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Latest Articles
2024-10-10 9:00
Alcohol and Health
Is Alcohol a Macronutrient? How Do You Track It?
This is some text inside of a div block.

Alcohol is its own macronutrient but has no nutritional value. Check out our latest blog for more info on what type of nutrient alcohol is and how to keep track of it.

18 min read

Learn To Track Alcohol Intake With Reframe!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet hundreds of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!

Read Full Article  →

You’re watching an episode of your favorite TV show, Friends, where the gang is gathered at Central Perk. Monica is introducing her latest health-conscious recipe while Joey is just trying to figure out if beer counts as a carb. It’s a humorous moment, but it gets you thinking — how does alcohol fit into your diet?

Alcohol is considered a macronutrient, but it doesn’t fall into the category of carbohydrate, protein, or fat. So, how do we track when we’re counting our “macros” to reach our nutrition goals? Let’s dive into the science behind alcohol and its place in nutrition. Whether you’re a fitness enthusiast or trying to understand more about the effects of alcohol on your health, we’ll help you make sense of it all. 

Understanding Macronutrients

A woman in an orange sweater is holding a calendar

Macronutrients, also commonly referred to as macros, are the building blocks of our nutrition. They are the primary source of energy that we get from food, which includes three main categories: carbohydrates, proteins, and fats. The other main component of our nutrition is micronutrients. Micronutrients are smaller nutritional categories that include vitamins and minerals. Think of the zinc, magnesium, and potassium in a steak rather than the protein, which is the macronutrient. Micronutrients are no less important, but just needed in smaller amounts. 

The three main macronutrients are essential to our nutrition, as they have different functions. A balanced diet consists of all three:

  • Carbohydrates are our main source of energy. 
  • Protein helps build strong bones and muscles.
  • Fats are essential to cell function and protection of our organs. 

A general breakdown of macronutrients in a balanced diet consists of around 20%-35% of calories from fat, 10-35% from protein, and 45%-65% from carbohydrates. Keep in mind, individual dietary requirements may differ, but this is just a general guideline. We can also adjust our macronutrients based on our goals. For example, if we want to build more muscle, we can increase our protein intake. If our goal is weight loss, we can focus on lowering our carbohydrate intake. Keeping track of our macros helps us reach various health goals. But where does alcohol fit in?

Is Alcohol a Macronutrient?

Alcohol is considered the fourth macronutrient since it’s not a protein, carbohydrate, or fat, but still contains calories that the body burns off. But just because macronutrients are the building blocks of our nutrition, doesn’t mean alcohol should be part of our diet. Unlike the other macronutrients, alcohol has no nutritional value and is not essential to our survival. In fact, alcohol is harmful to our health and is associated with long-term conditions that can even be life-threatening.

So, despite the misleading label of alcohol as a nutrient, specifically a macronutrient, alcohol and nutrition don’t go hand in hand. In fact, research shows that high alcohol intake is associated with poor eating habits and differences in body composition. 

Understanding how to properly track alcohol intake is beneficial to our health. But sometimes when we buy alcohol, nutrition labels aren’t on it, and even if they are, they can be misleading. Let’s learn how to properly track our macros when drinking. 

How Do You Track the Macros of Alcohol?

While alcohol is its own macronutrient, it can be counted as a carbohydrate, fat, or a combination of both depending on the type. This is because carbs provide around 4 calories per gram, and fat provides around 9. From an energy lens, alcohol has 7 calories per gram, which sits in between a gram of carbohydrate and fat. While protein also contains 4 calories per gram, nutritionally, alcohol is closer to carbohydrates or fats. 

Determining the carbohydrates or fats in an alcoholic drink is simple when we know the calories. To track alcohol as a carbohydrate, divide the total calories by 4 (since there’s 4 cal/g of carbs). To track it as a fat, divide the calories by 9. To track alcohol as both a carb and fat, split the calories in half and divide one half by 4 and the other by 9.

When we don’t know the calories, that’s when it gets (just slightly) more complicated. Since alcohol is regulated by the Alcohol and Tobacco Tax and Trade Bureau (TTB) rather than the FDA (like other food and drinks), nutritional labeling isn’t required. Luckily, we can use the alcohol by volume — ABV — to calculate the macros. Let’s walk through the steps and look at an example:

There are 28.409 grams in 1 ounce. We can take 28.409 grams and multiply it by the number of ounces of alcohol in our drink to get the number of grams of alcohol. The recommended dietary allowance for protein is 0.8 grams per kilogram of body weight. We then multiply that by 7 calories in a gram (which is how much alcohol has). Multiply that by the alcohol by volume to get total calories, then split it in half and divide one half by 9 and the other by 4 like we mentioned earlier. Here’s the equation for reference:


  • 28.409 g/oz x ___ oz = ___ g
  • ___ g x 0.8g = ___
  • ___ x 7 cal/g = ____ total cal
  • ___ %ABV x ___ total cal = ___ cal per ___ oz
  • Convert calories into macros

To get a better idea of how it works, let’s use 1.5 oz of 40%-ABV vodka as an example:

  • 28.409 g/oz x 1.5 oz = 42.61 g
  • 42.61 g x 0.8g = 34.09 g
  • 34.09 x 7 cal/g = 238.62 total cal
  • 0.04ABV x 238.62 total cal = 96 cal per 1.5 oz
  • 96/4 = 24g of carbs; 96/9 = 10.6g of fat


It may not be practical to whip out an equation each time we drink, but there are plenty of online calculator tools to help us determine the macros in our drink. If you’re in a pinch or there’s no nutrition label, check out our cheat sheet for a guesstimate.

Macronutrients in Common Types of Liquor

Now, why bother doing all this, you may ask? Well, there are benefits to tracking the macronutrients and calories we get from alcohol. Let’s take a look at what those are.

Benefits of Tracking Alcohol and Calories

The fitness industry commonly uses the term “calories in, calories out.” When it comes to weight loss, tracking calories can be effective. But there’s more to the story. Tracking macros helps us reach other health goals and has additional benefits: 

  • Quality over quantity. Not all calories are created equally. When we focus on the macronutrient breakdown, we take into account the quality of our nutrition rather than just the calories. For example, a cup of plain Greek yogurt with granola may have the same number of calories as a Pop-Tart, but the former has a much more balanced breakdown of macros (protein, complex carbs, healthy fats), whereas the Pop-Tart is not a balanced meal and is mostly fat and carbohydrates (not to mention sugar). Tracking the macros and calories in alcohol helps us gain insight into not only how many calories we’re actually consuming, but also where those calories are coming from.



    Tip: Check out Reframe’s handy alcohol calorie calculator to easily track how many calories you’re getting from alcohol.
  • A tool for different health goals. Whether we’re looking to build muscle, improve our metabolism, lose weight, or ensure we’re eating a balanced diet, counting macros can help us reach certain health goals. 
  • Less restriction. Tracking macros can be less restrictive for some of us. It doesn’t restrict certain food groups like some diets and helps promote the message that all foods can fit into a healthy diet. Since alcohol has calories, it’s important to account for it when tracking macros and calories. 
  • Greater insight. Tracking our macros, like tracking our alcohol intake, gives us greater insight into how our diet affects us. This helps us adjust our nutrition and use it to boost our overall well-being.

Understanding the benefits of tracking macros can influence our choices. Let’s dive into some drink options that may be more aligned with our goals. 

Macro-Friendly Drink Options

At the end of the day, all alcohol is empty calories, but if we do decide to have a drink, we can be mindful of our nutrition by going for more macro-friendly options. Keep these tips in mind the next time you’re choosing a drink:

  • Opt for lower alcohol content. The higher the alcohol content, the more calories a drink has. Go for lower alcohol options such as beer or hard seltzers rather than liquor.
  • Use no/low cal mixers. Mixers such as artificial fruit juices, soda, and syrups can add to the calories in alcohol. Opt for no or low-calorie options such as sparkling water or tomato juice.
  • Go for light beers. Light beers often use fewer grains and additives such as corn or rice to lower the alcohol content and calories.
  • Ask for “skinny” versions of cocktails. A “skinny” version of a cocktail is a lower-sugar or lower-calorie version. The sugar can be replaced with Stevia, sugary mixers may be replaced with soda water, or the alcohol can be replaced with lower-alcohol spirits.
  • Try low-calorie wines. Like light beers, low-calorie wines are made using modifications of the ingredients and fermentation process. The lower sugar and alcohol levels leads to a more macro-friendly wine.

Now that we’re equipped with macro-friendly drink options, let’s explore some practical tips to further manage our alcohol intake and nutrition. 

Tips for Managing Alcohol and Nutrition

Our health consists of many aspects, and what we consume is among the most important. Managing our nutrition and alcohol intake using these tips helps us work towards a healthier lifestyle:

  • Keep track. Tracking, whether it’s our macros for nutrition or our alcohol intake, helps us get a clearer picture of our habits. By gathering this important information, we can develop goals to improve our overall health and well-being.
  • Be intentional. Choose more nutrient-dense dietary options such as whole foods and lots of veggies (with an occasional treat here and there for balance!). When it comes to drinking, set limits, choose low-alcohol options, or better yet, opt for alcohol-free alternatives
  • Avoid empty calories. Empty calories have no nutritional value and increase the chances of weight gain. Quitting or cutting back on alcohol reduces intake of these empty calories. 
  • Stay active. Participating in daily movement has benefits to our physical health, such as improving cardiovascular health and preventing excess fat. It also has positive effects on our mental health such as increasing our confidence and boosting our mood.
  • Develop a support system. Having others we can rely on is important for our mental and social health. Especially during challenging times such as developing a healthier relationship with alcohol or managing our nutrition, social support can serve as motivation and encourage us to continue striving for better. 

Managing our nutrition through tracking alcohol intake is the first step to a healthier lifestyle. We can continue to set ourselves up for success by developing positive skills such as mindfulness, coping mechanisms, and gratitude.

Sipping Wisely

As we can see, understanding where alcohol fits into our nutrition goals isn’t just for fitness enthusiasts. It’s valuable for any one of us looking to make more informed choices. Whether we’re looking to quit or cut back on alcohol or simply aiming to have a more balanced diet, knowing how to track alcohol as part of our macros is a game-changer. So, the next time we’re enjoying a drink, we’ll know exactly how it fits into our plan, making our journey to a healthier, happier lifestyle more manageable. Cheers to more informed choices!

You’re watching an episode of your favorite TV show, Friends, where the gang is gathered at Central Perk. Monica is introducing her latest health-conscious recipe while Joey is just trying to figure out if beer counts as a carb. It’s a humorous moment, but it gets you thinking — how does alcohol fit into your diet?

Alcohol is considered a macronutrient, but it doesn’t fall into the category of carbohydrate, protein, or fat. So, how do we track when we’re counting our “macros” to reach our nutrition goals? Let’s dive into the science behind alcohol and its place in nutrition. Whether you’re a fitness enthusiast or trying to understand more about the effects of alcohol on your health, we’ll help you make sense of it all. 

Understanding Macronutrients

A woman in an orange sweater is holding a calendar

Macronutrients, also commonly referred to as macros, are the building blocks of our nutrition. They are the primary source of energy that we get from food, which includes three main categories: carbohydrates, proteins, and fats. The other main component of our nutrition is micronutrients. Micronutrients are smaller nutritional categories that include vitamins and minerals. Think of the zinc, magnesium, and potassium in a steak rather than the protein, which is the macronutrient. Micronutrients are no less important, but just needed in smaller amounts. 

The three main macronutrients are essential to our nutrition, as they have different functions. A balanced diet consists of all three:

  • Carbohydrates are our main source of energy. 
  • Protein helps build strong bones and muscles.
  • Fats are essential to cell function and protection of our organs. 

A general breakdown of macronutrients in a balanced diet consists of around 20%-35% of calories from fat, 10-35% from protein, and 45%-65% from carbohydrates. Keep in mind, individual dietary requirements may differ, but this is just a general guideline. We can also adjust our macronutrients based on our goals. For example, if we want to build more muscle, we can increase our protein intake. If our goal is weight loss, we can focus on lowering our carbohydrate intake. Keeping track of our macros helps us reach various health goals. But where does alcohol fit in?

Is Alcohol a Macronutrient?

Alcohol is considered the fourth macronutrient since it’s not a protein, carbohydrate, or fat, but still contains calories that the body burns off. But just because macronutrients are the building blocks of our nutrition, doesn’t mean alcohol should be part of our diet. Unlike the other macronutrients, alcohol has no nutritional value and is not essential to our survival. In fact, alcohol is harmful to our health and is associated with long-term conditions that can even be life-threatening.

So, despite the misleading label of alcohol as a nutrient, specifically a macronutrient, alcohol and nutrition don’t go hand in hand. In fact, research shows that high alcohol intake is associated with poor eating habits and differences in body composition. 

Understanding how to properly track alcohol intake is beneficial to our health. But sometimes when we buy alcohol, nutrition labels aren’t on it, and even if they are, they can be misleading. Let’s learn how to properly track our macros when drinking. 

How Do You Track the Macros of Alcohol?

While alcohol is its own macronutrient, it can be counted as a carbohydrate, fat, or a combination of both depending on the type. This is because carbs provide around 4 calories per gram, and fat provides around 9. From an energy lens, alcohol has 7 calories per gram, which sits in between a gram of carbohydrate and fat. While protein also contains 4 calories per gram, nutritionally, alcohol is closer to carbohydrates or fats. 

Determining the carbohydrates or fats in an alcoholic drink is simple when we know the calories. To track alcohol as a carbohydrate, divide the total calories by 4 (since there’s 4 cal/g of carbs). To track it as a fat, divide the calories by 9. To track alcohol as both a carb and fat, split the calories in half and divide one half by 4 and the other by 9.

When we don’t know the calories, that’s when it gets (just slightly) more complicated. Since alcohol is regulated by the Alcohol and Tobacco Tax and Trade Bureau (TTB) rather than the FDA (like other food and drinks), nutritional labeling isn’t required. Luckily, we can use the alcohol by volume — ABV — to calculate the macros. Let’s walk through the steps and look at an example:

There are 28.409 grams in 1 ounce. We can take 28.409 grams and multiply it by the number of ounces of alcohol in our drink to get the number of grams of alcohol. The recommended dietary allowance for protein is 0.8 grams per kilogram of body weight. We then multiply that by 7 calories in a gram (which is how much alcohol has). Multiply that by the alcohol by volume to get total calories, then split it in half and divide one half by 9 and the other by 4 like we mentioned earlier. Here’s the equation for reference:


  • 28.409 g/oz x ___ oz = ___ g
  • ___ g x 0.8g = ___
  • ___ x 7 cal/g = ____ total cal
  • ___ %ABV x ___ total cal = ___ cal per ___ oz
  • Convert calories into macros

To get a better idea of how it works, let’s use 1.5 oz of 40%-ABV vodka as an example:

  • 28.409 g/oz x 1.5 oz = 42.61 g
  • 42.61 g x 0.8g = 34.09 g
  • 34.09 x 7 cal/g = 238.62 total cal
  • 0.04ABV x 238.62 total cal = 96 cal per 1.5 oz
  • 96/4 = 24g of carbs; 96/9 = 10.6g of fat


It may not be practical to whip out an equation each time we drink, but there are plenty of online calculator tools to help us determine the macros in our drink. If you’re in a pinch or there’s no nutrition label, check out our cheat sheet for a guesstimate.

Macronutrients in Common Types of Liquor

Now, why bother doing all this, you may ask? Well, there are benefits to tracking the macronutrients and calories we get from alcohol. Let’s take a look at what those are.

Benefits of Tracking Alcohol and Calories

The fitness industry commonly uses the term “calories in, calories out.” When it comes to weight loss, tracking calories can be effective. But there’s more to the story. Tracking macros helps us reach other health goals and has additional benefits: 

  • Quality over quantity. Not all calories are created equally. When we focus on the macronutrient breakdown, we take into account the quality of our nutrition rather than just the calories. For example, a cup of plain Greek yogurt with granola may have the same number of calories as a Pop-Tart, but the former has a much more balanced breakdown of macros (protein, complex carbs, healthy fats), whereas the Pop-Tart is not a balanced meal and is mostly fat and carbohydrates (not to mention sugar). Tracking the macros and calories in alcohol helps us gain insight into not only how many calories we’re actually consuming, but also where those calories are coming from.



    Tip: Check out Reframe’s handy alcohol calorie calculator to easily track how many calories you’re getting from alcohol.
  • A tool for different health goals. Whether we’re looking to build muscle, improve our metabolism, lose weight, or ensure we’re eating a balanced diet, counting macros can help us reach certain health goals. 
  • Less restriction. Tracking macros can be less restrictive for some of us. It doesn’t restrict certain food groups like some diets and helps promote the message that all foods can fit into a healthy diet. Since alcohol has calories, it’s important to account for it when tracking macros and calories. 
  • Greater insight. Tracking our macros, like tracking our alcohol intake, gives us greater insight into how our diet affects us. This helps us adjust our nutrition and use it to boost our overall well-being.

Understanding the benefits of tracking macros can influence our choices. Let’s dive into some drink options that may be more aligned with our goals. 

Macro-Friendly Drink Options

At the end of the day, all alcohol is empty calories, but if we do decide to have a drink, we can be mindful of our nutrition by going for more macro-friendly options. Keep these tips in mind the next time you’re choosing a drink:

  • Opt for lower alcohol content. The higher the alcohol content, the more calories a drink has. Go for lower alcohol options such as beer or hard seltzers rather than liquor.
  • Use no/low cal mixers. Mixers such as artificial fruit juices, soda, and syrups can add to the calories in alcohol. Opt for no or low-calorie options such as sparkling water or tomato juice.
  • Go for light beers. Light beers often use fewer grains and additives such as corn or rice to lower the alcohol content and calories.
  • Ask for “skinny” versions of cocktails. A “skinny” version of a cocktail is a lower-sugar or lower-calorie version. The sugar can be replaced with Stevia, sugary mixers may be replaced with soda water, or the alcohol can be replaced with lower-alcohol spirits.
  • Try low-calorie wines. Like light beers, low-calorie wines are made using modifications of the ingredients and fermentation process. The lower sugar and alcohol levels leads to a more macro-friendly wine.

Now that we’re equipped with macro-friendly drink options, let’s explore some practical tips to further manage our alcohol intake and nutrition. 

Tips for Managing Alcohol and Nutrition

Our health consists of many aspects, and what we consume is among the most important. Managing our nutrition and alcohol intake using these tips helps us work towards a healthier lifestyle:

  • Keep track. Tracking, whether it’s our macros for nutrition or our alcohol intake, helps us get a clearer picture of our habits. By gathering this important information, we can develop goals to improve our overall health and well-being.
  • Be intentional. Choose more nutrient-dense dietary options such as whole foods and lots of veggies (with an occasional treat here and there for balance!). When it comes to drinking, set limits, choose low-alcohol options, or better yet, opt for alcohol-free alternatives
  • Avoid empty calories. Empty calories have no nutritional value and increase the chances of weight gain. Quitting or cutting back on alcohol reduces intake of these empty calories. 
  • Stay active. Participating in daily movement has benefits to our physical health, such as improving cardiovascular health and preventing excess fat. It also has positive effects on our mental health such as increasing our confidence and boosting our mood.
  • Develop a support system. Having others we can rely on is important for our mental and social health. Especially during challenging times such as developing a healthier relationship with alcohol or managing our nutrition, social support can serve as motivation and encourage us to continue striving for better. 

Managing our nutrition through tracking alcohol intake is the first step to a healthier lifestyle. We can continue to set ourselves up for success by developing positive skills such as mindfulness, coping mechanisms, and gratitude.

Sipping Wisely

As we can see, understanding where alcohol fits into our nutrition goals isn’t just for fitness enthusiasts. It’s valuable for any one of us looking to make more informed choices. Whether we’re looking to quit or cut back on alcohol or simply aiming to have a more balanced diet, knowing how to track alcohol as part of our macros is a game-changer. So, the next time we’re enjoying a drink, we’ll know exactly how it fits into our plan, making our journey to a healthier, happier lifestyle more manageable. Cheers to more informed choices!

