liquid IV, Melba crackers, or ginger chews seem to quell. Yuck. And it’s even worse at night, when you’re lying in bed, stuck in that queasy in-between space of insomnia and extreme fatigue. 

Luckily, these days we have Librium to help us out when the situation calls for it. While it was originally developed to treat anxiety, these days it’s primarily used to treat alcohol withdrawal. But what happens if you mix Librium with alcohol? Let’s look into the harmful effects of mixing these two substances.

What Is Librium?

A glass of liquor accompanied by a bowl of pills

Had history taken a different turn, Librium could have gone undiscovered, tossed into a garbage can at the Hoffmann-La Roche labs in New Jersey in 1954. As the story goes, it was discovered by accident when scientist Leo Sternbach started tinkering with a class of heretofore unknown compounds dubbed “benzheptoxdiazines.” He helped synthesize these compounds 20 years earlier but couldn’t derive any pharmacological use out of them. One of the versions he came up with — a crystalline powder labeled “Ro 5-0690” —  ended up on the shelf (and almost in the garbage can, when Sternbach’s lab was getting cleaned over a year later).

As you may have guessed, this was the first version of Librium — a compound that ended up having powerful hypnotic and sedative effects in mice and acted as a potent muscle relaxer in cats. Soon enough this early benzodiazepine passed clinical trials and went from relaxing felines to quelling anxiety and insomnia in humans. Unfortunately, it also made people slur their words and lose coordination, so the interest in the drug fizzled out until it was picked up by other investigators who had better luck and eventually got it approved by the FDA in 1960.

How Does Librium Work?

Remember those slurring and stumbling early Librium patients? When we look at how Librium works at a chemical level, it’s not surprising that they seemed, well, drunk. 

Just like alcohol, Librium works by enhancing the effects of a neurotransmitter in the brain called gamma-aminobutyric acid (GABA), which helps to calm nervous-system activity. Alcohol does the same (along with suppressing glutamate, its excitatory counterpart).

The result? Relaxation and tranquility. Exactly what we need when our brain chemistry is going haywire during withdrawal. Why? Because the brain is all about balance. If we’ve been drinking for a while, it gets used to the flood of GABA and suppresses its natural production. Switching gears suddenly doesn’t give it time to adjust, so replenishing our GABA with the help of Librium during the transition period makes for a much smoother ride.

The Benzo Scene Gets Bigger

Time went on, and benzodiazepines evolved as Valium, Klonopin, and Xanax came onto the scene. While these days they’re usually given preference when it comes to treating anxiety disorders, Librium has become the go-to medication for treating alcohol withdrawal (as well as presurgery anxiety).

Librium and Alcohol: A Dangerous Mix

Although it’s effective for alcohol withdrawal, taking Librium with alcohol is a whole different story.

In short, it’s not a good idea — and it could be dangerous. Here’s why:

1. Increased Sedation

Both Librium and alcohol are depressants that slow down the nervous system. Librium itself can cause severe drowsiness, slowing our heart rate and breathing to potentially dangerous levels.

When we mix the two substances, the downer effects get even more risky. The sedative properties are enhanced, potentially causing dangerous levels of respiratory depression, drowsiness, and dizziness. Even if we don’t stop breathing, the dizziness alone can pose a risk, especially if we’re out and about, crossing streets or operating machinery.

2. Other Side Effects

Librium has other side effects that don’t mix well with alcohol:

  • Cognitive problems. Librium can make our memory fuzzy while throwing our concentration off-kilter. And alcohol? Well, let’s just say we’re not at our sharpest after we’ve had a few drinks.
  • Mood swings. Librium is known to cause unusual changes in mood or behavior. As for alcohol, we know it can make our mood unpredictable as well, getting us to laugh at a weather report on TV one minute and cry at a shampoo commercial the next. These mood swings can persist well into the next day, so any overlap between Librium is trouble waiting to happen.
  • Balance and coordination problems. As we mentioned before, both Librium and alcohol can make us dizzy. Added to that, there are possible problems with balance or muscle movement — in other words, an accident waiting to happen.
  • Digestive side effects. While less dangerous than the other side effects, this one can still be a nuisance. Librium could cause stomach pain and loss of appetite. Alcohol, in turn, wreaks havoc on the digestive system, causing stomach irritation (that could turn into gastritis if we really overdo it for a while), discomfort, bloating, diarrhea, or constipation. Not fun!

As we can see, the side effects of Librium don’t combine well with the effects of booze. But there’s even more to the story! 

3. Risk to the Liver

Both alcohol and Librium are processed by the liver, and as we know, the liver is already working overtime to process booze, so adding to its already full plate is asking for trouble. 