Alcohol and Health
2024-10-08 9:00
Alcohol and Health
What Is Zieve's Syndrome?
This is some text inside of a div block.

Zieve’s syndrome is a rare condition, but can undoubtedly affect those who drink heavily. Check out our latest blog for more info on how this triple threat is linked to alcohol.

17 min read

Care for Your Liver Health With Reframe!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet hundreds of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!

Read Full Article  →

You wake up groggy one morning after yet another big night out. But today, it’s not just the usual headache and nausea that accompanies a night of heavy drinking. As you drag yourself to the bathroom to freshen up, you feel a pang in your stomach. When you catch your reflection in the mirror, you do a double take. Your skin and the whites of your eyes have taken on a yellowish hue as if there’s a filter on the image staring back at you. Confused and alarmed, you wonder, “What’s happening to me?”

Two individuals seated at a table, each with a beer bottle

Excessive drinking for an extended period of time doesn’t come without consequence. Meet Zieve’s syndrome, an often overlooked condition that occurs in those of us with a history of heavy drinking. Unlike typical liver disease, Zieve’s syndrome combines multiple complications, making it a unique and challenging condition to understand and manage. Let’s further explore what Zieve’s syndrome is to learn what we can do to prevent or address it. 

Understanding Zieve’s Syndrome: An Underreported Cause of Alcohol-Induced Anemia 

Zieve’s syndrome is a complication of alcohol-related liver injury that stems from excessive drinking. It was first described by Dr. Leslie Zieve in 1957 when he noticed that many patients with alcohol-related liver injury shared three common issues. The three signs of Zieve’s syndrome are yellowing of the skin and eyes (jaundice), abnormal breakdown of red blood cells (hemolytic anemia), and high levels of lipids such as cholesterol and triglycerides in the blood (hyperlipidemia). This trio causes a range of symptoms associated with Zieve’s syndrome.

Jaundice is one of the big three signs. We can identify jaundice in four ways:

  • Yellowing of skin, eyes, and other mucous membranes
  • Dark-colored urine
  • Pale stools
  • Itchy skin

Anemia is a condition that occurs when our blood doesn’t have enough healthy red blood cells or proteins (hemoglobin), which carry oxygen to the rest of the body. If our body doesn’t get enough oxygen, we may experience a range of symptoms: 

  • Weakness
  • Dizziness
  • Confusion 
  • Pale skin
  • Increased heart rate
  • Fever

Hyperlipidemia (or high levels of fat particles in the blood) isn’t associated with any specific symptoms. But when this condition combines with jaundice and anemia, the result may be:

  • Abdominal pain
  • Nausea
  • Vomiting
  • Fatigue
  • Low-grade fever 

Now that we understand what to look out for, let’s get to know why Zieve’s syndrome occurs.

What Causes Zieve’s Syndrome?

Zieve’s syndrome occurs due to liver injury from excessive drinking. Since our liver is the main organ that breaks down alcohol, it’s consistently exposed to toxins that destroy its cells. Over time, damage to our liver cells leads to inflammation, scarring, and liver dysfunction. While our liver is in charge of breaking down toxins, it also plays a key role in regulating the lipids in our blood. When our liver isn’t functioning properly, fat builds up, leading to hyperlipidemia. Our liver also struggles to remove bilirubin, a yellowing pigment that is a waste product of our blood, leading to jaundice. 

Jaundice can also be caused by hemolytic anemia, another component of Zieve’s syndrome. Hemolytic anemia is a disorder where red blood cells are destroyed faster than they can be produced. While we know hemolytic anemia in Zieve’s syndrome can contribute to jaundice, the cause of hemolytic anemia isn’t completely understood. 

Researchers believe that Zieve’s syndrome can be a combination of several different factors. First, elevated levels of lipids in our body can disrupt the red blood cell membrane and cause it to break down (hemolysis). Additionally, vitamin E, which plays a vital role in red blood cell metabolism, can be depleted by alcohol, contributing to hemolysis. Lastly, acetaldehyde, the toxic compound in alcohol, impairs red blood cell enzymes, which can make red blood cells more susceptible to injury. While it seems like Zieve’s syndrome can be caused by many different elements, the underlying factor is alcohol-related liver injury. In short, damage to our liver from excessive drinking can lead to Zieve’s syndrome. To fully grasp who is most vulnerable, let’s delve into the specific risk factors that increase the likelihood of its onset. 

Zieve’s Syndrome Risk Factors 

As we’ve learned, Zieve’s syndrome occurs due to alcohol-related liver damage, and the risk factor for alcohol-related liver damage is excessive drinking. According to the CDC, excessive drinking is outlined by the following criteria:

  • 14 standard drinks per week for men
  • 7 standard drinks per week for women 
  • 4 drinks in one sitting for men
  • 3 drinks in one sitting for women 

One standard drink refers to 14 grams of pure alcohol. This looks different depending on the type of alcoholic beverage. For example,14 grams of pure alcohol is found in roughly 12 oz of 5% beer or 1.5 oz of distilled spirits. When evaluating our drinking habits, it’s important to ensure we’re using standard drink measurements, as one drink we order at the bar can easily be two or three standard drinks. 

To understand the direct link between excessive drinking and liver damage, let’s take a look at some sobering facts. Research on alcoholic liver disease published by the National Library of Medicine outlines the following findings:

  • Consumption of 30-50 grams of alcohol per day or about 2-4 standard drinks a day for 5 years can lead to alcohol-related liver disease.
  • Cirrhosis or permanent liver scarring occurs in 30% of those with a history of heavy drinking (40 grams per day).
  • Steatosis (fatty liver disease) occurs in 90% of those who drink more than 60 grams of alcohol per day.
  • Quantity and duration of alcohol consumption are the highest risk factors for the development of liver disease.

Zieve’s syndrome, which is caused by alcohol-related liver damage, shares the same risk factors and helps us understand why it develops. While excessive drinking is the primary risk factor for Zieve’s syndrome, treating it isn’t as simple as not drinking excessively. 

Tips for Preventing Zieve’s Syndrome

Treatment for Zieve’s Syndrome

A core component of treating Zieve’s syndrome is avoiding alcohol. Research shows that patients with Zieve’s syndrome can recover 4 to 6 weeks after abstinence from alcohol. Continuing to drink, even below the criteria for excessive drinking, can lead to severe liver damage and cirrhosis. Cirrhosis is permanent liver scarring that leads to liver failure. Oftentimes, the only treatment for chronic liver failure is a liver transplant.

Aside from lifestyle changes, the other main treatments for Zieve’s syndrome are blood transfusions. Normal blood transfusions can increase our red blood cell count, combating jaundice and anemia. Plasmapheresis helps treat hyperlipidemia by removing the triglycerides (fatty acids) from the plasma in our blood. Together, these treatments address each component of Zieve’s syndrome and help us improve our liver health. By prioritizing liver health, we can more effectively prevent Zieve’s syndrome. Let’s talk strategy. 

Tips for Preventing Zieve’s Syndrome

Although Zieve’s syndrome manifests through a triad of conditions (and even more symptoms), preventing it is much less complicated. It’s centered around mindful drinking, which we can practice in the following ways: 

  • Set limits. Follow moderation guidelines or track your consumption, then develop attainable goals to cut back. 
  • Choose alternatives. Better yet, choose alcohol-free alternatives to avoid alcohol altogether. Since alcohol is toxic to our liver, avoiding alcohol is beneficial for it. 
  • Manage liver health. Aside from eliminating toxic substances like alcohol, eating a liver-healthy diet, getting adequate sleep, and participating in daily exercise help improve the function of our liver (more on this in the next section).
  • Catch it early. This goes for both negative drinking habits and alcohol-related liver damage. Early intervention helps prevent further damage from alcohol. Look out for early signs of alcohol misuse to stop it in its tracks to help prevent adverse health effects such as liver damage.
  • Get support for quitting or cutting back. The way alcohol hijacks our brain’s reward system can make quitting or cutting back not always as easy as it sounds. Luckily, we have a range of support options to explore including behavioral treatments, psychological therapy, and support groups like the Reframe community.

Improving and maintaining the health of our liver is a crucial aspect of preventing and treating Zieve’s syndrome. Let’s dive into more detail on ways we can boost the well-being of our liver.

Leveling Up Your Liver

To level up our health, it’s crucial to not only prevent conditions like Zieve’s syndrome, but also to enhance our liver function. The liver is in charge of many major functions in our body including detoxification, supporting metabolism, and more. We can prioritize our liver health by implementing these strategies:

  • Steer clear of toxins. In addition to alcohol, pesticides and other toxins can damage our liver. Take care when washing produce and read warning labels on chemicals before use. 
  • Check your supplements. Research shows that some herbal and dietary supplements account for 20% of liver injury in the US. Be sure to check if the supplements you’re taking are on the National Institutes of Health database of toxic substances or consult with your doctor for individual medical advice. 
  • Maintain a healthy weight. Having a sustainable exercise routine helps us stay active and avoid excess fat buildup in our liver which can lead to dysfunction. Find enjoyable ways to move your body such as going for a hike or taking a dance or exercise class. Eating a balanced diet can also help us maintain a healthy weight and liver. The American Liver Foundation recommends avoiding foods high in fat, sugar, and salt. 
  • Use medications properly. Taking too much or taking them for extended periods of time can be harmful to our liver. Make sure to follow directions for all prescribed medications. 
  • Prevent hepatitis A, B, and C. Hepatitis A and B are viral diseases and can be prevented through vaccinations. While the vaccinations are now recommended for children, some adults have not gotten them. Talk to your doctor to see if it’s recommended. For hepatitis C, there’s no vaccination. This virus is spread through blood and can lead to permanent liver damage if left untreated. Practice safe use and disposal of needles and look out for signs of hepatitis C including stomach pain, joint pain, dry mouth, fatigue, loss of appetite, and yellowing of the skin or eyes (jaundice).

Taking care of our liver health ultimately improves our overall health and well-being. 

From Awareness to Action

Zieve’s syndrome is a complication of alcohol-related liver damage that leads to a treacherous trio of jaundice, anemia, and hyperlipidemia. Now that we understand how it works and what causes it, we can better treat and prevent it by prioritizing our liver health! Quit or cut back on alcohol, load up liver-friendly foods, and steer clear of toxins to give your liver a reprieve and avoid Zieve’s!

You wake up groggy one morning after yet another big night out. But today, it’s not just the usual headache and nausea that accompanies a night of heavy drinking. As you drag yourself to the bathroom to freshen up, you feel a pang in your stomach. When you catch your reflection in the mirror, you do a double take. Your skin and the whites of your eyes have taken on a yellowish hue as if there’s a filter on the image staring back at you. Confused and alarmed, you wonder, “What’s happening to me?”

Two individuals seated at a table, each with a beer bottle

Excessive drinking for an extended period of time doesn’t come without consequence. Meet Zieve’s syndrome, an often overlooked condition that occurs in those of us with a history of heavy drinking. Unlike typical liver disease, Zieve’s syndrome combines multiple complications, making it a unique and challenging condition to understand and manage. Let’s further explore what Zieve’s syndrome is to learn what we can do to prevent or address it. 

Understanding Zieve’s Syndrome: An Underreported Cause of Alcohol-Induced Anemia 

Zieve’s syndrome is a complication of alcohol-related liver injury that stems from excessive drinking. It was first described by Dr. Leslie Zieve in 1957 when he noticed that many patients with alcohol-related liver injury shared three common issues. The three signs of Zieve’s syndrome are yellowing of the skin and eyes (jaundice), abnormal breakdown of red blood cells (hemolytic anemia), and high levels of lipids such as cholesterol and triglycerides in the blood (hyperlipidemia). This trio causes a range of symptoms associated with Zieve’s syndrome.

Jaundice is one of the big three signs. We can identify jaundice in four ways:

  • Yellowing of skin, eyes, and other mucous membranes
  • Dark-colored urine
  • Pale stools
  • Itchy skin

Anemia is a condition that occurs when our blood doesn’t have enough healthy red blood cells or proteins (hemoglobin), which carry oxygen to the rest of the body. If our body doesn’t get enough oxygen, we may experience a range of symptoms: 

  • Weakness
  • Dizziness
  • Confusion 
  • Pale skin
  • Increased heart rate
  • Fever

Hyperlipidemia (or high levels of fat particles in the blood) isn’t associated with any specific symptoms. But when this condition combines with jaundice and anemia, the result may be:

  • Abdominal pain
  • Nausea
  • Vomiting
  • Fatigue
  • Low-grade fever 

Now that we understand what to look out for, let’s get to know why Zieve’s syndrome occurs.

What Causes Zieve’s Syndrome?

Zieve’s syndrome occurs due to liver injury from excessive drinking. Since our liver is the main organ that breaks down alcohol, it’s consistently exposed to toxins that destroy its cells. Over time, damage to our liver cells leads to inflammation, scarring, and liver dysfunction. While our liver is in charge of breaking down toxins, it also plays a key role in regulating the lipids in our blood. When our liver isn’t functioning properly, fat builds up, leading to hyperlipidemia. Our liver also struggles to remove bilirubin, a yellowing pigment that is a waste product of our blood, leading to jaundice. 

Jaundice can also be caused by hemolytic anemia, another component of Zieve’s syndrome. Hemolytic anemia is a disorder where red blood cells are destroyed faster than they can be produced. While we know hemolytic anemia in Zieve’s syndrome can contribute to jaundice, the cause of hemolytic anemia isn’t completely understood. 

Researchers believe that Zieve’s syndrome can be a combination of several different factors. First, elevated levels of lipids in our body can disrupt the red blood cell membrane and cause it to break down (hemolysis). Additionally, vitamin E, which plays a vital role in red blood cell metabolism, can be depleted by alcohol, contributing to hemolysis. Lastly, acetaldehyde, the toxic compound in alcohol, impairs red blood cell enzymes, which can make red blood cells more susceptible to injury. While it seems like Zieve’s syndrome can be caused by many different elements, the underlying factor is alcohol-related liver injury. In short, damage to our liver from excessive drinking can lead to Zieve’s syndrome. To fully grasp who is most vulnerable, let’s delve into the specific risk factors that increase the likelihood of its onset. 

Zieve’s Syndrome Risk Factors 

As we’ve learned, Zieve’s syndrome occurs due to alcohol-related liver damage, and the risk factor for alcohol-related liver damage is excessive drinking. According to the CDC, excessive drinking is outlined by the following criteria:

  • 14 standard drinks per week for men
  • 7 standard drinks per week for women 
  • 4 drinks in one sitting for men
  • 3 drinks in one sitting for women 

One standard drink refers to 14 grams of pure alcohol. This looks different depending on the type of alcoholic beverage. For example,14 grams of pure alcohol is found in roughly 12 oz of 5% beer or 1.5 oz of distilled spirits. When evaluating our drinking habits, it’s important to ensure we’re using standard drink measurements, as one drink we order at the bar can easily be two or three standard drinks. 

To understand the direct link between excessive drinking and liver damage, let’s take a look at some sobering facts. Research on alcoholic liver disease published by the National Library of Medicine outlines the following findings:

  • Consumption of 30-50 grams of alcohol per day or about 2-4 standard drinks a day for 5 years can lead to alcohol-related liver disease.
  • Cirrhosis or permanent liver scarring occurs in 30% of those with a history of heavy drinking (40 grams per day).
  • Steatosis (fatty liver disease) occurs in 90% of those who drink more than 60 grams of alcohol per day.
  • Quantity and duration of alcohol consumption are the highest risk factors for the development of liver disease.

Zieve’s syndrome, which is caused by alcohol-related liver damage, shares the same risk factors and helps us understand why it develops. While excessive drinking is the primary risk factor for Zieve’s syndrome, treating it isn’t as simple as not drinking excessively. 

Tips for Preventing Zieve’s Syndrome

Treatment for Zieve’s Syndrome

A core component of treating Zieve’s syndrome is avoiding alcohol. Research shows that patients with Zieve’s syndrome can recover 4 to 6 weeks after abstinence from alcohol. Continuing to drink, even below the criteria for excessive drinking, can lead to severe liver damage and cirrhosis. Cirrhosis is permanent liver scarring that leads to liver failure. Oftentimes, the only treatment for chronic liver failure is a liver transplant.

Aside from lifestyle changes, the other main treatments for Zieve’s syndrome are blood transfusions. Normal blood transfusions can increase our red blood cell count, combating jaundice and anemia. Plasmapheresis helps treat hyperlipidemia by removing the triglycerides (fatty acids) from the plasma in our blood. Together, these treatments address each component of Zieve’s syndrome and help us improve our liver health. By prioritizing liver health, we can more effectively prevent Zieve’s syndrome. Let’s talk strategy. 

Tips for Preventing Zieve’s Syndrome

Although Zieve’s syndrome manifests through a triad of conditions (and even more symptoms), preventing it is much less complicated. It’s centered around mindful drinking, which we can practice in the following ways: 

  • Set limits. Follow moderation guidelines or track your consumption, then develop attainable goals to cut back. 
  • Choose alternatives. Better yet, choose alcohol-free alternatives to avoid alcohol altogether. Since alcohol is toxic to our liver, avoiding alcohol is beneficial for it. 
  • Manage liver health. Aside from eliminating toxic substances like alcohol, eating a liver-healthy diet, getting adequate sleep, and participating in daily exercise help improve the function of our liver (more on this in the next section).
  • Catch it early. This goes for both negative drinking habits and alcohol-related liver damage. Early intervention helps prevent further damage from alcohol. Look out for early signs of alcohol misuse to stop it in its tracks to help prevent adverse health effects such as liver damage.
  • Get support for quitting or cutting back. The way alcohol hijacks our brain’s reward system can make quitting or cutting back not always as easy as it sounds. Luckily, we have a range of support options to explore including behavioral treatments, psychological therapy, and support groups like the Reframe community.

Improving and maintaining the health of our liver is a crucial aspect of preventing and treating Zieve’s syndrome. Let’s dive into more detail on ways we can boost the well-being of our liver.

Leveling Up Your Liver

To level up our health, it’s crucial to not only prevent conditions like Zieve’s syndrome, but also to enhance our liver function. The liver is in charge of many major functions in our body including detoxification, supporting metabolism, and more. We can prioritize our liver health by implementing these strategies:

  • Steer clear of toxins. In addition to alcohol, pesticides and other toxins can damage our liver. Take care when washing produce and read warning labels on chemicals before use. 
  • Check your supplements. Research shows that some herbal and dietary supplements account for 20% of liver injury in the US. Be sure to check if the supplements you’re taking are on the National Institutes of Health database of toxic substances or consult with your doctor for individual medical advice. 
  • Maintain a healthy weight. Having a sustainable exercise routine helps us stay active and avoid excess fat buildup in our liver which can lead to dysfunction. Find enjoyable ways to move your body such as going for a hike or taking a dance or exercise class. Eating a balanced diet can also help us maintain a healthy weight and liver. The American Liver Foundation recommends avoiding foods high in fat, sugar, and salt. 
  • Use medications properly. Taking too much or taking them for extended periods of time can be harmful to our liver. Make sure to follow directions for all prescribed medications. 
  • Prevent hepatitis A, B, and C. Hepatitis A and B are viral diseases and can be prevented through vaccinations. While the vaccinations are now recommended for children, some adults have not gotten them. Talk to your doctor to see if it’s recommended. For hepatitis C, there’s no vaccination. This virus is spread through blood and can lead to permanent liver damage if left untreated. Practice safe use and disposal of needles and look out for signs of hepatitis C including stomach pain, joint pain, dry mouth, fatigue, loss of appetite, and yellowing of the skin or eyes (jaundice).

Taking care of our liver health ultimately improves our overall health and well-being. 

From Awareness to Action

Zieve’s syndrome is a complication of alcohol-related liver damage that leads to a treacherous trio of jaundice, anemia, and hyperlipidemia. Now that we understand how it works and what causes it, we can better treat and prevent it by prioritizing our liver health! Quit or cut back on alcohol, load up liver-friendly foods, and steer clear of toxins to give your liver a reprieve and avoid Zieve’s!

Alcohol and Health
2024-10-08 9:00
Alcohol and Health
Alcohol’s Effects on Your Bowel Movements
This is some text inside of a div block.

From loose stools to more frequent trips to the restroom, day-after-drinking poops can be unpleasant. Check out our latest blog for more info on how alcohol affects our bowel movements.

17 min read

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Read Full Article  →

You’re enjoying a night out with friends, cocktail in hand when suddenly the joy of the evening takes a sharp turn. You find yourself sprinting to the bathroom. Sound familiar? Alcohol can make us feel good in the moment, but it often leaves our digestive system in a state of turmoil. 

Let’s follow alcohol’s journey through our digestive system from the second it touches our lips through the egress of our intestines, which sometimes ends in an expedited or delayed release. Whether we’re looking to avoid the dreaded “alcohol poops” or aiming to improve our gut health, understanding how alcohol affects our digestive system can help keep our bathroom sprints at bay. Let’s dive into a less talked about side of alcohol — its effects on our bowel movements.

Understanding the Interaction: Alcohol Metabolism and Your Digestive System

A man holding his stomach

Alcohol, unlike the food and drinks we consume, is absorbed in the bloodstream, causing intoxication when our blood alcohol concentration rises. Although it’s absorbed into our bloodstream, each part of the digestive process is still involved in absorbing, processing, and breaking down alcohol (metabolization). Let’s follow the path of the digestive process to see how alcohol affects each stage.

1. Mouth and Throat

Although we associate our stomach and intestines with digestion, the process begins as soon as food or drink enters our mouth. When we drink alcohol, small amounts are absorbed through the lining of our mouth and throat. 

As the rest travels through the rest of the digestive tract, the alcohol that is absorbed into the blood begins to break down into a toxic compound known as acetaldehyde. 

Since alcohol is absorbed into our bloodstream, acetaldehyde not only damages our cells within our digestive system but also other parts of our body — explaining the many health conditions associated with drinking. But this is just the first step — let’s keep going!

2. Esophagus

The esophagus is like a muscular tube that connects our throat to our stomach. It contracts to help food move to the stomach. As the toxins in alcohol flow down our esophagus, it can irritate and damage the lining — impacting proper digestion. 

It also relaxes the lower esophageal sphincter (a valve that separates the stomach from the esophagus) which makes it easier for stomach acid to flow back up, causing acid reflux and impaired movement of food and liquid to our stomach.

3. Stomach

Once alcohol reaches our stomach, about 20% is absorbed through our stomach lining. This means that any food we have in our stomach can slow down alcohol absorption. That’s why we commonly hear the recommendation to avoid drinking on an empty stomach

Like in other parts of the digestive tract, the toxins in alcohol irritate cells in our stomach lining, causing inflammation. Alcohol also increases stomach acid production, further increasing gut irritation and inflammation.

Our gut microbiome is full of healthy bacteria, which aids digestion and prevents overgrowth of harmful bacteria. However, alcohol destroys harmful bacteria, affecting not only digestion, but opening the door to certain bowel diseases such as IBD (inflammatory bowel disease).

4. Intestines

The majority of alcohol absorption happens in our small intestine due to the large surface area (roughly the size of a tennis court!). When our intestines are occupied with absorbing alcohol, focus is shifted away from their normal functions which include breaking down food, absorbing nutrients, extracting water, and moving the waste along to be eliminated.

Alcohol’s effects on our intestines impact intestinal motility (movement) and nutrient absorption, which is apparent in our post-drinking poops.

5. Liver

Our liver is tasked with breaking down a majority of the toxins in alcohol. It helps break down acetaldehyde into a less active compound, acetate, then water and carbon dioxide to be eliminated. 

However, we can only metabolize alcohol at a certain rate (roughly 1 standard drink per hour). When we drink more or faster than our liver can metabolize it, acetaldehyde builds up in our bloodstream, giving it more time to cause damage to our cells and organs.

Now that we understand how alcohol is metabolized and impacts each step of the digestive process, let’s zoom in on its effects on our bowel movements.

Alcohol’s Effects on Your Bowel Movements

Since alcohol affects every step of our digestive process, it can affect our “number two” in different ways. Here are some common experiences: 

1. Liquid Lament

Alcohol can lead to watery stools for several reasons. As we’ve discussed, alcohol impacts the function of our intestines. As it agitates our intestines, the muscles in our colon contract more frequently, pushing out our waste faster than normal. Since the process is sped up, our intestines don’t have time to digest properly, leading to diarrhea

Additionally, our large intestine typically expels water from our stool, which gives us solid poops that are easy to eliminate. When the function of our large intestine is impaired, water doesn’t get pulled out and again leaves us with watery stools. But alcohol can also have the opposite effect!

2. The “Slow-Go”

While some of us may find ourselves running to the toilet after drinking, others may find themselves sitting for longer than usual, due to constipation

Alcohol suppresses the secretion of vasopressin, which is the hormone that regulates water retention. This causes us to urinate more frequently, leading to dehydration. When we’re dehydrated, our intestines try to preserve water by absorbing fluids within our intestines. This leads to dry and hard stools that are difficult to pass.

Remember when we disclosed that alcohol can speed up motility in our intestines? Well, drinks with a higher alcohol content can actually slow down motility, leading to constipation. 

3. Excessive Trips to the Toilet 

As if that’s not enough, alcohol doesn’t just affect our poops, but also how often we go. Diarrhea and constipation can lead to excessive trips to the toilet.

Expedited digestion not only leads to watery stool, but can cause us to go more frequently. On the other hand, constipation can make it difficult for us to pass stool, causing several trips to the toilet in order for us to get it out.

4. Long-term Tummy Turmoil

Alcohol not only affects our stool right after drinking and the day after, while our body works to eliminate alcohol, but it can also cause damage to our digestive tract. It damages cells within our GI system and disrupts our gut microbiome. 

When there’s an overgrowth of harmful bacteria in our gut, we may experience negative effects such as constipation, bloating, and discomfort. Since our stomach lining is damaged, it’s also more permeable, allowing harmful bacteria to travel to different parts of our body in what’s known as leaky gut syndrome. 

Constant exposure to toxins can also lead to chronic digestive disorders such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD).

As we can see, “alcohol poops” vary widely. So what leads to these different experiences?

Alcohol’s Effects on Your Bowel Movements

What Influences Alcohol’s Effects on Your Bowel Movements?

To better avoid gut-wrenching bowel movements after drinking, let’s first dive into the factors that can influence it. It may go without saying that the amount of alcohol we drink matters. More alcohol means greater disruptions to our digestive system. But actually, the type of alcohol also plays a role. Research shows that alcoholic beverages with lower alcohol content more commonly cause watery stools whereas higher alcohol drinks more frequently cause constipation.

Individual differences impact the way we respond to alcohol. Genetic factors such as activity of the enzymes that break down alcohol (ADH and ALDH) can affect absorption and therefore breakdown and digestion. Other factors such as gut microbiome composition and pre-existing digestive conditions can put us at greater risk of bowel disruptions and developing bowel diseases.

Last but not least, food and water can also play a role. Having food in our stomach prior to drinking can slow down absorption and moderate alcohol’s effects. While eating before drinking alcohol is generally a good idea, specific foods such as spicy foods, caffeine, and refined sugars can exacerbate GI discomfort. Along with the food we eat, staying hydrated helps combat the dehydrating effects of alcohol and its effects on our bowel movements.

Managing and Preventing “Alcohol Poops”

“Alcohol poops” are unpleasant, to say the least. Now that we’ve dissected how alcohol impacts our digestive system and affects our number two, we can more effectively prevent and manage post-drinking bowel battles. Here are some effective strategies: 

  • Choose alternatives. Opt for non-alcoholic beverages to avoid alcohol’s harmful effects on our digestive tract. Better yet, choose digestion-friendly options such as kombucha, aloe vera juice, and kefir.
  • Follow moderation guidelines. If choosing to drink, stick to moderate drinking guidelines which is 2 drinks or less in a day for men and 1 drink or less in a day for women.
  • Avoid mixing alcohol and caffeine. Mixing alcohol and caffeine can be a recipe for disaster. Caffeine can further irritate our stomach and speed up our digestion, amplifying the negative effects of alcohol on our bowel movements. 
  • Stay hydrated. Drinking plenty of water helps things move smoothly through the digestive tract and helps prevent constipation.
  • Eat beforehand. Having food in our stomach helps slow down alcohol absorption and puts a barrier between the alcohol and our stomach lining. Eat a balanced meal with complex carbs, fiber, and protein for a smoother go the next day.
  • Maintain gut health. Managing our overall gut health through eating a healthy diet, managing stress, getting adequate sleep, and supplementing with pre- and probiotics helps mitigate some of the damage from alcohol. 
  • Seek support. If we’re concerned about our drinking habits or notice that alcohol is taking a toll on our gut health, we can reach out for support from others. Early intervention is the most effective way to prevent further damage from alcohol. Reach out to family and friends, join peer support groups, and explore treatment options.

“Alcohol poops” are just one way that alcohol’s detrimental effects on our health are visible. Quitting or cutting back on alcohol will be beneficial not only for our bowel health but also for our overall well-being. And don’t forget, Reframe is here to support you along the way!

Balancing Booze and Bowel Bliss

Some of us may have been aware that alcohol makes us pee more often, but alcohol can also affect our bowel movements, and not in a good way. It can cause effects on opposite sides of the spectrum from diarrhea to constipation. This is because of the toxic effects of alcohol on our digestive system. Not only can drinking cause short-term changes to our stool, but it can also lead to bowel diseases in the long term. Quitting or cutting back on alcohol helps us avoid throwing our bowel movements out of whack! 

You’re enjoying a night out with friends, cocktail in hand when suddenly the joy of the evening takes a sharp turn. You find yourself sprinting to the bathroom. Sound familiar? Alcohol can make us feel good in the moment, but it often leaves our digestive system in a state of turmoil. 

Let’s follow alcohol’s journey through our digestive system from the second it touches our lips through the egress of our intestines, which sometimes ends in an expedited or delayed release. Whether we’re looking to avoid the dreaded “alcohol poops” or aiming to improve our gut health, understanding how alcohol affects our digestive system can help keep our bathroom sprints at bay. Let’s dive into a less talked about side of alcohol — its effects on our bowel movements.

Understanding the Interaction: Alcohol Metabolism and Your Digestive System

A man holding his stomach

Alcohol, unlike the food and drinks we consume, is absorbed in the bloodstream, causing intoxication when our blood alcohol concentration rises. Although it’s absorbed into our bloodstream, each part of the digestive process is still involved in absorbing, processing, and breaking down alcohol (metabolization). Let’s follow the path of the digestive process to see how alcohol affects each stage.

1. Mouth and Throat

Although we associate our stomach and intestines with digestion, the process begins as soon as food or drink enters our mouth. When we drink alcohol, small amounts are absorbed through the lining of our mouth and throat. 

As the rest travels through the rest of the digestive tract, the alcohol that is absorbed into the blood begins to break down into a toxic compound known as acetaldehyde. 

Since alcohol is absorbed into our bloodstream, acetaldehyde not only damages our cells within our digestive system but also other parts of our body — explaining the many health conditions associated with drinking. But this is just the first step — let’s keep going!

2. Esophagus

The esophagus is like a muscular tube that connects our throat to our stomach. It contracts to help food move to the stomach. As the toxins in alcohol flow down our esophagus, it can irritate and damage the lining — impacting proper digestion. 

It also relaxes the lower esophageal sphincter (a valve that separates the stomach from the esophagus) which makes it easier for stomach acid to flow back up, causing acid reflux and impaired movement of food and liquid to our stomach.

3. Stomach

Once alcohol reaches our stomach, about 20% is absorbed through our stomach lining. This means that any food we have in our stomach can slow down alcohol absorption. That’s why we commonly hear the recommendation to avoid drinking on an empty stomach

Like in other parts of the digestive tract, the toxins in alcohol irritate cells in our stomach lining, causing inflammation. Alcohol also increases stomach acid production, further increasing gut irritation and inflammation.

Our gut microbiome is full of healthy bacteria, which aids digestion and prevents overgrowth of harmful bacteria. However, alcohol destroys harmful bacteria, affecting not only digestion, but opening the door to certain bowel diseases such as IBD (inflammatory bowel disease).

4. Intestines

The majority of alcohol absorption happens in our small intestine due to the large surface area (roughly the size of a tennis court!). When our intestines are occupied with absorbing alcohol, focus is shifted away from their normal functions which include breaking down food, absorbing nutrients, extracting water, and moving the waste along to be eliminated.

Alcohol’s effects on our intestines impact intestinal motility (movement) and nutrient absorption, which is apparent in our post-drinking poops.

5. Liver

Our liver is tasked with breaking down a majority of the toxins in alcohol. It helps break down acetaldehyde into a less active compound, acetate, then water and carbon dioxide to be eliminated. 

However, we can only metabolize alcohol at a certain rate (roughly 1 standard drink per hour). When we drink more or faster than our liver can metabolize it, acetaldehyde builds up in our bloodstream, giving it more time to cause damage to our cells and organs.

Now that we understand how alcohol is metabolized and impacts each step of the digestive process, let’s zoom in on its effects on our bowel movements.

Alcohol’s Effects on Your Bowel Movements

Since alcohol affects every step of our digestive process, it can affect our “number two” in different ways. Here are some common experiences: 

1. Liquid Lament

Alcohol can lead to watery stools for several reasons. As we’ve discussed, alcohol impacts the function of our intestines. As it agitates our intestines, the muscles in our colon contract more frequently, pushing out our waste faster than normal. Since the process is sped up, our intestines don’t have time to digest properly, leading to diarrhea

Additionally, our large intestine typically expels water from our stool, which gives us solid poops that are easy to eliminate. When the function of our large intestine is impaired, water doesn’t get pulled out and again leaves us with watery stools. But alcohol can also have the opposite effect!

2. The “Slow-Go”

While some of us may find ourselves running to the toilet after drinking, others may find themselves sitting for longer than usual, due to constipation

Alcohol suppresses the secretion of vasopressin, which is the hormone that regulates water retention. This causes us to urinate more frequently, leading to dehydration. When we’re dehydrated, our intestines try to preserve water by absorbing fluids within our intestines. This leads to dry and hard stools that are difficult to pass.

Remember when we disclosed that alcohol can speed up motility in our intestines? Well, drinks with a higher alcohol content can actually slow down motility, leading to constipation. 

3. Excessive Trips to the Toilet 

As if that’s not enough, alcohol doesn’t just affect our poops, but also how often we go. Diarrhea and constipation can lead to excessive trips to the toilet.

Expedited digestion not only leads to watery stool, but can cause us to go more frequently. On the other hand, constipation can make it difficult for us to pass stool, causing several trips to the toilet in order for us to get it out.

4. Long-term Tummy Turmoil

Alcohol not only affects our stool right after drinking and the day after, while our body works to eliminate alcohol, but it can also cause damage to our digestive tract. It damages cells within our GI system and disrupts our gut microbiome. 

When there’s an overgrowth of harmful bacteria in our gut, we may experience negative effects such as constipation, bloating, and discomfort. Since our stomach lining is damaged, it’s also more permeable, allowing harmful bacteria to travel to different parts of our body in what’s known as leaky gut syndrome. 

Constant exposure to toxins can also lead to chronic digestive disorders such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD).

As we can see, “alcohol poops” vary widely. So what leads to these different experiences?

Alcohol’s Effects on Your Bowel Movements

What Influences Alcohol’s Effects on Your Bowel Movements?

To better avoid gut-wrenching bowel movements after drinking, let’s first dive into the factors that can influence it. It may go without saying that the amount of alcohol we drink matters. More alcohol means greater disruptions to our digestive system. But actually, the type of alcohol also plays a role. Research shows that alcoholic beverages with lower alcohol content more commonly cause watery stools whereas higher alcohol drinks more frequently cause constipation.

Individual differences impact the way we respond to alcohol. Genetic factors such as activity of the enzymes that break down alcohol (ADH and ALDH) can affect absorption and therefore breakdown and digestion. Other factors such as gut microbiome composition and pre-existing digestive conditions can put us at greater risk of bowel disruptions and developing bowel diseases.

Last but not least, food and water can also play a role. Having food in our stomach prior to drinking can slow down absorption and moderate alcohol’s effects. While eating before drinking alcohol is generally a good idea, specific foods such as spicy foods, caffeine, and refined sugars can exacerbate GI discomfort. Along with the food we eat, staying hydrated helps combat the dehydrating effects of alcohol and its effects on our bowel movements.

Managing and Preventing “Alcohol Poops”

“Alcohol poops” are unpleasant, to say the least. Now that we’ve dissected how alcohol impacts our digestive system and affects our number two, we can more effectively prevent and manage post-drinking bowel battles. Here are some effective strategies: 

  • Choose alternatives. Opt for non-alcoholic beverages to avoid alcohol’s harmful effects on our digestive tract. Better yet, choose digestion-friendly options such as kombucha, aloe vera juice, and kefir.
  • Follow moderation guidelines. If choosing to drink, stick to moderate drinking guidelines which is 2 drinks or less in a day for men and 1 drink or less in a day for women.
  • Avoid mixing alcohol and caffeine. Mixing alcohol and caffeine can be a recipe for disaster. Caffeine can further irritate our stomach and speed up our digestion, amplifying the negative effects of alcohol on our bowel movements. 
  • Stay hydrated. Drinking plenty of water helps things move smoothly through the digestive tract and helps prevent constipation.
  • Eat beforehand. Having food in our stomach helps slow down alcohol absorption and puts a barrier between the alcohol and our stomach lining. Eat a balanced meal with complex carbs, fiber, and protein for a smoother go the next day.
  • Maintain gut health. Managing our overall gut health through eating a healthy diet, managing stress, getting adequate sleep, and supplementing with pre- and probiotics helps mitigate some of the damage from alcohol. 
  • Seek support. If we’re concerned about our drinking habits or notice that alcohol is taking a toll on our gut health, we can reach out for support from others. Early intervention is the most effective way to prevent further damage from alcohol. Reach out to family and friends, join peer support groups, and explore treatment options.

“Alcohol poops” are just one way that alcohol’s detrimental effects on our health are visible. Quitting or cutting back on alcohol will be beneficial not only for our bowel health but also for our overall well-being. And don’t forget, Reframe is here to support you along the way!

Balancing Booze and Bowel Bliss

Some of us may have been aware that alcohol makes us pee more often, but alcohol can also affect our bowel movements, and not in a good way. It can cause effects on opposite sides of the spectrum from diarrhea to constipation. This is because of the toxic effects of alcohol on our digestive system. Not only can drinking cause short-term changes to our stool, but it can also lead to bowel diseases in the long term. Quitting or cutting back on alcohol helps us avoid throwing our bowel movements out of whack! 

Alcohol and Health
2024-10-08 9:00
Alcohol and Health
Understanding the Maddrey Score
This is some text inside of a div block.

Our Maddrey score is a helpful tool that determines the severity of alcohol-related liver disease. Check out our latest blog for more info on how it’s calculated and why it matters.

18 min read

Maintain Proper Liver Function With Reframe!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet hundreds of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!

Read Full Article  →

Imagine you’re sitting in the doctor’s office after deciding to take charge of your liver health. You’re determined, hopeful, and ready for the changes ahead, but then your doctor mentions something about the “Maddrey score.” Suddenly, you find yourself confused, a little anxious, and unsure what this number means for your future and your path to better health.

A diverse group of individuals engaged in conversation around a table

While the Maddrey score can seem intimidating, it actually provides valuable insight into our liver health. It’s a helpful guide in determining the appropriate treatment and lifestyle changes we should make to improve our liver health. Let’s unpack what the Maddrey score is and how to calculate it to help start our journey to healing our liver.

What Is the Maddrey Score?

The Maddrey score or Maddrey discriminant function is a tool used to determine the severity of alcoholic hepatitis (a form of alcohol-related liver disease). It uses scores from different blood tests, which gives us insight into the functioning of our liver. Think of it as a report card for our liver health. 