Besides, if we’ve been drinking for a long time (let’s face it, that’s usually the context in which we get introduced to Librium to begin with), we might already be showing signs of liver disease, such as fatty liver or even cirrhosis. So let’s give it a break! (For more information, check out “How Much Alcohol Causes Liver Damage?”)

4. Increased Risk of Overdose

Another risk of mixing Librium with booze? We’re playing with danger when it comes to potential overdose risk. Taking both together makes overdose more likely than taking either substance alone. Here are the telltale symptoms:

  • We might feel confused.
  • Our motor skills go out the window.
  • We could feel lethargic and sleepy (but watch out — “sleeping it off” could be deadly!)

If things progress, we could end up in a coma or worse. Never ignore the signs of an overdose — seek medical help right away!

5. Risk of Mental Health Problems and Dependence

Last but not least, both Librium and alcohol can lead to dependence. In addition to causing a surge of GABA, both trigger the release of dopamine — the so-called “reward neurotransmitter.” As the name suggests, dopamine makes us feel good — it’s a neurological “gold star” our brain rewards us with when we perform a habitual action. 

While the reward system evolved to keep habits alive in order to ensure our survival, unfortunately it can’t distinguish between beneficial habits (such as socializing or eating nutritious foods) or destructive ones (such as substance use, gambling, and any other number of habits that also trigger a rush of dopamine).

With both Librium and alcohol in our system, we become more likely to fall into habitual use of either or both substances. We are also more prone to act impulsively, ending up embarrassed at best and possibly putting ourselves in serious danger. (Driving under the influence, jumping into the pool in the middle of December — whatever it is, we’re more likely to do it.) Want to know more about how dependence develops? Take a look at  “Understanding Alcohol Dependence: Health Issues, Causes, and How To Overcome.”

How Long After Taking Librium Can I Drink Alcohol?

Most doctors recommend waiting to make sure Librium is completely out of your system before considering drinking. With a long half-life that ranges anywhere from 5 to 30 hours, some of Librium’s metabolites remain in the system for quite a while, so it’s best to wait at least a few days.

That said, there might be additional considerations to keep in mind when weighing whether drinking after taking Librium is a good idea, even if it’s been a few days. If you were taking Librium for alcohol withdrawal, adding booze back into your life so soon afterwards (or at all) might not be in your best interests. Always check with your doctor first, and stick to the treatment plan you’ve chosen together!

Alcohol Withdrawal and Librium

Alcohol withdrawal can be an incredibly challenging experience, both physically and mentally, for those grappling with dependence. When someone decides to quit drinking after prolonged heavy use, their body and brain often struggle to adjust to the sudden absence of alcohol. Symptoms range from mild anxiety and tremors to severe complications like seizures and hallucinations. 

In medical settings, managing these symptoms effectively is crucial, and Librium is often used to alleviate some of these uncomfortable symptoms. Librium’s calming effects help mitigate the intensity of withdrawal symptoms, providing a safer and more comfortable transition towards sobriety. However, it's important for individuals undergoing alcohol withdrawal to be under medical supervision, as the dosage and duration of Librium treatment need careful monitoring to prevent dependence on this medication.

Mixing Librium and alcohol can be extremely dangerous due to their combined depressant effects on the central nervous system. Both substances slow down brain activity and cause drowsiness, dizziness, impaired coordination, and memory problems. When taken together, they amplify each other's negative impacts. This combination increases the risk of accidents, falls, and other injuries. Moreover, mixing Librium and alcohol can lead to dangerously low blood pressure, slowed breathing, and even coma in severe cases. Additionally, both substances can be habit-forming on their own, and combining them increases the likelihood of developing dependence and addiction.

It is crucial for individuals prescribed Librium to avoid alcohol completely during treatment and to follow their healthcare provider's instructions carefully to ensure safe and effective recovery

Tips To Stay Safe

Finally, here are some tips to stay safe while taking Librium (as well as advice for coping with withdrawal):

  1. Avoid the mix. First and foremost, don’t mix Librium and alcohol — it’s not worth the risk!
  2. Ask for help if you need to. There’s no shame in asking for help — in fact, it’s a sign of strength! If you’re struggling with dependency of any kind, going through withdrawal, or trying to cut back on alcohol and are having trouble, you’re not alone. Many others (such as members of the Reframe community!) have been exactly where you are and are now thriving. Reach out, and we’ll be happy to help! 
  3. Find your people. Once you find people you jibe with — whether it’s online or in person — cultivate those relationships. You’ll need a “tribe” to rely on throughout your journey, and it takes time to really get to know someone. Trust us, it’ll be worth it!
  4. Nourish your body. Whether you’re going through alcohol withdrawal, trying to cut back, or just want to feel your best, nourishing your body is key. Make sure you get plenty of whole grains, healthy fats, and lean proteins in your diet. And load up on those vitamin-rich fruits and veggies! Your body will thank you.
  5. Get moving. Make sure you’re doing some gentle movement every day. Yoga, walking, swimming, dancing in your living room — whatever floats your boat. All of it counts, and all of it will be a step in the right direction, as far as recovery is concerned.
  6. Get rest and take it easy. That closet remodeling project can wait. Make sure you’re getting plenty of rest as your body recovers! Alcohol robs us of much-needed quality sleep, which is essential for restoring health.

And remember, Reframe is here for you as you navigate your relationship with alcohol. Join our thriving community and hear the stories of others who have been exactly where you are and know what it’s like. We wish you the best and are here to support you every step of the way.

Summing Up

All in all, deciding to take a break from booze — especially if Librium is in the picture — might open up exciting new possibilities. Let’s not look at it as deprivation and instead get curious about exploring life beyond booze. There’s so much to discover!

Alcohol withdrawal is no picnic — and that’s putting it lightly. If you’ve ever gone through it, you know what it’s like to be covered in sweat (yet shivering at the same time), unable to hold a pen for enough seconds in a row to sign your name, all the while doubling over with that never-ending nausea that no amount of Liquid IV, Melba crackers, or ginger chews seem to quell. Yuck. And it’s even worse at night, when you’re lying in bed, stuck in that queasy in-between space of insomnia and extreme fatigue. 

Luckily, these days we have Librium to help us out when the situation calls for it. While it was originally developed to treat anxiety, these days it’s primarily used to treat alcohol withdrawal. But what happens if you mix Librium with alcohol? Let’s look into the harmful effects of mixing these two substances.

What Is Librium?

A glass of liquor accompanied by a bowl of pills

Had history taken a different turn, Librium could have gone undiscovered, tossed into a garbage can at the Hoffmann-La Roche labs in New Jersey in 1954. As the story goes, it was discovered by accident when scientist Leo Sternbach started tinkering with a class of heretofore unknown compounds dubbed “benzheptoxdiazines.” He helped synthesize these compounds 20 years earlier but couldn’t derive any pharmacological use out of them. One of the versions he came up with — a crystalline powder labeled “Ro 5-0690” —  ended up on the shelf (and almost in the garbage can, when Sternbach’s lab was getting cleaned over a year later).

As you may have guessed, this was the first version of Librium — a compound that ended up having powerful hypnotic and sedative effects in mice and acted as a potent muscle relaxer in cats. Soon enough this early benzodiazepine passed clinical trials and went from relaxing felines to quelling anxiety and insomnia in humans. Unfortunately, it also made people slur their words and lose coordination, so the interest in the drug fizzled out until it was picked up by other investigators who had better luck and eventually got it approved by the FDA in 1960.

How Does Librium Work?

Remember those slurring and stumbling early Librium patients? When we look at how Librium works at a chemical level, it’s not surprising that they seemed, well, drunk. 

Just like alcohol, Librium works by enhancing the effects of a neurotransmitter in the brain called gamma-aminobutyric acid (GABA), which helps to calm nervous-system activity. Alcohol does the same (along with suppressing glutamate, its excitatory counterpart).

The result? Relaxation and tranquility. Exactly what we need when our brain chemistry is going haywire during withdrawal. Why? Because the brain is all about balance. If we’ve been drinking for a while, it gets used to the flood of GABA and suppresses its natural production. Switching gears suddenly doesn’t give it time to adjust, so replenishing our GABA with the help of Librium during the transition period makes for a much smoother ride.

The Benzo Scene Gets Bigger

Time went on, and benzodiazepines evolved as Valium, Klonopin, and Xanax came onto the scene. While these days they’re usually given preference when it comes to treating anxiety disorders, Librium has become the go-to medication for treating alcohol withdrawal (as well as presurgery anxiety).

Librium and Alcohol: A Dangerous Mix

Although it’s effective for alcohol withdrawal, taking Librium with alcohol is a whole different story.

In short, it’s not a good idea — and it could be dangerous. Here’s why:

1. Increased Sedation

Both Librium and alcohol are depressants that slow down the nervous system. Librium itself can cause severe drowsiness, slowing our heart rate and breathing to potentially dangerous levels.

When we mix the two substances, the downer effects get even more risky. The sedative properties are enhanced, potentially causing dangerous levels of respiratory depression, drowsiness, and dizziness. Even if we don’t stop breathing, the dizziness alone can pose a risk, especially if we’re out and about, crossing streets or operating machinery.