Our doctor uses the Maddrey score to get a better idea of the outlook of our condition and help develop an appropriate treatment plan. This insight is particularly important to help us navigate the complexities of alcoholic hepatitis and work towards achieving a better prognosis. (To learn whether your current drinking habits are causing liver damage and warrant Maddrey score evaluation, check out “How Much Alcohol Causes Liver Damage?”) 

Now that we’re familiar with the Maddrey score’s role in assessing our liver health, let’s dive deeper into the specifics of alcoholic hepatitis and how it impacts our liver.

The Basics of Alcoholic Hepatitis

Alcoholic hepatitis is acute liver inflammation due to excessive alcohol consumption. Since our liver is in charge of breaking down the toxins in alcohol, too much alcohol overloads the liver and damages the tissues. 

Over time, inflammation can lead to liver scarring and cirrhosis (permanent scarring that impairs liver function). Alcoholic hepatitis can range from mild to severe and symptoms include fatigue, weight loss, changes in appetite, pain or swelling in the abdomen, and jaundice. The condition is associated with a high mortality rate, and treatment usually depends on the severity of the condition. This is where the Maddrey score comes in handy.

Components of the Maddrey Discriminant Function (MDF) Score

The MDF score is made up of two main components. The first is how long it takes for our blood to clot (prothrombin time). Prothrombin is a protein made by the liver that helps our blood clot. A high prothrombin time means it takes longer for our blood to clot, which happens when our liver isn’t producing an adequate amount of blood-clotting proteins. 

The second part of the MDF score is our serum bilirubin level. Bilirubin is a substance our body produces to break down old red blood cells. A healthy liver is able to get rid of bilirubin, but for those with liver problems, bilirubin can build up to abnormal levels, leading to symptoms such as dark-colored urine and yellowing of the skin and eyes (jaundice).

We can calculate our Maddrey score using the discrimination function:

Bilirubin (mg/dL) + 4.6 x (prothrombin time - control time)

Or, there are also online Maddrey score calculators that do the work for us (assuming we have all the data from a doctor after having our tests done — don’t try to test your own blood at home!). Now that we’ve figured out our Maddrey score, what does it mean? 

Reading the Maddrey Score

If our Maddrey score is less than 32, we have mild to moderate hepatitis. While it’s named “mild to moderate,” alcoholic hepatitis is a serious condition even at a less severe level. A study found that moderate alcoholic hepatitis has a 6% mortality rate at 28 days and 13% at the one-year mark. While mild to moderate alcoholic hepatitis is miles more favorable than its severe form, it should be taken seriously. 

If our Maddrey score is over 32, this means that we have severe alcoholic hepatitis. Severe alcohol hepatitis means that the damage to our liver can quickly lead to permanent liver damage and failure that can be life-threatening. Severe alcoholic hepatitis has a 6-month mortality rate of about 40% after the onset of the condition. However, aggressive management of the condition and younger age may improve our outlook. 

So, although the Maddrey score is just a number, it helps us get a clearer picture of the severity of liver damage from alcohol and guides us toward the best treatment options to improve our liver health.

Understanding the Maddrey Score and Supporting Treatments

Treating Alcoholic Hepatitis: Application of the Maddrey Score

The type of treatment depends on individual factors, but more so on the severity of the condition. For mild to moderate alcoholic hepatitis, liver damage can often be reversed, and treatment includes more lifestyle changes. 

  • Nutritional support. Malnutrition is common with alcoholic hepatitis due to impaired nutrient absorption, and is also associated with increased mortality rate. Nutritional support for those with alcohol hepatitis typically includes consuming 1.5 grams of protein per kg of body weight and around 30-40 calories per kg of body weight per day. Supplementation of micronutrients such as zinc, folate, thiamine, pyridoxine, and vitamins B, A, D, and E help replenish deficiencies caused by alcohol. 
  • Abstinence from alcohol. Avoiding alcohol is crucial in preventing further damage to our liver. Abstinence also gives the liver a break and a chance to heal. To get a better idea of how long this may take, check out “How Long Does It Take for the Liver to Heal From Alcohol Misuse?”.
  • Supportive treatments. Heavy drinking is associated with many health issues that can impact our liver health. Supportive treatments for conditions such as diabetes, obesity, and other complications may also be treated. 

The Maddrey score is especially helpful in determining whether extensive treatment is needed. Severe alcoholic hepatitis is frequently treated with medications that reduce inflammation and immune system activity (corticosteroids) or medications used to increase blood flow through the blood vessels (pentoxifylline). While corticosteroids can help treat severe liver damage, they can be unsafe for people in the following categories or with the following conditions:

  • Are over 50 years old 
  • Have uncontrolled diabetes
  • Have previous kidney injury
  • Have persistent high levels of bilirubin
  • Choose to continue to drink alcohol 
  • Experience upper GI bleeding
  • Have pancreatitis
  • Have signs of hepatic encephalopathy (loss of brain function from damaged liver)

Your doctor will utilize the Maddrey score as well as other individual factors to decide if corticosteroid therapy is the best plan of action. Along with pharmacological treatments, quitting alcohol is critical to ensuring severe alcoholic hepatitis doesn’t progress, and to increase our chances of survival. Doctors may also order other tests to better distinguish between different liver disorders and to get a clearer picture of our liver function and health.

Other Tests for Liver Function

While the Maddrey score is a great diagnostic and prognostic tool for alcoholic hepatitis, other liver function tests give us a clearer picture of our liver health and further guide our plan of treatment. The more we know, the more informed the choices we can make! Liver function panels usually include a range of tests: 

  • Mitochondrial antibodies test. This test looks for antibodies that are commonly produced if we have primary biliary cirrhosis (bile buildup that leads to liver scarring), chronic active hepatitis, and other autoimmune disorders
  • Alanine transaminase (ALT) test. This enzyme is found predominantly in the liver and is released into the bloodstream after acute liver damage. If ALT is high, it’s a good indicator of liver damage.
  • Aspartate transaminase (AST) test. AST is an enzyme that exists in our liver. When liver cells are damaged, AST can leak into our bloodstream, causing abnormally high levels. With other tests, AST can be an indicator of liver damage and other health issues.
  • Gamma-glutamyl transpeptidase (GGT) test. GGT is often administered with other tests to distinguish between liver and bone disease. Since ALT can be elevated due to bone disease, GGT can be an illuminating factor. The enzyme is usually elevated when there’s an obstruction to our bile ducts that carry bile from the liver to our intestines. 
  • Lactic dehydrogenase (LDH) test. LDH is a type of protein that’s released when our tissues are damaged. There are five types of LDH enzymes known as isoenzymes. LDH-5 is the isoenzyme found mainly in our liver and skeletal muscle, helping us specifically detect liver damage.

After using the Maddrey score and other liver function tests, our doctor may recommend pharmacological treatments, nutritional support, and the cornerstone of alcoholic hepatitis treatment — lifestyle changes to improve our liver health and function.

Beyond Maddrey’s Discriminant Function: Maintaining a Healthy Liver 

As we’ve learned, alcoholic hepatitis is a serious condition that can be life-threatening. Taking these steps to maintain a healthy liver can reduce the risk of alcoholic hepatitis or reverse liver damage: 

  • Look out for signs of liver dysfunction. Signs of liver dysfunction including pain, jaundice, fatigue, and unexplained weight loss are not always apparent in the early stages. However, alcohol withdrawal symptoms are common in those of us with alcoholic hepatitis and can be a warning sign to check liver function even if no other signs are present. 
  • Take liver function tests. Signs of liver dysfunction aren’t always apparent until the later stages. If we’re concerned about our liver health, we can talk to our doctor about regular liver function tests, and there are even options to take liver function tests at home.
  • Avoid toxic substances. Our liver is in charge of getting rid of toxic substances in our body. Avoid toxic substances such as alcohol, medications, and other drugs
  • Maintain a healthy diet. Eating a balanced liver-healthy diet low in processed foods and added sugars helps us maintain a healthy weight and prevent excess fat buildup in our liver. On top of that, give your liver another health boost by trying liver detox drinks.
  • Get adequate exercise. Staying active improves blood flow to the liver, decreases inflammation, and prevents excess fat buildup which can impair normal liver functioning. 
  • Seek support. Quitting or cutting back on alcohol is crucial in preventing alcoholic hepatitis and maintaining a healthy liver, but it's not always easy. We can explore different treatment options to help us through the journey and regain control of our liver health and relationship with alcohol. 

These strategies not only help us prevent alcoholic hepatitis by maintaining a healthy liver, but also help us take intentional steps to improve our liver health after our Maddrey score raises a red flag. 

A Clearer Picture

The Maddrey score is just a number, but this number is critical in helping us understand how much liver damage we have from alcohol. It not only helps our doctor determine the best treatment options for us but also gives us an idea of what our outlook may be. Alcoholic hepatitis is a severe form of alcohol-related liver disease that can be life-threatening. While alcoholic hepatitis can be treated to a certain extent, the most effective way to prevent and stop liver damage is to quit alcohol, a substance that is undoubtedly toxic to our liver. 

Imagine you’re sitting in the doctor’s office after deciding to take charge of your liver health. You’re determined, hopeful, and ready for the changes ahead, but then your doctor mentions something about the “Maddrey score.” Suddenly, you find yourself confused, a little anxious, and unsure what this number means for your future and your path to better health.

A diverse group of individuals engaged in conversation around a table

While the Maddrey score can seem intimidating, it actually provides valuable insight into our liver health. It’s a helpful guide in determining the appropriate treatment and lifestyle changes we should make to improve our liver health. Let’s unpack what the Maddrey score is and how to calculate it to help start our journey to healing our liver.

What Is the Maddrey Score?

The Maddrey score or Maddrey discriminant function is a tool used to determine the severity of alcoholic hepatitis (a form of alcohol-related liver disease). It uses scores from different blood tests, which gives us insight into the functioning of our liver. Think of it as a report card for our liver health. 

Our doctor uses the Maddrey score to get a better idea of the outlook of our condition and help develop an appropriate treatment plan. This insight is particularly important to help us navigate the complexities of alcoholic hepatitis and work towards achieving a better prognosis. (To learn whether your current drinking habits are causing liver damage and warrant Maddrey score evaluation, check out “How Much Alcohol Causes Liver Damage?”) 

Now that we’re familiar with the Maddrey score’s role in assessing our liver health, let’s dive deeper into the specifics of alcoholic hepatitis and how it impacts our liver.

The Basics of Alcoholic Hepatitis

Alcoholic hepatitis is acute liver inflammation due to excessive alcohol consumption. Since our liver is in charge of breaking down the toxins in alcohol, too much alcohol overloads the liver and damages the tissues. 

Over time, inflammation can lead to liver scarring and cirrhosis (permanent scarring that impairs liver function). Alcoholic hepatitis can range from mild to severe and symptoms include fatigue, weight loss, changes in appetite, pain or swelling in the abdomen, and jaundice. The condition is associated with a high mortality rate, and treatment usually depends on the severity of the condition. This is where the Maddrey score comes in handy.

Components of the Maddrey Discriminant Function (MDF) Score

The MDF score is made up of two main components. The first is how long it takes for our blood to clot (prothrombin time). Prothrombin is a protein made by the liver that helps our blood clot. A high prothrombin time means it takes longer for our blood to clot, which happens when our liver isn’t producing an adequate amount of blood-clotting proteins. 

The second part of the MDF score is our serum bilirubin level. Bilirubin is a substance our body produces to break down old red blood cells. A healthy liver is able to get rid of bilirubin, but for those with liver problems, bilirubin can build up to abnormal levels, leading to symptoms such as dark-colored urine and yellowing of the skin and eyes (jaundice).

We can calculate our Maddrey score using the discrimination function:

Bilirubin (mg/dL) + 4.6 x (prothrombin time - control time)

Or, there are also online Maddrey score calculators that do the work for us (assuming we have all the data from a doctor after having our tests done — don’t try to test your own blood at home!). Now that we’ve figured out our Maddrey score, what does it mean? 

Reading the Maddrey Score

If our Maddrey score is less than 32, we have mild to moderate hepatitis. While it’s named “mild to moderate,” alcoholic hepatitis is a serious condition even at a less severe level. A study found that moderate alcoholic hepatitis has a 6% mortality rate at 28 days and 13% at the one-year mark. While mild to moderate alcoholic hepatitis is miles more favorable than its severe form, it should be taken seriously. 

If our Maddrey score is over 32, this means that we have severe alcoholic hepatitis. Severe alcohol hepatitis means that the damage to our liver can quickly lead to permanent liver damage and failure that can be life-threatening. Severe alcoholic hepatitis has a 6-month mortality rate of about 40% after the onset of the condition. However, aggressive management of the condition and younger age may improve our outlook. 

So, although the Maddrey score is just a number, it helps us get a clearer picture of the severity of liver damage from alcohol and guides us toward the best treatment options to improve our liver health.

Understanding the Maddrey Score and Supporting Treatments

Treating Alcoholic Hepatitis: Application of the Maddrey Score

The type of treatment depends on individual factors, but more so on the severity of the condition. For mild to moderate alcoholic hepatitis, liver damage can often be reversed, and treatment includes more lifestyle changes. 

  • Nutritional support. Malnutrition is common with alcoholic hepatitis due to impaired nutrient absorption, and is also associated with increased mortality rate. Nutritional support for those with alcohol hepatitis typically includes consuming 1.5 grams of protein per kg of body weight and around 30-40 calories per kg of body weight per day. Supplementation of micronutrients such as zinc, folate, thiamine, pyridoxine, and vitamins B, A, D, and E help replenish deficiencies caused by alcohol. 
  • Abstinence from alcohol. Avoiding alcohol is crucial in preventing further damage to our liver. Abstinence also gives the liver a break and a chance to heal. To get a better idea of how long this may take, check out “How Long Does It Take for the Liver to Heal From Alcohol Misuse?”.
  • Supportive treatments. Heavy drinking is associated with many health issues that can impact our liver health. Supportive treatments for conditions such as diabetes, obesity, and other complications may also be treated. 

The Maddrey score is especially helpful in determining whether extensive treatment is needed. Severe alcoholic hepatitis is frequently treated with medications that reduce inflammation and immune system activity (corticosteroids) or medications used to increase blood flow through the blood vessels (pentoxifylline). While corticosteroids can help treat severe liver damage, they can be unsafe for people in the following categories or with the following conditions:

  • Are over 50 years old 
  • Have uncontrolled diabetes
  • Have previous kidney injury
  • Have persistent high levels of bilirubin
  • Choose to continue to drink alcohol 
  • Experience upper GI bleeding
  • Have pancreatitis
  • Have signs of hepatic encephalopathy (loss of brain function from damaged liver)

Your doctor will utilize the Maddrey score as well as other individual factors to decide if corticosteroid therapy is the best plan of action. Along with pharmacological treatments, quitting alcohol is critical to ensuring severe alcoholic hepatitis doesn’t progress, and to increase our chances of survival. Doctors may also order other tests to better distinguish between different liver disorders and to get a clearer picture of our liver function and health.

Other Tests for Liver Function

While the Maddrey score is a great diagnostic and prognostic tool for alcoholic hepatitis, other liver function tests give us a clearer picture of our liver health and further guide our plan of treatment. The more we know, the more informed the choices we can make! Liver function panels usually include a range of tests: 

  • Mitochondrial antibodies test. This test looks for antibodies that are commonly produced if we have primary biliary cirrhosis (bile buildup that leads to liver scarring), chronic active hepatitis, and other autoimmune disorders
  • Alanine transaminase (ALT) test. This enzyme is found predominantly in the liver and is released into the bloodstream after acute liver damage. If ALT is high, it’s a good indicator of liver damage.
  • Aspartate transaminase (AST) test. AST is an enzyme that exists in our liver. When liver cells are damaged, AST can leak into our bloodstream, causing abnormally high levels. With other tests, AST can be an indicator of liver damage and other health issues.
  • Gamma-glutamyl transpeptidase (GGT) test. GGT is often administered with other tests to distinguish between liver and bone disease. Since ALT can be elevated due to bone disease, GGT can be an illuminating factor. The enzyme is usually elevated when there’s an obstruction to our bile ducts that carry bile from the liver to our intestines. 
  • Lactic dehydrogenase (LDH) test. LDH is a type of protein that’s released when our tissues are damaged. There are five types of LDH enzymes known as isoenzymes. LDH-5 is the isoenzyme found mainly in our liver and skeletal muscle, helping us specifically detect liver damage.

After using the Maddrey score and other liver function tests, our doctor may recommend pharmacological treatments, nutritional support, and the cornerstone of alcoholic hepatitis treatment — lifestyle changes to improve our liver health and function.

Beyond Maddrey’s Discriminant Function: Maintaining a Healthy Liver 

As we’ve learned, alcoholic hepatitis is a serious condition that can be life-threatening. Taking these steps to maintain a healthy liver can reduce the risk of alcoholic hepatitis or reverse liver damage: 

  • Look out for signs of liver dysfunction. Signs of liver dysfunction including pain, jaundice, fatigue, and unexplained weight loss are not always apparent in the early stages. However, alcohol withdrawal symptoms are common in those of us with alcoholic hepatitis and can be a warning sign to check liver function even if no other signs are present. 
  • Take liver function tests. Signs of liver dysfunction aren’t always apparent until the later stages. If we’re concerned about our liver health, we can talk to our doctor about regular liver function tests, and there are even options to take liver function tests at home.
  • Avoid toxic substances. Our liver is in charge of getting rid of toxic substances in our body. Avoid toxic substances such as alcohol, medications, and other drugs
  • Maintain a healthy diet. Eating a balanced liver-healthy diet low in processed foods and added sugars helps us maintain a healthy weight and prevent excess fat buildup in our liver. On top of that, give your liver another health boost by trying liver detox drinks.
  • Get adequate exercise. Staying active improves blood flow to the liver, decreases inflammation, and prevents excess fat buildup which can impair normal liver functioning. 
  • Seek support. Quitting or cutting back on alcohol is crucial in preventing alcoholic hepatitis and maintaining a healthy liver, but it's not always easy. We can explore different treatment options to help us through the journey and regain control of our liver health and relationship with alcohol. 

These strategies not only help us prevent alcoholic hepatitis by maintaining a healthy liver, but also help us take intentional steps to improve our liver health after our Maddrey score raises a red flag. 

A Clearer Picture

The Maddrey score is just a number, but this number is critical in helping us understand how much liver damage we have from alcohol. It not only helps our doctor determine the best treatment options for us but also gives us an idea of what our outlook may be. Alcoholic hepatitis is a severe form of alcohol-related liver disease that can be life-threatening. While alcoholic hepatitis can be treated to a certain extent, the most effective way to prevent and stop liver damage is to quit alcohol, a substance that is undoubtedly toxic to our liver. 

Alcohol and Health
2024-10-05 9:00
Alcohol and Health
Alcohol’s Role in Chronic Pain
This is some text inside of a div block.

Alcohol negatively affects chronic pain in direct and indirect ways. Check out our latest blog for more info on the short and long-term effects of alcohol on pain.

14 min read

Improve Your Physical Health With Reframe!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet hundreds of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!

Read Full Article  →

It’s been a long week, and you finally settle in on the couch with a glass of wine, hoping to unwind. The warmth spreads through you, taking the edge off that persistent ache in your back — the one that’s been nagging you for days. For a moment, you feel some relief as the pain fades. But when morning comes, the pain is back — stronger, more stubborn, and now with a headache to match. 

For those living with chronic pain, this may be a familiar scenario. Alcohol might seem like a quick fix, but its role in the cycle of pain is far from simple. Let’s delve into how alcohol affects chronic pain, and what that means for those of us who are seeking real, lasting relief. 

Does Alcohol Help With Pain?

Perhaps you bumped your knee on the corner of the table and didn’t feel it until the day after drinking. Or, the ache in your lower back seems to disappear after a drink or two. Now you’re left wondering, “Does alcohol numb pain?” To a certain extent it does — but not without drawbacks.