2. Other Side Effects

Librium has other side effects that don’t mix well with alcohol:

  • Cognitive problems. Librium can make our memory fuzzy while throwing our concentration off-kilter. And alcohol? Well, let’s just say we’re not at our sharpest after we’ve had a few drinks.
  • Mood swings. Librium is known to cause unusual changes in mood or behavior. As for alcohol, we know it can make our mood unpredictable as well, getting us to laugh at a weather report on TV one minute and cry at a shampoo commercial the next. These mood swings can persist well into the next day, so any overlap between Librium is trouble waiting to happen.
  • Balance and coordination problems. As we mentioned before, both Librium and alcohol can make us dizzy. Added to that, there are possible problems with balance or muscle movement — in other words, an accident waiting to happen.
  • Digestive side effects. While less dangerous than the other side effects, this one can still be a nuisance. Librium could cause stomach pain and loss of appetite. Alcohol, in turn, wreaks havoc on the digestive system, causing stomach irritation (that could turn into gastritis if we really overdo it for a while), discomfort, bloating, diarrhea, or constipation. Not fun!

As we can see, the side effects of Librium don’t combine well with the effects of booze. But there’s even more to the story! 

3. Risk to the Liver

Both alcohol and Librium are processed by the liver, and as we know, the liver is already working overtime to process booze, so adding to its already full plate is asking for trouble. 

Besides, if we’ve been drinking for a long time (let’s face it, that’s usually the context in which we get introduced to Librium to begin with), we might already be showing signs of liver disease, such as fatty liver or even cirrhosis. So let’s give it a break! (For more information, check out “How Much Alcohol Causes Liver Damage?”)

4. Increased Risk of Overdose

Another risk of mixing Librium with booze? We’re playing with danger when it comes to potential overdose risk. Taking both together makes overdose more likely than taking either substance alone. Here are the telltale symptoms:

  • We might feel confused.
  • Our motor skills go out the window.
  • We could feel lethargic and sleepy (but watch out — “sleeping it off” could be deadly!)

If things progress, we could end up in a coma or worse. Never ignore the signs of an overdose — seek medical help right away!

5. Risk of Mental Health Problems and Dependence

Last but not least, both Librium and alcohol can lead to dependence. In addition to causing a surge of GABA, both trigger the release of dopamine — the so-called “reward neurotransmitter.” As the name suggests, dopamine makes us feel good — it’s a neurological “gold star” our brain rewards us with when we perform a habitual action. 

While the reward system evolved to keep habits alive in order to ensure our survival, unfortunately it can’t distinguish between beneficial habits (such as socializing or eating nutritious foods) or destructive ones (such as substance use, gambling, and any other number of habits that also trigger a rush of dopamine).

With both Librium and alcohol in our system, we become more likely to fall into habitual use of either or both substances. We are also more prone to act impulsively, ending up embarrassed at best and possibly putting ourselves in serious danger. (Driving under the influence, jumping into the pool in the middle of December — whatever it is, we’re more likely to do it.) Want to know more about how dependence develops? Take a look at  “Understanding Alcohol Dependence: Health Issues, Causes, and How To Overcome.”

How Long After Taking Librium Can I Drink Alcohol?

Most doctors recommend waiting to make sure Librium is completely out of your system before considering drinking. With a long half-life that ranges anywhere from 5 to 30 hours, some of Librium’s metabolites remain in the system for quite a while, so it’s best to wait at least a few days.

That said, there might be additional considerations to keep in mind when weighing whether drinking after taking Librium is a good idea, even if it’s been a few days. If you were taking Librium for alcohol withdrawal, adding booze back into your life so soon afterwards (or at all) might not be in your best interests. Always check with your doctor first, and stick to the treatment plan you’ve chosen together!

Alcohol Withdrawal and Librium

Alcohol withdrawal can be an incredibly challenging experience, both physically and mentally, for those grappling with dependence. When someone decides to quit drinking after prolonged heavy use, their body and brain often struggle to adjust to the sudden absence of alcohol. Symptoms range from mild anxiety and tremors to severe complications like seizures and hallucinations. 

In medical settings, managing these symptoms effectively is crucial, and Librium is often used to alleviate some of these uncomfortable symptoms. Librium’s calming effects help mitigate the intensity of withdrawal symptoms, providing a safer and more comfortable transition towards sobriety. However, it's important for individuals undergoing alcohol withdrawal to be under medical supervision, as the dosage and duration of Librium treatment need careful monitoring to prevent dependence on this medication.

Mixing Librium and alcohol can be extremely dangerous due to their combined depressant effects on the central nervous system. Both substances slow down brain activity and cause drowsiness, dizziness, impaired coordination, and memory problems. When taken together, they amplify each other's negative impacts. This combination increases the risk of accidents, falls, and other injuries. Moreover, mixing Librium and alcohol can lead to dangerously low blood pressure, slowed breathing, and even coma in severe cases. Additionally, both substances can be habit-forming on their own, and combining them increases the likelihood of developing dependence and addiction.

It is crucial for individuals prescribed Librium to avoid alcohol completely during treatment and to follow their healthcare provider's instructions carefully to ensure safe and effective recovery

Tips To Stay Safe

Finally, here are some tips to stay safe while taking Librium (as well as advice for coping with withdrawal):

  1. Avoid the mix. First and foremost, don’t mix Librium and alcohol — it’s not worth the risk!
  2. Ask for help if you need to. There’s no shame in asking for help — in fact, it’s a sign of strength! If you’re struggling with dependency of any kind, going through withdrawal, or trying to cut back on alcohol and are having trouble, you’re not alone. Many others (such as members of the Reframe community!) have been exactly where you are and are now thriving. Reach out, and we’ll be happy to help! 
  3. Find your people. Once you find people you jibe with — whether it’s online or in person — cultivate those relationships. You’ll need a “tribe” to rely on throughout your journey, and it takes time to really get to know someone. Trust us, it’ll be worth it!
  4. Nourish your body. Whether you’re going through alcohol withdrawal, trying to cut back, or just want to feel your best, nourishing your body is key. Make sure you get plenty of whole grains, healthy fats, and lean proteins in your diet. And load up on those vitamin-rich fruits and veggies! Your body will thank you.
  5. Get moving. Make sure you’re doing some gentle movement every day. Yoga, walking, swimming, dancing in your living room — whatever floats your boat. All of it counts, and all of it will be a step in the right direction, as far as recovery is concerned.
  6. Get rest and take it easy. That closet remodeling project can wait. Make sure you’re getting plenty of rest as your body recovers! Alcohol robs us of much-needed quality sleep, which is essential for restoring health.

And remember, Reframe is here for you as you navigate your relationship with alcohol. Join our thriving community and hear the stories of others who have been exactly where you are and know what it’s like. We wish you the best and are here to support you every step of the way.

Summing Up

All in all, deciding to take a break from booze — especially if Librium is in the picture — might open up exciting new possibilities. Let’s not look at it as deprivation and instead get curious about exploring life beyond booze. There’s so much to discover!

Alcohol and Medications
2024-08-28 9:00
Alcohol and Medications
How Long After Stopping Doxycycline Can I Drink Alcohol?
This is some text inside of a div block.

Alcohol has many interactions with different medications and doxycycline is no exception. Check out our latest blog for more info on how long we should wait to drink safely.

15 min read

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Read Full Article  →

You’ve just finished your dose of doxycycline and are out with friends for dinner. Everyone orders a drink and as you’re about to order a glass of wine, you remember that alcohol and antibiotics shouldn’t be mixed. Although you’re feeling better, you don’t want to compromise the recovery process. But how long you should wait after taking doxycycline before drinking?

Let’s learn how doxycycline works in our body and understand why taking a brief hiatus from alcohol can be a small yet significant step in our quest for safer and more mindful drinking.

Doxycycline: An Infection Destroyer

A glass filled with alcohol alongside various pills placed on a bed

Doxycycline is a medication used to treat bacterial infections in many parts of the body. Known as a tetracycline antibiotic, it kills bacteria or prevents their growth by stopping the production of proteins that bacteria need to survive. Given its anti-inflammatory properties, Doxycycline is often used to treat skin, chest, dental, and some sexually transmitted infections. 

The medication comes in several variations such as a liquid, capsule, tablet, and delayed-relapse tablet. It’s sold under the brand names Vibramycin-D, Efracea, and Periostat. The dosage depends on the reason the medication is prescribed but is typically between 100 mg to 200 mg. Low doses typically used for skin and gum infections aren’t associated with adverse effects. Doxycycline (100 mg) side effects may include diarrhea, vomiting, oral or vaginal thrush, rash, irritation of the esophagus, loss of sense of taste, and ringing in ears. More serious side effects may require emergency medical attention:

  • Severe headache
  • Bruises and bleeding
  • Severe skin reactions
  • Diarrhea 
  • Ringing in the ears 
  • Dizziness
  • Difficulty swallowing
  • Fast heart rate 

Before we discuss specific doxycycline interactions, let’s first understand why alcohol and antibiotics are a dangerous combination.

Can You Drink on Antibiotics?

Drinking while taking any type of antibiotic is not recommended. Some antibiotics, such as metronidazole, tinidazole, griseofulvin, cefoperazone, and more, interact directly with alcohol. Mixing these antibiotics with alcohol can lead to such side effects as a racing heart rate, vomiting, and severe headache.

Even antibiotics without direct interactions can result in increased risks and negative effects when mixed with alcohol. Alcohol impairs our immune function, which is critical in helping us fight against infection and recover quickly. If we’re looking to give our body the best fighting chance to rid us of infections and avoid adverse reactions, drinking while on antibiotics is never a good idea. Let’s further examine how doxycycline and alcohol interact to give us a better idea of how long we should wait to drink.