Alcohol reduces the perception of pain. So, it’s not that we’re any less hurt or that alcohol makes the pain go away, it’s that the messaging within our brain and body get disrupted, and we don’t register the signal of pain as well. Because of this, alcohol can seem like a quick fix for pain. But there’s more to the story. 

Using alcohol as a pain reliever can lead to many issues (which we’ll go into more detail on later). One of these issues is actually worse pain. What started out as an injury that just needed time to heal can become a lingering and chronic issue. 

What Is Chronic Pain?

Chronic pain is pain that lasts longer than its normal healing time. It can be continuous pain, or it can come and go but persist for a prolonged period of time. Some causes of chronic pain include injuries, health conditions or diseases, and even psychological issues. 

The main symptom of chronic pain is, of course, pain, but it can also cause a range of other symptoms such as fatigue, appetite loss, trouble sleeping, and mood changes. 

As we can see, chronic pain can significantly impact our quality of life. When we add alcohol to the equation, things can get even worse.

Alcohol’s Direct Impact on Chronic Pain

Excessive and chronic drinking can actually cause chronic pain. Here’s why:

  • Alcohol damages our nerves. Alcohol is toxic to our nerve cells, impairing their ability to transmit signals effectively. Over time, this leads to nerve damage, known as alcoholic neuropathy. Symptoms include tingling, numbness, burning sensations, and sharp pain. 
  • Alcohol changes the way our brain processes pain. Alcohol interferes with our brain’s chemical messengers (neurotransmitters). Specifically, it disrupts neurotransmitters involved in pain regulation, such as serotonin and gamma-aminobutyric acid (GABA). This disruption can heighten pain sensitivity in the long run, leading to or adding to chronic pain.
  • Alcohol impacts the activation of our immune system. Alcohol weakens our immune system, making it less effective at fighting off infections and repairing tissues. This is because alcohol disrupts the balance of pro-inflammatory and anti-inflammatory cytokines, which are signaling molecules that regulate our immune response. An impaired immune response can contribute to exacerbated pain and hinder healing.
  • Alcohol causes chronic inflammation. It does this by increasing the production of inflammatory markers like cytokines. This leads to tissue damage and, as a result, worse pain. Inflammation is an underlying factor in many chronic pain conditions such as arthritis and fibromyalgia. 

If we already experience chronic pain, these issues can add to it, compounding the effects. But that’s not all: alcohol can worsen chronic pain in more obscure ways. 

Alcohol’s Indirect Impact on Chronic Pain

Alcohol’s Indirect Impact on Chronic Pain

Alcohol has negative impacts on different aspects of our lives, many of which contribute to pain. The combination of these factors can make chronic pain even worse: 

  • Poor sleep quality. Drinking disrupts our REM sleep. So, even though we might fall asleep quickly, our sleep quality may be lacking. Research shows that sleeping reduces inflammation, promotes cell regeneration, and increases pain sensitivity — all of which help reduce pain. 
  • Increased stress. Alcohol alters our brain chemistry, leading to anxiety and stress that can intensify our perception of pain. In one study, participants who were stressed had lower pain tolerance during the cold pressor test (a procedure that induces stress by immersing a limb in cold water for a period of time). Added stress also triggers the body’s inflammatory response, worsening chronic pain symptoms. 
  • Other health issues. Alcohol is toxic to our body. Every time we drink, it not only disrupts normal bodily functions but also damages our cells and organs. This can lead to many health issues, including liver damage, hypertension, diabetes, cardiovascular disease, GI discomfort, and much more. Symptoms of these health conditions can involve inflammation and pain, adding to our chronic pain. 

As we can see, alcohol contributes to chronic pain in many ways. So, can we still drink?

Can You Drink Alcohol With Chronic Pain?

Drinking alcohol with chronic pain isn’t recommended. Not only can it worsen chronic pain, but it also can create a cycle of dependence. 

Let’s say we’re sick and tired of the constant pain, and we decide to have a drink to take the edge off. It might numb the pain temporarily, but at a cost. When we drink, our brain releases serotonin and dopamine (our brain’s “feel good” hormones), which help us relax in the moment and feel a sense of pleasure. Alcohol can also help us relax physiologically by slowing down our heartbeat and releasing tension in our muscles (again, temporarily). These things alone can take over our brain’s reward system and drive us to come back for more.

When we add pain relief to that, our desire to drink can increase, heightening our risk of dependence. In this way, the consequences of drinking with chronic pain become greater, and our goal — relieving our pain — becomes all the more remote.

Alcohol not only worsens chronic pain but also leads to many other health issues. So, if alcohol isn’t a viable solution for pain relief, what is?

Tips for Living Pain-Free

There is no current cure for chronic pain,but making positive lifestyle changes can help manage it. Here are several strategies to consider:

  • Gentle exercise. Gentle stretching or low-impact movement such as walking, yoga, and Pilates increases blood flow and produces endorphins, which promote overall well-being without putting too much stress on our body and lead to more pain. 
  • Anti-inflammatory diet. Nutrition plays a key role in healing and reducing inflammation. Eat a diet rich in fruits, vegetables, whole grains, and healthy fats. 
  • Sleep aids. Sleep is essential for healing and reducing stress. But pain can impact our sleep, creating a vicious cycle where we lack rest and have more pain. Try sleep aids such as magnesium, melatonin, and even meditation to get a more well-rested night of sleep.
  • Stress management. Managing stress can help relieve pain. Try disconnecting from social media, spending time in nature, journaling, or exploring hobbies.
  • Alternative treatments. Holistic treatments such as acupuncture, cryotherapy, and red light therapy have also been found to reduce pain by addressing different facets of our health. 
  • Community support. Engaging with others who may be going through a similar experience, venting with those who can empathize, and getting professional advice can help us navigate the journey to better health with a sense of connection and empowerment. 

A life with less pain is within reach when we make these positive lifestyle changes! On top of that, our overall health will improve so we can enjoy a better quality of life.

Key Takeaways

While alcohol might offer temporary pain relief, its long-term effects often exacerbate the problem, leading to a cycle of increased pain and reliance that’s difficult to break. Now that we understand the major role that alcohol can play in chronic pain, we can implement healthier, more sustainable ways to manage it. We can break free from this cycle and work towards a pain-free life by quitting or cutting back on alcohol.

It’s been a long week, and you finally settle in on the couch with a glass of wine, hoping to unwind. The warmth spreads through you, taking the edge off that persistent ache in your back — the one that’s been nagging you for days. For a moment, you feel some relief as the pain fades. But when morning comes, the pain is back — stronger, more stubborn, and now with a headache to match. 

For those living with chronic pain, this may be a familiar scenario. Alcohol might seem like a quick fix, but its role in the cycle of pain is far from simple. Let’s delve into how alcohol affects chronic pain, and what that means for those of us who are seeking real, lasting relief. 

Does Alcohol Help With Pain?

Perhaps you bumped your knee on the corner of the table and didn’t feel it until the day after drinking. Or, the ache in your lower back seems to disappear after a drink or two. Now you’re left wondering, “Does alcohol numb pain?” To a certain extent it does — but not without drawbacks.

Alcohol reduces the perception of pain. So, it’s not that we’re any less hurt or that alcohol makes the pain go away, it’s that the messaging within our brain and body get disrupted, and we don’t register the signal of pain as well. Because of this, alcohol can seem like a quick fix for pain. But there’s more to the story. 

Using alcohol as a pain reliever can lead to many issues (which we’ll go into more detail on later). One of these issues is actually worse pain. What started out as an injury that just needed time to heal can become a lingering and chronic issue. 

What Is Chronic Pain?

Chronic pain is pain that lasts longer than its normal healing time. It can be continuous pain, or it can come and go but persist for a prolonged period of time. Some causes of chronic pain include injuries, health conditions or diseases, and even psychological issues. 

The main symptom of chronic pain is, of course, pain, but it can also cause a range of other symptoms such as fatigue, appetite loss, trouble sleeping, and mood changes. 

As we can see, chronic pain can significantly impact our quality of life. When we add alcohol to the equation, things can get even worse.

Alcohol’s Direct Impact on Chronic Pain

Excessive and chronic drinking can actually cause chronic pain. Here’s why:

  • Alcohol damages our nerves. Alcohol is toxic to our nerve cells, impairing their ability to transmit signals effectively. Over time, this leads to nerve damage, known as alcoholic neuropathy. Symptoms include tingling, numbness, burning sensations, and sharp pain. 
  • Alcohol changes the way our brain processes pain. Alcohol interferes with our brain’s chemical messengers (neurotransmitters). Specifically, it disrupts neurotransmitters involved in pain regulation, such as serotonin and gamma-aminobutyric acid (GABA). This disruption can heighten pain sensitivity in the long run, leading to or adding to chronic pain.
  • Alcohol impacts the activation of our immune system. Alcohol weakens our immune system, making it less effective at fighting off infections and repairing tissues. This is because alcohol disrupts the balance of pro-inflammatory and anti-inflammatory cytokines, which are signaling molecules that regulate our immune response. An impaired immune response can contribute to exacerbated pain and hinder healing.
  • Alcohol causes chronic inflammation. It does this by increasing the production of inflammatory markers like cytokines. This leads to tissue damage and, as a result, worse pain. Inflammation is an underlying factor in many chronic pain conditions such as arthritis and fibromyalgia. 

If we already experience chronic pain, these issues can add to it, compounding the effects. But that’s not all: alcohol can worsen chronic pain in more obscure ways. 

Alcohol’s Indirect Impact on Chronic Pain

Alcohol’s Indirect Impact on Chronic Pain

Alcohol has negative impacts on different aspects of our lives, many of which contribute to pain. The combination of these factors can make chronic pain even worse: 

  • Poor sleep quality. Drinking disrupts our REM sleep. So, even though we might fall asleep quickly, our sleep quality may be lacking. Research shows that sleeping reduces inflammation, promotes cell regeneration, and increases pain sensitivity — all of which help reduce pain. 
  • Increased stress. Alcohol alters our brain chemistry, leading to anxiety and stress that can intensify our perception of pain. In one study, participants who were stressed had lower pain tolerance during the cold pressor test (a procedure that induces stress by immersing a limb in cold water for a period of time). Added stress also triggers the body’s inflammatory response, worsening chronic pain symptoms. 
  • Other health issues. Alcohol is toxic to our body. Every time we drink, it not only disrupts normal bodily functions but also damages our cells and organs. This can lead to many health issues, including liver damage, hypertension, diabetes, cardiovascular disease, GI discomfort, and much more. Symptoms of these health conditions can involve inflammation and pain, adding to our chronic pain. 

As we can see, alcohol contributes to chronic pain in many ways. So, can we still drink?

Can You Drink Alcohol With Chronic Pain?

Drinking alcohol with chronic pain isn’t recommended. Not only can it worsen chronic pain, but it also can create a cycle of dependence. 

Let’s say we’re sick and tired of the constant pain, and we decide to have a drink to take the edge off. It might numb the pain temporarily, but at a cost. When we drink, our brain releases serotonin and dopamine (our brain’s “feel good” hormones), which help us relax in the moment and feel a sense of pleasure. Alcohol can also help us relax physiologically by slowing down our heartbeat and releasing tension in our muscles (again, temporarily). These things alone can take over our brain’s reward system and drive us to come back for more.

When we add pain relief to that, our desire to drink can increase, heightening our risk of dependence. In this way, the consequences of drinking with chronic pain become greater, and our goal — relieving our pain — becomes all the more remote.

Alcohol not only worsens chronic pain but also leads to many other health issues. So, if alcohol isn’t a viable solution for pain relief, what is?

Tips for Living Pain-Free

There is no current cure for chronic pain,but making positive lifestyle changes can help manage it. Here are several strategies to consider:

  • Gentle exercise. Gentle stretching or low-impact movement such as walking, yoga, and Pilates increases blood flow and produces endorphins, which promote overall well-being without putting too much stress on our body and lead to more pain. 
  • Anti-inflammatory diet. Nutrition plays a key role in healing and reducing inflammation. Eat a diet rich in fruits, vegetables, whole grains, and healthy fats. 
  • Sleep aids. Sleep is essential for healing and reducing stress. But pain can impact our sleep, creating a vicious cycle where we lack rest and have more pain. Try sleep aids such as magnesium, melatonin, and even meditation to get a more well-rested night of sleep.
  • Stress management. Managing stress can help relieve pain. Try disconnecting from social media, spending time in nature, journaling, or exploring hobbies.
  • Alternative treatments. Holistic treatments such as acupuncture, cryotherapy, and red light therapy have also been found to reduce pain by addressing different facets of our health. 
  • Community support. Engaging with others who may be going through a similar experience, venting with those who can empathize, and getting professional advice can help us navigate the journey to better health with a sense of connection and empowerment. 

A life with less pain is within reach when we make these positive lifestyle changes! On top of that, our overall health will improve so we can enjoy a better quality of life.

Key Takeaways

While alcohol might offer temporary pain relief, its long-term effects often exacerbate the problem, leading to a cycle of increased pain and reliance that’s difficult to break. Now that we understand the major role that alcohol can play in chronic pain, we can implement healthier, more sustainable ways to manage it. We can break free from this cycle and work towards a pain-free life by quitting or cutting back on alcohol.

Alcohol and Health
2024-10-05 9:00
Alcohol and Health
Breaking Down the Health Risks of Occasional Binge Drinking
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An occasional binge drinking session might not seem like a huge deal, but science says it can damage our health. Find out the details in our latest blog!

20 min read

Stop Binge Drinking With Reframe!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet hundreds of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!

Read Full Article  →

What does chugging several pints of beer at a frat party, downing five margaritas at a resort, and finishing off a bottle of wine over the course of dinner have in common? They’re all examples of binge drinking. While the first one might seem to be the most obvious danger, all three pose risks — even if they occur occasionally.

Understanding Binge Drinking: What Sets It Apart

A man grips a glass of whiskey

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) defines binge drinking as consuming a large amount of alcohol in a short amount of time — usually large enough to raise our blood alcohol concentration (BAC) to 0.08% or more. It usually means drinking five or more drinks for men or four or more for women within about two hours. 

And while no amount of alcohol does our health any good, binge drinking takes a particularly heavy toll. For a deep dive, check out “Binge Drinking: Definition, Effects, and How To Stop.” For now, here’s the gist:

  • Binge drinking increases the risk of alcohol-related injuries and accidents. Drinking large amounts of alcohol increases the chances of blackouts and alcohol poisoning — some of the most dangerous effects. It also puts us at risk of falls and other injuries, especially if we end up driving under the influence. According to the CDC, binge drinking contributed to at least a third of around 178,000 alcohol-related deaths between 2020 and 2021. 
  • Over time, it takes a toll on the body. Alcohol — especially in excessive amounts — wreaks havoc on the body. From the liver, heart, and brain to our muscles, bones, and lungs, virtually no system is left unaffected.
  • It can lead to alcohol dependence. While binge drinking itself isn’t necessarily a symptom of AUD, it’s a clear sign that we might be on our way to developing dependence. Given alcohol’s effects on the body and brain, it’s only a matter of time that regular bouts of binge drinking will put us at risk of falling deeper into the alcohol trap.

All in all, binge drinking is asking for trouble. But, you might be thinking, what if it’s not a regular thing? Is doing it once in a while really that big of a deal?

Occasional Binge Drinking: Know the Risks

What are the risks of an occasional drinking binge? Let’s take a closer look to find out!

1. The Liver’s Struggle

When it comes to binge drinking (even on occasion), the liver bears the brunt of the burden. As the body’s main detox organ, it’s at the front lines of processing alcohol and getting it out of the body. The process involves two steps, one of which produces a toxic byproduct known as acetaldehyde. Eliminating these toxins is taxing for the liver, especially if it gets overloaded. Because it can only process one drink per hour, giving it more than it can handle spells trouble. Here’s what happens in more detail:

  • Inflammation and liver damage. Binge drinking triggers inflammation in the liver. Studies show that even occasional binge drinking triggers early-stage liver disease and inflammation while increasing the levels of enzymes that help metabolize alcohol. The elevated enzyme levels, in turn, are tell-tale signs of trouble: their activity is known to trigger oxidative damage, and harm the liver. 
  • Fatty liver disease. Fatty liver disease is often seen in chronic heavy drinkers, but studies have shown that even a single binge drinking episode can temporarily increase fat accumulation in the liver. The same amount of alcohol consumed over a longer stretch of time didn’t lead to the same results (though we shouldn’t see this as a green light to keep drinking, for other reasons). 

The most alarming part? Liver damage often doesn’t have obvious signs, so we might not know this vital organ is having trouble.

2. Digestive System Disruption

Alcohol wreaks havoc on our digestive system, and even occasional binge drinking takes a toll. Studies show that even one bout of binge drinking causes “leaky gut.” And our gut is the last place we want to have a leak: the condition causes toxins to seep out of the digestive tract into the bloodstream.

Another study found similar effects. When participants were given enough booze to raise their BAC to 0.08%, their blood work showed that the “binge for science” resulted in a rise in toxin levels. There were also signs of bacterial DNA, indicating that bacteria seeped out of the gut. Yikes!

As NIAAA director George Koob explains, “While the negative health effects of chronic drinking are well-documented, this is a key study to show that a single alcohol binge can cause damaging effects such as bacterial leakage from the gut into the bloodstream.”

3. Immune System Under Attack

Wake up with a scratchy throat the morning after a night that got a bit too rowdy? It might be more than just all that loud karaoke singing at the bar. Alcohol is known to make us more vulnerable to infections, and science says that even a single bout of binge drinking takes a toll on our immune system. Research shows that it sets us at higher risk of infections for up to 24 hours!

4. Sleep Disruption

A night of heavy drinking might leave us deep in slumber at the end (hopefully in our own bed). But while the depressant effects cause the initial drowsiness, alcohol wreaks havoc on our sleep patterns, robbing us of the most restorative REM stages and leading to frequent awakenings during the second half of the night.

Another unpleasant surprise? Research shows that a single episode of binge drinking also disrupts our sleep — in a way that might have long term consequences. A team of scientists monitored the sleep patterns of mice that got “drunk for science” to test the effects of drinking. On the surface, the experience was one many of us can relate to: the mice crashed right into deep sleep (skipping the REM stage) and were in for a rude awakening in the second half of the sleep period. However, digging deeper revealed that the single binge drinking episode induced changes in the expression of a gene coding for adenosine, a sleep-promoting chemical. That’s right — a single night of revelry can actually rewrite our genes! The good news is that most damage from alcohol is reversible, as long as we quit drinking and take care of our health.

5. Heart Health Under Threat

It might be known as “holiday heart syndrome,” but this unfortunate fallout of binge drinking looms large any day of the year when we choose to overindulge — and it’s nothing to celebrate. The term refers to a form of arrhythmia — a disruption in the electrical signaling of the heart that causes it to beat unevenly.

And even occasional binge drinking can bring it on! Research shows that the potentially dangerous arrhythmia can happen in people who don’t drink on a regular basis but go all out the few times that they do choose to partake.

6. Pancreas Problems

The pancreas — an organ that plays an important role in digestion and blood sugar regulation — is another potential target for alcohol’s nefarious effects. However, it’s not just frequent alcohol use that puts us in danger! 

Research shows that binge drinking can lead to acute pancreatitis — a sudden inflammation of the pancreas that can be triggered by a single night of overindulgence. The risk is especially high for women: scientists have determined that going over the threshold of 40 grams of alcohol in one day (or roughly 3 standard drinks) puts women in serious danger of pancreatitis.

7. Risk of Blackouts, Overdose, and Injuries

We never think it’ll happen to us, but the stats are sobering: according to the NIAAA, alcohol-related emergency room visits have been on the rise, with an average increase of 210,000 cases per year. And while not all are related to binge drinking, consuming a lot of alcohol at once — even on occasion — puts us at greater risk of overdose and various injuries.

Many of these injuries occur when we get drunk quickly, not realizing how impaired we’ve become. In addition to alcohol overdose (or alcohol poisoning), we’re putting ourselves at serious risk of accidents and injuries. Many occur on the road. Here’s how the NHTSA puts it

“Every day, about 37 people in the United States die in drunk-driving crashes — that's one person every 39 minutes. In 2022, 13,524 people died in alcohol-impaired driving traffic deaths. These deaths were all preventable.”