Specific Interactions Between Doxycycline and Alcohol

Research on the specific ways that alcohol impacts doxycycline is limited, but we do know that mixing alcohol with medications is not recommended since alcohol affects absorption. This means that drinking impacts the effectiveness of doxycycline. 

Alcohol also negatively impacts our immune system, which is critical in fighting infections. It’s a toxin that increases stress in our body and distracts our body from critical functions. Alcohol also kills healthy bacteria that aids in maintaining immune health and can indirectly compromise the effectiveness of the medication, slowing down recovery. 

Although the combination of doxycycline and alcohol aren’t associated with dangerous effects, many of their side effects overlap. This can increase the risk and exacerbate overlapping side effects. Due to the many potential interactions between alcohol and doxycycline, manufacturers recommend choosing an alternative medication if a patient chooses to drink. But what about after completing the medication regimen?

How Long After Stopping Doxycycline Can You Drink?

Doxycycline has an average half-life of 16 to 22 hours. This means that it can take anywhere from 32-44 hours to be eliminated. However, studies show that it can take about five half-lives for a drug to be completely eliminated from our system. To be safe, waiting about five days after stopping doxycycline to drink alcohol is what’s recommended. 

Drinking before the five-day period ends may not present any immediate dangers, as there are no direct interactions between alcohol and doxycycline. However, it can indirectly impact healing and open the door to potential risks. With that in mind, if we’ve accidentally had one drink, should we be worried?

Consequences of Mixing Alcohol and Doxycycline

How Much Alcohol Is Too Much?

When taking doxycycline, alcohol consumption isn’t recommended in any amount. Although mixing doxycycline and alcohol isn’t associated with severely dangerous effects, we all are affected by alcohol and other substances differently. This makes it difficult to determine a “safe” amount of alcohol when taking doxycycline. 

According to the World Health Organization (WHO), no amount of alcohol is safe — with or without doxycycline. If we’re choosing to drink, we should aim to follow moderation consumption guidelines to minimize the risks. We can also consult with our doctor for more individualized recommendations. Even after stopping doxycycline, the drug lingers in our body — opening the door to indirect interactions with alcohol. Let’s get a better picture of the risks.

Negative Effects of Mixing Doxycycline and Alcohol

Even without any direct interactions, mixing doxycycline and alcohol can cause serious effects:

  • Decreased effectiveness. Since alcohol can impact the absorption of doxycycline, the effectiveness of the medication may be compromised. Talk about a waste of time and effort!
  • Gastrointestinal issues. Both alcohol and doxycycline can cause GI issues. When combined, the risk of experiencing GI discomfort is heightened. To prevent discomfort, avoid drinking while on this antibiotic.
  • Liver damage. Our liver breaks down the toxins in our body. This includes the toxic compounds of alcohol and by-products of doxycycline. If we drink while taking the medication, our liver can be overloaded — increasing the risks of liver damage. 
  • Central nervous system (CNS) effects. Alcohol is a CNS depressant, which means it puts a damper on the control system in our brain. This leads to effects such as dizziness, drowsiness, visual disturbances, and more. Many doxycycline side effects overlap with these CNS effects — causing amplified symptoms.   
  • Dehydration. Doxycycline can lead to diarrhea, which promotes excess loss of water. On the other hand, alcohol is a diuretic, which also causes dehydration. When the effects of both are combined, excess dehydration can occur.
  • Kidney damage. Severe dehydration from the diuretic effects of alcohol and the side effects of doxycycline results in higher concentrations of minerals and waste products in our urine. This can cause the formation of crystals that affect proper kidney function. 

As we can see from the long list of negative effects, mixing doxycycline and alcohol can lead to double the trouble. If we’re prescribed doxycycline, how can we navigate drinking safely?

Navigating Doxycycline and Alcohol Safely

Drinking while taking doxycycline and before the five-day elimination period of the medication isn’t recommended. However, if we’re choosing to drink, we can minimize the risks and improve our safety by implementing these mindful drinking practices: 

  • Take medication as prescribed. Following the directions for administering doxycycline can limit adverse effects and ensure its effectiveness. It’s important with antibiotics to complete the entire medication cycle as prescribed. 
  • Avoid drinking. Drinking while taking doxycycline can lead to many adverse effects, despite no indirect interactions. Choose alternatives such as zero-proof alcohol or a creative mocktail
  • Be patient. Waiting until after the five-day period can prevent indirect interactions between alcohol and the lingering medication. After finishing our doxycycline regimen, the last thing we want is to jeopardize our recovery. A little patience can go a long way!
  • Track side effects. Both alcohol and doxycycline cause many side effects. Keeping track can help us identify if adjustments need to be made. 
  • Consult with a physician. This helps us get more individualized healthcare advice. Our doctor is familiar with our health needs and can help us get support and identify other potential interactions.
  • Seek support. If we’re concerned about our alcohol consumption, we can seek support to quit or cut back through different approaches. Try alcohol reduction apps like Reframe, open up to close friends and family, or seek professional treatment programs to learn science-based strategies.
  • Manage immune health. Strengthening our immune system helps us stay healthy and recover quickly. Eat a balanced diet, exercise regularly, and get adequate sleep to boost immune function.