In addition to losing our coordination and judgment, we might not even remember what happened. As a result, getting “blackout drunk” is one of the most alarming risks associated with binge drinking. While we might look “functional” (maybe even functional enough to drive), we’re actually very intoxicated and not aware of our actions. And because alcohol interferes with the hippocampus — the memory center of the brain — we might not have any memories that led to the aftermath we’re faced with the next day.

8. Risk of Addiction

Over time, even occasional binge drinking puts us at risk of developing alcohol dependence. The shifts in neurochemistry triggered by booze lead to a higher tolerance: it takes more alcohol to achieve the same effects. As a result, we might find that our binges get larger and more frequent, especially if we start associating binge drinking with relaxation or “letting loose.” The powerful flood of dopamine might tempt us to repeat the binge, leading to increased cravings and eventually causing alcohol dependence to set in.

For example, what starts as a monthly pub crawl tradition with a group of friends might turn into weekly binge drinking. Before we know it, the weekends are starting on Thursdays and we’re finding more and more “reasons” to pick up the glass. While initially binge drinking was a “social thing,” it starts becoming the go-to “solution” for dealing with anything life throws our way.

Tips To Stop Binge Drinking

Now that we see why binge drinking — even on occasion — isn’t the way to go, what can we do about it? It’s all about reframing our mindset and planning ahead.

  • Rethink the drink. First things first: if binge drinking has become a problem, consider cutting back or taking a break. Approach the situation in the spirit of curiosity rather than deprivation: what if letting booze go could lead to a number of positive outcomes? (Want to feel inspired? Check out “10 Benefits of an Alcohol-Free Lifestyle.”)
  • Set your limits. If you do drink, decide ahead of time how much you’ll have. Tell an accountability buddy about your plans for an extra buffer of protection.
  • Know your triggers. If you tend to binge drink on particular days (for example, on the weekend), at certain parties (Oktoberfest, Saint Patrick’s Day, and New Year’s are the obvious contenders, but there could be others), or with a certain crowd, have a plan in place. Keep someone you trust in the loop, have an exit strategy, and check out “Identifying and Managing Triggers That Lead to Unhealthy Drinking Habits.”
  • Reframe the holidays. If holidays are a big binge drinking trigger, spend some time planning a healthier celebration. Take a look at “How to Avoid Holiday Binge Drinking” for ideas.

Want to learn more? Check out “How To Stop Binge Drinking: A Science-Backed Approach.” And remember, Reframe is here to help you every step of the way!

Tips To Stop Binge Drinking

Summing Up

There’s nothing good about binge drinking, and if we do choose to drink, we should space out our drinks to give our liver adequate time to process the alcohol. The best way to keep our liver safe, however, is to avoid drinking altogether!

What does chugging several pints of beer at a frat party, downing five margaritas at a resort, and finishing off a bottle of wine over the course of dinner have in common? They’re all examples of binge drinking. While the first one might seem to be the most obvious danger, all three pose risks — even if they occur occasionally.

Understanding Binge Drinking: What Sets It Apart

A man grips a glass of whiskey

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) defines binge drinking as consuming a large amount of alcohol in a short amount of time — usually large enough to raise our blood alcohol concentration (BAC) to 0.08% or more. It usually means drinking five or more drinks for men or four or more for women within about two hours. 

And while no amount of alcohol does our health any good, binge drinking takes a particularly heavy toll. For a deep dive, check out “Binge Drinking: Definition, Effects, and How To Stop.” For now, here’s the gist:

  • Binge drinking increases the risk of alcohol-related injuries and accidents. Drinking large amounts of alcohol increases the chances of blackouts and alcohol poisoning — some of the most dangerous effects. It also puts us at risk of falls and other injuries, especially if we end up driving under the influence. According to the CDC, binge drinking contributed to at least a third of around 178,000 alcohol-related deaths between 2020 and 2021. 
  • Over time, it takes a toll on the body. Alcohol — especially in excessive amounts — wreaks havoc on the body. From the liver, heart, and brain to our muscles, bones, and lungs, virtually no system is left unaffected.
  • It can lead to alcohol dependence. While binge drinking itself isn’t necessarily a symptom of AUD, it’s a clear sign that we might be on our way to developing dependence. Given alcohol’s effects on the body and brain, it’s only a matter of time that regular bouts of binge drinking will put us at risk of falling deeper into the alcohol trap.

All in all, binge drinking is asking for trouble. But, you might be thinking, what if it’s not a regular thing? Is doing it once in a while really that big of a deal?

Occasional Binge Drinking: Know the Risks

What are the risks of an occasional drinking binge? Let’s take a closer look to find out!

1. The Liver’s Struggle

When it comes to binge drinking (even on occasion), the liver bears the brunt of the burden. As the body’s main detox organ, it’s at the front lines of processing alcohol and getting it out of the body. The process involves two steps, one of which produces a toxic byproduct known as acetaldehyde. Eliminating these toxins is taxing for the liver, especially if it gets overloaded. Because it can only process one drink per hour, giving it more than it can handle spells trouble. Here’s what happens in more detail:

  • Inflammation and liver damage. Binge drinking triggers inflammation in the liver. Studies show that even occasional binge drinking triggers early-stage liver disease and inflammation while increasing the levels of enzymes that help metabolize alcohol. The elevated enzyme levels, in turn, are tell-tale signs of trouble: their activity is known to trigger oxidative damage, and harm the liver. 
  • Fatty liver disease. Fatty liver disease is often seen in chronic heavy drinkers, but studies have shown that even a single binge drinking episode can temporarily increase fat accumulation in the liver. The same amount of alcohol consumed over a longer stretch of time didn’t lead to the same results (though we shouldn’t see this as a green light to keep drinking, for other reasons). 

The most alarming part? Liver damage often doesn’t have obvious signs, so we might not know this vital organ is having trouble.

2. Digestive System Disruption

Alcohol wreaks havoc on our digestive system, and even occasional binge drinking takes a toll. Studies show that even one bout of binge drinking causes “leaky gut.” And our gut is the last place we want to have a leak: the condition causes toxins to seep out of the digestive tract into the bloodstream.

Another study found similar effects. When participants were given enough booze to raise their BAC to 0.08%, their blood work showed that the “binge for science” resulted in a rise in toxin levels. There were also signs of bacterial DNA, indicating that bacteria seeped out of the gut. Yikes!

As NIAAA director George Koob explains, “While the negative health effects of chronic drinking are well-documented, this is a key study to show that a single alcohol binge can cause damaging effects such as bacterial leakage from the gut into the bloodstream.”

3. Immune System Under Attack

Wake up with a scratchy throat the morning after a night that got a bit too rowdy? It might be more than just all that loud karaoke singing at the bar. Alcohol is known to make us more vulnerable to infections, and science says that even a single bout of binge drinking takes a toll on our immune system. Research shows that it sets us at higher risk of infections for up to 24 hours!

4. Sleep Disruption

A night of heavy drinking might leave us deep in slumber at the end (hopefully in our own bed). But while the depressant effects cause the initial drowsiness, alcohol wreaks havoc on our sleep patterns, robbing us of the most restorative REM stages and leading to frequent awakenings during the second half of the night.

Another unpleasant surprise? Research shows that a single episode of binge drinking also disrupts our sleep — in a way that might have long term consequences. A team of scientists monitored the sleep patterns of mice that got “drunk for science” to test the effects of drinking. On the surface, the experience was one many of us can relate to: the mice crashed right into deep sleep (skipping the REM stage) and were in for a rude awakening in the second half of the sleep period. However, digging deeper revealed that the single binge drinking episode induced changes in the expression of a gene coding for adenosine, a sleep-promoting chemical. That’s right — a single night of revelry can actually rewrite our genes! The good news is that most damage from alcohol is reversible, as long as we quit drinking and take care of our health.

5. Heart Health Under Threat

It might be known as “holiday heart syndrome,” but this unfortunate fallout of binge drinking looms large any day of the year when we choose to overindulge — and it’s nothing to celebrate. The term refers to a form of arrhythmia — a disruption in the electrical signaling of the heart that causes it to beat unevenly.

And even occasional binge drinking can bring it on! Research shows that the potentially dangerous arrhythmia can happen in people who don’t drink on a regular basis but go all out the few times that they do choose to partake.

6. Pancreas Problems

The pancreas — an organ that plays an important role in digestion and blood sugar regulation — is another potential target for alcohol’s nefarious effects. However, it’s not just frequent alcohol use that puts us in danger! 

Research shows that binge drinking can lead to acute pancreatitis — a sudden inflammation of the pancreas that can be triggered by a single night of overindulgence. The risk is especially high for women: scientists have determined that going over the threshold of 40 grams of alcohol in one day (or roughly 3 standard drinks) puts women in serious danger of pancreatitis.

7. Risk of Blackouts, Overdose, and Injuries

We never think it’ll happen to us, but the stats are sobering: according to the NIAAA, alcohol-related emergency room visits have been on the rise, with an average increase of 210,000 cases per year. And while not all are related to binge drinking, consuming a lot of alcohol at once — even on occasion — puts us at greater risk of overdose and various injuries.

Many of these injuries occur when we get drunk quickly, not realizing how impaired we’ve become. In addition to alcohol overdose (or alcohol poisoning), we’re putting ourselves at serious risk of accidents and injuries. Many occur on the road. Here’s how the NHTSA puts it

“Every day, about 37 people in the United States die in drunk-driving crashes — that's one person every 39 minutes. In 2022, 13,524 people died in alcohol-impaired driving traffic deaths. These deaths were all preventable.”

In addition to losing our coordination and judgment, we might not even remember what happened. As a result, getting “blackout drunk” is one of the most alarming risks associated with binge drinking. While we might look “functional” (maybe even functional enough to drive), we’re actually very intoxicated and not aware of our actions. And because alcohol interferes with the hippocampus — the memory center of the brain — we might not have any memories that led to the aftermath we’re faced with the next day.

8. Risk of Addiction

Over time, even occasional binge drinking puts us at risk of developing alcohol dependence. The shifts in neurochemistry triggered by booze lead to a higher tolerance: it takes more alcohol to achieve the same effects. As a result, we might find that our binges get larger and more frequent, especially if we start associating binge drinking with relaxation or “letting loose.” The powerful flood of dopamine might tempt us to repeat the binge, leading to increased cravings and eventually causing alcohol dependence to set in.

For example, what starts as a monthly pub crawl tradition with a group of friends might turn into weekly binge drinking. Before we know it, the weekends are starting on Thursdays and we’re finding more and more “reasons” to pick up the glass. While initially binge drinking was a “social thing,” it starts becoming the go-to “solution” for dealing with anything life throws our way.

Tips To Stop Binge Drinking

Now that we see why binge drinking — even on occasion — isn’t the way to go, what can we do about it? It’s all about reframing our mindset and planning ahead.

  • Rethink the drink. First things first: if binge drinking has become a problem, consider cutting back or taking a break. Approach the situation in the spirit of curiosity rather than deprivation: what if letting booze go could lead to a number of positive outcomes? (Want to feel inspired? Check out “10 Benefits of an Alcohol-Free Lifestyle.”)
  • Set your limits. If you do drink, decide ahead of time how much you’ll have. Tell an accountability buddy about your plans for an extra buffer of protection.
  • Know your triggers. If you tend to binge drink on particular days (for example, on the weekend), at certain parties (Oktoberfest, Saint Patrick’s Day, and New Year’s are the obvious contenders, but there could be others), or with a certain crowd, have a plan in place. Keep someone you trust in the loop, have an exit strategy, and check out “Identifying and Managing Triggers That Lead to Unhealthy Drinking Habits.”
  • Reframe the holidays. If holidays are a big binge drinking trigger, spend some time planning a healthier celebration. Take a look at “How to Avoid Holiday Binge Drinking” for ideas.

Want to learn more? Check out “How To Stop Binge Drinking: A Science-Backed Approach.” And remember, Reframe is here to help you every step of the way!

Tips To Stop Binge Drinking

Summing Up

There’s nothing good about binge drinking, and if we do choose to drink, we should space out our drinks to give our liver adequate time to process the alcohol. The best way to keep our liver safe, however, is to avoid drinking altogether!

Alcohol and Health
2024-10-05 9:00
Alcohol and Health
What Is Auto-Brewery Syndrome?
This is some text inside of a div block.

Auto-brewery syndrome is a condition that causes intoxication without alcohol. Check out our latest blog for more info on what it entails and the dangers associated.

16 min read

Manage Your Alcohol Intake With Reframe!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet hundreds of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!

Read Full Article  →

A Belgian man was recently charged with a DUI and then later acquitted after claiming that he didn’t drink a drop of alcohol even though his BAC showed otherwise. Is it possible to become intoxicated without drinking any alcohol? 

While this isn’t the case for most of us, those who are diagnosed with auto-brewery syndrome do experience this phenomenon. To get a better idea of how this condition can be dangerous with or without consuming alcohol, let’s first understand what auto-brewery syndrome is.

What Is Auto-Brewery Syndrome?

A man sleeps on a couch beside a bottle of alcohol and a glass of whiskey

Auto-brewery syndrome is a rare condition that is also known as gut fermentation syndrome. It’s characterized by the overgrowth of certain bacteria and fungi in our gut that can turn carbohydrates into alcohol.

While we all have healthy fungi and bacteria that live in our gut microbiome, overgrowth of these bacteria can lead to issues such as auto-brewery syndrome. 

The overgrowth of yeast feeds on sugars that we consume and converts them into energy, producing carbon dioxide and ethanol as byproducts. Ethanol, the intoxicating component of alcohol, enters our bloodstream and travels throughout our body causing symptoms of intoxication. This means that our blood alcohol concentration (BAC) can be elevated without consuming any alcohol and significantly elevated with minimal amounts of alcohol. How did we figure this out?

The History of Gut Fermentation Syndrome

One of the earliest cases of gut fermentation syndrome was documented in 1948. A five-year-old African boy had passed away after swelling in his GI tract caused his stomach to rupture. When his body was examined postmortem, it was noted that the gas and liquid found in his abdominal cavity smelled like alcohol. 

Other early cases were documented in Japan dating back to the 1950s. In 1976, researchers documented a case of a 24-year-old woman who became intoxicated after consuming carbohydrates. Her condition was a result of an overgrowth of fungi, and she was prescribed antifungals while restricting her carbohydrate intake. This resolved her symptoms and paved the way for what we know now about auto-brewery syndrome. 


Less than 100 cases are reported worldwide; however, researchers believe the condition is underdiagnosed. To determine how auto-brewery syndrome is diagnosed, let’s first understand why it happens.

What Causes Auto-Brewery Syndrome?

Since auto-brewery syndrome is caused by an imbalance of our gut microbiome, several underlying conditions, GI disease, and habits that damage our gut microbiome can lead to the development of the condition. A specific type of yeast, saccharomyces cerevisiae, is commonly found at abnormal levels in patients with auto-brewery syndrome. 

Stemming from gut microbiome imbalance, other conditions can also contribute to the risk of developing auto-brewery syndrome:

  • Crohn’s disease
  • Irritable bowel syndrome
  • Small intestinal bacterial overgrowth 
  • Diabetes 
  • Obesity 
  • Weakened immune system 

Habits that impact our gut microbiome can also increase the risk of auto-brewery syndrome. Excessive and continuous antibiotic use destroys healthy bacteria in our gut. This significantly disrupts our gut microbiome, which can contribute to the overgrowth of bacteria and fungi. A poor diet high in carbohydrates or processed foods can also cause GI distress and imbalances in our gut microbiome. 

Now that we understand what can cause auto-brewery syndrome, let’s take a look at the symptoms.

How Auto-Brewery Syndrome Is Treated

Auto-Brewery Syndrome Symptoms

As the name suggests, auto-brewery syndrome means our body produces alcohol inside from within. This explains the symptoms of the condition, which are synonymous with alcohol intoxication and hangover symptoms. 

The initial symptoms of auto-brewery syndrome mimic alcohol intoxication:

  • Loss of coordination
  • Brain fog 
  • Dizziness 
  • Slurred speech
  • Mood changes 
  • Delirium

Once our body metabolizes the alcohol produced by auto-brewery syndrome, we may feel symptoms synonymous with an alcohol hangover:

  • Headaches
  • Fatigue
  • Bloating
  • Burping
  • Nausea and vomiting
  • Difficulty concentrating
  • Memory issues

Symptoms of auto-brewery may subside once our body detoxes the alcohol. If not addressed, symptoms can continue when we consume carbohydrates and sugars. If we experience symptoms of auto-brewery syndrome, how can we be sure it’s not something else?

How To Diagnose Auto-Brewery Syndrome

Auto-brewery syndrome is diagnosed by a physician using a combination of laboratory and observational tests. Since it’s such a rare condition, most physicians will run tests to rule out other common illnesses first.

Preliminary measures, such as reviewing medical history, documenting current symptoms, and completing a physical exam can give our physician a better idea of what may be going on. Blood and urine tests can help rule out underlying conditions. Additional tests such as stool samples and endoscopies may be ordered to check for bacterial or fungal overgrowth. 

Once everything else is ruled out, we may undergo a carbohydrate challenge test. This test consists of consuming a carbohydrate-rich meal or glucose pills on an empty stomach and then measuring our BAC. An elevated BAC without drinking alcohol would indicate auto-brewery syndrome. And if our body is producing alcohol on its own, we might want to think twice about drinking alcohol.

Can You Drink With Auto-Brewery Syndrome?

Since patients with auto-brewery syndrome convert carbohydrates and sugar, producing alcohol on its own, drinking alcohol can be extremely dangerous. Our BAC may be significantly elevated compared to those without the condition. High BAC can lead to dangerous symptoms of intoxication and cause greater long-term health effects. 

Even after auto-brewery syndrome is treated with antifungals, symptoms can often recur. Since alcohol is a substance that disrupts our gut microbiome, drinking alcohol after initial treatment can increase the risk of yeast overgrowth and symptoms of auto-brewery syndrome. Alcohol also puts a damper on our immune system, which plays a major role in protecting our body from harm by keeping harmful bacteria and fungi at bay. 

Although our body producing alcohol from carbohydrates and sugars may not seem like such a bad thing, it can be dangerous and difficult to manage. Can you imagine getting drunk from eating a donut? This is just one of many ways auto-brewery syndrome can interfere with our daily life. Let’s explore some other consequences of the condition.

Dangers of Auto-Brewery Syndrome

Auto-brewery can be extremely dangerous, especially when not understood or diagnosed. Alcohol has dangerous effects but usually, we’re making a conscious decision to drink. For those of us with auto-brewery syndrome, we can get intoxicated just from eating a meal with carbs. Synonymous with consuming alcohol, intoxication from auto-brewery syndrome can have many dangers:

  • Increased risk of accidents
  • Alcohol poisoning
  • Increased risk of participating in risky behavior
  • Decreased motor control 
  • Impaired judgment 

Alcohol produced by auto-brewery syndrome is also associated with the same long-term health conditions as consuming alcohol:

  • Liver damage or disease 
  • Cardiovascular disease
  • Certain types of cancer
  • Diabetes
  • GI issues

Even though we may not be consuming alcohol, the ethanol produced by auto-brewery syndrome can lead to cravings and dependence on alcohol. Auto-brewery syndrome can also be associated with legal implications and affect our academic or employment performance. We may not have consumed a drop of alcohol, but our BAC may show otherwise. This can lead to termination from employment, fines for underage drinking, and charges for driving under the influence (DUI) which has happened recently. That being said, the condition can be treated.

Treating Auto-Brewery Syndrome

Treatment for auto-brewery syndrome often includes a combination of lifestyle changes and medication. Lifestyle changes consist of making dietary adjustments that include the following:

  • Avoiding carbohydrates 
  • Avoiding processed foods 
  • Avoiding added sugars
  • Eating a higher-protein diet for satiety

Since auto-brewery syndrome is caused by fungi overgrowth, antifungals (and sometimes antibiotics) are used to treat the condition. Specifically, medications used to treat yeast infections in the gut are commonly used:

  • Fluconazole
  • Itraconazole
  • Nystatin
  • Echinocandins 

Sometimes, probiotic supplements are recommended to help balance the gut microbiome. However, since the condition is not fully understood, individual recommendations may vary. Even after treating auto-brewery syndrome, it can reoccur. For those of us with chronic auto-brewery syndrome, long-term management may be needed.