These mindful consumption strategies can apply to doxycycline and, in general, help us develop a more balanced approach to drinking.

The Bottom Line

Understanding the interplay between medications like doxycycline and alcohol is a commitment to better health and mindful living. Although there are no direct interactions between doxycycline and alcohol, the combination can still cause unnecessary risks. We can avoid the adverse effects of mixing alcohol and doxycycline by ensuring that we wait for the five-day elimination window to pass. Whether we're stepping away from doxycycline or simply exploring a more temperate relationship with alcohol, patience, and timing are our trusted allies.

You’ve just finished your dose of doxycycline and are out with friends for dinner. Everyone orders a drink and as you’re about to order a glass of wine, you remember that alcohol and antibiotics shouldn’t be mixed. Although you’re feeling better, you don’t want to compromise the recovery process. But how long you should wait after taking doxycycline before drinking?

Let’s learn how doxycycline works in our body and understand why taking a brief hiatus from alcohol can be a small yet significant step in our quest for safer and more mindful drinking.

Doxycycline: An Infection Destroyer

A glass filled with alcohol alongside various pills placed on a bed

Doxycycline is a medication used to treat bacterial infections in many parts of the body. Known as a tetracycline antibiotic, it kills bacteria or prevents their growth by stopping the production of proteins that bacteria need to survive. Given its anti-inflammatory properties, Doxycycline is often used to treat skin, chest, dental, and some sexually transmitted infections. 

The medication comes in several variations such as a liquid, capsule, tablet, and delayed-relapse tablet. It’s sold under the brand names Vibramycin-D, Efracea, and Periostat. The dosage depends on the reason the medication is prescribed but is typically between 100 mg to 200 mg. Low doses typically used for skin and gum infections aren’t associated with adverse effects. Doxycycline (100 mg) side effects may include diarrhea, vomiting, oral or vaginal thrush, rash, irritation of the esophagus, loss of sense of taste, and ringing in ears. More serious side effects may require emergency medical attention:

  • Severe headache
  • Bruises and bleeding
  • Severe skin reactions
  • Diarrhea 
  • Ringing in the ears 
  • Dizziness
  • Difficulty swallowing
  • Fast heart rate 

Before we discuss specific doxycycline interactions, let’s first understand why alcohol and antibiotics are a dangerous combination.

Can You Drink on Antibiotics?

Drinking while taking any type of antibiotic is not recommended. Some antibiotics, such as metronidazole, tinidazole, griseofulvin, cefoperazone, and more, interact directly with alcohol. Mixing these antibiotics with alcohol can lead to such side effects as a racing heart rate, vomiting, and severe headache.

Even antibiotics without direct interactions can result in increased risks and negative effects when mixed with alcohol. Alcohol impairs our immune function, which is critical in helping us fight against infection and recover quickly. If we’re looking to give our body the best fighting chance to rid us of infections and avoid adverse reactions, drinking while on antibiotics is never a good idea. Let’s further examine how doxycycline and alcohol interact to give us a better idea of how long we should wait to drink.

Specific Interactions Between Doxycycline and Alcohol

Research on the specific ways that alcohol impacts doxycycline is limited, but we do know that mixing alcohol with medications is not recommended since alcohol affects absorption. This means that drinking impacts the effectiveness of doxycycline. 

Alcohol also negatively impacts our immune system, which is critical in fighting infections. It’s a toxin that increases stress in our body and distracts our body from critical functions. Alcohol also kills healthy bacteria that aids in maintaining immune health and can indirectly compromise the effectiveness of the medication, slowing down recovery. 

Although the combination of doxycycline and alcohol aren’t associated with dangerous effects, many of their side effects overlap. This can increase the risk and exacerbate overlapping side effects. Due to the many potential interactions between alcohol and doxycycline, manufacturers recommend choosing an alternative medication if a patient chooses to drink. But what about after completing the medication regimen?

How Long After Stopping Doxycycline Can You Drink?

Doxycycline has an average half-life of 16 to 22 hours. This means that it can take anywhere from 32-44 hours to be eliminated. However, studies show that it can take about five half-lives for a drug to be completely eliminated from our system. To be safe, waiting about five days after stopping doxycycline to drink alcohol is what’s recommended. 