Managing Auto-Brewery Syndrome

Making long-term lifestyle changes can help prevent auto-brewery syndrome from coming back. Here are some ways we can better manage auto-brewery syndrome:

  • Treat underlying conditions. Many underlying conditions can contribute to imbalances in our gut microbiome — increasing the risk of auto-brewery syndrome. By managing related underlying conditions, we can minimize the risk of recurrence of auto-brewery syndrome. 
  • Exercise regularly. Research shows that exercise can help with maintaining a healthy gut microbiome. It also has positive effects on our immune system, helping balance bacteria and fight off infections.
  • Limit food and drinks with added sugar. Excessive consumption of sugars can disrupt the gut microbiome. It also increases the risk of obesity and diabetes, which are both associated with an increased risk of auto-brewery syndrome.
  • Choose complex carbohydrates. Complex carbohydrates take longer to break down — limiting drastic spikes in our blood sugar. This can help us maintain a healthy gut microbiome and prevent severe blood alcohol increases when auto-brewery syndrome is present. Try complex carbs from whole grains and vegetables such as oats and potatoes rather than simple carbs from processed foods like candy and pastries.
  • Quit/cut back on alcohol. Alcohol can feed the overgrowth of yeast — elongating the presence of the condition. It can also negatively affect our gut microbiome, increasing the risk of recurrence. 

Even though alcohol isn’t always a part of auto-brewery syndrome, it can further complicate the issue. Additionally, if untreated, auto-brewery syndrome can cause alcohol dependence — exponentially adding to the dangers.

Key Takeaways

Auto-brewery syndrome, although extremely rare, is like drinking alcohol without consuming any alcohol. Just as alcohol is produced through yeast fermentation, an overgrowth of yeast in our gut reproduces the same process inside our body. This can be extremely dangerous if left untreated. For those with auto-brewery syndrome, drinking can be exponentially dangerous. That said, quitting or cutting back on alcohol can be beneficial for all of us.

A Belgian man was recently charged with a DUI and then later acquitted after claiming that he didn’t drink a drop of alcohol even though his BAC showed otherwise. Is it possible to become intoxicated without drinking any alcohol? 

While this isn’t the case for most of us, those who are diagnosed with auto-brewery syndrome do experience this phenomenon. To get a better idea of how this condition can be dangerous with or without consuming alcohol, let’s first understand what auto-brewery syndrome is.

What Is Auto-Brewery Syndrome?

A man sleeps on a couch beside a bottle of alcohol and a glass of whiskey

Auto-brewery syndrome is a rare condition that is also known as gut fermentation syndrome. It’s characterized by the overgrowth of certain bacteria and fungi in our gut that can turn carbohydrates into alcohol.

While we all have healthy fungi and bacteria that live in our gut microbiome, overgrowth of these bacteria can lead to issues such as auto-brewery syndrome. 

The overgrowth of yeast feeds on sugars that we consume and converts them into energy, producing carbon dioxide and ethanol as byproducts. Ethanol, the intoxicating component of alcohol, enters our bloodstream and travels throughout our body causing symptoms of intoxication. This means that our blood alcohol concentration (BAC) can be elevated without consuming any alcohol and significantly elevated with minimal amounts of alcohol. How did we figure this out?

The History of Gut Fermentation Syndrome

One of the earliest cases of gut fermentation syndrome was documented in 1948. A five-year-old African boy had passed away after swelling in his GI tract caused his stomach to rupture. When his body was examined postmortem, it was noted that the gas and liquid found in his abdominal cavity smelled like alcohol. 

Other early cases were documented in Japan dating back to the 1950s. In 1976, researchers documented a case of a 24-year-old woman who became intoxicated after consuming carbohydrates. Her condition was a result of an overgrowth of fungi, and she was prescribed antifungals while restricting her carbohydrate intake. This resolved her symptoms and paved the way for what we know now about auto-brewery syndrome. 


Less than 100 cases are reported worldwide; however, researchers believe the condition is underdiagnosed. To determine how auto-brewery syndrome is diagnosed, let’s first understand why it happens.

What Causes Auto-Brewery Syndrome?

Since auto-brewery syndrome is caused by an imbalance of our gut microbiome, several underlying conditions, GI disease, and habits that damage our gut microbiome can lead to the development of the condition. A specific type of yeast, saccharomyces cerevisiae, is commonly found at abnormal levels in patients with auto-brewery syndrome. 

Stemming from gut microbiome imbalance, other conditions can also contribute to the risk of developing auto-brewery syndrome:

  • Crohn’s disease
  • Irritable bowel syndrome
  • Small intestinal bacterial overgrowth 
  • Diabetes 
  • Obesity 
  • Weakened immune system 

Habits that impact our gut microbiome can also increase the risk of auto-brewery syndrome. Excessive and continuous antibiotic use destroys healthy bacteria in our gut. This significantly disrupts our gut microbiome, which can contribute to the overgrowth of bacteria and fungi. A poor diet high in carbohydrates or processed foods can also cause GI distress and imbalances in our gut microbiome. 

Now that we understand what can cause auto-brewery syndrome, let’s take a look at the symptoms.

How Auto-Brewery Syndrome Is Treated

Auto-Brewery Syndrome Symptoms

As the name suggests, auto-brewery syndrome means our body produces alcohol inside from within. This explains the symptoms of the condition, which are synonymous with alcohol intoxication and hangover symptoms. 

The initial symptoms of auto-brewery syndrome mimic alcohol intoxication:

  • Loss of coordination
  • Brain fog 
  • Dizziness 
  • Slurred speech
  • Mood changes 
  • Delirium

Once our body metabolizes the alcohol produced by auto-brewery syndrome, we may feel symptoms synonymous with an alcohol hangover:

  • Headaches
  • Fatigue
  • Bloating
  • Burping
  • Nausea and vomiting
  • Difficulty concentrating
  • Memory issues

Symptoms of auto-brewery may subside once our body detoxes the alcohol. If not addressed, symptoms can continue when we consume carbohydrates and sugars. If we experience symptoms of auto-brewery syndrome, how can we be sure it’s not something else?

How To Diagnose Auto-Brewery Syndrome

Auto-brewery syndrome is diagnosed by a physician using a combination of laboratory and observational tests. Since it’s such a rare condition, most physicians will run tests to rule out other common illnesses first.

Preliminary measures, such as reviewing medical history, documenting current symptoms, and completing a physical exam can give our physician a better idea of what may be going on. Blood and urine tests can help rule out underlying conditions. Additional tests such as stool samples and endoscopies may be ordered to check for bacterial or fungal overgrowth. 

Once everything else is ruled out, we may undergo a carbohydrate challenge test. This test consists of consuming a carbohydrate-rich meal or glucose pills on an empty stomach and then measuring our BAC. An elevated BAC without drinking alcohol would indicate auto-brewery syndrome. And if our body is producing alcohol on its own, we might want to think twice about drinking alcohol.

Can You Drink With Auto-Brewery Syndrome?

Since patients with auto-brewery syndrome convert carbohydrates and sugar, producing alcohol on its own, drinking alcohol can be extremely dangerous. Our BAC may be significantly elevated compared to those without the condition. High BAC can lead to dangerous symptoms of intoxication and cause greater long-term health effects. 

Even after auto-brewery syndrome is treated with antifungals, symptoms can often recur. Since alcohol is a substance that disrupts our gut microbiome, drinking alcohol after initial treatment can increase the risk of yeast overgrowth and symptoms of auto-brewery syndrome. Alcohol also puts a damper on our immune system, which plays a major role in protecting our body from harm by keeping harmful bacteria and fungi at bay. 

Although our body producing alcohol from carbohydrates and sugars may not seem like such a bad thing, it can be dangerous and difficult to manage. Can you imagine getting drunk from eating a donut? This is just one of many ways auto-brewery syndrome can interfere with our daily life. Let’s explore some other consequences of the condition.

Dangers of Auto-Brewery Syndrome

Auto-brewery can be extremely dangerous, especially when not understood or diagnosed. Alcohol has dangerous effects but usually, we’re making a conscious decision to drink. For those of us with auto-brewery syndrome, we can get intoxicated just from eating a meal with carbs. Synonymous with consuming alcohol, intoxication from auto-brewery syndrome can have many dangers:

  • Increased risk of accidents
  • Alcohol poisoning
  • Increased risk of participating in risky behavior
  • Decreased motor control 
  • Impaired judgment 

Alcohol produced by auto-brewery syndrome is also associated with the same long-term health conditions as consuming alcohol:

  • Liver damage or disease 
  • Cardiovascular disease
  • Certain types of cancer
  • Diabetes
  • GI issues

Even though we may not be consuming alcohol, the ethanol produced by auto-brewery syndrome can lead to cravings and dependence on alcohol. Auto-brewery syndrome can also be associated with legal implications and affect our academic or employment performance. We may not have consumed a drop of alcohol, but our BAC may show otherwise. This can lead to termination from employment, fines for underage drinking, and charges for driving under the influence (DUI) which has happened recently. That being said, the condition can be treated.

Treating Auto-Brewery Syndrome

Treatment for auto-brewery syndrome often includes a combination of lifestyle changes and medication. Lifestyle changes consist of making dietary adjustments that include the following:

  • Avoiding carbohydrates 
  • Avoiding processed foods 
  • Avoiding added sugars
  • Eating a higher-protein diet for satiety

Since auto-brewery syndrome is caused by fungi overgrowth, antifungals (and sometimes antibiotics) are used to treat the condition. Specifically, medications used to treat yeast infections in the gut are commonly used:

  • Fluconazole
  • Itraconazole
  • Nystatin
  • Echinocandins 

Sometimes, probiotic supplements are recommended to help balance the gut microbiome. However, since the condition is not fully understood, individual recommendations may vary. Even after treating auto-brewery syndrome, it can reoccur. For those of us with chronic auto-brewery syndrome, long-term management may be needed.

Managing Auto-Brewery Syndrome

Making long-term lifestyle changes can help prevent auto-brewery syndrome from coming back. Here are some ways we can better manage auto-brewery syndrome:

  • Treat underlying conditions. Many underlying conditions can contribute to imbalances in our gut microbiome — increasing the risk of auto-brewery syndrome. By managing related underlying conditions, we can minimize the risk of recurrence of auto-brewery syndrome. 
  • Exercise regularly. Research shows that exercise can help with maintaining a healthy gut microbiome. It also has positive effects on our immune system, helping balance bacteria and fight off infections.
  • Limit food and drinks with added sugar. Excessive consumption of sugars can disrupt the gut microbiome. It also increases the risk of obesity and diabetes, which are both associated with an increased risk of auto-brewery syndrome.
  • Choose complex carbohydrates. Complex carbohydrates take longer to break down — limiting drastic spikes in our blood sugar. This can help us maintain a healthy gut microbiome and prevent severe blood alcohol increases when auto-brewery syndrome is present. Try complex carbs from whole grains and vegetables such as oats and potatoes rather than simple carbs from processed foods like candy and pastries.
  • Quit/cut back on alcohol. Alcohol can feed the overgrowth of yeast — elongating the presence of the condition. It can also negatively affect our gut microbiome, increasing the risk of recurrence. 

Even though alcohol isn’t always a part of auto-brewery syndrome, it can further complicate the issue. Additionally, if untreated, auto-brewery syndrome can cause alcohol dependence — exponentially adding to the dangers.

Key Takeaways

Auto-brewery syndrome, although extremely rare, is like drinking alcohol without consuming any alcohol. Just as alcohol is produced through yeast fermentation, an overgrowth of yeast in our gut reproduces the same process inside our body. This can be extremely dangerous if left untreated. For those with auto-brewery syndrome, drinking can be exponentially dangerous. That said, quitting or cutting back on alcohol can be beneficial for all of us.

Alcohol and Health
2024-10-05 9:00
Alcohol and Health
Unique Risks of Drinking in the Air
This is some text inside of a div block.

Alcohol and flying is a common but potentially risky combination. Check out our latest blog for more about the unique risks of drinking before and while in the air.

15 min read

Practice Mindful Drinking With Reframe!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet hundreds of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol. 

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!

Read Full Article  →

Having a drink on a flight to calm the nerves or kick off the start of some much-needed time off is a common occurrence. However, with a recent rise in in-cabin incidents dubbed “air rage,” could alcohol be to blame? 

As it turns out, drinking alcohol in the air can affect us differently than it does on the ground. Let’s explore the unique risks of drinking in the air to help us decide whether skipping the drink on our next flight is the best move.

The History of Drinking Alcohol on Planes

A man takes a sip from a glass of wine

In 1914, the first commercial airline, the St. Petersburg-Tampa Airboat Line was introduced. However, it wasn’t until after the 1940s when Prohibition died down that alcohol was served in-flight. 

From the 1950s through the 1970s, known as the Golden Era of Flying, commercial flying took off. Throughout this time until the late 90s alcohol was served in-flight free of charge, much like the little packets of peanuts and pretzels we get today. It became an integral part of the luxurious flying experience.

Aside from the temporary pause in in-flight drink services during the COVID-19 pandemic due to mask mandates, alcohol continues to be a major component of in-flight services. Although alcoholic beverages are no longer free, they remain popular and have become intertwined with the in-air experience. 

Can You Take Alcohol on a Plane?

Airlines have strict policies for carry-on and checked luggage. However, as long as alcohol meets these requirements, including size restrictions and alcohol by volume (ABV), it can be brought onto the plane. Alcohol can even be purchased at duty-free stores in the airport, and drinks are offered or sold at airline terminals and lounges. 

Although we can bring our own alcohol onto the plane, we’re not allowed to drink it there. This is to prevent excessive drinking in-flight. All alcohol consumed in the cabin must be served by a flight attendant. While there’s no limit to the number of drinks that can be purchased, flight attendants are allowed to refuse to serve alcohol if a passenger appears to be intoxicated. With the recent in-flight incidents, are those of us who drink becoming more intoxicated while flying? Is that because alcohol affects us differently in the air?

Does Alcohol Affect You Differently at High Altitudes?

Anecdotal reports claim that drinking on a plane affects us differently than if we were to drink the same amount at ground level. However, research shows that altitude does not directly affect our blood alcohol concentration (BAC). So why might we feel different?

As it turns out, the conditions of a plane cabin and the high altitude can play major roles. At high elevations, there is less oxygen available, which is essential for normal bodily function. Although the plane cabin is pressurized to allow us to breathe at high altitudes, the oxygen levels available are lower than at ground level. 

Do You Get Drunk Faster on a Plane?

Many people report getting drunk faster or getting more drunk on a plane. However, although it may feel like it, alcohol doesn’t increase our BAC faster or higher on a plane. 

The specific conditions of a plane environment can impact our experience. Lower oxygen availability can cause symptoms such as increased heart rate, confusion, and disorientation — adding to the effects of alcohol intoxication. 

Alcohol also impacts our vestibular system, which controls our balance and coordination. The added movement of being in flight can further throw off our balance and motor coordination. These factors create the feeling of being more tipsy or drunk when drinking on a plane than under regular conditions.

Does Drinking Affect Health Outcomes Differently?


Ever feel more exhausted after traveling even though you’ve been sitting most of the time? Although we may not be doing much while we’re on a flight, the environment is a big adjustment for our body. Adding alcohol, a toxin, to the equation can cause even more stress.

Added stress can also impact our metabolization. The slower metabolization of alcohol means that the toxins linger in our body longer. This can increase the risk of harm that alcohol has on our cells and organs. While one drink may not make a significant difference, one drink on every flight (especially if we’re frequent fliers) can lead to an increased risk of alcohol-related health conditions. Does this mean we should completely avoid it?

Should You Drink While In the Air?

While drinking on a flight is quite prevalent, it’s associated with greater risks than drinking at ground level (although there’s already an extensive list of risks associated with drinking regularly). 

There are plenty of alternatives to help us relax if we’re nervous fliers. And there are plenty of other activities and non-alcoholic beverages that can kick off a vacation. 

How Much Is Too Much?

Since alcohol affects us all differently, there’s no set amount of alcohol that is deemed “safe” or “ok” for in-flight consumption. If we do decide to drink, it’s best to follow moderate consumption guidelines. 

Moderate drinking guidelines suggest no more than two drinks in a day for men and no more than one drink in a day for women. Since drinking in-flight can be associated with even greater risks, even moderate consumption can be associated with greater consequences than drinking regularly. Let’s get a better idea of the unique risks of drinking while in the air.

Risks of Drinking While in the Air 

Due to the specific environment of a plane cabin, drinking has additional risks in comparison to drinking on ground level:

  • Increased dehydration. The low humidity of the cabin air and the diuretic properties of alcohol can cause increased dehydration. 
  • Sleep disruptions. Flights can be draining, especially if we’re on a red-eye flight, and sleep is crucial. Alcohol can cause further sleep disruptions to what’s an already uncomfortable sleeping experience.
  • Worse hangovers. Drinking on planes is associated with worse hangovers due to the cabin environment. Increased dehydration and slowed alcohol metabolism can lead to a more unpleasant aftermath.
  • Increased motion sickness. Alcohol disrupts our vestibular system, which controls our balance. For those of us who are sensitive to motion sickness, drinking in-flight could make our symptoms worse. 
  • Behavior issues. Drinking lowers our inhibitions and impedes our judgment. Alcohol can also increase negative emotions such as frustration and anger, which can be aggravated due to the stress of flying on an airplane. Drinking problems have led to increased in-flight incidents including fights and unruly behavior.
  • Safety concerns. Since drinking impacts our inhibitions and judgment, we are more likely to engage in risky behaviors. This can lead to low adherence to safety regulations, such as keeping our seatbelts on or following emergency protocols.

The environment of a plane cabin can heighten the risks of alcohol. If we choose to drink, we can minimize the risks by practicing mindful drinking.

Risks of Drinking in the Air

Responsible Drinking Tips for Your Next Flight

Practicing mindful consumption while flying can help us prioritize our health and well-being while avoiding an unpleasant aftermath. We can implement strategies to practice responsible drinking while flying:

  • Set limits. The ease of ordering drink after drink can quickly get out of hand. Stick to one drink when choosing to consume alcohol in-flight. 
  • Stay hydrated. Drinking plenty of water and replenishing hydration with electrolytes can help combat dehydration from alcohol and the low humidity of the cabin air.
  • Choose alternatives. Airlines offer plenty of non-alcoholic options. Try mixing cranberry juice and soda water together to make a quick mocktail. We can also keep busy by reading a book or watching a movie. 
  • Maintain nutrition. Depending on the airline and flight, sometimes only snacks are provided. Bringing a meal or eating beforehand helps us avoid drinking on an empty stomach.

Excessive drinking anywhere can be detrimental to our health. Implementing these mindful drinking strategies on and off the plane can help us develop a more positive relationship with alcohol.

Touching Down

Drinking while flying is often associated with “just taking the edge off” or “kicking off the party early,” but it does more harm than good. Although being in the air doesn’t affect the actual potency of alcohol, the unique environment of a plane cabin adds to the risks of alcohol. Put on your favorite show and mix up a fun mocktail to prevent the heightened risks of drinking in the air. Say goodbye to feeling unwell by avoiding alcohol when you fly!

Having a drink on a flight to calm the nerves or kick off the start of some much-needed time off is a common occurrence. However, with a recent rise in in-cabin incidents dubbed “air rage,” could alcohol be to blame? 

As it turns out, drinking alcohol in the air can affect us differently than it does on the ground. Let’s explore the unique risks of drinking in the air to help us decide whether skipping the drink on our next flight is the best move.

The History of Drinking Alcohol on Planes

A man takes a sip from a glass of wine

In 1914, the first commercial airline, the St. Petersburg-Tampa Airboat Line was introduced. However, it wasn’t until after the 1940s when Prohibition died down that alcohol was served in-flight. 

From the 1950s through the 1970s, known as the Golden Era of Flying, commercial flying took off. Throughout this time until the late 90s alcohol was served in-flight free of charge, much like the little packets of peanuts and pretzels we get today. It became an integral part of the luxurious flying experience.

Aside from the temporary pause in in-flight drink services during the COVID-19 pandemic due to mask mandates, alcohol continues to be a major component of in-flight services. Although alcoholic beverages are no longer free, they remain popular and have become intertwined with the in-air experience. 

Can You Take Alcohol on a Plane?

Airlines have strict policies for carry-on and checked luggage. However, as long as alcohol meets these requirements, including size restrictions and alcohol by volume (ABV), it can be brought onto the plane. Alcohol can even be purchased at duty-free stores in the airport, and drinks are offered or sold at airline terminals and lounges. 

Although we can bring our own alcohol onto the plane, we’re not allowed to drink it there. This is to prevent excessive drinking in-flight. All alcohol consumed in the cabin must be served by a flight attendant. While there’s no limit to the number of drinks that can be purchased, flight attendants are allowed to refuse to serve alcohol if a passenger appears to be intoxicated. With the recent in-flight incidents, are those of us who drink becoming more intoxicated while flying? Is that because alcohol affects us differently in the air?

Does Alcohol Affect You Differently at High Altitudes?

Anecdotal reports claim that drinking on a plane affects us differently than if we were to drink the same amount at ground level. However, research shows that altitude does not directly affect our blood alcohol concentration (BAC). So why might we feel different?

As it turns out, the conditions of a plane cabin and the high altitude can play major roles. At high elevations, there is less oxygen available, which is essential for normal bodily function. Although the plane cabin is pressurized to allow us to breathe at high altitudes, the oxygen levels available are lower than at ground level. 

Do You Get Drunk Faster on a Plane?

Many people report getting drunk faster or getting more drunk on a plane. However, although it may feel like it, alcohol doesn’t increase our BAC faster or higher on a plane. 

The specific conditions of a plane environment can impact our experience. Lower oxygen availability can cause symptoms such as increased heart rate, confusion, and disorientation — adding to the effects of alcohol intoxication. 

Alcohol also impacts our vestibular system, which controls our balance and coordination. The added movement of being in flight can further throw off our balance and motor coordination. These factors create the feeling of being more tipsy or drunk when drinking on a plane than under regular conditions.

Does Drinking Affect Health Outcomes Differently?


Ever feel more exhausted after traveling even though you’ve been sitting most of the time? Although we may not be doing much while we’re on a flight, the environment is a big adjustment for our body. Adding alcohol, a toxin, to the equation can cause even more stress.

Added stress can also impact our metabolization. The slower metabolization of alcohol means that the toxins linger in our body longer. This can increase the risk of harm that alcohol has on our cells and organs. While one drink may not make a significant difference, one drink on every flight (especially if we’re frequent fliers) can lead to an increased risk of alcohol-related health conditions. Does this mean we should completely avoid it?

Should You Drink While In the Air?

While drinking on a flight is quite prevalent, it’s associated with greater risks than drinking at ground level (although there’s already an extensive list of risks associated with drinking regularly). 

There are plenty of alternatives to help us relax if we’re nervous fliers. And there are plenty of other activities and non-alcoholic beverages that can kick off a vacation. 

How Much Is Too Much?

Since alcohol affects us all differently, there’s no set amount of alcohol that is deemed “safe” or “ok” for in-flight consumption. If we do decide to drink, it’s best to follow moderate consumption guidelines. 

Moderate drinking guidelines suggest no more than two drinks in a day for men and no more than one drink in a day for women. Since drinking in-flight can be associated with even greater risks, even moderate consumption can be associated with greater consequences than drinking regularly. Let’s get a better idea of the unique risks of drinking while in the air.

Risks of Drinking While in the Air 

Due to the specific environment of a plane cabin, drinking has additional risks in comparison to drinking on ground level:

  • Increased dehydration. The low humidity of the cabin air and the diuretic properties of alcohol can cause increased dehydration. 
  • Sleep disruptions. Flights can be draining, especially if we’re on a red-eye flight, and sleep is crucial. Alcohol can cause further sleep disruptions to what’s an already uncomfortable sleeping experience.
  • Worse hangovers. Drinking on planes is associated with worse hangovers due to the cabin environment. Increased dehydration and slowed alcohol metabolism can lead to a more unpleasant aftermath.
  • Increased motion sickness. Alcohol disrupts our vestibular system, which controls our balance. For those of us who are sensitive to motion sickness, drinking in-flight could make our symptoms worse. 
  • Behavior issues. Drinking lowers our inhibitions and impedes our judgment. Alcohol can also increase negative emotions such as frustration and anger, which can be aggravated due to the stress of flying on an airplane. Drinking problems have led to increased in-flight incidents including fights and unruly behavior.
  • Safety concerns. Since drinking impacts our inhibitions and judgment, we are more likely to engage in risky behaviors. This can lead to low adherence to safety regulations, such as keeping our seatbelts on or following emergency protocols.

The environment of a plane cabin can heighten the risks of alcohol. If we choose to drink, we can minimize the risks by practicing mindful drinking.

Risks of Drinking in the Air

Responsible Drinking Tips for Your Next Flight

Practicing mindful consumption while flying can help us prioritize our health and well-being while avoiding an unpleasant aftermath. We can implement strategies to practice responsible drinking while flying:

  • Set limits. The ease of ordering drink after drink can quickly get out of hand. Stick to one drink when choosing to consume alcohol in-flight. 
  • Stay hydrated. Drinking plenty of water and replenishing hydration with electrolytes can help combat dehydration from alcohol and the low humidity of the cabin air.
  • Choose alternatives. Airlines offer plenty of non-alcoholic options. Try mixing cranberry juice and soda water together to make a quick mocktail. We can also keep busy by reading a book or watching a movie. 
  • Maintain nutrition. Depending on the airline and flight, sometimes only snacks are provided. Bringing a meal or eating beforehand helps us avoid drinking on an empty stomach.

Excessive drinking anywhere can be detrimental to our health. Implementing these mindful drinking strategies on and off the plane can help us develop a more positive relationship with alcohol.

Touching Down

Drinking while flying is often associated with “just taking the edge off” or “kicking off the party early,” but it does more harm than good. Although being in the air doesn’t affect the actual potency of alcohol, the unique environment of a plane cabin adds to the risks of alcohol. Put on your favorite show and mix up a fun mocktail to prevent the heightened risks of drinking in the air. Say goodbye to feeling unwell by avoiding alcohol when you fly!

Alcohol and Health
2024-10-04 9:00
Alcohol and Health
Potential Pregnancy Complications From Drinking Prior to Pregnancy
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Alcohol can cause pregnancy complications even prior to conception. Check out our latest blog for more info on alcohol’s pre-pregnancy effects and how to prevent them.

13 min read

Manage All Facets of Health With Reframe!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

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The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!

Read Full Article  →

You might be gearing up for one of the most transformative chapters of your life: pregnancy. You’re trying to do everything right — eating well, taking prenatal vitamins, and staying active. But what if the choices you made before your pregnancy even began could still cast a shadow on this new journey?

Before you pop the champagne on the journey to parenthood, it’s crucial to understand how drinking before pregnancy could impact the future of your child. Let’s explore the potential complications that can arise from pre-pregnancy drinking and how you can ensure a healthy start for you and your baby.

Chronic Drinking Consequences: How Prior Drinking Affects Pregnancy

A pregnant woman and a glass of wine

Alcohol impacts various stages of pregnancy including prior to conception. Understanding how helps protect the well-being of the mother and the baby. 

Alcohol and Fertility

Alcohol significantly affects fertility for both women and men, making it more difficult to conceive. For women, alcohol causes hormonal imbalances, leading to irregular menstrual cycles and even periods without ovulation (anovulation). Alcohol can also impair the health of our eggs. All of this means that alcohol can make it more difficult to become pregnant. It also can impair the success and health of the fetus. But alcohol doesn’t affect only women or the potential mother. 

For men, alcohol impacts fertility by reducing levels of testosterone, which is essential for healthy sperm production. Regular drinking is associated with lower sperm count and decreased sperm motility, which can impact successful conception. Research shows that even moderate alcohol consumption affects fertility. So, if you’re ready to start this new chapter of your life, making more mindful decisions about drinking can be a significant step towards a healthy future.

Tips for a Healthy Pregnancy 

Alcohol and Conception

Conception refers to the moment when the sperm fertilizes the egg. It’s the first step of the pregnancy process but won’t lead to pregnancy unless implantation occurs. Implantation is when the fertilized egg attaches to the uterine lining. If implantation is successful, the pregnancy begins. It’s estimated that 50% of fertilized eggs don’t implant. On top of that, alcohol can interfere with the implantation process, making that percentage even lower. 

Drinking also alters the hormonal balance and disrupts the endometrial lining, which is crucial for the embryo to grow and thrive. Studies show that drinking after conception increases the risk of miscarriage and complications in fetal development. One study found that alcohol increases the risk of macrosomia and growth retardation, which are correlated with maternal metabolic disorders. Most of the time, women don’t find out they’re pregnant days or even weeks after conception, so they might continue to drink, not knowing that they’re harming the health of their pregnancy. But it doesn’t end here.

Drinking during the early stages of pregnancy also impacts the health of the mother. Maternal metabolic disorders such as obesity, hypertension, and gestational diabetes can have adverse long-term effects on the mother’s health, as they increase the risk of other health complications. Although conception is the first step of pregnancy, the serious consequences of drinking during this period underline the importance of avoiding alcohol during this time.

Drinking During Pregnancy

We’ve discussed drinking during the early stages of pregnancy, but drinking later on in the pregnancy is just as dangerous. Alcohol can cross the placenta and enter the baby’s bloodstream, interfering with critical stages of fetal development. The result could be a range of physical, behavioral, and cognitive impairments known as fetal alcohol syndrome disorders (FASDs).

FASDs can range from cognitive and behavioral problems, such as developmental delays, learning disabilities, and difficulties with attention and impulse control. Possible physical abnormalities include facial dysmorphia, growth deficiencies, and organ malformations. All of these severely impact the health and well-being of the child far beyond childhood

Studies show that even low-to-moderate alcohol consumption can affect fetal brain development and cause long-term effects on cognitive and emotional functioning. 

As we’ve learned, alcohol during pregnancy and even before the pregnancy can have lasting impacts on both the mother’s and baby’s health. But when is the right time to stop drinking?

When To Stop Drinking Before Pregnancy

While there is no exact timeframe to stop drinking before pregnancy that will eliminate all complications, generally, the earlier the better. An analysis on prenatal alcohol consumption suggests that women should stop drinking a year before conception and men should stop drinking at least 6 months before conception. 

But this gets a bit complicated, as sometimes it’s not an intentional decision to get pregnant. So, for women and men who are of childbearing age, sexually active, and aren’t using birth control, quitting or cutting back on alcohol is a good idea. Not only is it beneficial to your own health and well-being, but it’ll be beneficial when you do decide to start a family. 

What To Do If You Drank Before Realizing You’re Pregnant

Pregnancy is already stressful. The last thing we need is to freak ourselves out even more. If you’ve been drinking alcohol before you found out you’re pregnant, it’s important to stop immediately. Continuing to drink will only do more harm. 

It’s also important to schedule a medical appointment with your doctor. They may choose to run tests or use imaging to check the baby’s health. During this time it’s crucial to communicate with your doctor that you’ve consumed alcohol and that you’re concerned about your baby’s health. Having all the information will help them run the necessary diagnostics and develop a treatment plan if needed. They’re not there to judge you — they’re there to help!

Tips for a Healthy Pregnancy 

A healthy pregnancy can benefit from steps we take long before we’re pregnant. Now that we’ve learned about alcohol’s effects on pregnancy, let’s set ourselves up for success with these healthy practices: 

  • Eat well. Eat a balanced diet and avoid foods that can be dangerous such as raw fish, processed meats, and unpasteurized foods. 
  • Stay hydrated. Pregnant women require even more water than usual. Proper hydration helps the baby get essential nutrients, assists with building new tissue, aids digestion, and provides energy. It’s recommended you drink about 8 to 12 cups of water per day.
  • Stay active. Exercise gets our blood flowing more, which can be beneficial to deliver nutrients to the baby. It can also aid with pregnancy symptoms such as constipation, pain, and swelling. 
  • Get medical care. Proper medical care supports the health of the mother and the baby. Schedule regular checkups to reduce the risk of complications and treat prenatal issues before they get more serious.
  • Avoid harmful substances. Harmful substances like alcohol and other drugs are detrimental to the baby’s health and development (not to mention our own health!). 
  • Prioritize rest. We’re nurturing another human in our body, and that’s hard work. Getting adequate rest supports our baby’s health and our own. 

These positive habits apply to more than just women looking to get pregnant or who are already pregnant. Having a healthy lifestyle is beneficial for everyone! And while these tips increase the chance of a healthy pregnancy, a positive lifestyle overall is key!

A Healthy Start

The choices we make before pregnancy can have a lasting impact on our future health and the well-being of our children. Drinking before pregnancy increases the risk of pregnancy complications, impacts fetal development, and can lead to our own health issues. While there isn’t an exact amount of time determined, it’s recommended to stop drinking at least 6 months to a year before conception. However, for those who aren’t intentionally trying to conceive, things can get even trickier. Quit or cut back on alcohol not only to embrace a healthier lifestyle but also to set the stage for a positive and thriving pregnancy.

You might be gearing up for one of the most transformative chapters of your life: pregnancy. You’re trying to do everything right — eating well, taking prenatal vitamins, and staying active. But what if the choices you made before your pregnancy even began could still cast a shadow on this new journey?

Before you pop the champagne on the journey to parenthood, it’s crucial to understand how drinking before pregnancy could impact the future of your child. Let’s explore the potential complications that can arise from pre-pregnancy drinking and how you can ensure a healthy start for you and your baby.

Chronic Drinking Consequences: How Prior Drinking Affects Pregnancy

A pregnant woman and a glass of wine

Alcohol impacts various stages of pregnancy including prior to conception. Understanding how helps protect the well-being of the mother and the baby. 

Alcohol and Fertility

Alcohol significantly affects fertility for both women and men, making it more difficult to conceive. For women, alcohol causes hormonal imbalances, leading to irregular menstrual cycles and even periods without ovulation (anovulation). Alcohol can also impair the health of our eggs. All of this means that alcohol can make it more difficult to become pregnant. It also can impair the success and health of the fetus. But alcohol doesn’t affect only women or the potential mother. 

For men, alcohol impacts fertility by reducing levels of testosterone, which is essential for healthy sperm production. Regular drinking is associated with lower sperm count and decreased sperm motility, which can impact successful conception. Research shows that even moderate alcohol consumption affects fertility. So, if you’re ready to start this new chapter of your life, making more mindful decisions about drinking can be a significant step towards a healthy future.

Tips for a Healthy Pregnancy 

Alcohol and Conception

Conception refers to the moment when the sperm fertilizes the egg. It’s the first step of the pregnancy process but won’t lead to pregnancy unless implantation occurs. Implantation is when the fertilized egg attaches to the uterine lining. If implantation is successful, the pregnancy begins. It’s estimated that 50% of fertilized eggs don’t implant. On top of that, alcohol can interfere with the implantation process, making that percentage even lower. 

Drinking also alters the hormonal balance and disrupts the endometrial lining, which is crucial for the embryo to grow and thrive. Studies show that drinking after conception increases the risk of miscarriage and complications in fetal development. One study found that alcohol increases the risk of macrosomia and growth retardation, which are correlated with maternal metabolic disorders. Most of the time, women don’t find out they’re pregnant days or even weeks after conception, so they might continue to drink, not knowing that they’re harming the health of their pregnancy. But it doesn’t end here.

Drinking during the early stages of pregnancy also impacts the health of the mother. Maternal metabolic disorders such as obesity, hypertension, and gestational diabetes can have adverse long-term effects on the mother’s health, as they increase the risk of other health complications. Although conception is the first step of pregnancy, the serious consequences of drinking during this period underline the importance of avoiding alcohol during this time.

Drinking During Pregnancy

We’ve discussed drinking during the early stages of pregnancy, but drinking later on in the pregnancy is just as dangerous. Alcohol can cross the placenta and enter the baby’s bloodstream, interfering with critical stages of fetal development. The result could be a range of physical, behavioral, and cognitive impairments known as fetal alcohol syndrome disorders (FASDs).

FASDs can range from cognitive and behavioral problems, such as developmental delays, learning disabilities, and difficulties with attention and impulse control. Possible physical abnormalities include facial dysmorphia, growth deficiencies, and organ malformations. All of these severely impact the health and well-being of the child far beyond childhood

Studies show that even low-to-moderate alcohol consumption can affect fetal brain development and cause long-term effects on cognitive and emotional functioning. 

As we’ve learned, alcohol during pregnancy and even before the pregnancy can have lasting impacts on both the mother’s and baby’s health. But when is the right time to stop drinking?

When To Stop Drinking Before Pregnancy

While there is no exact timeframe to stop drinking before pregnancy that will eliminate all complications, generally, the earlier the better. An analysis on prenatal alcohol consumption suggests that women should stop drinking a year before conception and men should stop drinking at least 6 months before conception. 

But this gets a bit complicated, as sometimes it’s not an intentional decision to get pregnant. So, for women and men who are of childbearing age, sexually active, and aren’t using birth control, quitting or cutting back on alcohol is a good idea. Not only is it beneficial to your own health and well-being, but it’ll be beneficial when you do decide to start a family. 

What To Do If You Drank Before Realizing You’re Pregnant

Pregnancy is already stressful. The last thing we need is to freak ourselves out even more. If you’ve been drinking alcohol before you found out you’re pregnant, it’s important to stop immediately. Continuing to drink will only do more harm. 

It’s also important to schedule a medical appointment with your doctor. They may choose to run tests or use imaging to check the baby’s health. During this time it’s crucial to communicate with your doctor that you’ve consumed alcohol and that you’re concerned about your baby’s health. Having all the information will help them run the necessary diagnostics and develop a treatment plan if needed. They’re not there to judge you — they’re there to help!

Tips for a Healthy Pregnancy 

A healthy pregnancy can benefit from steps we take long before we’re pregnant. Now that we’ve learned about alcohol’s effects on pregnancy, let’s set ourselves up for success with these healthy practices: 

  • Eat well. Eat a balanced diet and avoid foods that can be dangerous such as raw fish, processed meats, and unpasteurized foods. 
  • Stay hydrated. Pregnant women require even more water than usual. Proper hydration helps the baby get essential nutrients, assists with building new tissue, aids digestion, and provides energy. It’s recommended you drink about 8 to 12 cups of water per day.
  • Stay active. Exercise gets our blood flowing more, which can be beneficial to deliver nutrients to the baby. It can also aid with pregnancy symptoms such as constipation, pain, and swelling. 
  • Get medical care. Proper medical care supports the health of the mother and the baby. Schedule regular checkups to reduce the risk of complications and treat prenatal issues before they get more serious.
  • Avoid harmful substances. Harmful substances like alcohol and other drugs are detrimental to the baby’s health and development (not to mention our own health!). 
  • Prioritize rest. We’re nurturing another human in our body, and that’s hard work. Getting adequate rest supports our baby’s health and our own. 

These positive habits apply to more than just women looking to get pregnant or who are already pregnant. Having a healthy lifestyle is beneficial for everyone! And while these tips increase the chance of a healthy pregnancy, a positive lifestyle overall is key!

A Healthy Start

The choices we make before pregnancy can have a lasting impact on our future health and the well-being of our children. Drinking before pregnancy increases the risk of pregnancy complications, impacts fetal development, and can lead to our own health issues. While there isn’t an exact amount of time determined, it’s recommended to stop drinking at least 6 months to a year before conception. However, for those who aren’t intentionally trying to conceive, things can get even trickier. Quit or cut back on alcohol not only to embrace a healthier lifestyle but also to set the stage for a positive and thriving pregnancy.

Alcohol and Health