Drinking before the five-day period ends may not present any immediate dangers, as there are no direct interactions between alcohol and doxycycline. However, it can indirectly impact healing and open the door to potential risks. With that in mind, if we’ve accidentally had one drink, should we be worried?

Consequences of Mixing Alcohol and Doxycycline

How Much Alcohol Is Too Much?

When taking doxycycline, alcohol consumption isn’t recommended in any amount. Although mixing doxycycline and alcohol isn’t associated with severely dangerous effects, we all are affected by alcohol and other substances differently. This makes it difficult to determine a “safe” amount of alcohol when taking doxycycline. 

According to the World Health Organization (WHO), no amount of alcohol is safe — with or without doxycycline. If we’re choosing to drink, we should aim to follow moderation consumption guidelines to minimize the risks. We can also consult with our doctor for more individualized recommendations. Even after stopping doxycycline, the drug lingers in our body — opening the door to indirect interactions with alcohol. Let’s get a better picture of the risks.

Negative Effects of Mixing Doxycycline and Alcohol

Even without any direct interactions, mixing doxycycline and alcohol can cause serious effects:

  • Decreased effectiveness. Since alcohol can impact the absorption of doxycycline, the effectiveness of the medication may be compromised. Talk about a waste of time and effort!
  • Gastrointestinal issues. Both alcohol and doxycycline can cause GI issues. When combined, the risk of experiencing GI discomfort is heightened. To prevent discomfort, avoid drinking while on this antibiotic.
  • Liver damage. Our liver breaks down the toxins in our body. This includes the toxic compounds of alcohol and by-products of doxycycline. If we drink while taking the medication, our liver can be overloaded — increasing the risks of liver damage. 
  • Central nervous system (CNS) effects. Alcohol is a CNS depressant, which means it puts a damper on the control system in our brain. This leads to effects such as dizziness, drowsiness, visual disturbances, and more. Many doxycycline side effects overlap with these CNS effects — causing amplified symptoms.   
  • Dehydration. Doxycycline can lead to diarrhea, which promotes excess loss of water. On the other hand, alcohol is a diuretic, which also causes dehydration. When the effects of both are combined, excess dehydration can occur.
  • Kidney damage. Severe dehydration from the diuretic effects of alcohol and the side effects of doxycycline results in higher concentrations of minerals and waste products in our urine. This can cause the formation of crystals that affect proper kidney function. 

As we can see from the long list of negative effects, mixing doxycycline and alcohol can lead to double the trouble. If we’re prescribed doxycycline, how can we navigate drinking safely?

Navigating Doxycycline and Alcohol Safely

Drinking while taking doxycycline and before the five-day elimination period of the medication isn’t recommended. However, if we’re choosing to drink, we can minimize the risks and improve our safety by implementing these mindful drinking practices: 

  • Take medication as prescribed. Following the directions for administering doxycycline can limit adverse effects and ensure its effectiveness. It’s important with antibiotics to complete the entire medication cycle as prescribed. 
  • Avoid drinking. Drinking while taking doxycycline can lead to many adverse effects, despite no indirect interactions. Choose alternatives such as zero-proof alcohol or a creative mocktail
  • Be patient. Waiting until after the five-day period can prevent indirect interactions between alcohol and the lingering medication. After finishing our doxycycline regimen, the last thing we want is to jeopardize our recovery. A little patience can go a long way!
  • Track side effects. Both alcohol and doxycycline cause many side effects. Keeping track can help us identify if adjustments need to be made. 
  • Consult with a physician. This helps us get more individualized healthcare advice. Our doctor is familiar with our health needs and can help us get support and identify other potential interactions.
  • Seek support. If we’re concerned about our alcohol consumption, we can seek support to quit or cut back through different approaches. Try alcohol reduction apps like Reframe, open up to close friends and family, or seek professional treatment programs to learn science-based strategies.
  • Manage immune health. Strengthening our immune system helps us stay healthy and recover quickly. Eat a balanced diet, exercise regularly, and get adequate sleep to boost immune function.

These mindful consumption strategies can apply to doxycycline and, in general, help us develop a more balanced approach to drinking.

The Bottom Line

Understanding the interplay between medications like doxycycline and alcohol is a commitment to better health and mindful living. Although there are no direct interactions between doxycycline and alcohol, the combination can still cause unnecessary risks. We can avoid the adverse effects of mixing alcohol and doxycycline by ensuring that we wait for the five-day elimination window to pass. Whether we're stepping away from doxycycline or simply exploring a more temperate relationship with alcohol, patience, and timing are our trusted allies.

Alcohol and Medications